Important roles of PI3Kγ in osteoclastogenesis and bone homeostasis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 29, 2010, Pages 12901-12906

  Kang, Heeseog ^a   Chang, Woochul ^a   Hurley, Marja ^b   Vignery, Agnès ^a   Wu, Dianqing ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Apoptosis; Chemokine; Signaling

Indexed keywords

CHEMOKINE RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; CHEMOKINE; ISOENZYME; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3-KINASE GAMMA; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE; BONE MASS; DOWN REGULATION; HOMEOSTASIS; MALE; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; ANIMAL; BONE DEVELOPMENT; BONE MARROW CELL; C57BL MOUSE; CELL COUNT; CYTOLOGY; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; GENE DELETION; MACROPHAGE; METABOLISM; MOUSE MUTANT; ORGAN SIZE; PHOSPHORYLATION;

MUS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; BONE AND BONES; BONE MARROW CELLS; CELL COUNT; CHEMOKINES; DOWN-REGULATION; ENZYME ACTIVATION; GENE DELETION; HOMEOSTASIS; ISOENZYMES; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORGAN SIZE; OSTEOCLASTS; OSTEOGENESIS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 77955608243     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1001499107     Document Type: Article

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