T1-deficient and T1-Fc-transgenic mice develop a normal protective Th2-type immune response following infection with Nippostrongylus brasiliensis

European Journal of Immunology

Volumn 30, Issue 7, 2000, Pages 1929-1938

  Senn, Karin A ^a   McCoy, Kathy D ^b   Maloy, Kevin J ^b,d   Stark, Gerlinde ^c   Fröhli, Erika ^a   Rülicke, Thomas ^a   Klemenz, Roman ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b INSTITUTE OF EXPERIMENTAL IMMUNOLOGY   (Switzerland)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

Gene targeting; Nippostrongylus brasiliensis; T1 Th2 response; Transgenic

Indexed keywords

HYBRID PROTEIN; INTERLEUKIN 5;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELLULAR IMMUNODEFICIENCY; EOSINOPHIL; LYMPH NODE CELL; MOUSE; NEMATODIASIS; NIPPOSTRONGYLUS BRASILIENSIS; NONHUMAN; PARASITE IMMUNITY; PRIORITY JOURNAL; TH1 CELL; TH2 CELL; TRANSGENIC MOUSE;

ANIMALS; EOSINOPHILIA; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN GAMMA-CHAINS; INTERLEUKIN-5; KINETICS; LUNG; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NIPPOSTRONGYLUS; PROTEINS; RATS; RATS, INBRED LEW; RECEPTORS, CELL SURFACE; RECOMBINANT FUSION PROTEINS; STRONGYLIDA INFECTIONS; TH2 CELLS;

EID: 0033933919     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200007)30:7<1929::AID-IMMU1929>3.0.CO;2-1     Document Type: Article

References (30)

1. Yanagisawa, K., Naito, Y., Kuroiwa, K., Arai, T., Furukawa, Y., Tomizuka, H., Miura, Y., Kasahara, T. and Tominaga, S., The expression of ST2 gene in helper T cells and the binding of ST2 protein to myeloma-derived RPMI8226 cells. J. Biochem. Tokyo 1997. 121: 95-103.
2. Xu, D., Chan, W. L. and Leung, B. P., Huang, F., Wheeler, R., Piedrafita, D., Robinson, J. H. and Liew, F. Y., Selective expression of a stable surface molecule on type 2 but not type 1 helper T cell. J. Exp. Med. 1998. 187: 787-794.
3. Klemenz, R., Hoffmann, S. and Werenskiold, A. K., Serum- and oncoprotein-mediated induction of a gene with sequence similarity to the gene encoding carcinoembryonic antigen. Proc. Natl. Acad. Sci. USA 1989. 86: 5708-5712.
4. Lanahan, A., Williams, J. B., Sanders, L. K. and Nathans, D., Growth factor-induced delayed early response genes. Mol. Cell. Biol. 1992. 12: 3919-3929.
5. Bergers, G., Reikerstorfer, A., Braselmann, S., Graninger, P. and Busslinger, M., Alternative promoter usage of the Fosresponsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor. EMBO J 1994. 13: 1176-1188.
6. Tominaga, S., A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor. FEBS Lett. 1989. 258: 301-304.
7. Werenskiold, A. K., Hoffmann, S. and Klemenz, R., Induction of a mitogen-responsive gene after expression of the Ha-ras oncogene in NIH 3T3 fibroblasts. Mol. Cell. Biol. 1989. 9: 5207-5214.
8. Yanagisawa, K., Takagi, T., Tsukamoto, T., Tetsuka, T. and Tominaga, S., Presence of a novel primary response gene ST2L, encoding a product highly similar to the interleukin 1 receptor type 1 FEBS Lett. 1993. 318: 83-87.
9. Kumar, S., Minnich, M. D. and Young, P. R., ST2/T1 protein functionally binds to two secreted proteins from Balb/c 3T3 and human umbilical vein endothelial cells but does not bind interleukin 1., J. Biol. Chem. 1995. 270: 27905-27913.
10. Gayle, M. A., Slack, J. L., Bonnert, T. P., Renshaw, B. R., Sonoda, G., Taguchi, T., Testa, J. R., Dower, S. K. and Sims, J. E., Cloning of a putative ligand for the T1/ST2 receptor. J. Biol. Chem. 1996. 271: 5784-5789.
11. Reikerstorfer, A., Holz, H., Stunnenberg, H. G. and Busslinger, M., Low affinity binding of interleukin-1 beta and intracellular signaling via NF-kappa B identify Fit-1 as a distant member of the interleukin-1 receptor family. J. Biol. Chem. 1995. 270: 17645-17648.
12. Coyle, A. J., Lloyd, C., Tian, J., Nguyen, T., Erikkson, C., Wang, L., Ottoson, P., Persson, P., Delaney, T., Lehar, S., Lin, S., Poisson, L., Meisel, C., Kamradt, T., Bjerke, T., Levinson, D. and Gutierrez-Ramos, J. G., Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses. J. Exp. Med. 1999, 190: 895-902.
13. Coffman, R. L., Seymour, B. W., Hudak, S., Jackson, J. and Rennick, D., Antibody to interleukin-5 inhibits helminth-induced eosinophilia in mice. Science 1989. 245: 308-310.
14. Kopf, M., Le Gros, G., Bachmann, M., Lamers, M. C., Bluethmann, H. and Kohler, G., Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 1993. 362: 245-248.
15. Maizels, R. M. and Holland, M. J., Parasite immunology: pathways for expelling intestinal helminths. Curr. Biol. 1998. 8: R711-714.
16. Finkleman, F. D., Urban, J. F., Jr., Beckmann, M. P., Schooley, K. A., Holmes, J. M. and Katona, I. M., Regulation of murine in vivo IgG and IgE responses by a monoclonal anti-IL-4 receptor antibody. Int. Immunol. 1991. 3: 599-607.
17. Finkleman, F. D., Katona, I. M., Urban, J. F., Jr., Holmes, J., Ohara, J., Tung, A. S., Sample, J. V. and Paul, W. E., IL-4 is required to generate and sustain in vivo IgE responses. J. Immunol. 1988. 141: 2335-2341.
18. Finkleman, F. D., Madden, K. B., Cheever, A. W., Katona, I. M., Morris, S. C., Gately, M. K., Hubbard, B. R., Gause, W. C. and Urban, J. F., Jr., Effects of interleukin 12 on immune responses and host protection in mice infected with intestinal nematode parasites. J. Exp. Med. 1994. 179: 1563-1572.
19. McCoy, K., Cambens, M. and Le Gros, G., Protective immunity to nematode infection is induced by CTLA-4 blockade. J. Exp. Med. 1997. 186:183-187.
20. Urban, J. F., Jr., Madden, K. B., Svetic, A., Cheever, A., Trotta, P. R., Gause, W. C., Katona, I. M. and Finkelman, F. D., The importance of Th2 cytokines in protective immunity to nematodes. Immunol Rev. 1992. 127: 205-220.
21. Lohning, M., Stroehmann, A., Coyle, A. J., Grogan, J. L., Lin, S., Gutierrez Ramos, J. C., Levinson, D., Radbruch, A. and Kamradt, T., T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function. Proc. Natl. Acad. Sci. USA 1998. 95: 6930-6935.
22. Hoshino, K., Kashiwamura, S., Kuribayashi, K., Kodama, T., Tsujimura, T., Nakanishi, K., Matsuyama, T., Takeda, K. and Akira, S., The absence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector function. J. Exp. Med. 1999. 190: 1541-1548.
23. Moritz, D. R., Gheyselinck, J. and Klemenz, R., Expression analysis of the soluble and membrane-associated forms of the interleukin-1 receptor-related T1 protein in primary mast cells and fibroblast. Hybridoma 1998. 17: 107-116.
24. Garcia, I., Miyazaki, Y., Marchai, G., Lesslauer, W. and Vassalli, P., High sensitivity of transgenic mice expressing soluble TNFR1 fusion protein to mycobacterial infections: synergistic action of TNF and IFN-gamma in the differentiation of protective granulomas. Eur. J. Immunol. 1997. 27: 3182-3190.
25. Hogan, B., Beddington, R., Constantini, F. and Lacy, E., (Eds.) Manipulating the Mouse Embryo, A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Habor 1994.
26. Sambrook, T., Fritsch, E. F. and Maniatis, T. (Eds.) Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Habor 1989.
27. Kalousek, M. B., Trub, T., Schuermann, M. and Klemenz, R., T1 is a c-Fos- and FosB-responsive gene which is induced by growth factors through multiple signal transduction pathways, J. Biol. Chem. 1994. 269: 6866-6873.
28. Schumacher, J. H., O'Garra, A., Shrader, B., van Kimmenade, A., Bond, M. W., Mosmann., T. R. and Coffman, R. L., The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent. J. Immunol. 1988. 141: 1576-1581.
29. Ohara, J. and Paul, W. E., Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1. Nature 1985. 315: 333-336.
30. Prat, M., Gribaudo, G., Comoglio, P. M., Cavallo, G. and Landolfo, S., Monoclonal antibodies against murine gamma interferon. Proc. Natl. Acad. Sci. USA 1984. 81: 4515-4519.