The induction of the lupus phenotype by estrogen is via an estrogen receptor-α-dependent pathway

Clinical Immunology

Volumn 134, Issue 2, 2010, Pages 226-236

  Feng, Feng ^a   Nyland, Jennifer ^b   Banyai, Michelle ^a   Tatum, Arthur ^c   Silverstone, Allen E ^b   Gavalchin, Jerrie ^a,b  

^a Department of Obstetrics Gynecology   (United States)

^b State University of New York Upstate Medical University: College of Medicine   (United States)

^c SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

Author keywords

ER deficient mouse; Estradiol; Estrogen receptor; Idiotypic reactive T cells; Lupus

Indexed keywords

AUTOANTIBODY; DNA ANTIBODY; DOUBLE STRANDED DNA ANTIBODY; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GAMMA INTERFERON; IDLNF 1 ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; SINGLE STRANDED DEOXYRIBONUCLEIC ACID ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; BODY WEIGHT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEATH; DENDRITIC CELL; FEMALE; IMMUNOCOMPETENT CELL; KIDNEY INJURY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SURVIVAL; SYSTEMIC LUPUS ERYTHEMATOSUS; TH2 CELL; WILD TYPE;

ANIMALS; AUTOANTIBODIES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL SEPARATION; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGENS; FLOW CYTOMETRY; LUPUS ERYTHEMATOSUS, SYSTEMIC; LUPUS NEPHRITIS; MICE; MICE, KNOCKOUT; PHENOTYPE;

EID: 73349083946     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2009.10.004     Document Type: Article

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