Dietary hempseed meal intake increases body growth and shortens the larval stage via the upregulation of cell growth and sterol levels in Drosophila melanogaster

Molecules and Cells

Volumn 30, Issue 1, 2010, Pages 29-36

  Lee, Min Jung ^a   Park, Min Soo ^a   Hwang, Soojin ^a   Hong, Yoon Ki ^a   Choi, Gahee ^a   Suh, Yoon Seak ^a   Han, Seung Yeop ^a   Kim, Darae ^a   Jeun, Jungae ^b   Oh, Chun Taek ^c   Lee, Sung Joon ^b   Han, Sung Jun ^c   Kim, Donghak ^a   Kim, Eun Soo ^a   Jeong, Gilsang ^d   Cho, Kyoung Sang ^a  

^a Konkuk University   (South Korea)

^b Korea University   (South Korea)

^c Institute Pasteur Korea   (South Korea)

^d National Academy of Agricultural Science   (South Korea)

Author keywords

body growth; cholesterol; developmental rate; Drosophila; ecdysone; hempseed meal; reproduction

Indexed keywords

CAMPESTEROL; CANNABIS; ECDYSONE; HEMPSEED; HEXANE; PLANT EXTRACT; POLYUNSATURATED FATTY ACID; STEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BODY GROWTH; CELL GROWTH; CONTROLLED STUDY; DIETARY INTAKE; DROSOPHILA MELANOGASTER; EGG LAYING; FEMALE; LARVA; LARVAL DEVELOPMENT; LARVAL STAGE; LONGEVITY; MEAL; MOLTING; NONHUMAN; NUTRITIONAL VALUE; PLANT SEED; REPRODUCTION; SURVIVAL RATE;

ANIMALS; CANNABIS; CELL GROWTH PROCESSES; CHOLESTEROL; DIET; DROSOPHILA MELANOGASTER; EATING; FATTY ACIDS, UNSATURATED; FEMALE; LARVA; MALE; PLATELET AGGREGATION; SEEDS; STEROLS; SURVIVAL ANALYSIS; UP-REGULATION;

ANIMALIA; DROSOPHILA MELANOGASTER;

EID: 77955015434     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10059-010-0085-0     Document Type: Article

References (59)

1. A. Al-Khalifa T.G. Maddaford M.N. Chahine 2007 Effect of dietary hempseed intake on cardiac ischemia-reperfusion injury. American journal of physiology Am. J. Physiol. Regul. Integr. Comp. Physiol. 292 1198 1203
2. P.E. Caldwell M. Walkiewicz M. Stern 2005 Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release Curr. Biol. 15 1785 1795 10.1016/j.cub.2005.09.011 1:CAS:528: DC%2BD2MXhtFCjsL7K 16182526 (Pubitemid 41501513)
3. J.C. Callaway 2004 Hempseed as a nutritional resource: an overview Euphytica 140 65 72 10.1007/s10681-004-4811-6 (Pubitemid 40473738)
4. J. Callaway U. Schwab I. Harvima P. Halonen O. Mykkänen P. Hyvänen T. Järvinen 2005 Efficacy of dietary hempseed oil in patients with atopic dermatitis J. Dermatolog. Treat. 16 87 9 10.1080/09546630510035832 1:CAS:528:DC%2BD2MXjvFWqtb0%3D 16019622 (Pubitemid 40676907)
5. S. Chyb P. Raghu R.C. Hardie 1999 Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL Nature 397 255 259 10.1038/16703 1:CAS:528:DyaK1MXpvVGitA%3D%3D 9930700 (Pubitemid 29051174)
6. A.J. Clark K. Block 1959 The absence of sterol synthesis in insects J. Biol. Chem. 234 2578 2582 1:CAS:528:DyaF3cXisVyrsw%3D%3D 13810427
7. J. Colombani L. Bianchini S. Layalle E. Pondeville C. Dauphin-Villemant C. Antoniewski C. Carré S. Noselli P. Léopold 2005 Antagonistic actions of ecdysone and insulins determine final size in Drosophila Science 310 667 670 10.1126/science.1119432 1:CAS:528:DC%2BD2MXhtFChsLvF 16179433 (Pubitemid 41528157)
8. W.E. Connor C.A. DeFrancesco S.L. Connor 1993 N-3 fatty acids from fish oil. Effects on plasma lipoproteins and hypertriglyceridemic patients Ann. N. Y. Acad. Sci. 683 16 34 10.1111/j.1749-6632.1993.tb35689.x 1:CAS:528: DyaK3sXmt1Crur4%3D 8352438
9. J. Cooke J.H. Sang 1970 Utilization of sterols by larvae of Drosophila melanogaster J. Insect Physiol. 16 801 812 10.1016/0022-1910(70)90214-3 1:CAS:528:DyaE3cXktlars7c%3D 5449724
10. de Padua, L.S., Bunyaprafatsara, N., and Lemmens, R.H.M.J. (1999). Plant resources of South-East Asia: medicinal and poisonous plants (Leiden: Backhuys Publishers).
11. R.S. Edgecomb C.E. Harth A.M. Schneiderman 1994 Regulation of feeding behavior in adult Drosophila melanogaster varies with feeding regime and nutritional state J. Exp. Biol. 197 215 235 1:STN:280:DyaK2M7lsF2lsA%3D%3D 7852903
12. D. Fedor D.S. Kelley 2009 Prevention of insulin resistance by n-3 polyunsaturated fatty acids Curr. Opin. Clin. Nutr. Metab. Care 12 138 146 10.1097/MCO.0b013e3283218299 1:CAS:528:DC%2BD1MXhsFKksb4%3D 19202385
13. J.C. Fletcher C.S. Thummel 1995 The ecdysone-inducible Broad-complex and E74 early genes interact to regulate target gene transcription and Drosophila metamorphosis Genetics 141 1025 1035 1:CAS:528:DyaK28Xht1Clt78%3D 8582609
14. M.L. Fluegel T.J. Parker L.J. Pallanck 2006 Mutations of a Drosophila NPC1 gene confer sterol and ecdysone metabolic defects Genetics 172 185 196 10.1534/genetics.105.046565 1:CAS:528:DC%2BD28XhvVyqurY%3D 16079224 (Pubitemid 43345482)
15. Fox, S.I. (2009). Human physiology (Ohio: McGraw Hill Press).
16. L. Ge J. Wang W. Qi H.H. Miao J. Cao Y.X. Qu B.L. Li B.L. Song 2008 The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1 Cell Metab. 7 508 519 10.1016/j.cmet.2008.04.001 1:CAS:528:DC%2BD1cXnsVCkur0%3D 18522832 (Pubitemid 351729203)
17. M.A. Hashem K.Y. Jun E. Lee S. Lim H.Y. Choo Y. Kwon 2008 A rapid and sensitive screening system for human type I collagen with the aim of discovering potent anti-aging or antifibrotic compounds Mol. Cells 26 625 630 1:CAS:528:DC%2BD1MXptFyrsQ%3D%3D 18810249
18. A. Hessle M. Eriksson E. Nadeau T. Turner B. Johansson 2008 Cold-pressed hempseed cake as a protein feed for growing cattle Acta Agric. Scand. A Anim. Sci. 58 136 145
19. D.J. Holub B.J. Holub 2004 Omega-3 fatty acids from fish oils and cardiovascular disease Mol. Cell. Biochem. 263 217 225 10.1023/B:MCBI. 0000041863.11248.8d 1:CAS:528:DC%2BD2cXotlCrsLg%3D 15524182 (Pubitemid 39256160)
20. M.A. Horner K. Pardee S. Liu K. King-Jones G. Lajoie A. Edwards H.M. Krause C.S. Thummel 2009 The Drosophila DHR96 nuclear receptor binds cholesterol an regulates cholesterol homeostasis Genes Dev. 23 2711 2716 10.1101/gad.1833609 1:CAS:528:DC%2BD1MXhsFGqtL7L 19952106
21. X. Huang J.T. Warren L.I. Gilbert 2008 New players in the regulation of ecdysone biosynthesis J. Genet. Genomics 35 1 10 10.1016/S1673-8527(08)60001-6 18222403
22. I. Hullar I. Meleg S. Fekete R. Romvari 1999 Studies on the energy content of pigeon feeds I. Determination of digestibility and metabolizable energy content Poult. Sci. 78 1757 1762 1:STN:280:DC%2BD3c%2FptVSkug%3D%3D 10626652 (Pubitemid 129555073)
23. H.K. Kang B.S. Park 2007 Effects of dietary γ-fatty acids on the fatty acid composition of pork and plasma lipids in swine J. Food. Sci. Nutr. 36 563 568 1:CAS:528:DC%2BD2sXns1aksbk%3D
24. I. Karimi H. Hayatghaibi 2006 Effect of Cannabis sativa L. seed (hempseed) on lipid and protein profiles of rat Pakistan J. Nutrition 5 585 588 10.3923/pjn.2006.585.588
25. E.S. Kim P.G. Mahlberg 2003 Secretory vesicle formation in the secretory cavity of glandular trichomes of Cannabis sativa L. (cannabaceae) Mol. Cells 15 387 395 1:CAS:528:DC%2BD3sXmtFemsro%3D 12872998
26. T. Malini G. Vanithakumari 1990 Rat toxicity studies with β-sitosterol J. Ethnopharmacol. 28 221 234 10.1016/0378-8741(90)90032-O 1:CAS:528:DyaK3cXktFOrt7Y%3D 2329812
27. B. Matthäus L. Brühl 2008 Virgin hempseed oil: An interesting niche product Eur. J. Lipid Sci. Technol. 110 655 661 10.1002/ejlt.200700311
28. S.W. McKechnie B.W. Geer 1993 Long-chain dietary fatty acids affect the capacity of Drosophila melanogaster to tolerate ethanol J. Nutr. 123 106 116 1:CAS:528:DyaK3sXhtVSquro%3D 8421221
29. McPartland, J.M., Clarke, R.C., and Watson, D.P. (2000). Diseases and Pests of Cannabis. Hemp diseases and pests: management and biological control: an advanced treatise (Oxford: Pergamon Press).
30. T.A. Miettinen H. Gylling 2004 Plant stanol and sterol esters in prevention of cardiovascular diseases Ann. Med. 36 126 134 10.1080/ 07853890310021625 1:CAS:528:DC%2BD2cXjtFCns7w%3D 15119832 (Pubitemid 38510018)
31. K.T. Min S. Benzer 1999 Preventing neurodegeneration in the Drosophila mutant bubblegum Science 284 1985 1988 10.1126/science.284.5422.1985 1:CAS:528:DyaK1MXktVWnsbY%3D 10373116 (Pubitemid 29309445)
32. C. Mirth J.W. Truman L.M. Riddiford 2005 The role of the prothoracic gland in determining critical weight for metamorphosis in Drosophila melanogaster Curr. Biol. 15 1796 1807 10.1016/j.cub.2005.09.017 1:CAS:528:DC%2BD2MXhtFCjsL7L 16182527 (Pubitemid 41501514)
33. P.W. Moe H.F. Tyrrell N.W. Hooven Jr. 1973 Energy balance measurements with corn meal and ground oats for lactating cows J. Dairy Sci. 56 1149 1153 10.3168/jds.S0022-0302(73)85325-1
34. R.E. Monroe 1959 Role of cholesterol in house fly reproduction Nature 184 1513 10.1038/1841513a0 1:CAS:528:DyaF3cXltFKgsw%3D%3D 14423618
35. F. Mustafa J.J. Mckinnon D.A. Christenesen 1999 The nutritive value of hemp meal for ruminants Nurt. Update 79 91 95
36. H.F. Nijhout C.M. Williams 1974 Control of moulting and metamorphosis in the tobacco hornworm, Manduca sexta (L.): growth of the last-instar larva and the decision to pupate J. Exp. Biol. 61 481 491 1:CAS:528:DyaE2MXntVCmug%3D%3D 4443740
37. T. Ohtsu C. Katagiri M.T. Kimura S.H. Hori 1993 Cold adaptations in Drosophila. Qualitative changes of triacylglycerols with relation to overwintering J. Biol. Chem. 268 1830 1834 1:CAS:528:DyaK3sXhsVeqsL4%3D 8420958
38. J. Overgaard J.G. Sørensen S.O. Petersen V. Loeschcke M. Holmstrup 2005 Changes in membrane lipid composition following rapid cold hardening in Drosophila melanogaster J. Insect Physiol. 51 1173 1182 10.1016/j.jinsphys.2005. 06.007 1:CAS:528:DC%2BD2MXhtFKms7rE 16112133 (Pubitemid 41562689)
39. F. Panza V. Frisardi C. Capurso A. D'Introno A.M. Colacicco A. Di Palo B.P. Imbimbo G. Vendemiale A. Capurso V. Solfrizzi 2009 Polyunsaturated fatty acid and S-adenosylmethionine supplementation in predementia syndromes and Alzheimer's disease: a review Scientific World J. 9 373 389 1:CAS:528: DC%2BC3cXhsVSjtr0%3D
40. S. Parpal M. Karlsson H. Thorn P. Strålfors 2001 Cholesterol depletion disrupts caveolae and insulin receptor signaling for metabolic control via insulin receptor substrate-1, but not for mitogen-activated protein kinase control J. Biol. Chem. 276 9670 9678 10.1074/jbc.M007454200 1:CAS:528: DC%2BD3MXis1OltbY%3D 11121405
41. C.S. Patch L.C. Tapsell P.G. Williams M. Gordon 2006 Plant sterols as dietary adjuvants in the reduction of cardiovascular risk: theory and evidence Vasc. Health Risk Manag. 2 157 162 10.2147/vhrm.2006.2.2.157 1:CAS:528:DC%2BD28Xhtlars7zL 17319460 (Pubitemid 43853430)
42. M. Prociuk A. Edel N. Gavel J. Deniset R. Ganguly J. Austria B. Ander A. Lukas G. Pierce 2006 The effects of dietary hempseed on cardiac ischemia/reperfusion injury in hypercholesterolemic rabbits Exp. Clin. Cardiol. 11 198 205 1:CAS:528:DC%2BD28XhtF2lsLrM 18651032
43. M.A. Prociuk A.L. Edel M.N. Richard N.T. Gavel B.P. Ander C.M. Dupasquier G.N. Pierce 2008 Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseedenriched diet Can. J. Physiol. Pharmacol. 86 153 159 10.1139/Y08-011 1:CAS:528:DC%2BD1cXmtVejt7Y%3D 18418423 (Pubitemid 351536445)
44. Rees, H.H. (1985). Biosynthesis of ecdysone. Comprehensive Insect Physiology, Biochemistry and Pharmacology, Vol. 7 (Oxford: Pergamon Press).
45. H.H. Rees 1995 Ecdysteroid biosynthesis and inactivation in relation to function Eur. J. Entomol. 92 9 39 1:CAS:528:DyaK2MXlsVOgur4%3D
46. W.E. Robbins T.J. Shortino 1962 Effect of cholesterol in the larval diet on ovarian development in the adult house-fly Nature 194 502 503 10.1038/194502a0 1:CAS:528:DyaF38XktFyquro%3D 14492699
47. D.B. Rountree W.E. Bollenbacher 1986 The release of the prothoracicotropic hormone in the tobacco hornworm, Manduca sexta, is controlled intrinsically by juvenile hormone J. Exp. Biol. 120 41 58 1:CAS:528: DyaL28Xit1ahtb8%3D 3958672
48. th Ed. (Korea: National Academy of Agricultural Science, RDA).
49. U.S. Schwab J.C. Callaway M.I. Erkkil T. Järvinen 2006 Effects of hempseed and flaxseed oils on the profile of serum lipids, serum total and lipoprotein lipid concentrations and haemostatic factors Eur. J. Nutr. 45 470 477 10.1007/s00394-006-0621-z 1:CAS:528:DC%2BD2sXitVegsbw%3D 17103080 (Pubitemid 46020598)
50. F.G. Silversides M.R. Lefrançois 2005 The effect of feeding hempseed meal to laying hens Br. Poult. Sci. 46 231 235 10.1080/0071660500066183 1:CAS:528:DC%2BD2MXkt1Sltbk%3D 15957445 (Pubitemid 40764358)
51. W. Son P.L. Han Y.D. Chung 2008 The adenylyl cyclase encoded by rutabaga is required for larval molting in Drosophila Genes Genomics 30 163 171 1:CAS:528:DC%2BD1cXpt1aktLk%3D
52. Sullivan, W., Ashburner, M., and Hawley, R.S. (2000). Drosophila protocols. (New York: Cold Spring Harbor Laboratory Press).
53. Svoboda, J.A., and Thompson, M.J. (1985). Comprehensive insect physiology, biochemistry and pharmacology. Vol. 10. (Oxford: Pergamon Press).
54. J.A. Svoboda R.B. Imberski W.R. Lusby 1989 Drosophila melanogaster does not dealkylate [14C]sitosterol Experientia 45 983 985 10.1007/BF01953056 1:CAS:528:DyaK3cXhvFSltA%3D%3D
55. A.A. Teleman Y.W. Chen S.M. Cohen 2005 4E-BP functions as a metabolic brake used under stress conditions but not during normal growth Genes Dev. 19 1844 1848 10.1101/gad.341505 1:CAS:528:DC%2BD2MXpsFCqsr8%3D 16103212 (Pubitemid 41186984)
56. D.Q. Wang 2007 Regulation of intestinal cholesterol absorption Annu. Rev. Physiol. 69 221 248 10.1146/annurev.physiol.69.031905.160725 1:CAS:528:DC%2BD2sXltVaks7s%3D 17002594 (Pubitemid 46457642)
57. C.D. Webster K.R. Thompson A.M. Morgan E.J. Grisby A.L. Gannon 2000 Use of hemp seed meal, poultry by-product meal, and canola meal in practical diets without fish meal for sunshine bass (Morone chrysops ×M. saxatilis) Aquaculture 188 299 309 10.1016/S0044-8486(00)00338-0 (Pubitemid 30410988)
58. M. Wendel A.R. Heller 2009 Anticancer actions of omega-3 fatty acids-current state and future perspectives. anti-cancer agents in medicinal chemistry Anticancer Agents Med. Chem. 9 457 470 1:CAS:528:DC%2BD1MXlslOlsrY%3D 19442044
59. T. Yazicioglu A. Karaali 1983 On the fatty acid composition of Turkish vegetable oils Fette, Seifen, Anstrichm. 85 23 29 10.1002/lipi.19830850103 1:CAS:528:DyaL3sXht1Cnsb4%3D