αB-crystallin is a target for adaptive immune responses and a trigger of innate responses in preactive multiple sclerosis lesions

Journal of Neuropathology and Experimental Neurology

Volumn 69, Issue 7, 2010, Pages 694-703

  Van Noort, Johannes M ^a,b   Bsibsi, Malika ^a,b   Gerritsen, Wouter H ^c   Van Der Valk, Paul ^c   Bajramovic, Jeffrey J ^d   Steinman, Lawrence ^e   Amor, Sandra ^c,f  

^a TNO   (Netherlands)

^b Delta Crystallon BV   (Netherlands)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^d BIOMEDICAL PRIMATE RESEARCH CENTRE   (Netherlands)

^e STANFORD UNIVERSITY   (United States)

^f QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

B crystallin; Autoantibodies; Microglia; Multiple sclerosis; Preactive lesions

Indexed keywords

ALPHA B CRYSTALLIN; ANTIBODY; CCL1 CHEMOKINE; CHEMOKINE; CRYSTALLIN; HLA DR ANTIGEN; IMMUNOGLOBULIN G; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; MYELIN PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ALPHA CRYSTALLIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CYTOKINE; GLIAL FIBRILLARY ACIDIC PROTEIN; NERVE PROTEIN; NEUROFILAMENT PROTEIN; NEUROFILAMENT PROTEIN L; OLIG2 PROTEIN, HUMAN; PROTEOLIPID PROTEIN;

ADAPTIVE IMMUNITY; ADULT; ANTIBODY BLOOD LEVEL; ARTICLE; CELL ACTIVATION; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; INNATE IMMUNITY; MALE; MICROGLIA; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; PROTEIN SECRETION; WHITE MATTER; IMMUNOLOGY; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; MIDDLE AGED; OLIGODENDROGLIA; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADAPTIVE IMMUNITY; ADULT; ALPHA-CRYSTALLINS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CYTOKINES; GLIAL FIBRILLARY ACIDIC PROTEIN; HLA-DR ANTIGENS; HUMANS; MASS SPECTROMETRY; MICROGLIA; MIDDLE AGED; MULTIPLE SCLEROSIS; MYELIN PROTEOLIPID PROTEIN; NERVE TISSUE PROTEINS; NEUROFILAMENT PROTEINS; OLIGODENDROGLIA;

EID: 77954699176     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/NEN.0b013e3181e4939c     Document Type: Article

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