Caffeic acid phenethyl ester is a potent inhibitor of HIF prolyl hydroxylase: structural analysis and pharmacological implication

Journal of Nutritional Biochemistry

Volumn 21, Issue 9, 2010, Pages 809-817

  Choi, Daekyu ^a   Han, Jeongoh ^a   Lee, Youna ^a   Choi, Jungyun ^a   Han, Songyi ^a   Hong, Sungchae ^a   Jeon, Hyunchu ^a   Kim, Young Mi ^a   Jung, Yunjin ^a  

^a Pusan National University   (South Korea)

Author keywords

Caffeic acid phenethylester; HIF prolyl hydroxylase; Hypoxia inducible factor 1; Ischemic reperfusion injury; Structure activity relationship

Indexed keywords

CAFFEIC ACID PHENETHYL ESTER; CATECHOL; HEME OXYGENASE 1; HIF PROLYL HYDROXYLASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IRON; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; DRUG POTENCY; ENZYME INHIBITION; HEART PROTECTION; HUMAN; HUMAN CELL; HYDROGENATION; ISCHEMIA; MICHAEL ADDITION; MOLECULAR MECHANICS; NONHUMAN; PROTEIN DEGRADATION; PROTEIN STRUCTURE; REPERFUSION INJURY; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; TRANSACTIVATION;

ANIMALS; CAFFEIC ACIDS; CELLS, CULTURED; ENZYME INHIBITORS; HEK293 CELLS; HEME OXYGENASE-1; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; PHENYLETHYL ALCOHOL; PROCOLLAGEN-PROLINE DIOXYGENASE; REPERFUSION INJURY; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; TUMOR CELLS, CULTURED; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

APIS MELLIFERA;

EID: 77955052559     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2009.06.002     Document Type: Article

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