Paradoxical role of prion protein aggregates in redox-lron induced toxicity

PLoS ONE

Volumn 5, Issue 7, 2010, Pages

  Das, Dola ^a   Luo, Xiu ^a   Singh, Ajay ^a   Gu, Yaping ^a   Ghosh, Soumya ^a   Mukhopadhyay, Chinmay K ^b   Chen, Shu G ^a   Sy, Man Sun ^a   Kong, Qingzhong ^a   Singh, Neena ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; FERRIC AMMONIUM CITRATE; FERRITIN; HYDROGEN PEROXIDE; IRON; MUTANT PROTEIN; PRION PROTEIN; PROTEIN LC3 II; UNCLASSIFIED DRUG; FERRIC ION; QUATERNARY AMMONIUM DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; AUTOPHAGY; CELL CULTURE; CELL LINE; CELL MUTANT; CELL PROTECTION; CELL TYPE; CELL VIABILITY; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; DISEASE ASSOCIATION; HAMSTER; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NEUROTOXICITY; NONHUMAN; PHAGOCYTOSIS; PHENOTYPE; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REDOX STRESS; CULTURE MEDIUM; DRUG EFFECT; ELECTRON MICROSCOPY; IMMUNOPRECIPITATION; LYSOSOME; METABOLISM; PHAGOSOME; PRION; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALIA; CRICETINAE;

ASTROCYTES; BLOTTING, WESTERN; CELL LINE, TUMOR; CULTURE MEDIA, CONDITIONED; FERRIC COMPOUNDS; FERRITINS; HUMANS; HYDROGEN PEROXIDE; IMMUNOPRECIPITATION; LYSOSOMES; MICROSCOPY, ELECTRON; PHAGOCYTOSIS; PHAGOSOMES; PRIONS; QUATERNARY AMMONIUM COMPOUNDS;

EID: 77955348149     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011420     Document Type: Article

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