Magnetization transfer changes in the normal appearing white matter precede the appearance of enhancing lesions in patients with multiple sclerosis

Annals of Neurology

Volumn 43, Issue 6, 1998, Pages 809-814

  Filippi, Massimo ^a   Rocca, Maria A ^a   Martino, Gianvito ^a   Horsfield, Mark A ^b   Comi, Giancarlo ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM PENTETATE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC IMAGING; FEMALE; HUMAN; IMAGE ANALYSIS; MALE; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; WHITE MATTER;

ADULT; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; HUMANS; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MAGNETICS; MALE; MULTIPLE SCLEROSIS; MYELIN SHEATH; NERVE FIBERS; PROTONS;

EID: 0031839220     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.410430616     Document Type: Article

References (34)

1. Martin R, McFarland HF, McFarlin DE. Immunological aspects of demyelinating diseases. Annu Rev Immunol 1992;10: 153-187
2. Steinman L. A few autoreactive cells in an autoimmune infiltrate control a vast population of non specific cells: a tale of smart bombs and the infantry. Proc Natl Acad Sci USA 1996; 93:2253-2256
3. Goverman J, Woods A, Larson L, et al. Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity. Cell 1993;72:551-560
4. Lafaille JJ, Nagashima K, Katsuki M, Tonegawa S. High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell 1994;78:399-408
5. McDonald WI, Miller DH, Barnes D. The pathological evolution of multiple sclerosis. Neuropathol Appl Neurobiol 1992; 18:319-334
6. Katz D, Taubenberger JK, Cannella B, et al. Correlation between magnetic resonance imaging findings and lesion development in multiple sclerosis. Ann Neurol 1993;34:661-669
7. Grossman RI. Magnetization transfer in multiple sclerosis. Ann Neurol 1994;36(Suppl):S97-S99
8. Dousset V, Grossman RI, Ramer NK, et al. Experimental allergic encephalomyelitis and multiple sclerosis: lesion characterization with magnetization transfer imaging. Radiology 1992; 182:483-491
9. Filippi M, Campi A, Dousset V, et al. A magnetization transfer imaging study of normal-appearing white matter in multiple sclerosis. Neurology 1995;45:478-482
10. Loevner LA, Grossman RI, Cohen JA, et al. Microscopic disease in normal-appearing white matter on conventional MR images in patients with multiple sclerosis: assessment with magnetization-transfer measurements. Radiology 1995;196:511-515
11. Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983;13:227-231
12. Lublin FD, Reingold SC, the National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. Defining the clinical course of multiple sclerosis: results of an international survey. Neurology 1996;46:907-911
13. Kurtzke JF. Rating neurological impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33:1444-1452
14. Miller DH, Barkhof F, Berry I, et al. Magnetic resonance imaging in monitoring the treatment of multiple sclerosis: concerted action guidelines. J Neurol Neurosurg Psychiatry 1991; 54:683-688
15. 2-weighted images. J Neurol 1997;244:266-270
16. Friston KJ, Ashburner J, Poline JB, et al. Spatial realignment and normalization of images. Hum Brain Mapping 1995;3: 165-189
17. Allen IV, McKeown SR. A histological, histochemical and biochemical study of the macroscopically normal white matter in multiple sclerosis. J Neurol Sci 1979;41:81-91
18. Lai HM, Davie CA, Gass A, et al. Serial magnetisation transfer ratios in gadolinium-enhancing lesions in multiple sclerosis. J Neurol 1997;244:308-311
19. Filippi M, Yousry T, Campi A, et al. Comparison of triple dose versus standard dose gadolinium-DTPA for detection of MRI enhancing lesions in patients with MS. Neurology 1996;46: 379-384
20. Wong KT, Grossman RI, Boorstein JM, et al. Magnetization transfer imaging of periventricular hyperintense white matter in the elderly. AJNR 1995;16:253-258
21. McMorris A, McKinnon RD. Regulation of oligodendrocyte development and CNS myelination by growth factors: prospects for therapy of demyelinating diseases. Brain Pathol 1996; 6:313-329
22. Barnum SR. Complement biosynthesis in the central nervous system. Crit Rev Oral Biol Med 1995;6:132-146
23. Corsini E, Dufour A, Ciusani E, et al. Human brain endothelial cells and astrocytes produce IL-1 beta but not IL-10. Scand J Immunol 1996;44:506-511
24. De Groot CJ, Ruuls SR, Theeuwes JW, et al. Immunocytochemical characterization of the expression of inducible and constitutive isoforms of nitric oxide synthase in demyelinating multiple sclerosis lesions. J Neuropathol Exp Neurol 1997;56: 10-20
25. McKeown SR, Allen IV. The cellular origin of lysosomal enzymes in the plaque in multiple sclerosis: a combined histological and biochemical study. Neuropathol Appl Neurobiol 1978; 4:471-482
26. Cambi F, Lees MB, Williams RM, Macklin WB. Chronic experimental allergic encephalomyelitis produced by bovine proteolipid apoprotein: immunological studies in rabbits. Ann Neurol 1983;13:303-308
27. Dousset V, Brochet B, Gayou A, et al. Magnetization transfer profile of demyelinating CNS lesions. Proc Soc Magn Reson 1995;1:114 (Abstract)
28. Filippi M, Rocca MA, Rizzo G, et al. Magnetization transfer ratios in MS lesions enhancing after different doses of gadolinium. Neurology 1998 (In press)
29. Lexa FJ, Grossman RI, Rosenquist AC. MR of Wallerian degeneration in the feline visual system: characterization by magnetization transfer rate with histopathologic correlation. AJNR 1994;15:201-212
30. Dousset V, Brochet B, Vital A, et al. MR imaging including diffusion and magnetization transfer of chronic relapsing experimental encephalomyelitis: correlation with immunological and pathological data. Proc Soc Magn Reson 1994; 1:483 (Abstract)
31. Dousset V, Brochet B, Vital A, et al. Lysolecithin-induced demyelination in primates: preliminary in vivo study with MR and magnetization transfer. AJNR 1995;16:225-231
32. Thorpe JW, Barker GJ, Jones SJ, et al. Quantitative MRI in optic neuritis: correlation with clinical findings and electrophysiology. J Neurol Neurosurg Psychiatry 1995;59:487-492
33. Prineas JW, Barnard RO, Kwon EE, et al. Multiple sclerosis: remyelination of nascent lesions. Ann Neurol 1993;33:137-151
34. Lassman H, Suchanek G, Ozawa K. Histopathology and the blood-cerebrospinal fluid barrier in multiple sclerosis. Ann Neurol 1994;36(Suppl):S42-S46