Conformational Rearrangement in C-Reactive Protein Is Required for Proinflammatory Actions on Human Endothelial Cells

Circulation

Volumn 109, Issue 16, 2004, Pages 2016-2022

  Khreiss, Tarek ^a   József, Levente ^a   Potempa, Lawrence A ^b   Filep, János G ^a  

^a MAISONNEUVE ROSEMONT HOSPITAL   (Canada)

^b Immtech International Inc   (United States)

Author keywords

Cell adhesion molecules; Endothelium; Inflammation; Proteins; Signal transduction

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; C REACTIVE PROTEIN; CELL ADHESION MOLECULE; CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; SYNAPTOPHYSIN; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; CELL ACTIVATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOPATHOLOGY; INFLAMMATION; LEUKOCYTE ACTIVATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

C-REACTIVE PROTEIN; CELL ADHESION; CELL ADHESION MOLECULES; CHEMOKINE CCL2; CORONARY VESSELS; ENDOTHELIUM, VASCULAR; HUMANS; INFLAMMATION; INTERLEUKIN-8; MITOGEN-ACTIVATED PROTEIN KINASES; NEUTROPHILS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN CONFORMATION; RECEPTORS, IMMUNOLOGIC;

EID: 2142751587     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000125527.41598.68     Document Type: Article

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