메뉴 건너뛰기




Volumn 37, Issue 8, 2010, Pages 1646-1657

Raloxifene modulates estrogen-mediated B cell autoreactivity in NZB/W F1 mice

Author keywords

B cells; Estrogen; NZB W F1 mice; Raloxifene; Systemic lupus erythematosus

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD22 ANTIGEN; CD40 ANTIGEN; DOUBLE STRANDED DNA; DOUBLE STRANDED DNA ANTIBODY; ESTROGEN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G3; RALOXIFENE;

EID: 77955480480     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: 10.3899/jrheum.090911     Document Type: Article
Times cited : (18)

References (73)
  • 2
    • 0026329304 scopus 로고
    • Frequency of lupus flare in pregnancy. The Hopkins Lupus Pregnancy Center experience
    • Petri M, Howard D, Repke J. Frequency of lupus flare in pregnancy. The Hopkins Lupus Pregnancy Center experience. Arthritis Rheum 1991;34:1538-45.
    • (1991) Arthritis Rheum , vol.34 , pp. 1538-1545
    • Petri, M.1    Howard, D.2    Repke, J.3
  • 3
    • 0038079533 scopus 로고
    • Klinefelter's syndrome: Hormone metabolism in hypogonadal males with systemic lupus erythematosus
    • Lahita R, Bradlow H. Klinefelter's syndrome: hormone metabolism in hypogonadal males with systemic lupus erythematosus. J Rheumatol 1987;14:154-7.
    • (1987) J Rheumatol , vol.14 , pp. 154-157
    • Lahita, R.1    Bradlow, H.2
  • 4
  • 6
    • 0031881090 scopus 로고    scopus 로고
    • Postmenopausal estrogen replacement therapy and the risk of developing systemic lupus erythematosus or discoid lupus
    • Meier C, Sturkenboom M, Cohen A, Jick H. Postmenopausal estrogen replacement therapy and the risk of developing systemic lupus erythematosus or discoid lupus. J Rheumatol 1998;25:1515-9.
    • (1998) J Rheumatol , vol.25 , pp. 1515-1519
    • Meier, C.1    Sturkenboom, M.2    Cohen, A.3    Jick, H.4
  • 7
    • 0028351009 scopus 로고
    • Safety of hormone replacement therapy (HRT) in systemic lupus erythematosus (SLE)
    • Arden N, Lloyd M, Spector T, Hughes G. Safety of hormone replacement therapy (HRT) in systemic lupus erythematosus (SLE). Lupus 1994;3:11-3.
    • (1994) Lupus , vol.3 , pp. 11-13
    • Arden, N.1    Lloyd, M.2    Spector, T.3    Hughes, G.4
  • 8
    • 0030693995 scopus 로고    scopus 로고
    • Hormone replacement therapy in systemic lupus erythematosus
    • Kreidstein S, Urowitz M, Gladman D, Gough J. Hormone replacement therapy in systemic lupus erythematosus. J Rheumatol 1997;24:2149-52.
    • (1997) J Rheumatol , vol.24 , pp. 2149-2152
    • Kreidstein, S.1    Urowitz, M.2    Gladman, D.3    Gough, J.4
  • 9
    • 0031784298 scopus 로고    scopus 로고
    • Safety of hormonal replacement therapy in postmenopausal patients with systemic lupus erythematosus
    • Mok C, Lau C, Ho C, Lee K, Mok M, Wong R. Safety of hormonal replacement therapy in postmenopausal patients with systemic lupus erythematosus. Scand J Rheumatol 1998;27:342-6.
    • (1998) Scand J Rheumatol , vol.27 , pp. 342-346
    • Mok, C.1    Lau, C.2    Ho, C.3    Lee, K.4    Mok, M.5    Wong, R.6
  • 10
    • 20544443248 scopus 로고    scopus 로고
    • The effect of combined estrogen and progesterone hormone replacement therapy on disease activity in systemic lupus erythematosus: A randomized trial
    • Buyon J, Petri MA, Kim MY, Kalunian KC, Grossman J, Hahn BH, et al. The effect of combined estrogen and progesterone hormone replacement therapy on disease activity in systemic lupus erythematosus: a randomized trial. Ann Intern Med 2005;142:953-62.
    • (2005) Ann Intern Med , vol.142 , pp. 953-962
    • Buyon, J.1    Petri, M.A.2    Kim, M.Y.3    Kalunian, K.C.4    Grossman, J.5    Hahn, B.H.6
  • 11
    • 0021361006 scopus 로고
    • Effects of the oestrogen antagonist tamoxifen on disease indices in systemic lupus erythematosus
    • Sturgess A, Evans D, Mackay I, Riglar A. Effects of the oestrogen antagonist tamoxifen on disease indices in systemic lupus erythematosus. J Clin Lab Immunol 1984;13:11-4.
    • (1984) J Clin Lab Immunol , vol.13 , pp. 11-14
    • Sturgess, A.1    Evans, D.2    Mackay, I.3    Riglar, A.4
  • 12
    • 29144439823 scopus 로고    scopus 로고
    • Raloxifene for postmenopausal women with systemic lupus erythematosus: A pilot randomized controlled study
    • Mok C, To C, Mak A, Ma K. Raloxifene for postmenopausal women with systemic lupus erythematosus: a pilot randomized controlled study. Arthritis Rheum 2005;52:3997-4002.
    • (2005) Arthritis Rheum , vol.52 , pp. 3997-4002
    • Mok, C.1    To, C.2    Mak, A.3    Ma, K.4
  • 13
    • 0033305438 scopus 로고    scopus 로고
    • Estrogen receptor null mice: What have we learned and where will they lead us?
    • Couse J, Korach K. Estrogen receptor null mice: what have we learned and where will they lead us? Endocr Rev 1999;20:358-417.
    • (1999) Endocr Rev , vol.20 , pp. 358-417
    • Couse, J.1    Korach, K.2
  • 14
    • 0037204724 scopus 로고    scopus 로고
    • Connections and regulation of the human estrogen receptor
    • McDonnell D, Norris J. Connections and regulation of the human estrogen receptor. Science 2002;296:1642-4.
    • (2002) Science , vol.296 , pp. 1642-1644
    • McDonnell, D.1    Norris, J.2
  • 15
    • 34247169508 scopus 로고    scopus 로고
    • Effects of estrogen receptor subtype-selective agonists on autoimmune disease in lupus-prone NZB/NZW F1 mouse model
    • Li J, McMurray R. Effects of estrogen receptor subtype-selective agonists on autoimmune disease in lupus-prone NZB/NZW F1 mouse model. Clin Immunol 2007;123:219-26.
    • (2007) Clin Immunol , vol.123 , pp. 219-226
    • Li, J.1    McMurray, R.2
  • 16
    • 46949091514 scopus 로고    scopus 로고
    • Impact of estrogen receptor deficiency on disease expression in the NZM2410 lupus prone mouse
    • Svenson J, EuDaly J, Ruiz P, Korach K, Gilkeson G. Impact of estrogen receptor deficiency on disease expression in the NZM2410 lupus prone mouse. Clin Immunol 2008;128:259-68.
    • (2008) Clin Immunol , vol.128 , pp. 259-268
    • Svenson, J.1    EuDaly, J.2    Ruiz, P.3    Korach, K.4    Gilkeson, G.5
  • 18
    • 0033855713 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators: Structure, function, and clinical use
    • Osborne CK, Zhao H, Fuqua SA. Selective estrogen receptor modulators: structure, function, and clinical use. J Clin Oncol 2000;18:3172-86.
    • (2000) J Clin Oncol , vol.18 , pp. 3172-3186
    • Osborne, C.K.1    Zhao, H.2    Fuqua, S.A.3
  • 19
    • 0025343030 scopus 로고    scopus 로고
    • Effects of tamoxifen treatment on plasma lipids and lipoprotein lipid composition
    • 190
    • Bagdade J, Wolter J, Subbaiah P, Ryan W. Effects of tamoxifen treatment on plasma lipids and lipoprotein lipid composition. J Clin Endocrinol Metab 190;70:1132-5.
    • J Clin Endocrinol Metab , vol.70 , pp. 1132-1135
    • Bagdade, J.1    Wolter, J.2    Subbaiah, P.3    Ryan, W.4
  • 20
    • 67349093921 scopus 로고    scopus 로고
    • The effect of exemestane or tamoxifen on markers of bone turnover: Results of a German sub-study of the Tamoxifen Exemestane Adjuvant Multicentre (TEAM) trial
    • Hadji P, Ziller M, Kieback D, Menschik T, Kalder M, Kuck J, et al. The effect of exemestane or tamoxifen on markers of bone turnover: results of a German sub-study of the Tamoxifen Exemestane Adjuvant Multicentre (TEAM) trial. Breast 2009;18:159-64.
    • (2009) Breast , vol.18 , pp. 159-164
    • Hadji, P.1    Ziller, M.2    Kieback, D.3    Menschik, T.4    Kalder, M.5    Kuck, J.6
  • 22
    • 0034566068 scopus 로고    scopus 로고
    • Tamoxifen to prevent breast cancer
    • Morrow M, Jordan V. Tamoxifen to prevent breast cancer. Adv Surg 2000;34:287-99.
    • (2000) Adv Surg , vol.34 , pp. 287-299
    • Morrow, M.1    Jordan, V.2
  • 23
    • 0033575083 scopus 로고    scopus 로고
    • The effect of raloxifene on risk of breast cancer in postmenopausal women: Results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation
    • Cummings S, Eckert S, Krueger K, Grady D, Powles T, Cauley J, et al. The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation. JAMA 1999;281:2189-97.
    • (1999) JAMA , vol.281 , pp. 2189-2197
    • Cummings, S.1    Eckert, S.2    Krueger, K.3    Grady, D.4    Powles, T.5    Cauley, J.6
  • 24
    • 0033989737 scopus 로고    scopus 로고
    • Uterine effects of 3-year raloxifene therapy in postmenopausal women younger than age 60
    • Cohen F, Watts S, Shah A, Akers R, Plouffe L Jr. Uterine effects of 3-year raloxifene therapy in postmenopausal women younger than age 60. Obstet Gynecol 2000;95:104-10.
    • (2000) Obstet Gynecol , vol.95 , pp. 104-110
    • Cohen, F.1    Watts, S.2    Shah, A.3    Akers, R.4    Plouffe Jr., L.5
  • 25
    • 0034088850 scopus 로고    scopus 로고
    • Comparative effects of estrogen and raloxifene on B lymphopoiesis and bone loss induced by sex steroid deficiency in mice
    • Onoe Y, Miyaura C, Ito M, Ohta H, Nozawa S, Suda T. Comparative effects of estrogen and raloxifene on B lymphopoiesis and bone loss induced by sex steroid deficiency in mice. J Bone Miner Res 2000;15:541-9.
    • (2000) J Bone Miner Res , vol.15 , pp. 541-549
    • Onoe, Y.1    Miyaura, C.2    Ito, M.3    Ohta, H.4    Nozawa, S.5    Suda, T.6
  • 26
    • 0033826737 scopus 로고    scopus 로고
    • Tamoxifen decreases renal inflammation and alleviates disease severity in autoimmune NZB/W F1 mice
    • Wu W, Lin B, Su Y, Suen J, Chiang B. Tamoxifen decreases renal inflammation and alleviates disease severity in autoimmune NZB/W F1 mice. Scand J Immunol 2000;52:393-400.
    • (2000) Scand J Immunol , vol.52 , pp. 393-400
    • Wu, W.1    Lin, B.2    Su, Y.3    Suen, J.4    Chiang, B.5
  • 27
    • 0037378670 scopus 로고    scopus 로고
    • Beneficial effects of the anti-oestrogen tamoxifen on systemic lupus erythematosus of (NZBxNZW)F1 female mice are associated with specific reduction of IgG3 autoantibodies
    • Sthoeger Z, Zinger H, Mozes E. Beneficial effects of the anti-oestrogen tamoxifen on systemic lupus erythematosus of (NZBxNZW)F1 female mice are associated with specific reduction of IgG3 autoantibodies. Ann Rheum Dis 2003;62:341-6.
    • (2003) Ann Rheum Dis , vol.62 , pp. 341-346
    • Sthoeger, Z.1    Zinger, H.2    Mozes, E.3
  • 28
    • 22544466959 scopus 로고    scopus 로고
    • Tamoxifen blocks estrogen-induced B cell maturation but not survival
    • Peeva E, Venkatesh J, Diamond B. Tamoxifen blocks estrogen-induced B cell maturation but not survival. J Immunol 2005;175:1415-23.
    • (2005) J Immunol , vol.175 , pp. 1415-1423
    • Peeva, E.1    Venkatesh, J.2    Diamond, B.3
  • 29
    • 3042653655 scopus 로고    scopus 로고
    • Genotoxic mechanism of tamoxifen in developing endometrial cancer
    • Kim S, Suzuki N, Laxmi Y, Shibutani S. Genotoxic mechanism of tamoxifen in developing endometrial cancer. Drug Metab Rev 2004;36:199-218.
    • (2004) Drug Metab Rev , vol.36 , pp. 199-218
    • Kim, S.1    Suzuki, N.2    Laxmi, Y.3    Shibutani, S.4
  • 30
    • 13844293153 scopus 로고    scopus 로고
    • Raloxifene- and estradiol-mediated effects on uterus, bone and B lymphocytes in mice
    • Erlandsson M, Jonsson CA, Islander U, Ohlsson C, Carlsten H. Raloxifene- and estradiol-mediated effects on uterus, bone and B lymphocytes in mice. J Endocrinol 2002;175:319-27.
    • (2002) J Endocrinol , vol.175 , pp. 319-327
    • Erlandsson, M.1    Jonsson, C.A.2    Islander, U.3    Ohlsson, C.4    Carlsten, H.5
  • 31
    • 0031830892 scopus 로고    scopus 로고
    • The role of estrogen receptors and androgen receptors in sex steroid regulation of B lymphopoiesis
    • Smithson G, Couse J, Lubahn D, Korach K, Kincade P. The role of estrogen receptors and androgen receptors in sex steroid regulation of B lymphopoiesis. J Immunol 1998;161:27-34.
    • (1998) J Immunol , vol.161 , pp. 27-34
    • Smithson, G.1    Couse, J.2    Lubahn, D.3    Korach, K.4    Kincade, P.5
  • 32
    • 0034646432 scopus 로고    scopus 로고
    • Estrogen up-regulates Bcl-2 and blocks tolerance induction of naive B cells
    • Bynoe M, Grimaldi C, Diamond B. Estrogen up-regulates Bcl-2 and blocks tolerance induction of naive B cells. Proc Natl Acad Sci USA 2000;97:2703-8.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 2703-2708
    • Bynoe, M.1    Grimaldi, C.2    Diamond, B.3
  • 33
    • 0033660070 scopus 로고    scopus 로고
    • Bromocriptine restores tolerance in estrogen-treated mice
    • Peeva E, Grimaldi C, Spatz L, Diamond B. Bromocriptine restores tolerance in estrogen-treated mice. J Clin Invest 2000;106:1373-9.
    • (2000) J Clin Invest , vol.106 , pp. 1373-1379
    • Peeva, E.1    Grimaldi, C.2    Spatz, L.3    Diamond, B.4
  • 34
    • 0024100105 scopus 로고
    • Serial studies of the IgG subclass and functional affinity of DNA antibodies in systemic lupus erythematosus
    • Devey ME, Lee SR, Le Page S, Feldman R, Isenberg DA. Serial studies of the IgG subclass and functional affinity of DNA antibodies in systemic lupus erythematosus. J Autoimmun 1988;1:483-94.
    • (1988) J Autoimmun , vol.1 , pp. 483-494
    • Devey, M.E.1    Lee, S.R.2    Le Page, S.3    Feldman, R.4    Isenberg, D.A.5
  • 35
    • 0347988004 scopus 로고    scopus 로고
    • Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus
    • Zeng D, Liu Y, Sidobre S, Kronenberg M, Strober S. Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus. J Clin Invest 2003;112:1211-22.
    • (2003) J Clin Invest , vol.112 , pp. 1211-1222
    • Zeng, D.1    Liu, Y.2    Sidobre, S.3    Kronenberg, M.4    Strober, S.5
  • 36
    • 0025886306 scopus 로고
    • IgG3 production in MRL/lpr mice is responsible for development of lupus nephritis
    • Takahashi S, Nose M, Sasaki J, Yamamoto T, Kyogoku M. IgG3 production in MRL/lpr mice is responsible for development of lupus nephritis. J Immunol 1991;147:515-9.
    • (1991) J Immunol , vol.147 , pp. 515-519
    • Takahashi, S.1    Nose, M.2    Sasaki, J.3    Yamamoto, T.4    Kyogoku, M.5
  • 37
    • 0029003671 scopus 로고
    • Transitional B cells are the target of negative selection in the B cell compartment
    • Carsetti R, Köhler G, Lamers M. Transitional B cells are the target of negative selection in the B cell compartment. J Exp Med 1995;181:2129-40.
    • (1995) J Exp Med , vol.181 , pp. 2129-2140
    • Carsetti, R.1    Köhler, G.2    Lamers, M.3
  • 38
    • 4344597627 scopus 로고    scopus 로고
    • Mechanism of action of transmembrane activator and calcium modulator ligand interactor-Ig in murine systemic lupus erythematosus
    • Ramanujam M, Wang X, Huang W, Schiffer L, Grimaldi C, Akkerman A, et al. Mechanism of action of transmembrane activator and calcium modulator ligand interactor-Ig in murine systemic lupus erythematosus. J Immunol 2004;173:3524-34.
    • (2004) J Immunol , vol.173 , pp. 3524-3534
    • Ramanujam, M.1    Wang, X.2    Huang, W.3    Schiffer, L.4    Grimaldi, C.5    Akkerman, A.6
  • 39
    • 0035881589 scopus 로고    scopus 로고
    • Cutting edge: Expansion and activation of a population of autoreactive marginal zone B cells in a model of estrogen-induced lupus
    • Grimaldi C, Michael D, Diamond B. Cutting edge: expansion and activation of a population of autoreactive marginal zone B cells in a model of estrogen-induced lupus. J Immunol 2001;167:1886-90.
    • (2001) J Immunol , vol.167 , pp. 1886-1890
    • Grimaldi, C.1    Michael, D.2    Diamond, B.3
  • 41
    • 0033919320 scopus 로고    scopus 로고
    • B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a "natural immune memory"
    • Martin F, Kearney J. B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a "natural immune memory". Immunol Rev 2000;175:70-9.
    • (2000) Immunol Rev , vol.175 , pp. 70-79
    • Martin, F.1    Kearney, J.2
  • 44
    • 0033583479 scopus 로고    scopus 로고
    • Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies
    • O'Keefe T, Williams G, Batista F, Neuberger M. Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies. J Exp Med 1999;189:1307-13.
    • (1999) J Exp Med , vol.189 , pp. 1307-1313
    • O'Keefe, T.1    Williams, G.2    Batista, F.3    Neuberger, M.4
  • 45
    • 0034139373 scopus 로고    scopus 로고
    • T cells in the pathogenesis of systemic lupus erythematosus: Potential roles of CD154-CD40 interactions and costimulatory molecules
    • Yellin M, Thienel U. T cells in the pathogenesis of systemic lupus erythematosus: potential roles of CD154-CD40 interactions and costimulatory molecules. Curr Rheumatol Rep 2000;2:24-31.
    • (2000) Curr Rheumatol Rep , vol.2 , pp. 24-31
    • Yellin, M.1    Thienel, U.2
  • 46
    • 0032416375 scopus 로고    scopus 로고
    • Production of pathogenic antibodies: Cognate interactions between autoimmune T and B cells
    • Datta S. Production of pathogenic antibodies: cognate interactions between autoimmune T and B cells. Lupus 1998;7:591-6.
    • (1998) Lupus , vol.7 , pp. 591-596
    • Datta, S.1
  • 47
    • 0014259755 scopus 로고
    • Pathogenesis of the glomerulonephritis of NZB/W mice
    • Lambert P, Dixon F. Pathogenesis of the glomerulonephritis of NZB/W mice. J Exp Med 1968;127:507-22.
    • (1968) J Exp Med , vol.127 , pp. 507-522
    • Lambert, P.1    Dixon, F.2
  • 49
    • 0034654329 scopus 로고    scopus 로고
    • Estrogen influences the differentiation, proliferation, and survival of early B-lineage precursors
    • Medina KL, Strasser A, Kincade PW. Estrogen influences the differentiation, proliferation, and survival of early B-lineage precursors. Blood 2000;95:2059-67.
    • (2000) Blood , vol.95 , pp. 2059-2067
    • Medina, K.L.1    Strasser, A.2    Kincade, P.W.3
  • 50
    • 0027937803 scopus 로고
    • Estrogen induces suppression of natural killer cell cytotoxicity and augmentation of polyclonal B cell activation
    • Nilsson N, Carlsten H. Estrogen induces suppression of natural killer cell cytotoxicity and augmentation of polyclonal B cell activation. Cell Immunol 1994;158:131-9.
    • (1994) Cell Immunol , vol.158 , pp. 131-139
    • Nilsson, N.1    Carlsten, H.2
  • 51
    • 0027359538 scopus 로고
    • Histocompatibility complex gene products and exposure to oestrogen: Two independent disease accelerating factors in murine lupus
    • Carlsten H, Tarkowski A. Histocompatibility complex gene products and exposure to oestrogen: two independent disease accelerating factors in murine lupus. Scand J Immunol 1993;38:341-7.
    • (1993) Scand J Immunol , vol.38 , pp. 341-347
    • Carlsten, H.1    Tarkowski, A.2
  • 52
    • 0027254774 scopus 로고
    • Antibodies to cardiolipin in normal C57BL/6J mice: Induction by estrogen but not dihydrotestosterone
    • Ahmed S, Verthelyi D. Antibodies to cardiolipin in normal C57BL/6J mice: induction by estrogen but not dihydrotestosterone. J Autoimmun 1993;6:265-79.
    • (1993) J Autoimmun , vol.6 , pp. 265-279
    • Ahmed, S.1    Verthelyi, D.2
  • 53
    • 33644505807 scopus 로고    scopus 로고
    • Hormonal regulation of B cell development: 17 beta-estradiol impairs negative selection of high-affinity DNA-reactive B cells at more than one developmental checkpoint
    • Grimaldi CM, Jeganathan V, Diamond B. Hormonal regulation of B cell development: 17 beta-estradiol impairs negative selection of high-affinity DNA-reactive B cells at more than one developmental checkpoint. J Immunol 2006;176:2703-10.
    • (2006) J Immunol , vol.176 , pp. 2703-2710
    • Grimaldi, C.M.1    Jeganathan, V.2    Diamond, B.3
  • 54
  • 57
    • 33645317399 scopus 로고    scopus 로고
    • Raloxifene reduces fractures in postmenopausal women with osteoporosis
    • Reginster JY, Devogelaer JP. Raloxifene reduces fractures in postmenopausal women with osteoporosis. Clin Orthop Relat Res 2006;443:48-54.
    • (2006) Clin Orthop Relat Res , vol.443 , pp. 48-54
    • Reginster, J.Y.1    Devogelaer, J.P.2
  • 58
    • 0028061884 scopus 로고
    • Raloxifene preserves bone strength and bone mass in ovariectomized rats
    • Turner CH, Sato M, Bryant HU. Raloxifene preserves bone strength and bone mass in ovariectomized rats. Endocrinology 1994;135:2001-5.
    • (1994) Endocrinology , vol.135 , pp. 2001-2005
    • Turner, C.H.1    Sato, M.2    Bryant, H.U.3
  • 60
    • 0028287647 scopus 로고
    • Effects of tamoxifen on uterus and ovaries of postmenopausal women in a randomized breast cancer prevention trial
    • Black L, Keder R, Bourne T, Powles T, Collins W, Ashley S, et al. Effects of tamoxifen on uterus and ovaries of postmenopausal women in a randomized breast cancer prevention trial. Lancet 1994;343:1318-21.
    • (1994) Lancet , vol.343 , pp. 1318-1321
    • Black, L.1    Keder, R.2    Bourne, T.3    Powles, T.4    Collins, W.5    Ashley, S.6
  • 61
    • 23444439510 scopus 로고    scopus 로고
    • The selective estrogen receptor modulators, tamoxifen and raloxifene, impair dendritic cell differentiation and activation
    • Nalbandian G, Paharkova-Vatchkova V, Mao A, Nale S, Kovats S. The selective estrogen receptor modulators, tamoxifen and raloxifene, impair dendritic cell differentiation and activation. J Immunol 2005;175:2666-75.
    • (2005) J Immunol , vol.175 , pp. 2666-2675
    • Nalbandian, G.1    Paharkova-Vatchkova, V.2    Mao, A.3    Nale, S.4    Kovats, S.5
  • 62
  • 63
    • 0025113699 scopus 로고
    • Anti-oestrogens induce the secretion of active transforming growth factor beta from human fetal fibroblasts
    • Colletta A, Wakefield L, Howell F, van Roozendaal K, Danielpour D, Ebbs S, et al. Anti-oestrogens induce the secretion of active transforming growth factor beta from human fetal fibroblasts. Br J Cancer 1990;62:405-9.
    • (1990) Br J Cancer , vol.62 , pp. 405-409
    • Colletta, A.1    Wakefield, L.2    Howell, F.3    Van Roozendaal, K.4    Danielpour, D.5    Ebbs, S.6
  • 64
    • 0031031550 scopus 로고    scopus 로고
    • The beneficial effects of treatment with tamoxifen and anti-oestradiol antibody on experimental systemic lupus erythematosus are associated with cytokine modulations
    • Dayan M, Zinger H, Kalush F, Mor G, Amir-Zaltzman Y, Kohen F, et al. The beneficial effects of treatment with tamoxifen and anti-oestradiol antibody on experimental systemic lupus erythematosus are associated with cytokine modulations. Immunology 1997;90:101-8.
    • (1997) Immunology , vol.90 , pp. 101-108
    • Dayan, M.1    Zinger, H.2    Kalush, F.3    Mor, G.4    Amir-Zaltzman, Y.5    Kohen, F.6
  • 65
    • 0034053286 scopus 로고    scopus 로고
    • Tamoxifen alleviates disease severity and decreases double negative T cells in autoimmune MRL-lpr/lpr mice
    • Wu W, Suen J, Lin B, Chiang B. Tamoxifen alleviates disease severity and decreases double negative T cells in autoimmune MRL-lpr/lpr mice. Immunology 2000;100:110-8.
    • (2000) Immunology , vol.100 , pp. 110-118
    • Wu, W.1    Suen, J.2    Lin, B.3    Chiang, B.4
  • 66
    • 34247178424 scopus 로고    scopus 로고
    • Renoprotective effects of a selective estrogen receptor modulator, raloxifene, in an animal model of diabetic nephropathy
    • Dixon A, Wells C, Singh S, Babayan R, Maric C. Renoprotective effects of a selective estrogen receptor modulator, raloxifene, in an animal model of diabetic nephropathy. Am J Nephrol 2007;27:120-8.
    • (2007) Am J Nephrol , vol.27 , pp. 120-128
    • Dixon, A.1    Wells, C.2    Singh, S.3    Babayan, R.4    Maric, C.5
  • 67
  • 68
    • 0030267659 scopus 로고    scopus 로고
    • Anti-CD40 ligand antibody treatment prevents the development of lupus-like nephritis in a subset of New Zealand black x New Zealand white mice. Response correlates with the absence of an anti-antibody response
    • Early G, Zhao W, Burns C. Anti-CD40 ligand antibody treatment prevents the development of lupus-like nephritis in a subset of New Zealand black x New Zealand white mice. Response correlates with the absence of an anti-antibody response. J Immunol 1996;157:3159-64.
    • (1996) J Immunol , vol.157 , pp. 3159-3164
    • Early, G.1    Zhao, W.2    Burns, C.3
  • 69
    • 0036272915 scopus 로고    scopus 로고
    • The effect of anti-CD40 ligand antibody on B cells in human systemic lupus erythematosus
    • Huang W, Sinha J, Newman J, Reddy B, Budhai L, Furie R, et al. The effect of anti-CD40 ligand antibody on B cells in human systemic lupus erythematosus. Arthritis Rheum 2002;46:1554-62.
    • (2002) Arthritis Rheum , vol.46 , pp. 1554-1562
    • Huang, W.1    Sinha, J.2    Newman, J.3    Reddy, B.4    Budhai, L.5    Furie, R.6
  • 70
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors a and b
    • Kuiper G, Carlsson B, Grandien K, Enmark E, Haggblad J, Nilsson S, et al. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors a and b. Endocrinology 1997;138:863-70.
    • (1997) Endocrinology , vol.138 , pp. 863-870
    • Kuiper, G.1    Carlsson, B.2    Grandien, K.3    Enmark, E.4    Haggblad, J.5    Nilsson, S.6
  • 71
    • 73349083946 scopus 로고    scopus 로고
    • The induction of the lupus phenotype by estrogen is via an estrogen receptor-alpha-dependent pathway
    • Epub 2009 Nov 17
    • Feng F, Nyland J, Banyai M, Tatum A, Silverstone A, Gavalchin J. The induction of the lupus phenotype by estrogen is via an estrogen receptor-alpha-dependent pathway. Clin Immunol 2010;134:226-36. Epub 2009 Nov 17.
    • (2010) Clin Immunol , vol.134 , pp. 226-236
    • Feng, F.1    Nyland, J.2    Banyai, M.3    Tatum, A.4    Silverstone, A.5    Gavalchin, J.6
  • 72
    • 0030801841 scopus 로고    scopus 로고
    • Differential ligand activation of estrogen receptors ERα and ERß at AP1 sites
    • Paech K, Webb P, Kuiper G, Nilsson S, Gustafsson J, Kushner P, et al. Differential ligand activation of estrogen receptors ERα and ERß at AP1 sites. Science 1997;277:1508-10.
    • (1997) Science , vol.277 , pp. 1508-1510
    • Paech, K.1    Webb, P.2    Kuiper, G.3    Nilsson, S.4    Gustafsson, J.5    Kushner, P.6
  • 73
    • 1642332240 scopus 로고    scopus 로고
    • Estrogen signaling: A subtle balance between ER α and ER ß
    • Matthews J, Gustafsson J. Estrogen signaling: a subtle balance between ER α and ER ß. Mol Interv 2003;3:281-92.
    • (2003) Mol Interv , vol.3 , pp. 281-292
    • Matthews, J.1    Gustafsson, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.