Differential expression of matrix metalloproteinases and their physiological inhibitors in acute murine skin wounds

Archives of Dermatological Research, Supplement

Volumn 290, Issue , 1998, Pages

  Madlener, M ^a,b  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b NONE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; MATRIX METALLOPROTEINASE; STROMELYSIN; STROMELYSIN 2; TISSUE INHIBITOR OF METALLOPROTEINASE;

CONFERENCE PAPER; ENZYME ACTIVITY; EPITHELIZATION; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN INJURY; WOUND HEALING;

EID: 0031726308     PISSN: 09441948     EISSN: None     Source Type: Journal    
DOI: 10.1007/pl00007450     Document Type: Conference Paper

References (19)

1. Martin P (1997) Wound healing - aiming for perfect skin regeneration. Science 276:75-81
2. Mignatti P, Rifkin DB, Welgus HG, Parks WC (1996) Proteinases and tissue remodeling. In: Clark RAF (ed) The molecular and cellular biology of wound repair. Plenum, New York, pp 427-474
3. Rubin JS, Osada H, Finch PW, Taylor WG, Rudikoff S, Aaronson SA (1989) Purification and characterization of a newly identified growth factor specific for epithelial cells. Proc Natl Acad Sci USA 86:802-806
4. Brauchle M, Angermeyer K, Hubner G, Werner S (1994) Large induction of keratinocyte growth factor expression by serum growth factors and pro-inflarnmatory cytokines in cultured fibroblasts. Oncogene 9:3199-3204
5. Werner S, Smola H, Liao X, Longaker MT, Krieg T, Hofschneider PH, Williams LT (1994) The function of KGF in morphogenesis of epithelium and reepithelialization of wounds. Science 266:819-822
6. Frank S, Hübner G, Breier G, Longaker MT, Greenhalgh DG, Werner S (1995) Regulation of vascular endothelial growth factor expression in cultured keratinocytes. Implications for normal and impaired wound healing. J Biol Chem 270:12607-12613
7. Frank S, Munz B, Werner S (1997) The human homologue of a bovine non-selenium glutathione peroxidase is a novel keratinocyte growth factor-regulated gene. Oncogene 14:915-921
8. Tsuboi R, Sato C, Kurita Y, Ron D, Rubin JS, Ogawa H (1993) Keratinocyte growth factor (FGF-7) stimulates migration and plasminogen activator activity of normal human keratinocytes. J Invest Dermatol 101:49-63
9. Madlener M, Mauch C, Conca W, Brauchle M, Parks WC, Werner S (1996) Regulation of the expression of stromelysin-2 by growth factors in keratinocytes: implications for normal and impaired wound healing. Biochem J 320:659-664
10. Vaalamo M, Weckroth M, Puolakkainen P, Kere J, Saarinen P, Lauharanta J, Saarialho-Kere UK (1996) Patterns of matrix metalloproteinase and TIMP-1 expression in chronic and normally healing human cutaneous wounds. Br J Dermatol 135: 52-59
11. Okada A, Tomasetto C, Lutz Y, Bellocq JP, Rio MC, Basset P (1997) Expression of matrix metalloproteinases during rat skin wound healing: evidence that membrane type-1 matrix metalloproteinase is a stromal activator of pro-gelatinase A. J Cell Biol 137:67-77
12. Madlener M, Parks WC, Werner S (1998) Matrix metalloproteinases (MMPs) and their physiological inhibitors (TIMPs) are differentially expressed during excisional skin wound repair. Exp Cell Res 240 (in press)
13. Saarialho-Kere UK, Kovacs SO, Pentland AP, Parks WC (1994) Distinct populations of keratinocytes express stromelysin-1 and -2 in chronic wounds. J Clin Invest 94:79-88
14. Stricklin GP, Li L, Nanney L (1994) Localization of mRNAs representing interstitial collagenase, 72-kDa gelatinase, and TIMP in healing porcine burn wounds. J Invest Dermatol 103, 352-358
15. Stricklin GP, Li L, Jancic V, Wenczak B A, Nanney LB (1993) Localization of mRNAs representing collagenase and TIMP in sections of healing human burn wounds. Am J Pathol 143: 1657-1666
16. Ståhle-Bäckdahl M, Parks WC (1993) 92 kDa gelatinase is actively expressed by eosinophils and secreted by neutrophils in invasive squamous cell carcinoma. Am J Pathol 142:995-1000
17. Kinoh H, Sato H, Tsunezuka Y, Takino T, Kasashima A, Okada Y, Seiki M (1996) MT-MMP, the cell surface activator of proMMP-2 (pro-gelatinase A), is expressed with its substrate in mouse tissue during embryogenesis. J Cell Sci 109: 953-959
18. Shapiro SD, Griffin GL, Gilbert DJ, Jenkinds NA, Copeland NG, Welgus HG, Senior RM, Ley TJ (1992) Molecular cloning, chromosomal localization, and bacterial expression of a murine macrophage metalloelastase. J Biol Chem 267:4664-4671
19. Dong Z., Kumar R, Yang X, Fidler U (1997) Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma. Cell 88:801-810