Deficiency in B7-H1 (PD-L1)/PD-1 coinhibition triggers pancreatic β-cell destruction by insulin-specific, murine CD8 T-cells

Diabetes

Volumn 59, Issue 8, 2010, Pages 1966-1973

  Rajasalu, Tarvo ^a,b   Brosi, Helen ^a   Schuster, Cornelia ^a   Spyrantis, Andreas ^a   Boehm, Bernhard Otto ^a   Chen, Lieping ^c   Reimann, Jörg ^a   Schirmbeck, Reinhold ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b UNIVERSITY OF TARTU   (Estonia)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; GLUCOSE; INSULIN;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNITY; CD8+ T LYMPHOCYTE; CELL DESTRUCTION; CONGENIC STRAIN; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GLUCOSE BLOOD LEVEL; IMMUNIZATION; IMMUNOMODULATION; IMMUNOPATHOGENESIS; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN DEFICIENCY;

ANIMALS; ANTIGENS, CD80; CD8-POSITIVE T-LYMPHOCYTES; DIABETES MELLITUS, TYPE 1; HUMANS; INSULIN; INSULIN-SECRETING CELLS; INTERFERON-GAMMA; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PEPTIDES; PROTEIN PRECURSORS;

EID: 77955359941     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db09-1135     Document Type: Article

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