Effect of fatty acid Esters on permeation of ketoprofen through hairless rat skin

International Journal of Pharmaceutics

Volumn 205, Issue 1-2, 2000, Pages 117-125

  Fujii, Makiko ^a   Hori, Naohide ^b   Shiozawa, Kumi ^a   Wakabayashi, Kyoko ^a   Kawahara, Emi ^a   Matsumoto, Mitsuo ^a  

^a SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

^b KISSEI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Diffusion constant; Fatty acid ester; Indomethacin; Ketoprofen; Partition coefficient; Skin permeation

Indexed keywords

DRUG VEHICLE; FATTY ACID ESTER; INDOMETACIN; ISONONANOIC ACID ISODECYL ESTER; ISONONANOIC ACID ISONONYL ESTER; ISONONANOIC ACID OCTYL ESTER; ISOPALMITIC ACID OCTYL ESTER; ISOSTEARIC ACID ISOCETYL ESTER; KETOPROFEN; LIQUID PARAFFIN; MYRISTIC ACID ISOCETYL ESTER; OCTANOIC ACID CETYL ESTER; OCTANOIC ACID ISOCETYL ESTER; PALMITIC ACID ISOCETYL ESTER; PALMITIC ACID OCTYL ESTER; STEARIC ACID ISOCETYL ESTER; UNCLASSIFIED DRUG; WATER;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DRUG PENETRATION; DRUG SOLUBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; RAT; RAT STRAIN; SKIN PERMEABILITY;

ANIMAL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ESTERS; FATTY ACIDS; INDOMETHACIN; KETOPROFEN; MALE; RATS; SKIN ABSORPTION; SOLUBILITY;

EID: 0034665497     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00496-8     Document Type: Article

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