DNAJB6 induces degradation of β-catenin and causes partial reversal of mesenchymal phenotype

Journal of Biological Chemistry

Volumn 285, Issue 32, 2010, Pages 24686-24694

  Mitra, Aparna ^a   Menezes, Mitchell E ^a   Shevde, Lalita A ^a   Samant, Rajeev S ^a  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEGRADATION;

BREAST CANCER; CANCER CELLS; CATENIN SIGNALING; DOWN-REGULATION; DUCTAL CARCINOMA; EPITHELIAL-MESENCHYMAL TRANSITION; IN-CELL; MELANOMA CELLS; POTENTIAL MECHANISM; SIGNALING PATHWAYS; UP-REGULATION; VIMENTIN; WNT PATHWAY;

SIGNALING;

BETA CATENIN; CYTOKERATIN 18; DICKKOPF 1 PROTEIN; DNAJB6 PROTEIN; HEAT SHOCK PROTEIN 40; NERVE CELL ADHESION MOLECULE; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR TWIST; UNCLASSIFIED DRUG; VIMENTIN; WNT PROTEIN; CHAPERONE; DKK1 PROTEIN, HUMAN; DNAJB6 PROTEIN, HUMAN; NERVE PROTEIN; PROTEASOME; SIGNAL PEPTIDE;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL STRUCTURE; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; MESENCHYME; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; UPREGULATION; BIOLOGICAL MODEL; CELL MOTION; GENE EXPRESSION REGULATION; MESODERM; METABOLISM; METASTASIS; WOUND HEALING;

BETA CATENIN; CELL MOVEMENT; GENE EXPRESSION REGULATION, NEOPLASTIC; HSP40 HEAT-SHOCK PROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MESODERM; MODELS, BIOLOGICAL; MOLECULAR CHAPERONES; NEOPLASM METASTASIS; NERVE TISSUE PROTEINS; PHENOTYPE; PROTEASOME ENDOPEPTIDASE COMPLEX; WNT PROTEINS; WOUND HEALING;

EID: 77955287732     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.094847     Document Type: Article

References (76)

1. Ohtsuka, K., and Hata, M. (2000) Cell Stress Chaperones 5, 98-112
2. Deleted in proof
3. Tsai, M. F., Wang, C. C., Chang, G. C., Chen, C. Y., Chen, H. Y., Cheng, C. L., Yang, Y. P., Wu, C. Y., Shih, F. Y., Liu, C. C., Lin, H. P., Jou, Y. S., Lin, S. C., Lin, C. W., Chen, W. J., Chan, W. K., Chen, J. J., and Yang, P. C. (2006) J. Natl. Cancer Inst. 98, 825-838
4. Chen, H. W., Lee, J. Y., Huang, J. Y., Wang, C. C., Chen, W. J., Su, S. F., Huang, C. W., Ho, C. C., Chen, J. J., Tsai, M. F., Yu, S. L., and Yang, P. C. (2008) Cancer Res. 68, 7428-7438
5. Wang, C. C., Tsai, M. F., Dai, T. H., Hong, T. M., Chan, W. K., Chen, J. J., and Yang, P. C. (2007) Cancer Res. 67, 4816-4826
6. Cheng, H., Cenciarelli, C., Nelkin, G., Tsan, R., Fan, D., Cheng-Mayer, C., and Fidler, I. J. (2005) Mol. Cell. Biol. 25, 44-59
7. Mitra, A., Fillmore, R. A., Metge, B. J., Rajesh, M., Xi, Y., King, J., Ju, J., Pannell, L., Shevde, L. A., and Samant, R. S. (2008) Breast Cancer Res. 10, R22
8. Dai, Y. S., Xu, J., and Molkentin, J. D. (2005) Mol. Cell. Biol. 25, 9936-9948
9. Izawa, I., Nishizawa, M., Ohtakara, K., Ohtsuka, K., Inada, H., and Inagaki, M. (2000) J. Biol. Chem. 275, 34521-34527
10. Chuang, J. Z., Zhou, H., Zhu, M., Li, S. H., Li, X. J., and Sung, C. H. (2002) J. Biol. Chem. 277, 19831-19838
11. Cheng, X., Belshan, M., and Ratner, L. (2008) J. Virol. 82, 1229-1237
12. Abba, M. C., Drake, J. A., Hawkins, K. A., Hu, Y., Sun, H., Notcovich, C., Gaddis, S., Sahin, A., Baggerly, K., and Aldaz, C. M. (2004) Breast Cancer Res. 6, R499-R513
13. Rae, J. M., Creighton, C. J., Meck, J. M., Haddad, B. R., and Johnson, M. D. (2007) Breast Cancer Res. Treat. 104, 13-19
14. Rae, J. M., Ramus, S. J., Waltham, M., Armes, J. E., Campbell, I. G., Clarke, R., Barndt, R. J., Johnson, M. D., and Thompson, E. W. (2004) Clin. Exp. Metastasis 21, 543-552
15. Xie, X., Brünner, N., Jensen, G., Albrectsen, J., Gotthardsen, B., and Rygaard, J. (1992) Clin. Exp. Metastasis 10, 201-210
16. Chambers, A. F. (2009) Cancer Res. 69, 5292-5293
17. Strickland, L. B., Dawson, P. J., Santner, S. J., and Miller, F. R. (2000) Breast Cancer Res. Treat. 64, 235-240
18. Santner, S. J., Dawson, P. J., Tait, L., Soule, H. D., Eliason, J., Mohamed, A. N., Wolman, S. R., Heppner, G. H., and Miller, F. R. (2001) Breast Cancer Res. Treat. 65, 101-110
19. Tait, L. R., Pauley, R. J., Santner, S. J., Heppner, G. H., Heng, H. H., Rak, J. W., and Miller, F. R. (2007) Int. J. Cancer 120, 2127-2134
20. Miller, F. R., Santner, S. J., Tait, L., and Dawson, P. J. (2000) J. Natl. Cancer Inst. 92, 1185-1186
21. Chamorro, M. N., Schwartz, D. R., Vonica, A., Brivanlou, A. H., Cho, K. R., and Varmus, H. E. (2005) EMBO J. 24, 73-84
22. Veeman, M. T., Slusarski, D. C., Kaykas, A., Louie, S. H., and Moon, R. T. (2003) Curr. Biol. 13, 680-685
23. Shevde, L. A., Samant, R. S., Paik, J. C., Metge, B. J., Chambers, A. F., Casey, G., Frost, A. R., and Welch, D. R. (2006) Clin. Exp. Metastasis 23, 123-133
24. Mironchik, Y., Winnard, P. T., Jr., Vesuna, F., Kato, Y., Wildes, F., Pathak, A. P., Kominsky, S., Artemov, D., Bhujwalla, Z., Van Diest, P., Burger, H., Glackin, C., and Raman, V. (2005) Cancer Res. 65, 10801-10809
25. Sarrió, D., Rodriguez-Pinilla, S. M., Hardisson, D., Cano, A., Moreno-Bueno, G., and Palacios, J. (2008) Cancer Res. 68, 989-997
26. Rylander, M. N., Feng, Y., Bass, J., and Diller, K. R. (2005) Ann. N.Y. Acad. Sci. 1066, 222-242
27. Schafer, C., and Williams, J. A. (2000) J. Gastroenterol. 35, 1-9
28. Pirkkala, L., Nykänen, P., and Sistonen, L. (2001) FASEB J. 15, 1118-1131
29. Jäättelä, M. (1999) Ann. Med. 31, 261-271
30. Matijasevic, Z., Snyder, J. E., and Ludlum, D. B. (1998) Oncol. Res. 10, 605-610
31. Sonna, L. A., Fujita, J., Gaffin, S. L., and Lilly, C. M. (2002) J. Appl. Physiol. 92, 1725-1742
32. Sõti, C., Nagy, E., Giricz, Z., Vígh, L., Csermely, P., and Ferdinandy, P. (2005) Br. J. Pharmacol. 146, 769-780
33. Georgakis, G. V., and Younes, A. (2005) Future Oncol. 1, 273-281
34. Wegele, H., Müller, L., and Buchner, J. (2004) Rev. Physiol. Biochem. Pharmacol. 151, 1-44
35. Didelot, C., Lanneau, D., Brunet, M., Joly, A. L., De Thonel, A., Chiosis, G., and Garrido, C. (2007) Curr. Med. Chem. 14, 2839-2847
36. Neckers, L. (2007) J. Biosci. 32, 517-530
37. Syken, J., De-Medina, T., and Münger, K. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 8499-8504
38. Kim, S. W., Chao, T. H., Xiang, R., Lo, J. F., Campbell, M. J., Fearns, C., and Lee, J. D. (2004) Cancer Res. 64, 7732-7739
39. Trentin, G. A., He, Y., Wu, D. C., Tang, D., and Rozakis-Adcock, M. (2004) FEBS Lett. 578, 323-330
40. Kim, S. W., Hayashi, M., Lo, J. F., Fearns, C., Xiang, R., Lazennec, G., Yang, Y., and Lee, J. D. (2005) Cancer Res. 65, 8784-8791
41. Syken, J., Macian, F., Agarwal, S., Rao, A., and Münger, K. (2003) Oncogene 22, 4636-4641
42. Wang, C. C., Tsai, M. F., Hong, T. M., Chang, G. C., Chen, C. Y., Yang, W. M., Chen, J. J., and Yang, P. C. (2005) Oncogene 24, 4081-4093
43. Mattila, P. K., and Lappalainen, P. (2008) Nat. Rev. Mol. Cell Biol. 9, 446-454
44. Azios, N. G., Krishnamoorthy, L., Harris, M., Cubano, L. A., Cammer, M., and Dharmawardhane, S. F. (2007) Neoplasia 9, 147-158
45. Vasioukhin, V., Bauer, C., Yin, M., and Fuchs, E. (2000) Cell 100, 209-219
46. Nieman, M. T., Prudoff, R. S., Johnson, K. R., and Wheelock, M. J. (1999) J. Cell Biol. 147, 631-644
47. Tsuruta, D., and Jones, J. C. (2003) J. Cell Sci. 116, 4977-4984
48. McInroy, L., and Määttä, A. (2007) Biochem. Biophys. Res. Commun. 360, 109-114
49. Bühler, H., and Schaller, G. (2005) Mol. Cancer Res. 3, 365-371
50. Korpal, M., Lee, E. S., Hu, G., and Kang, Y. (2008) J. Biol. Chem. 283, 14910-14914
51. Li, Y., VandenBoom, T. G., 2nd, Kong, D., Wang, Z., Ali, S., Philip, P. A., and Sarkar, F. H. (2009) Cancer Res. 69, 6704-6712
52. Gregory, P. A., Bert, A. G., Paterson, E. L., Barry, S. C., Tsykin, A., Farshid, G., Vadas, M. A., Khew-Goodall, Y., and Goodall, G. J. (2008) Nat. Cell Biol. 10, 593-601
53. Park, S. M., Gaur, A. B., Lengyel, E., and Peter, M. E. (2008) Genes Dev. 22, 894-907
54. Zavadil, J., Haley, J., Kalluri, R., Muthuswamy, S. K., and Thompson, E. (2008) Cancer Res. 68, 9574-9577
55. Klymkowsky, M. W., and Savagner, P. (2009) Am. J. Pathol. 174, 1588-1593
56. Jo, M., Lester, R. D., Montel, V., Eastman, B., Takimoto, S., and Gonias, S. L. (2009) J. Biol. Chem. 284, 22825-22833
57. Lester, R. D., Jo, M., Montel, V., Takimoto, S., and Gonias, S. L. (2007) J. Cell Biol. 178, 425-436
58. Larue, L., and Bellacosa, A. (2005) Oncogene 24, 7443-7454
59. Kalluri, R., and Weinberg, R. A. (2009) J. Clin. Invest. 119, 1420-1428
60. Kalluri, R., and Neilson, E. G. (2003) J. Clin. Invest. 112, 1776-1784
61. Huber, M. A., Kraut, N., and Beug, H. (2005) Curr. Opin. Cell Biol. 17, 548-558
62. Jiang, Y. G., Luo, Y., He, D. L., Li, X., Zhang, L. L., Peng, T., Li, M. C., and Lin, Y. H. (2007) Int. J. Urol. 14, 1034-1039
63. Schmalhofer, O., Brabletz, S., and Brabletz, T. (2009) Cancer Metastasis Rev. 28, 151-166
64. Kawano, Y., and Kypta, R. (2003) J. Cell Sci. 116, 2627-2634
65. Moon, R. T., Brown, J. D., Yang-Snyder, J. A., and Miller, J. R. (1997) Cell 88, 725-728
66. Suzuki, H., Toyota, M., Carraway, H., Caraway, H., Gabrielson, E., Ohmura, T., Fujikane, T., Nishikawa, N., Sogabe, Y., Nojima, M., Sonoda, T., Mori, M., Hirata, K., Imai, K., Shinomura, Y., Baylin, S. B., and Tokino, T. (2008) Br. J. Cancer 98, 1147-1156
67. Fillmore, R. A., Mitra, A., Xi, Y., Ju, J., Scammell, J., Shevde, L. A., and Samant, R. S. (2009) Int. J. Cancer 125, 556-564
68. Cowling, V. H., and Cole, M. D. (2007) Cell Cycle 6, 2625-2627
69. Cowling, V. H., D'Cruz, C. M., Chodosh, L. A., and Cole, M. D. (2007) Mol. Cell. Biol. 27, 5135-5146
70. DiMeo, T. A., Anderson, K., Phadke, P., Fan, C., Feng, C., Perou, C. M., Naber, S., and Kuperwasser, C. (2009) Cancer Res. 69, 5364-5373
71. Mikheev, A. M., Mikheeva, S. A., Maxwell, J. P., Rivo, J. V., Rostomily, R., Swisshelm, K., and Zarbl, H. (2008) Breast Cancer Res. Treat. 112, 263-273
72. Bafico, A., Liu, G., Goldin, L., Harris, V., and Aaronson, S. A. (2004) Cancer Cell 6, 497-506
73. Prasad, C. P., Gupta, S. D., Rath, G., and Ralhan, R. (2007) Oncology 73, 112-117
74. Hatsell, S., Rowlands, T., Hiremath, M., and Cowin, P. (2003) J. Mammary Gland Biol. Neoplasia 8, 145-158
75. Miyoshi, K., Rosner, A., Nozawa, M., Byrd, C., Morgan, F., Landesman-Bollag, E., Xu, X., Seldin, D. C., Schmidt, E. V., Taketo, M. M., Robinson, G. W., Cardiff, R. D., and Hennighausen, L. (2002) Oncogene 21, 5548-5556
76. Dissanayake, S. K., Wade, M., Johnson, C. E., O'Connell, M. P., Leotlela, P. D., French, A. D., Shah, K. V., Hewitt, K. J., Rosenthal, D. T., Indig, F. E., Jiang, Y., Nickoloff, B. J., Taub, D. D., Trent, J. M., Moon, R. T., Bittner, M., and Weeraratna, A. T. (2007) J. Biol. Chem. 282, 17259-17271