Affinity of C-reactive protein toward FcγRI is strongly enhanced by the γ-chain

American Journal of Pathology

Volumn 170, Issue 2, 2007, Pages 755-763

  Röcker, Carlheinz ^a   Manolov, Dimitar E ^a   Kuzmenkina, Elza V ^a   Tron, Kyrylo ^a   Slatosch, Holger ^a   Torzewski, Jan ^a   Nienhaus, G Ulrich ^a,b  

^a UNIVERSITY OF ULM   (Germany)

^b University of Illinois at Urbana Champaign   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; IMMUNOGLOBULIN G; MEMBRANE RECEPTOR; FC RECEPTOR; FCGR1A PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL SURFACE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DISSOCIATION; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC CODE; GENETIC TRANSFECTION; KINETICS; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; ANIMAL; CAPPING PHENOMENON; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; GENETICS; HUMAN; METABOLISM; PROTEIN BINDING; PROTEIN QUATERNARY STRUCTURE;

ANIMALS; C-REACTIVE PROTEIN; CERCOPITHECUS AETHIOPS; COS CELLS; HUMANS; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; RECEPTOR AGGREGATION; RECEPTORS, IGG;

EID: 33947511553     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2007.060734     Document Type: Article

References (39)

1. Mortensen RF: C-reactive protein, inflammation, and innate immunity. Immunol Res 2001, 24:163-176
2. Black S, Kushner I, Samols D: C-reactive protein. J Biol Chem 2004, 279:48487-48490
3. Pepys MB, Hirschfield GM: C-reactive protein: a critical update. J Clin Invest 2003, 111:1805-1812
4. Ridker PM, Cannon CP, Morrow D, Rifai N, Rose LM, McCabe CH, Pfeffer MA, Braunwald E: C-reactive protein levels and outcomes after statin therapy. N Engl J Med 2005, 352:20-28
5. Manolov DE, Koenig W, Hombach V, Torzewski J: C-reactive protein and atherosclerosis. Is there a causal link. Histol Histopathol 2003, 18:1189-1193
6. Torzewski J: C-reactive protein and atherogenesis: new insights from established animal models. Am J Pathol 2005, 167:923-925
7. Scirica BM, Morrow DA: Is C-reactive protein an innocent bystander or proatherogenic culprit? The verdict is still out. Circulation 2006, 113:2128-2134; discussion 2151
8. Pepys MB, Hirschfield GM, Tennent GA, Gallimore JR, Kahan MC, Bellotti V, Hawkins PN, Myers RM, Smith MD, Polara A, Cobb AJ, Ley SV, Aquilina JA, Robinson CV, Sharif I, Gray GA, Sabin CA, Jenvey MC, Kolstoe SE, Thompson D, Wood SP: Targeting C-reactive protein for the treatment of cardiovascular disease. Nature 2006, 440:1217-1221
9. Tebo JM, Mortensen RF: Characterization and isolation of a C-reactive protein receptor from the human monocytic cell line U-937. J Immunol 1990, 144:231-238
10. Bharadwaj D, Stein MP, Volzer M, Mold C, Du Clos TW: The major receptor for C-reactive protein on leukocytes is Fcgamma receptor II. J Exp Med 1999, 190:585-590
11. Saeland E, van Royen A, Hendriksen K, Vile-Weekhout H, Rijkers GT, Sanders LA, van de Winkel JG: Human C-reactive protein does not bind to FcgammaRIIa on phagocytic cells. J Clin Invest 2001, 107:641-643
12. Chi M, Tridandapani S, Zhong W, Coggeshall KM, Mortensen RF: C-reactive protein induces signaling through Fc gamma RIIa on HL-60 granulocytes. J Immunol 2002, 168:1413-1418
13. Bodman-Smith KB, Gregory RE, Harrison PT, Raynes JG: FcgammaRIIa expression with FcgammaRI results in C-reactive protein- and IgG-mediated phagocytosis. J Leukoc Biol 2004, 75:1029-1035
14. Bang R, Marnell L, Mold C, Stein MP, Du Clos KT, Chivington-Buck C, Du Clos TW: Analysis of binding sites in human C-reactive protein for FcgammaRI, FcgammaRIIA, and C1q by site-directed mutagenesis. J Biol Chem 2005, 280:25095-25102
15. Raghavan M, Bjorkman PJ: Fc receptors and their interactions with immunoglobulins. Annu Rev Cell Dev Biol 1996, 12:181-220
16. Ravetch JV, Bolland S: IgG Fc receptors. Annu Rev Immunol 2001, 19:275-290
17. Miller KL, Duchemin AM, Anderson CL: A novel role for the Fc receptor gamma subunit: enhancement of Fc gamma R ligand affinity. J Exp Med 1996, 183:2227-2233
18. Marnell LL, Mold C, Volzer MA, Burlingame RW, Du Clos TW: C-reactive protein binds to Fc gamma RI in transfected COS cells. J Immunol 1995, 155:2185-2193
19. Stein MP, Edberg JC, Kimberly RP, Mangan EK, Bharadwaj D, Mold C, Du Clos TW: C-reactive protein binding to FcgammaRIIa on human monocytes and neutrophils is allele-specific. J Clin Invest 2000, 105:369-376
20. Wiedenmann J, Schenk A, Röcker C, Girod A, Spindler KD, Nienhaus GU: A far-red fluorescent protein with fast maturation and reduced oligomerization tendency from Entacmaea quadricolor (Anthozoa, Actinaria). Proc Natl Acad Sci USA 2002, 99:11646-11651
21. Manolov DE, Röcker C, Hombach V, Nienhaus GU, Torzewski J: Ultrasensitive confocal fluorescence microscopy of C-reactive protein interacting with FcgammaRIIa. Arterioscler Thromb Vasc Biol 2004, 24:2372-2377
22. Bodman-Smith KB, Melendez AJ, Campbell I, Harrison PT, Allen JM, Raynes JG: C-reactive protein-mediated phagocytosis and phospholipase D signalling through the high-affinity receptor for immunoglobulin G (FcgammaRI). Immunology 2002, 107:252-260
23. van Vugt MJ, Heijnen AF, Capel PJ, Park SY, Ra C, Saito T, Verbeek JS, van de Winkel JG: FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo. Blood 1996, 87:3593-3599
24. Hundt M, Zielinska-Skowronek M, Schmidt RE: Lack of specific receptors for C-reactive protein on white blood cells. Eur J Immunol 2001, 31:3475-3483
25. Schenk A, Ivanchenko S, Röcker C, Wiedenmann J, Nienhaus GU: Photodynamics of red fluorescent proteins studied by fluorescence correlation spectroscopy. Biophys J 2004, 86:384-394
26. Manders EMM, Verbeek FJ, Aten JA: Measurement of co-localization of objects in dual-colour confocal images. J Microsc 1993, 169:375-382
27. Wiehe JMI, Niesler C, Torzewski J, Zimmermann O, Wiesneth M, Schmitt M, Schwarz K, Döhner H, Hombach V, Greiner G: Efficient transient genetic labeling of human CD34+ progenitor cells for in vivo application. Regen Med 2006, 1:223-234
28. Volanakis JE: Complement activation by C-reactive protein complexes. Ann NY Acad Sci 1982, 389:235-250
29. Mortensen RF, Osmand AP, Lint TF, Gewurz H: Interaction of C-reactive protein with lymphocytes and monocytes: complement-dependent adherence and phagocytosis. J Immunol 1976, 117:774-781
30. Sun H, Koike T, Ichikawa T, Hatakeyama K, Shiomi M, Zhang B, Kitajima S, Morimoto M, Watanabe T, Asada Y, Chen YE, Fan J: C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance. Am J Pathol 2005, 167:1139-1148
31. Reifenberg K, Lehr HA, Baskal D, Wiese E, Schaefer SC, Black S, Samols D, Torzewski M, Lackner KJ, Husmann M, Blettner M, Bhakdi S: Role of C-reactive protein in atherogenesis: can the apolipoprotein E knockout mouse provide the answer. Arterioscler Thromb Vasc Biol 2005, 25:1641-1646
32. Torzewski J, Torzewski M, Bowyer DE, Frohlich M, Koenig W, Waltenberger J, Fitzsimmons C, Hombach V: C-reactive protein frequently colocalizes with the terminal complement complex in the intima of early atherosclerotic lesions of human coronary arteries. Arterioscler Thromb Vasc Biol 1998, 18:1386-1392
33. Torzewski M, Rist C, Mortensen RF, Zwaka TP, Bienek M, Waltenberger J, Koenig W, Schmitz G, Hombach V, Torzewski J: C-reactive protein in the arterial intima: role of C-reactive protein receptor-dependent monocyte recruitment in atherogenesis. Arterioscler Thromb Vasc Biol 2000, 20:2094-2099
34. Zwaka TP, Hombach V, Torzewski J: C-reactive protein-mediated low density lipoprotein uptake by macrophages: implications for atherosclerosis. Circulation 2001, 103:1194-1197
35. Pasceri V, Willerson JT, Yeh ET: Direct proinflammatory effect of C-reactive protein on human endothelial cells. Circulation 2000, 102:2165-2168
36. Verma S, Li SH, Badiwala MV, Weisel RD, Fedak PW, Li RK, Dhillon B, Mickle DA: Endothelin antagonism and interleukin-6 inhibition attenuate the proatherogenic effects of C-reactive protein. Circulation 2002, 105:1890-1896
37. Taylor KE, Giddings JC, van den Berg CW: C-reactive protein-induced in vitro endothelial cell activation is an artifact caused by azide and lipopolysaccharide. Arterioscler Thromb Vasc Biol 2005, 25:1225-1230
38. Swafford Jr AN, Bratz IN, Knudson JD, Rogers PA, Timmerman JM, Tune JD, Dick GM: C-reactive protein does not relax vascular smooth muscle: effects mediated by sodium azide in commercially available preparations. Am J Physiol 2005, 288:H1786-H1795
39. Oroszlan M, Herczenik E, Rugonfalvi-Kiss S, Roos A, Nauta AJ, Daha MR, Gombos I, Karadi I, Romics L, Prohaszka Z, Fust G, Cervenak L: Proinflammatory changes in human umbilical cord vein endothelial cells can be induced neither by native nor by modified CRP. Int Immunol 2006, 18:871-878