Induction of interleukin-8 gene expression and protein secretion by C-reactive protein in ARPE-19 cells

Experimental Eye Research

Volumn 91, Issue 2, 2010, Pages 135-142

  Wang, Yu ^a   Bian, Zong Mei ^b   Yu, Wen Zhen ^a   Yan, Zheng ^a   Chen, Wei Chih ^a   Li, Xiao Xin ^a  

^a PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Age related macular degeneration; ARPE 19; C reactive protein; Interlukin 8

Indexed keywords

C REACTIVE PROTEIN; CD32 ANTIGEN; CD64 ANTIGEN; FC RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; STRESS ACTIVATED PROTEIN KINASE; VASCULOTROPIN;

ARTICLE; CELL LINE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION; GENE INDUCTION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MESSENGER RNA SYNTHESIS; NUCLEOTIDE SEQUENCE; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; TRANSIENT EXPRESSION;

C-REACTIVE PROTEIN; CELL LINE; CHEMOKINE CCL2; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMANS; INTERLEUKIN-8; MICROSCOPY, FLUORESCENCE; NF-KAPPA B; RETINAL PIGMENT EPITHELIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77954954516     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2010.02.008     Document Type: Article

References (58)

1. Anderson D.H., Mullins R.F., Hageman G.S., Johnson L.V. A role for local inflammation in the formation of drusen in the aging eye. Am. J. Ophthalmol. 2002, 134:411-431.
2. Bang R., Marnell L., Mold C., Stein M.P., Clos K.T., Chivington-Buck C., Clos T.W. Analysis of binding sites in human C-reactive protein for Fc{gamma}RI, Fc{gamma}RIIA, and C1q by site-directed mutagenesis. J. Biol. Chem. 2005, 280:25095-25102.
3. Barna B.P., Thomassen M.J., Zhou P., Pettay J., Singh-Burgess S., Deodhar S.D. Activation of alveolar macrophage TNF and MCP-1 expression in vivo by a synthetic peptide of C-reactive protein. J. Leukoc. Biol. 1996, 59:397-402.
4. Belperio J.A., Keane M.P., Arenberg D.A., Addison C.L., Ehlert J.E., Burdick M.D., Strieter R.M. CXC chemokines in angiogenesis. J. Leukoc. Biol. 2000, 68:1-8.
5. Bian Z.M., Elner V.M., Yoshida A., Kunkel S.L., Elner S.G. Signaling pathways for glycated human serum albumin-induced IL-8 and MCP-1 secretion in human RPE cells. Invest. Ophthalmol. Vis. Sci. 2001, 42:1660-1668.
6. Black S., Kushner I., Samols D. C-reactive protein. J. Biol. Chem. 2004, 279:48487-48490.
7. Boekhoorn S.S., Vingerling J.R., Witteman J.C., Hofman A., de Jong P.T. C-reactive protein and risk of aging macular disorder: the Rotterdam Study. Arch. Ophthalmol. 2007, 125:1396-1401.
8. Chang J.W., Kim C.S., Kim S.B., Park S.K., Park J.S., Lee S.K. C-reactive protein induces NF-κB activation through intracellular calcium and ROS in human mesangial cells. Nephron Exp. Nephrol. 2005, 101:e165-e172.
9. Chen Y., Wang J., Yao Y., Yuan W., Kong M., Lin Y., Geng D., Nie R. CRP regulates the expression and activity of tissue factor as well as tissue factor pathway inhibitor via NF-kappaB and ERK 1/2 MAPK pathway. FEBS Lett. 2009, 583:2811-2818.
10. Curcio C.A., Millican C.L., Bailey T., Kruth H.S. Accumulation of cholesterol with age in human Bruch's membrane. Invest. Ophthalmol. Vis. Sci. 2001, 42:265-274.
11. Da Silva D.M., Velders M.P., Nieland J.D., Schiller J.T., Nickoloff B.J., Kast W.M. Physical interaction of human papillomavirus virus-like particles with immune cells. Int. Immunol. 2001, 13:633-641.
12. Dehghan A., Kardys I., de Maat M.P., Uitterlinden A.G., Sijbrands E.J., Bootsma A.H., Stijnen T., Hofman A., Schram M.T., Witteman J.C. Genetic variation, C-reactive protein levels, and incidence of diabetes. Diabetes 2007, 56:872-878.
13. Devaraj S., Dasu M.R., Singh U., Rao L.V., Jialal I. C-reactive protein stimulates superoxide anion release and tissue factor activity in vivo. Atherosclerosis 2009, 203:67-74.
14. Devaraj S., Davis B., Simon S.I., Jialal I. CRP promotes monocyte-endothelial cell adhesion via Fcγ receptors in human aortic endothelial cells under static and shear flow conditions. Am. J. Physiol. Heart Circ. Physiol. 2006, 291:H1170-H1176.
15. Devaraj S., Du Clos T.W., Jialal I. Binding and internalization of C-reactive protein by Fc gamma receptors on human aortic endothelial cells mediates biological effects. Arterioscler. Thromb. Vasc. Biol. 2005, 25:1359-1363.
16. Devaraj S., Kumaresan P.R., Jialal I. Effect of C-reactive protein on chemokine expression in human aortic endothelial cells. J. Mol. Cell. Cardiol. 2004, 36:405-410.
17. Elner V.M., Schaffne T., Taylor K., Glagov S. Immunophagocytic properties of retinal pigment epithelium cells. Science 1981, 4477:74-76.
18. Enjoji M., Nakamuta M., Yamaguchi K., Ohta S., Kotoh K., Fukushima M., Kuniyoshi M., Yamada T., Tanaka M., Nawata H. Clinical significance of serum levels of vascular endothelial growth factor and its receptor in biliary disease and carcinoma. World J. Gastroenterol. 2005, 11:1167-1171.
19. Erlinger T.P., Platz E.A., Rifai N., Helzlsouer K.J. C-reactive protein and the risk of incident colorectal cancer. JAMA 2004, 291:585-590.
20. Grossniklaus H.E., Miskala P.H., Green W.R., Bressler S.B., Hawkins B.S., Toth C., Wilson D.J., Bressler N.M. Histopathologic and ultrastructural features of surgically excised subfoveal choroidal neovascular lesions: submacular surgery trials report no. 7. Arch. Ophthalmol. 2005, 123:914-921.
21. Han K.H., Hong K.H., Park J.H., Ko J., Kang D.H., Choi K.J., Hong M.K., Park S.W., Park S.J. C-reactive protein promotes monocyte chemoattractant protein-1 mediated chemotaxis through upregulating CC chemokine receptor 2 expression in human monocytes. Circulation 2004, 109:2566-2571.
22. Hanriot D., Bello G., Ropars A., Seguin-Devaux C., Poitevin G., Grosjean S., Latger-Cannard V., Devaux Y., Zannad F., Regnault V., Lacolley P., Mertes P.M., Hess K., Longrois D. C-reactive protein induces pro- and anti-inflammatory effects, including activation of the liver X receptor alpha, on human monocytes. Thromb. Haemost. 2008, 99:558-569.
23. Hattori Y., Matsumura M., Kasai K. Vascular smooth muscle cell activation by C-reactive protein. Cardiovasc. Res. 2003, 58:186-195.
24. Heinzmann A., Ahlert I., Kurz T., Berner R., Deichmann K.A. Association study suggests opposite effects of polymorphisms within IL-8 on bronchial asthma and respiratory syncytial virus bronchiolitis. J. Allergy Clin. Immunol. 2004, 114:671-676.
25. van Hecke M.V., Dekker J.M., Nijpels G., Moll A.C., Heine R.J., Bouter L.M., Polak B.C., Stehouwer C.D. Inflammation and endothelial dysfunction are associated with retinopathy: the Hoorn Study. Diabetologia 2005, 48:1300-1306.
26. Johnson P.T., Betts K.E., Radeke M.J., Hageman G.S., Anderson D.H., Johnson L.V. Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:17456-17461.
27. Kaarniranta K., Salminen A. Age-related macular degeneration: activation of innate immunity system via pattern recognition receptors. J. Mol. Med. 2009, 87:117-123.
28. Khreiss T., József L., Potempa L.A., Filep J.G. Conformational rearrangement in C-reactive protein is required for proinflammatory actions on human endothelial cells. Circulation 2004, 109:2016-2022.
29. Khreiss T., Jozsef L., Potempa L.A., Filep J.G. Loss of pentameric symmetry of C-reactive protein induces interleukin-8 production through peroxynitrite signaling in human neutrophils. FASEB J. 2006, 20:A1084.
30. Kibayashi E., Urakaze M., Kobashi C., Kishida M., Takata M., Sato A., Yamazaki K., Kobayashi M. Inhibitory effect of pitavastatin (NK-104) on the C-reactive-protein-induced interleukin-8 production in human aortic endothelial cells. Clin. Sci. (Lond.) 2005, 108:515-521.
31. Kikuchi M., Nakamura M., Ishikawa K., Suzuki T., Nishihara H., Yamakoshi T., Nishio K., Taki K., Niwa T., Hamajima N., Terasaki H. Elevated C-reactive protein levels in patients with polypoidal choroidal vasculopathy and patients with neovascular age-related macular degeneration. Ophthalmology 2007, 114:1722-1727.
32. Klein R., Peto T., Bird A., Vannewkirk M.R. The epidemiology of age-related macular degeneration. Am. J. Ophthalmol. 2004, 137:486-495.
33. Lau D.C., Dhillon B., Yan H., Szmitko P.E., Verma S. Adipokines: molecular links between obesity and atheroslcerosis. Am. J. Physiol. Heart Circ. Physiol. 2005, 288:H2031-H2041.
34. Lim M.Y., Wang H., Kapoun A.M., O'connell M., O'Young G., Brauer H.A., Luedtke G.R., Chakravarty S., Dugar S., Schreiner G.S., Protter A.A., Higgins L.S. p38 Inhibition attenuates the pro-inflammatory response to C-reactive protein by human peripheral blood mononuclear cells. J. Mol. Cell. Cardiol. 2004, 37:1111-1114.
35. van Leeuwen R., Klaver C.C., Vingerling J.R., Hofman A., de Jong P.T. Epidemiology of age-related maculopathy: a review. Eur. J. Epidemiol. 2003, 18:845-854.
36. Mineo C., Gormley A.K., Yuhanna I.S., Osborne-Lawrence S., Gibson L.L., Hahner L., Shohet R.V., Black S., Salmon J.E., Samols D., Karp D.R., Thomas G.D., Shaul P.W. FcγRIIB mediates C-reactive protein inhibition of endothelial NO synthase. Circ. Res. 2005, 97:1124-1131.
37. Paffen E., deMaat M.P. C-reactive protein in atherosclerosis: a causal factor?. Cardiovasc. Res. 2006, 71:30-39.
38. Pasceri V., Cheng J.S., Willerson J.T., Yeh E.T. Modulation of C-reactive protein-mediated monocyte chemoattractant protein-1 induction in human endothelial cells by anti-atherosclerosis drugs. Circulation 2001, 103:2531-2534.
39. Pasceri V., Willerson J.T., Yeh E.T.H. Direct proinflammatory effect of C-reactive protein on human endothelial cells. Circulation 2000, 102:2165-2168.
40. Pepys M.B., Hirschfield G.M. C-reactive protein: a critical update. J. Clin. Invest. 2003, 111:1805-1812.
41. Rocker C., Manolov D.E., Kuzmenkina E.V., Tron K., Slatosch H., Torzewski J., Nienhaus G.U. Affinity of C-reactive protein toward FcgammaRI is strongly enhanced by the gamma-chain. Am. J. Pathol. 2007, 170:755-763.
42. Ryu J., Lee C.W., Shin J.A., Park C.S., Kim J.J., Park S.J., Han K.H. Fc gammaRIIa mediates C-reactive protein-induced inflammatory responses of human vascular smooth muscle cells by activating NADPH oxidase 4. Cardiovasc. Res. 2007, 75:555-565.
43. Sandilands G.P., Burnett E.R., MacPherson S.A., Downie I., More I.A., MacSween R.N. Demonstration of cytoplasmic CD32 (Fc gamma RII) within human lymphocytes following microwave treatment. Immunology 1997, 90:427-434.
44. Schwedler S.B., Hansen-Hagge T., Reichert M., Schmiedeke D., Schneider R., Galle J., Potempa L.A., Wanner C., Filep J.G. Monomeric C-reactive protein decreases acetylated LDL uptake in human endothelial cells. Clin. Chem. 2009, 55:1728-1731.
45. Seddon J.M., George S., Rosner B., Rifai N. Progression of age-related macular degeneration: prospective assessment of C-reactive protein, interleukin 6, and other cardiovascular biomarkers. Arch. Ophthalmol. 2005, 123:774-782.
46. Seddon J.M., Gensler G., Milton R.C., Klein M.L., Rifai N. Association between C-reactive protein and age-related macular degeneration. JAMA 2004, 291:704-710.
47. Singh U., Devaraj S., Dasu M.R., Ciobanu D., Reusch J., Jialal I. C-reactive protein decreases interleukin-10 secretion in activated human monocyte-derived macrophages via inhibition of cyclic AMP production. Arterioscler. Thromb. Vasc. Biol. 2006, 26:2469-2475.
48. Sorkin A., McClure M., Huang F., Carter R. Interaction of EGF receptor and grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy. Curr. Biol. 2000, 10:1395-1398.
49. Taub D.D., Proost P., Murphy W.J., Anver M., Longo D.L., van Damme J., Oppenheim J.J. Monocyte chemotactic protein-1 (MCP-1), -2, and -3 are chemotactic for human T lymphocytes. J. Clin. Invest. 1995, 95:1370-1376.
50. Wang Q., Zhu X., Xu Q., Ding X., Chen Y.E., Song Q. Effect of C-reactive protein on gene expression in vascular endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 2005, 288:H1539-H1545.
51. Woollard K.J., Phillips D.C., Griffiths H.R. Direct modulatory effect of C-reactive protein on primary human monocyte adhesion to human endothelial cells. Clin. Exp. Immunol. 2002, 130:256-262.
52. Xie L., Chang L., Guan Y., Wang X. C-reactive protein augments interleukin-8 secretion in human peripheral blood monocytes. J. Cardiovasc. Pharmacol. 2005, 46:690-696.
53. Xu J.W., Morita I., Ikeda K., Miki T., Yamori Y. C-reactive protein suppresses insulin signaling in endothelial cells: role of spleen tyrosine kinase. Mol. Endocrinol. 2007, 21:564-573.
54. Yeh E.T. CRP as a mediator of disease. Circulation 2004, 109:II11-II14.
55. Zacho J., Tybjaerg-Hansen A., Jensen J.S., Grande P., Sillesen H., Nordestgaard B.G. Genetically elevated C-reactive protein and ischemic vascular disease. N. Engl. J. Med. 2008, 359:1897-1908.
56. Zhang R., Becnel L., Li M., Chen C., Yao Q. C-reactive protein impairs human CD14+ monocyte-derived dendritic cell differentiation, maturation and function. Eur. J. Immunol. 2006, 36:2993-3006.
57. Zhou P., Thomassen M.J., Pettay J., Deodhar S.D., Barna B.P. Human monocytes produce monocyte chemoattractant protein 1 (MCP-1) in response to a synthetic peptide derived from C-reactive protein. Clin. Immunol. Immunopathol. 1995, 74:84-88.
58. Zen Q., Zhong W., Mortensen R.F. Binding site on human C-reactive protein (CRP) recognized by the leukocyte CRP-receptor. J. Cell. Biochem. 1997, 64:140-151.