Modulation of mammary cancer cell migration by 15-deoxy-Δ 12,14-prostaglandin J2: Implications for anti-metastatic therapy

Biochemical Journal

Volumn 430, Issue 1, 2010, Pages 69-78

  Diers, Anne R ^a,b   Dranka, Brian P ^a,b   Ricart, Karina C ^a,b   Oh, Joo Yeun ^a,b   Johnson, Michelle S ^a,b   Zhou, Fen ^a,b   Pallero, Manuel A ^a   Bodenstine, Thomas M ^a   Murphy Ullrich, Joanne E ^a,b,c   Welch, Danny R ^a,b,c,d   Landar, Aimee ^a,b  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d University of Alabama at Birmingham   (United States)

Author keywords

Actin cytoskeleton; Focal adhesion; Post translational proteinmodification; Reactive lipid species; Redox signalling; Thiol

Indexed keywords

ACTIN CYTOSKELETON; FOCAL ADHESIONS; POST-TRANSLATIONAL PROTEINMODIFICATION; REACTIVE LIPID SPECIES; REDOX SIGNALLING; THIOL;

ADHESION; CELLS; CYTOLOGY; FOCUSING; LIPIDS; PRESSURE EFFECTS;

PROTEINS;

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTIMETASTATIC AGENT; F ACTIN; FOCAL ADHESION KINASE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; 15 DEOXY DELTA(12,14) PROSTAGLANDIN J2; 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J2; ACTIN; ANTINEOPLASTIC AGENT; CYTOSKELETON PROTEIN; DRUG DERIVATIVE; FOCAL ADHESION KINASE 1; KEAP1 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROSTAGLANDIN D2; PTK2 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ARTICLE; BREAST CANCER; CANCER CELL; CANCER THERAPY; CELL MIGRATION; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; FOCAL ADHESION; METASTASIS; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN MODIFICATION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; ANIMAL; CELL MOTION; CELL SURVIVAL; DRUG ANTAGONISM; DRUG EFFECT; PHYSIOLOGY; TUMOR CELL LINE;

ACTINS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; CYTOSKELETAL PROTEINS; FOCAL ADHESION KINASE 1; FOCAL ADHESIONS; MICE; NEOPLASM METASTASIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROSTAGLANDIN D2; SIGNAL TRANSDUCTION;

EID: 77955503607     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20091193     Document Type: Article

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