Secretion of SDF-1α by bone marrow-derived stromal cells enhances skin wound healing of C57BL/6 mice exposed to ionizing radiation

Journal of Cellular and Molecular Medicine

Volumn 14, Issue 6 B, 2010, Pages 1594-1604

  Landry, Yannick ^a   Lê, Oanh ^a   Mace, Kimberly A ^b   Restivo, Terry E ^c   Beauséjour, Christian M ^a  

^a UNIVERSITY OF MONTREAL   (Canada)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Ionizing radiation; Microenvironment; MSCs; SDF 1 ; Tissue regeneration

Indexed keywords

MUS;

STROMAL CELL DERIVED FACTOR 1;

ANGIOGENESIS; ANIMAL; ARTICLE; BONE MARROW CELL; C57BL MOUSE; CYTOLOGY; FEMALE; IONIZING RADIATION; MOUSE; MULTIPOTENT STEM CELL; PATHOLOGY; RADIATION EXPOSURE; SECRETION; SKIN; STROMA CELL; TIME; TRANSPLANTATION; WOUND HEALING;

ANIMALS; BONE MARROW CELLS; CHEMOKINE CXCL12; FEMALE; MICE; MICE, INBRED C57BL; MULTIPOTENT STEM CELLS; NEOVASCULARIZATION, PHYSIOLOGIC; RADIATION, IONIZING; SKIN; STROMAL CELLS; TIME FACTORS; WOUND HEALING;

EID: 77955161273     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2009.00887.x     Document Type: Article

References (46)

1. Geenen MM, Cardous-Ubbink MC, Kremer LC. Medical assessment of adverse health outcomes in long-term survivors of childhood cancer. JAMA. 2007, 297:2705-15.
2. Oeffinger KC, Mertens AC, Sklar CA. Chronic health conditions in adult survivors of childhood cancer. N Engl J Med. 2006, 355:1572-82.
3. Bujko K, Suit HD, Springfield DS, Convery K. Wound healing after preoperative radiation for sarcoma of soft tissues. Surg Gynecol Obstet. 1993, 176:124-34.
4. O'Sullivan B, Davis AM, Turcotte R. Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial. Lancet. 2002, 359:2235-41.
5. Werner S, Grose R. Regulation of wound healing by growth factors and cytokines. Physiol Rev. 2003, 83:835-70.
6. Galiano RD, Tepper OM, Pelo CR. Topical vascular endothelial growth factor accelerates diabetic wound healing through increased angiogenesis and by mobilizing and recruiting bone marrow-derived cells. Am J Pathol. 2004, 164:1935-47.
7. Asai J, Takenaka H, Kusano KF. Topical sonic hedgehog gene therapy accelerates wound healing in diabetes by enhancing endothelial progenitor cell-mediated microvascular remodeling. Circulation. 2006, 113:2413-24.
8. Badillo AT, Chung S, Zhang L. Lentiviral gene transfer of SDF-1alpha to wounds improves diabetic wound healing. J Surg Res. 2007, 143:35-42.
9. Galotto M, Berisso G, Delfino L. Stromal damage as consequence of high-dose chemo/radiotherapy in bone marrow transplant recipients. Exp Hematol. 1999, 27:1460-6.
10. Paterson MC, Sell BM, Smith BP. Impaired colony-forming ability following gamma irradiation of skin fibroblasts from tuberous sclerosis patients. Radiat Res. 1982, 90:260-70.
11. Hill RP, Kaspler P, Griffin AM. Studies of the in vivo radiosensitivity of human skin fibroblasts. Radiother Oncol. 2007, 84:75-83.
12. Piersma AH, Brockbank KG, Ploemacher RE. Recovery of hemopoietic stromal progenitor cells after lethal total-body irradiation and bone marrow transplantation in mice. Transplantation. 1985, 40:198-201.
13. Rombouts WJ, Ploemacher RE. Primary murine MSC show highly efficient homing to the bone marrow but lose homing ability following culture. Leukemia. 2003, 17:160-70.
14. Sasaki M, Abe R, Fujita Y. Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type. J Immunol. 2008, 180:2581-7.
15. Wu Y, Chen L, Scott PG. Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis. Stem Cells. 2007, 25:2648-59.
16. Badillo AT, Redden RA, Zhang L. Treatment of diabetic wounds with fetal murine mesenchymal stromal cells enhances wound closure. Cell Tissue Res. 2007, 329:301-11.
17. Fehrer C, Brunauer R, Laschober G. Reduced oxygen tension attenuates differentiation capacity of human mesenchymal stem cells and prolongs their lifespan. Aging Cell. 2007, 6:745-57.
18. Phinney DG, Prockop DJ. Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair-current views. Stem Cells. 2007, 25:2896-902.
19. Pittenger MF, Mackay AM, Beck SC. Multilineage potential of adult human mesenchymal stem cells. Science. 1999, 284:143-7.
20. Peister A, Mellad JA, Larson BL. Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential. Blood. 2004, 103:1662-8.
21. Fan Q, Yee CL, Ohyama M. Bone marrow-derived keratinocytes are not detected in normal skin and only rarely detected in wounded skin in two different murine models. Exp Hematol. 2006, 34:672-9.
22. Borue X, Lee S, Grove J. Bone marrow-derived cells contribute to epithelial engraftment during wound healing. Am J Pathol. 2004, 165:1767-72.
23. Brittan M, Braun KM, Reynolds LE. Bone marrow cells engraft within the epidermis and proliferate in vivo with no evidence of cell fusion. J Pathol. 2005, 205:1-13.
24. Aghi M, Chiocca EA. Contribution of bone marrow-derived cells to blood vessels in ischemic tissues and tumors. Mol Ther. 2005, 12:994-1005.
25. Chen L, Tredget EE, Wu PY. Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healing. PLoS ONE 2008, 3:e1886.
26. Beausejour CM, Krtolica A, Galimi F. Reversal of human cellular senescence: roles of the p53 and p16 pathways. EMBO J. 2003, 22:4212-22.
27. Butler JM, Guthrie SM, Koc M. SDF-1 is both necessary and sufficient to promote proliferative retinopathy. J Clin Invest. 2005, 115:86-93.
28. Petty JM, Sueblinvong V, Lenox CC. Pulmonary stromal-derived factor-1 expression and effect on neutrophil recruitment during acute lung injury. J Immunol. 2007, 178:8148-57.
29. Fierro FA, Brenner S, Oelschlaegel U. Combining SDF-1/CXCR4 antagonism and chemotherapy in relapsed acute myeloid leukemia. Leukemia. 2009, 23:393-6.
30. Mace KA, Hansen SL, Myers C. HOXA3 induces cell migration in endothelial and epithelial cells promoting angiogenesis and wound repair. J Cell Sci. 2005, 118:2567-77.
31. Gallagher KA, Liu ZJ, Xiao M. Diabetic impairments in NO-mediated endothelial progenitor cell mobilization and homing are reversed by hyperoxia and SDF-1 alpha. J Clin Invest. 2007, 117:1249-59.
32. Toksoy A, Muller V, Gillitzer R. Biphasic expression of stromal cell-derived factor-1 during human wound healing. Br J Dermatol. 2007, 157:1148-54.
33. Chan JC, Duszczyszyn DA, Castellino FJ. Accelerated skin wound healing in plasminogen activator inhibitor-1-deficient mice. Am J Pathol. 2001, 159:1681-8.
34. Lund LR, Romer J, Bugge TH. Functional overlap between two classes of matrix-degrading proteases in wound healing. EMBO J. 1999, 18:4645-56.
35. Madlener M. Differential expression of matrix metalloproteinases and their physiological inhibitors in acute murine skin wounds. Arch Dermatol Res 1998, 290:S24-9.
36. Campisi J, d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol. 2007, 8:729-40.
37. Rodier F, Campisi J, Bhaumik D. Two faces of p53: aging and tumor suppression. Nucleic Acids Res. 2007, 35:7475-84.
38. Aoshiba K, Tsuji T, Nagai A. Bleomycin induces cellular senescence in alveolar epithelial cells. Eur Respir J. 2003, 22:436-43.
39. Wang Y, Schulte BA, LaRue AC. Total body irradiation selectively induces murine hematopoietic stem cell senescence. Blood. 2006, 107:358-66.
40. Moskovits N, Kalinkovich A, Bar J. p53 Attenuates cancer cell migration and invasion through repression of SDF-1/CXCL12 expression in stromal fibroblasts. Cancer Res. 2006, 66:10671-6.
41. Coppe JP, Kauser K, Campisi J. Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence. J Biol Chem. 2006, 281:29568-74.
42. Ceradini DJ, Kulkarni AR, Callaghan MJ. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med. 2004, 10:858-64.
43. Nakayama T, Mutsuga N, Tosato G. FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc. Blood. 2007, 109:1363-72.
44. Greenhalgh DG, Sprugel KH, Murray MJ. PDGF and FGF stimulate wound healing in the genetically diabetic mouse. Am J Pathol. 1990, 136:1235-46.
45. Florin L, Maas-Szabowski N, Werner S. Increased keratinocyte proliferation by JUN-dependent expression of PTN and SDF-1 in fibroblasts. J Cell Sci. 2005, 118:1981-9.
46. Martin P. Wound healing-aiming for perfect skin regeneration. Science. 1997, 276:75-81.