-
1
-
-
0027466461
-
Gastroprotective effect of zinc acexamate against damage induced by nonsteroidal anti- inflammatory drugs: A morphological study
-
Bulbena O, Escolar G, Navarro C, et al. Gastroprotective effect of zinc acexamate against damage induced by nonsteroidal anti- inflammatory drugs: A morphological study. Dig Dis Sci. 1993; 38: 730-39.
-
(1993)
Dig Dis Sci
, vol.38
, pp. 730-739
-
-
Bulbena, O.1
Escolar, G.2
Navarro, C.3
-
2
-
-
47249113967
-
The effects of physical and psychological stress on the gastro-intestinal tract: Lessons from animal models
-
Caso JR, Leza JC, Menchén L. The effects of physical and psychological stress on the gastro-intestinal tract: lessons from animal models. Curr Mol Med. 2008; 8: 299-312.
-
(2008)
Curr Mol Med
, vol.8
, pp. 299-312
-
-
Caso, J.R.1
Leza, J.C.2
Menchén, L.3
-
3
-
-
0024326791
-
Pharmacokinetics of naloxone: An insight into the locus of effect on stress-ulceration
-
Kleiman-Wexler RL, Adair CG, Ephgrave KS. Pharmacokinetics of naloxone: an insight into the locus of effect on stress-ulceration. J Pharmacol Exp Ther. 1989; 251: 435-8.
-
(1989)
J Pharmacol Exp Ther
, vol.251
, pp. 435-438
-
-
Kleiman-Wexler, R.L.1
Adair, C.G.2
Ephgrave, K.S.3
-
4
-
-
0030782286
-
Circadian reactivity rhythm of rat gastric mucosa to restraint-cold stress and indomethacin: Temporal variation in the protective effect of iloprost
-
Savran B, Görgün CZ, Zengil H. Circadian reactivity rhythm of rat gastric mucosa to restraint-cold stress and indomethacin: Temporal variation in the protective effect of iloprost. Chronobio Int. 1997; 14: 575-583.
-
(1997)
Chronobio Int
, vol.14
, pp. 575-583
-
-
Savran, B.1
Görgün, C.Z.2
Zengil, H.3
-
5
-
-
0021863720
-
Naloxone is protective against indomethacin-induced intestinal ulceration in the rat
-
Waisman Y, Dinari G, Marcus H, et al. Naloxone is protective against indomethacin-induced intestinal ulceration in the rat. Gastroenterology. 1985; 89: 86-91.
-
(1985)
Gastroenterology
, vol.89
, pp. 86-91
-
-
Waisman, Y.1
Dinari, G.2
Marcus, H.3
-
6
-
-
0015237292
-
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin like drugs
-
Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin like drugs. Nature 1971; 231: 232-5.
-
(1971)
Nature
, vol.231
, pp. 232-235
-
-
Vane, J.R.1
-
7
-
-
77955547123
-
Mechanism of nonsteroidal anti-inflammatory drugs
-
Vane JR. Mechanism of nonsteroidal anti-inflammatory drugs. Am J Med. 1998; 104: 25-85.
-
(1998)
Am J Med
, vol.104
, pp. 25-85
-
-
Vane, J.R.1
-
8
-
-
0031680203
-
Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: Efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects
-
Simon LS, Lanza FL, Lipsky PE, et al. Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects. Arthritis Rheum. 1998; 41: 1591-602.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 1591-1602
-
-
Simon, L.S.1
Lanza, F.L.2
Lipsky, P.E.3
-
9
-
-
0028926813
-
New insights into the mode of action of anti-inflammatory drugs
-
Vane JR, Botting RM. New insights into the mode of action of anti-inflammatory drugs. Inflamm Res. 1995; 44: 1-10.
-
(1995)
Inflamm Res
, vol.44
, pp. 1-10
-
-
Vane, J.R.1
Botting, R.M.2
-
10
-
-
34147168634
-
Inhibitors of cyclooxygenases: Mechanisms, selectivity and uses
-
Botting RM. Inhibitors of cyclooxygenases: mechanisms, selectivity and uses. J Physiol Pharmacol. 2006; 57: 113-24.
-
(2006)
J Physiol Pharmacol
, vol.57
, pp. 113-124
-
-
Botting, R.M.1
-
11
-
-
0022407333
-
The role of endogenous prostaglandins in the regulation of gastric secretion in rhesus monkeys
-
El-Bayer H, Steel L, Montcalm E, et al. The role of endogenous prostaglandins in the regulation of gastric secretion in rhesus monkeys. Prostaglandins. 1985; 30: 401-17.
-
(1985)
Prostaglandins
, vol.30
, pp. 401-417
-
-
El-Bayer, H.1
Steel, L.2
Montcalm, E.3
-
12
-
-
0022006152
-
Prostaglandin protection of rat colonic mucosa from damage induced by ethanol
-
Wallace JL, Whittle BJ, Boughton-Smith NK. Prostaglandin protection of rat colonic mucosa from damage induced by ethanol. Dig Dis Sci. 1985; 30: 866-76.
-
(1985)
Dig Dis Sci
, vol.30
, pp. 866-876
-
-
Wallace, J.L.1
Whittle, B.J.2
Boughton-Smith, N.K.3
-
13
-
-
70449470692
-
Evaluation of gastric toxicity of indomethacin acid, salt form and complexed forms with hydroxypropyl-β-cyclodextrin on Wistar rats: Histopathologic analysis
-
Ribeiro-Rama AC, Figueiredo IV, Veiga F, et al. Evaluation of gastric toxicity of indomethacin acid, salt form and complexed forms with hydroxypropyl-β-cyclodextrin on Wistar rats: Histopathologic analysis. Fund Clin Pharmacol. 2009; 23: 747-55.
-
(2009)
Fund Clin Pharmacol
, vol.23
, pp. 747-755
-
-
Ribeiro-Rama, A.C.1
Figueiredo, I.V.2
Veiga, F.3
-
14
-
-
0015624247
-
Mechanism of ulcerogenic activity of indomethacin and oxyphenbutazone
-
Bhargava KP, Gupta MB, Tangri KK. Mechanism of ulcerogenic activity of indomethacin and oxyphenbutazone. Eur J Pharmacol. 1973; 22: 191-5.
-
(1973)
Eur J Pharmacol
, vol.22
, pp. 191-195
-
-
Bhargava, K.P.1
Gupta, M.B.2
Tangri, K.K.3
-
15
-
-
0025668492
-
Cyclodextrin properties and applications
-
Szejtli J. Cyclodextrin properties and applications. Drug Invest. 1990; 2: 11-21.
-
(1990)
Drug Invest
, vol.2
, pp. 11-21
-
-
Szejtli, J.1
-
16
-
-
0025649650
-
New perspectives in cyclodextrin pharmaceutical applications: Cyclodextrin derivatives as new drug carriers
-
Uekama K, Irie T. New perspectives in cyclodextrin pharmaceutical applications: Cyclodextrin derivatives as new drug carriers. Drug Invest. 1990; 2: 22-8.
-
(1990)
Drug Invest
, vol.2
, pp. 22-28
-
-
Uekama, K.1
Irie, T.2
-
17
-
-
0031054513
-
Pharmaceutical applications of cyclodextrins. III. Toxicological issues and safety evaluation
-
Irie T, Uekama K. Pharmaceutical applications of cyclodextrins. III. Toxicological issues and safety evaluation. J Pharm Sci. 1997; 86: 147-62.
-
(1997)
J Pharm Sci
, vol.86
, pp. 147-162
-
-
Irie, T.1
Uekama, K.2
-
20
-
-
40849085495
-
Preparation of amorphous indomethacin from aqueous 2,6-di-O-methyl- β-CD solution
-
Iohara D, Hirayama F, Ishiguro T, et al. Preparation of amorphous indomethacin from aqueous 2,6-di-O-methyl- β-CD solution. Int J Pharm. 2008; 354: 70-6.
-
(2008)
Int J Pharm
, vol.354
, pp. 70-76
-
-
Iohara, D.1
Hirayama, F.2
Ishiguro, T.3
-
21
-
-
0028324016
-
In vivo evaluation of indomethacin/cyclodextrin complexes gastrointestinal tolerance and dermal antiiflammatory activity
-
Lin SZ, Wouessidjewe D, Poelman MC, et al. In vivo evaluation of indomethacin/cyclodextrin complexes gastrointestinal tolerance and dermal antiiflammatory activity. Int J Pharm. 1994; 106: 63-7.
-
(1994)
Int J Pharm
, vol.106
, pp. 63-67
-
-
Lin, S.Z.1
Wouessidjewe, D.2
Poelman, M.C.3
-
22
-
-
0347651904
-
The physicochemical characteristics and bioavailability of indomethacin from β-CD, hydroxyethyl β-CD and HP-β-CD complexes
-
Jambhekar S, Casella R, Maher T. The physicochemical characteristics and bioavailability of indomethacin from β-CD, hydroxyethyl β-CD and HP-β-CD complexes. Int J Pharm. 2004; 270: 149-66.
-
(2004)
Int J Pharm
, vol.270
, pp. 149-166
-
-
Jambhekar, S.1
Casella, R.2
Maher, T.3
-
23
-
-
0025146392
-
Effect of cyclodextrin derivatives on indomethacin stability in aqueous solution
-
Backensfeld T, Müller BW, Wiese M, et al. Effect of cyclodextrin derivatives on indomethacin stability in aqueous solution. Pharm Res. 1990; 7: 484-90.
-
(1990)
Pharm Res
, vol.7
, pp. 484-490
-
-
Backensfeld, T.1
Müller, B.W.2
Wiese, M.3
-
24
-
-
0025352221
-
High field nuclear magnetic resonance techniques for the investigation of a β-cyclodextrin:Indomethacin inclusion complex
-
Djedaini F, Lin SZ, Perly B, et al. High field nuclear magnetic resonance techniques for the investigation of a β-cyclodextrin:indomethacin inclusion complex. J Pharm Sci. 1990; 79: 643-6.
-
(1990)
J Pharm Sci
, vol.79
, pp. 643-646
-
-
Djedaini, F.1
Lin, S.Z.2
Perly, B.3
-
25
-
-
0034887576
-
Cyclodextrin complexes of salts of acidic drugs: Thermodynamic properties, structural features, and pharmaceutical applications
-
Redenti E, Szente L, Szejtli J. Cyclodextrin complexes of salts of acidic drugs: Thermodynamic properties, structural features, and pharmaceutical applications. J Pharm Sci. 2001; 90: 979-86.
-
(2001)
J Pharm Sci
, vol.90
, pp. 979-986
-
-
Redenti, E.1
Szente, L.2
Szejtli, J.3
-
27
-
-
0020576802
-
Pharmacokinetics of piroxicam in man
-
Hobbs DC. Pharmacokinetics of piroxicam in man. Eur J Rheumatol Inflamm. 1983; 6: 46-55.
-
(1983)
Eur J Rheumatol Inflamm
, vol.6
, pp. 46-55
-
-
Hobbs, D.C.1
-
28
-
-
9644254189
-
Multicomponent complexes of piroxicam with cyclodextrins and HPMC
-
Jug M, Becirevic-Lacan M. Multicomponent complexes of piroxicam with cyclodextrins and HPMC. Drug Dev Ind Pharm. 2004; 30: 1051-60.
-
(2004)
Drug Dev Ind Pharm
, vol.30
, pp. 1051-1060
-
-
Jug, M.1
Becirevic-Lacan, M.2
-
29
-
-
27144489696
-
Influence of cyclodextrin complexation on piroxicam gel formulations
-
Jug M, Becirevic-Lacan M, Kwokal A, et al. Influence of cyclodextrin complexation on piroxicam gel formulations. Acta Pharma. 2005; 55: 223-36.
-
(2005)
Acta Pharma
, vol.55
, pp. 223-236
-
-
Jug, M.1
Becirevic-Lacan, M.2
Kwokal, A.3
-
31
-
-
31544461788
-
Characterization of the transdermal transport of flurbiprofen and indomethacin
-
Qing L, Hiroyuki T, Yukio K, et al. Characterization of the transdermal transport of flurbiprofen and indomethacin. J Control Rel. 2006; 110: 542-556.
-
(2006)
J Control Rel
, vol.110
, pp. 542-556
-
-
Qing, L.1
Hiroyuki, T.2
Yukio, K.3
-
32
-
-
0034665497
-
Effect of fatty acid esters on permeation of ketoprofen through hairless rat skin
-
Fujii M, Hori N, Shiozawa K, Wakabayashi K, Kawahara E, Matsumoto M. Effect of fatty acid esters on permeation of ketoprofen through hairless rat skin. Int J Pharm. 2000; 205: 117-125.
-
(2000)
Int J Pharm
, vol.205
, pp. 117-125
-
-
Fujii, M.1
Hori, N.2
Shiozawa, K.3
Wakabayashi, K.4
Kawahara, E.5
Matsumoto, M.6
-
33
-
-
0036744772
-
Enhanced percutaneous absorption of piroxicam via salt formation with ethanolamines
-
Cheong H-A, Choi H-K. Enhanced percutaneous absorption of piroxicam via salt formation with ethanolamines. Pharm Res. 2002; 19:1375-80.
-
(2002)
Pharm Res
, vol.19
, pp. 1375-1380
-
-
Cheong, H.-A.1
Choi, H.-K.2
-
35
-
-
0031884213
-
Effects of inhibition of prostaglandin endoperoxide synthase-2 in chronic gastro- intestinal ulcer models in rats
-
Schmassmann A, Peskar BM, Selter C, et al. Effects of inhibition of prostaglandin endoperoxide synthase-2 in chronic gastro- intestinal ulcer models in rats. Br J Pharmacol. 1998; 123: 795-804.
-
(1998)
Br J Pharmacol
, vol.123
, pp. 795-804
-
-
Schmassmann, A.1
Peskar, B.M.2
Selter, C.3
-
36
-
-
0035369328
-
Classic NSAID and selective cyclooxygenase (COX)-1 and COX-2 inhibitors in healing of chronic gastric ulcers
-
Brzozowski T, Konturek PC, Konturek SJ, et al. Classic NSAID and selective cyclooxygenase (COX)-1 and COX-2 inhibitors in healing of chronic gastric ulcers. Microsc Res Tech. 2001; 1: 343-53.
-
(2001)
Microsc Res Tech
, vol.1
, pp. 343-353
-
-
Brzozowski, T.1
Konturek, P.C.2
Konturek, S.J.3
-
37
-
-
0036128096
-
A comparative study on the activity of lansoprazole, omeprazole and PD-136450 on acidified ethanol- and indomethacin-induced gastric lesions in the rat
-
Chandranath SI, Bastaki SM, Singh JA. A comparative study on the activity of lansoprazole, omeprazole and PD-136450 on acidified ethanol- and indomethacin-induced gastric lesions in the rat. Clin Exp Pharmacl Physiol. 2002; 29: 173-80.
-
(2002)
Clin Exp Pharmacl Physiol
, vol.29
, pp. 173-180
-
-
Chandranath, S.I.1
Bastaki, S.M.2
Singh, J.A.3
-
38
-
-
0030459695
-
Tachykinin-induced increase in gastric mucosal resistance: Role of primary afferent neurons, CGRP, and NO
-
Stroff T, Plate S, Ebrahim SJ, et al. Tachykinin-induced increase in gastric mucosal resistance: role of primary afferent neurons, CGRP, and NO. Am J Physiol. 1996; 271: G1017-27.
-
(1996)
Am J Physiol
, vol.271
-
-
Stroff, T.1
Plate, S.2
Ebrahim, S.J.3
-
39
-
-
0035714624
-
Neural aspects of prostaglandin involvement in gastric mucosal defense
-
Peskar BM. Neural aspects of prostaglandin involvement in gastric mucosal defense. J Physiol Pharmacol. 2001; 52: 555-68.
-
(2001)
J Physiol Pharmacol
, vol.52
, pp. 555-568
-
-
Peskar, B.M.1
-
40
-
-
0031932549
-
Selective cyclo- oxygenase-2 inhibitors and their influence on the protective effect of a mild irritant in the rat stomach
-
Gretzer B, Ehrlich K, Maricic N, et al. Selective cyclo- oxygenase-2 inhibitors and their influence on the protective effect of a mild irritant in the rat stomach. Br J Pharmacol. 1998; 123: 927-35.
-
(1998)
Br J Pharmacol
, vol.123
, pp. 927-935
-
-
Gretzer, B.1
Ehrlich, K.2
Maricic, N.3
-
41
-
-
0037005742
-
Interaction of cyclooxygenase- 2 inhibitors and salicylate in gastric mucosal damage
-
Peskar BM, Ehrlich K, Peskar BA. Interaction of cyclooxygenase- 2 inhibitors and salicylate in gastric mucosal damage. Eur J Pharmacol. 2002; 434: 65-70.
-
(2002)
Eur J Pharmacol
, vol.434
, pp. 65-70
-
-
Peskar, B.M.1
Ehrlich, K.2
Peskar, B.A.3
-
42
-
-
28744434722
-
Role of mucus in the repair of gastric epithelial damage in rat
-
Wallace JL, Whittle BJR. Role of mucus in the repair of gastric epithelial damage in rat. Gastroenterology. 1985; 91: 611-30.
-
(1985)
Gastroenterology
, vol.91
, pp. 611-630
-
-
Wallace, J.L.1
Whittle, B.J.R.2
-
43
-
-
0021850180
-
Relations between gastric irritancy/ ulcerogenicity and anti-oedemic activity of non-steroidal anti-inflammatory drugs
-
Rainsford KD. Relations between gastric irritancy/ ulcerogenicity and anti-oedemic activity of non-steroidal anti-inflammatory drugs. J Pharm Pharmacol. 1985; 37: 678-9.
-
(1985)
J Pharm Pharmacol
, vol.37
, pp. 678-679
-
-
Rainsford, K.D.1
-
44
-
-
67349227426
-
Synthesis and investigation of anti-inflammatory activity and gastric ulcerogenicity of novel nitric oxide-donating pyrazoline derivatives
-
Shoman ME, Abdel-Aziz M, Aly OM, et al. Synthesis and investigation of anti-inflammatory activity and gastric ulcerogenicity of novel nitric oxide-donating pyrazoline derivatives. Eur J Med Chem. 2009; 44: 3068-76.
-
(2009)
Eur J Med Chem
, vol.44
, pp. 3068-3076
-
-
Shoman, M.E.1
Abdel-Aziz, M.2
Aly, O.M.3
-
45
-
-
75749154091
-
Gastroprotective effects of telmisartan on experimentally-induced gastric ulcers in rats
-
Morsy M, Ashour O, Amin E, et al. Gastroprotective effects of telmisartan on experimentally-induced gastric ulcers in rats. Pharmazie. 2009; 64: 590-4.
-
(2009)
Pharmazie
, vol.64
, pp. 590-594
-
-
Morsy, M.1
Ashour, O.2
Amin, E.3
-
46
-
-
0347990721
-
Oxidative stress and antioxidants status in peptic ulcer and gastric carcinoma
-
Tandon R, Khanna HD, Dorababu M, et al. Oxidative stress and antioxidants status in peptic ulcer and gastric carcinoma. Indian J Physiol Pharmacol. 2004; 48: 115-8.
-
(2004)
Indian J Physiol Pharmacol
, vol.48
, pp. 115-118
-
-
Tandon, R.1
Khanna, H.D.2
Dorababu, M.3
-
47
-
-
33846785470
-
Preconditioning stress prevents cold restraint stress-induced gastric lesions in rats: Roles of COX-1, COX-2, and PLA2
-
Tanaka A, Hatazawa R, Takahira Y, et al. Preconditioning stress prevents cold restraint stress-induced gastric lesions in rats: roles of COX-1, COX-2, and PLA2. Dig Dis Sci. 2007; 52: 478-87.
-
(2007)
Dig Dis Sci
, vol.52
, pp. 478-487
-
-
Tanaka, A.1
Hatazawa, R.2
Takahira, Y.3
-
48
-
-
0025225730
-
Role of epidermal growth factor, prostaglandin, and sulfhydryls in stress-induced gastric lesions
-
Konturek PK, Brzozowski T, Konturek SJ, et al. Role of epidermal growth factor, prostaglandin, and sulfhydryls in stress-induced gastric lesions. Gastroenterology. 1990; 99: 1607-15.
-
(1990)
Gastroenterology
, vol.99
, pp. 1607-1615
-
-
Konturek, P.K.1
Brzozowski, T.2
Konturek, S.J.3
-
49
-
-
0027486087
-
Effect of stress on the antioxidant enzymes and gastric ulceration
-
Das D, Banerjee RK. Effect of stress on the antioxidant enzymes and gastric ulceration. Mol Cell Biochem. 1993; 125: 115-25.
-
(1993)
Mol Cell Biochem
, vol.125
, pp. 115-125
-
-
Das, D.1
Banerjee, R.K.2
-
50
-
-
0017058131
-
Stress ulcers: Their pathogenesis, diagnosis, and treatment
-
Moody FG, Cheung LY. Stress ulcers: their pathogenesis, diagnosis, and treatment. Surg Clin North Am. 1976; 56: 1469-78.
-
(1976)
Surg Clin North Am
, vol.56
, pp. 1469-1478
-
-
Moody, F.G.1
Cheung, L.Y.2
-
51
-
-
0026561387
-
Do perforated duodenal ulcers need an acid- decreasing surgical procedure now that omeprazole is available?
-
Feliciano DV. Do perforated duodenal ulcers need an acid- decreasing surgical procedure now that omeprazole is available? Surg Clin North Am. 1992; 72: 369-80.
-
(1992)
Surg Clin North Am
, vol.72
, pp. 369-380
-
-
Feliciano, D.V.1
-
52
-
-
0033601089
-
Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: A randomized controlled trial
-
Simon LS, Weaver AL, Graham DY, et al. Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: a randomized controlled trial. JAMA. 1999; 282: 1921-8.
-
(1999)
JAMA
, vol.282
, pp. 1921-1928
-
-
Simon, L.S.1
Weaver, A.L.2
Graham, D.Y.3
-
53
-
-
0034093534
-
Celecoxib: A review of its use in osteoarthritis, rheumatoid arthritis and acute pain
-
Clemett D, Goa KL. Celecoxib: a review of its use in osteoarthritis, rheumatoid arthritis and acute pain. Drugs. 2000; 59: 957-80.
-
(2000)
Drugs
, vol.59
, pp. 957-980
-
-
Clemett, D.1
Goa, K.L.2
-
54
-
-
0034644396
-
Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: The CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study
-
Silverstein FE, Faich G, Goldstein JL, et al. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study. JAMA. 2000; 284: 1247-55.
-
(2000)
JAMA
, vol.284
, pp. 1247-1255
-
-
Silverstein, F.E.1
Faich, G.2
Goldstein, J.L.3
|