메뉴 건너뛰기




Volumn 42, Issue 3, 2010, Pages 227-234

Mitochondrial bioenergetics and dynamics in Huntington's disease: Tripartite synapses and selective striatal degeneration

Author keywords

Astrocytes; Huntington's disease; Mitochondria; Neurons; Striatum

Indexed keywords

HUNTINGTIN;

EID: 77954426618     PISSN: 0145479X     EISSN: 15736881     Source Type: Journal    
DOI: 10.1007/s10863-010-9287-6     Document Type: Review
Times cited : (39)

References (58)
  • 1
    • 0033135292 scopus 로고    scopus 로고
    • Tripartite synapses: Glia, the unacknowledged partner
    • DOI 10.1016/S0166-2236(98)01349-6, PII S0166223698013496
    • A Araque V Parpura RP Sanzgiri PG Haydon 1999 Tripartite synapses: glia, the unacknowledged partner Trends Neurosci 22 208 215 10.1016/S0166-2236(98) 01349-6 1:CAS:528:DyaK1MXivVOktbg%3D (Pubitemid 29202082)
    • (1999) Trends in Neurosciences , vol.22 , Issue.5 , pp. 208-215
    • Araque, A.1    Parpura, V.2    Sanzgiri, R.P.3    Haydon, P.G.4
  • 2
    • 1542317747 scopus 로고    scopus 로고
    • Astrocyte Mitochondrial Mechanisms of Ischemic Brain Injury and Neuroprotection
    • DOI 10.1023/B:NERE.0000014830.06376.e6
    • L Bambrick T Kristian G Fiskum 2004 Astrocyte mitochondrial mechanisms of ischemic brain injury and neuroprotection Neurochem Res 29 601 608 10.1023/B:NERE.0000014830.06376.e6 1:CAS:528:DC%2BD2cXpslWisw%3D%3D (Pubitemid 38295010)
    • (2004) Neurochemical Research , vol.29 , Issue.3 , pp. 601-608
    • Bambrick, L.1    Kristian, T.2    Fiskum, G.3
  • 3
    • 33746081243 scopus 로고    scopus 로고
    • Cyclosporin A increases mitochondrial calcium uptake capacity in cortical astrocytes but not cerebellar granule neurons
    • DOI 10.1007/s10863-006-9004-7
    • LL Bambrick K Chandrasekaran Z Mehrabian C Wright BK Krueger G Fiskum 2006 Cyclosporin A increases mitochondrial calcium uptake capacity in cortical astrocytes but not cerebellar granule neurons J Bioenerg Biomembr 38 43 47 10.1007/s10863-006-9004-7 1:CAS:528:DC%2BD28XmvFeitro%3D (Pubitemid 44078518)
    • (2006) Journal of Bioenergetics and Biomembranes , vol.38 , Issue.1 , pp. 43-47
    • Bambrick, L.L.1    Chandrasekaran, K.2    Mehrabian, Z.3    Wright, C.4    Krueger, B.K.5    Fiskum, G.6
  • 4
    • 0033577870 scopus 로고    scopus 로고
    • 2+ waves in rat cortical astrocytes
    • DOI 10.1083/jcb.145.4.795
    • E Boitier R Rea MR Duchen 1999 Mitochondria exert a negative feedback on the propagation of intracellular Ca2+ waves in rat cortical astrocytes J Cell Biol 145 795 808 10.1083/jcb.145.4.795 1:CAS:528:DyaK1MXjt1Wgsb4%3D (Pubitemid 29240856)
    • (1999) Journal of Cell Biology , vol.145 , Issue.4 , pp. 795-808
    • Boitier, E.1    Rea, R.2    Duchen, M.R.3
  • 5
    • 76049118058 scopus 로고    scopus 로고
    • Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms
    • 10.1073/pnas.0911503106 1:CAS:528:DC%2BC3cXmsVaisA%3D%3D
    • J Bradford JY Shin M Roberts CE Wang XJ Li S Li 2009 Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms Proc Natl Acad Sci U S A 106 22480 22485 10.1073/pnas.0911503106 1:CAS:528:DC%2BC3cXmsVaisA%3D%3D
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 22480-22485
    • Bradford, J.1    Shin, J.Y.2    Roberts, M.3    Wang, C.E.4    Li, X.J.5    Li, S.6
  • 6
    • 77951238141 scopus 로고    scopus 로고
    • Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice
    • 10.1074/jbc.M109.083287
    • J Bradford JY Shin M Roberts CE Wang G Sheng S Li XJ Li 2010 Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice J Biol Chem 10.1074/jbc.M109.083287
    • (2010) J Biol Chem
    • Bradford, J.1    Shin, J.Y.2    Roberts, M.3    Wang, C.E.4    Sheng, G.5    Li, S.6    Li, X.J.7
  • 7
    • 29144468251 scopus 로고    scopus 로고
    • 3-Nitropropionic acid: A mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease
    • DOI 10.1111/j.1471-4159.2005.03515.x
    • E Brouillet C Jacquard N Bizat D Blum 2005 3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease J Neurochem 95 1521 1540 10.1111/j.1471-4159.2005.03515.x 1:CAS:528:DC%2BD28XhsVKjtQ%3D%3D (Pubitemid 41804051)
    • (2005) Journal of Neurochemistry , vol.95 , Issue.6 , pp. 1521-1540
    • Brouillet, E.1    Jacquard, C.2    Bizat, N.3    Blum, D.4
  • 8
    • 33744964144 scopus 로고    scopus 로고
    • 2+ overload than nonsynaptic mitochondria
    • DOI 10.1074/jbc.M510303200
    • MR Brown PG Sullivan JW Geddes 2006 Synaptic mitochondria are more susceptible to Ca2+overload than nonsynaptic mitochondria J Biol Chem 281 11658 11668 10.1074/jbc.M510303200 1:CAS:528:DC%2BD28Xjslegur0%3D (Pubitemid 43855423)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.17 , pp. 11658-11668
    • Brown, M.R.1    Sullivan, P.G.2    Geddes, J.W.3
  • 9
    • 57649187103 scopus 로고    scopus 로고
    • Mitochondria and Huntington's disease pathogenesis: Insight from genetic and chemical models
    • 1:CAS:528:DC%2BD1MXhsVaqu7Y%3D
    • SE Browne 2008 Mitochondria and Huntington's disease pathogenesis: insight from genetic and chemical models Ann N Y Acad Sci 1147 358 382 1:CAS:528:DC%2BD1MXhsVaqu7Y%3D
    • (2008) Ann N y Acad Sci , vol.1147 , pp. 358-382
    • Browne, S.E.1
  • 10
    • 0037741021 scopus 로고    scopus 로고
    • Increased susceptibility of striatal mitochondria to calcium-induced permeability transition
    • 1:CAS:528:DC%2BD3sXltlensb8%3D
    • N Brustovetsky T Brustovetsky KJ Purl M Capano M Crompton JM Dubinsky 2003 Increased susceptibility of striatal mitochondria to calcium-induced permeability transition J Neurosci 23 4858 4867 1:CAS:528:DC%2BD3sXltlensb8%3D
    • (2003) J Neurosci , vol.23 , pp. 4858-4867
    • Brustovetsky, N.1    Brustovetsky, T.2    Purl, K.J.3    Capano, M.4    Crompton, M.5    Dubinsky, J.M.6
  • 11
    • 20744433946 scopus 로고    scopus 로고
    • Age-dependent changes in the calcium sensitivity of striatal mitochondria in mouse models of Huntington's disease
    • DOI 10.1111/j.1471-4159.2005.03036.x
    • N Brustovetsky R LaFrance KJ Purl T Brustovetsky CD Keene WC Low JM Dubinsky 2005 Age-dependent changes in the calcium sensitivity of striatal mitochondria in mouse models of Huntington's Disease J Neurochem 93 1361 1370 10.1111/j.1471-4159.2005.03036.x 1:CAS:528:DC%2BD2MXlsFemsrs%3D (Pubitemid 40853259)
    • (2005) Journal of Neurochemistry , vol.93 , Issue.6 , pp. 1361-1370
    • Brustovetsky, N.1    LaFrance, R.2    Purl, K.J.3    Brustovetsky, T.4    Keene, C.D.5    Low, W.C.6    Dubinsky, J.M.7
  • 12
    • 0034649379 scopus 로고    scopus 로고
    • Cellular factors controlling neuronal vulnerability in the brain: A lesson from the striatum
    • 1:CAS:528:DC%2BD3cXos12gt7c%3D
    • P Calabresi D Centonze G Bernardi 2000 Cellular factors controlling neuronal vulnerability in the brain: a lesson from the striatum Neurology 55 1249 1255 1:CAS:528:DC%2BD3cXos12gt7c%3D
    • (2000) Neurology , vol.55 , pp. 1249-1255
    • Calabresi, P.1    Centonze, D.2    Bernardi, G.3
  • 13
    • 0038143180 scopus 로고    scopus 로고
    • The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria
    • DOI 10.1074/jbc.M212661200
    • S Chalmers DG Nicholls 2003 The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria J Biol Chem 278 19062 19070 10.1074/jbc.M212661200 1:CAS:528:DC%2BD3sXjvVSks7o%3D (Pubitemid 36799293)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.21 , pp. 19062-19070
    • Chalmers, S.1    Nicholls, D.G.2
  • 14
    • 33845927357 scopus 로고    scopus 로고
    • Mitochondrial trafficking and morphology in healthy and injured neurons
    • DOI 10.1016/j.pneurobio.2006.09.003, PII S0301008206001109
    • DT Chang IJ Reynolds 2006 Mitochondrial trafficking and morphology in healthy and injured neurons Prog Neurobiol 80 241 268 10.1016/j.pneurobio.2006. 09.003 1:CAS:528:DC%2BD2sXit12rtQ%3D%3D (Pubitemid 46028946)
    • (2006) Progress in Neurobiology , vol.80 , Issue.5 , pp. 241-268
    • Chang, D.T.W.1    Reynolds, I.J.2
  • 15
    • 33646136884 scopus 로고    scopus 로고
    • Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons
    • 10.1016/j.nbd.2005.12.007 1:CAS:528:DC%2BD28XktVyjs7o%3D
    • DT Chang GL Rintoul S Pandipati IJ Reynolds 2006 Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons Neurobiol Dis 22 388 400 10.1016/j.nbd.2005.12.007 1:CAS:528: DC%2BD28XktVyjs7o%3D
    • (2006) Neurobiol Dis , vol.22 , pp. 388-400
    • Chang, D.T.1    Rintoul, G.L.2    Pandipati, S.3    Reynolds, I.J.4
  • 16
    • 77951096150 scopus 로고    scopus 로고
    • Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
    • 10.1093/hmg/ddp326 1:CAS:528:DC%2BD1MXhtlCqu7nN
    • H Chen DC Chan 2009 Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases Hum Mol Genet 18 R169 R176 10.1093/hmg/ddp326 1:CAS:528:DC%2BD1MXhtlCqu7nN
    • (2009) Hum Mol Genet , vol.18
    • Chen, H.1    Chan, D.C.2
  • 17
    • 3543141113 scopus 로고    scopus 로고
    • Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release
    • DOI 10.1093/hmg/ddh162
    • YS Choo GV Johnson M MacDonald PJ Detloff M Lesort 2004 Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release Hum Mol Genet 13 1407 1420 10.1093/hmg/ddh162 1:CAS:528:DC%2BD2cXlt1WlsL4%3D (Pubitemid 39023049)
    • (2004) Human Molecular Genetics , vol.13 , Issue.14 , pp. 1407-1420
    • Choo, Y.S.1    Johnson, G.V.W.2    MacDonald, M.3    Detloff, P.J.4    Lesort, M.5
  • 18
    • 70350018325 scopus 로고    scopus 로고
    • Multiple roles of HDAC inhibition in neurodegenerative conditions
    • 10.1016/j.tins.2009.06.002 1:CAS:528:DC%2BD1MXhtlWisLnN
    • DM Chuang Y Leng Z Marinova HJ Kim CT Chiu 2009 Multiple roles of HDAC inhibition in neurodegenerative conditions Trends Neurosci 32 591 601 10.1016/j.tins.2009.06.002 1:CAS:528:DC%2BD1MXhtlWisLnN
    • (2009) Trends Neurosci , vol.32 , pp. 591-601
    • Chuang, D.M.1    Leng, Y.2    Marinova, Z.3    Kim, H.J.4    Chiu, C.T.5
  • 19
    • 20344364186 scopus 로고    scopus 로고
    • Astrocytic contributions to bioenergetics of cerebral ischemia
    • DOI 10.1002/glia.20157
    • GA Dienel L Hertz 2005 Astrocytic contributions to bioenergetics of cerebral ischemia Glia 50 362 388 10.1002/glia.20157 (Pubitemid 40780841)
    • (2005) GLIA , vol.50 , Issue.4 , pp. 362-388
    • Dienel, G.A.1    Hertz, L.2
  • 21
    • 34248172476 scopus 로고    scopus 로고
    • Toxicity of β-amyloid in HEK293 cells expressing NR1/NR2A or NR1/NR2B N-methyl-d-aspartate receptor subunits
    • DOI 10.1016/j.neuint.2007.03.001, PII S0197018607000605
    • A Domingues S Almeida EF da Cruz e Silva CR Oliveira AC Rego 2007 Toxicity of beta-amyloid in HEK293 cells expressing NR1/NR2A or NR1/NR2B N-methyl-D-aspartate receptor subunits Neurochem Int 50 872 880 10.1016/j.neuint.2007.03.001 1:CAS:528:DC%2BD2sXltF2ls7s%3D (Pubitemid 46710199)
    • (2007) Neurochemistry International , vol.50 , Issue.6 , pp. 872-880
    • Domingues, A.1    Almeida, S.2    Da Cruz E Silva, E.F.3    Oliveira, C.R.4    Rego, A.C.5
  • 22
    • 0346749473 scopus 로고    scopus 로고
    • Enhanced Akt Signaling Is an Early Pro-survival Response That Reflects N-Methyl-D-aspartate Receptor Activation in Huntington's Disease Knock-in Striatal Cells
    • DOI 10.1074/jbc.M309348200
    • S Gines E Ivanova IS Seong CA Saura ME MacDonald 2003 Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells J Biol Chem 278 50514 50522 10.1074/jbc.M309348200 1:CAS:528:DC%2BD3sXpslSqtLc%3D (Pubitemid 37548897)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.50 , pp. 50514-50522
    • Gines, S.1    Ivanova, E.2    Seong, I.-S.3    Saura, C.A.4    MacDonald, M.E.5
  • 23
    • 0017839485 scopus 로고
    • Juvenile Huntington chorea: Clinical, ultrastructural, and biochemical studies
    • 1:CAS:528:DyaE1cXhtVaqt7Y%3D
    • HH Goebel R Heipertz W Scholz K Iqbal I Tellez-Nagel 1978 Juvenile Huntington chorea: clinical, ultrastructural, and biochemical studies Neurology 28 23 31 1:CAS:528:DyaE1cXhtVaqt7Y%3D
    • (1978) Neurology , vol.28 , pp. 23-31
    • Goebel, H.H.1    Heipertz, R.2    Scholz, W.3    Iqbal, K.4    Tellez-Nagel, I.5
  • 24
    • 0029875381 scopus 로고    scopus 로고
    • Mitochondrial defect in Huntington's disease caudate nucleus
    • DOI 10.1002/ana.410390317
    • M Gu MT Gash VM Mann F Javoy-Agid JM Cooper AH Schapira 1996 Mitochondrial defect in Huntington's disease caudate nucleus Ann Neurol 39 385 389 10.1002/ana.410390317 1:CAS:528:DyaK28XisFyrsbo%3D (Pubitemid 26100764)
    • (1996) Annals of Neurology , vol.39 , Issue.3 , pp. 385-389
    • Gu, M.1    Gash, M.T.2    Mann, V.M.3    Javoy-Agid, F.4    Cooper, J.M.5    Schapira, A.H.V.6
  • 25
    • 0034329159 scopus 로고    scopus 로고
    • Molecular genetics: Unmasking polyglutamine triggers in neurodegenerative disease
    • 10.1038/35039051 1:CAS:528:DC%2BD3MXivVSitLo%3D
    • JF Gusella ME MacDonald 2000 Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease Nat Rev Neurosci 1 109 115 10.1038/35039051 1:CAS:528:DC%2BD3MXivVSitLo%3D
    • (2000) Nat Rev Neurosci , vol.1 , pp. 109-115
    • Gusella, J.F.1    MacDonald, M.E.2
  • 26
    • 77955089391 scopus 로고    scopus 로고
    • Targeting glial cells to elucidate the pathogenesis of Huntington's disease
    • 10.1007/s12035-009-8097-5
    • HY Hsiao Y Chern 2010 Targeting glial cells to elucidate the pathogenesis of Huntington's disease Mol Neurobiol 10.1007/s12035-009-8097-5
    • (2010) Mol Neurobiol
    • Hsiao, H.Y.1    Chern, Y.2
  • 27
    • 74049164709 scopus 로고    scopus 로고
    • Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
    • 10.1083/jcb.200908164 1:CAS:528:DC%2BD1MXhsF2qtb3F
    • H Ilieva M Polymenidou DW Cleveland 2009 Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond J Cell Biol 187 761 772 10.1083/jcb.200908164 1:CAS:528:DC%2BD1MXhsF2qtb3F
    • (2009) J Cell Biol , vol.187 , pp. 761-772
    • Ilieva, H.1    Polymenidou, M.2    Cleveland, D.W.3
  • 28
    • 3543030406 scopus 로고    scopus 로고
    • In Situ respiration and bioenergetic status of mitochondria in primary cerebellar granule neuronal cultures exposed continuously to glutamate
    • DOI 10.1074/jbc.M401540200
    • MB Jekabsons DG Nicholls 2004 In situ respiration and bioenergetic status of mitochondria in primary cerebellar granule neuronal cultures exposed continuously to glutamate J Biol Chem 279 32989 33000 10.1074/jbc.M401540200 1:CAS:528:DC%2BD2cXmtVChu7g%3D (Pubitemid 39014759)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.31 , pp. 32989-33000
    • Jekabsons, M.B.1    Nicholls, D.G.2
  • 29
    • 33847043933 scopus 로고    scopus 로고
    • Mitochondria and neuronal activity
    • 10.1152/ajpcell.00222.2006 1:CAS:528:DC%2BD2sXjt1Gmtb4%3D
    • O Kann R Kovacs 2007 Mitochondria and neuronal activity Am J Physiol Cell Physiol 292 C641 C657 10.1152/ajpcell.00222.2006 1:CAS:528:DC%2BD2sXjt1Gmtb4%3D
    • (2007) Am J Physiol Cell Physiol , vol.292
    • Kann, O.1    Kovacs, R.2
  • 30
    • 53249130741 scopus 로고    scopus 로고
    • Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
    • 10.1038/nrd2681 1:CAS:528:DC%2BD1cXhtFOlu7rK
    • AG Kazantsev LM Thompson 2008 Therapeutic application of histone deacetylase inhibitors for central nervous system disorders Nat Rev Drug Discov 7 854 868 10.1038/nrd2681 1:CAS:528:DC%2BD1cXhtFOlu7rK
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 854-868
    • Kazantsev, A.G.1    Thompson, L.M.2
  • 32
    • 0034597411 scopus 로고    scopus 로고
    • Cyclosporin A protects striatal neurons in vitro and in vivo from 3-nitropropionic acid toxicity
    • 10.1002/1096-9861(20001002)425:4<471::AID-CNE1>3.0.CO;2-U 1:CAS:528:DC%2BD3cXmvVWms7o%3D
    • L Leventhal CE Sortwell R Hanbury TJ Collier JH Kordower S Palfi 2000 Cyclosporin A protects striatal neurons in vitro and in vivo from 3-nitropropionic acid toxicity J Comp Neurol 425 471 478 10.1002/1096- 9861(20001002)425:4<471::AID-CNE1>3.0.CO;2-U 1:CAS:528: DC%2BD3cXmvVWms7o%3D
    • (2000) J Comp Neurol , vol.425 , pp. 471-478
    • Leventhal, L.1    Sortwell, C.E.2    Hanbury, R.3    Collier, T.J.4    Kordower, J.H.5    Palfi, S.6
  • 33
    • 35548957787 scopus 로고    scopus 로고
    • Astrocytes in Huntington's chorea: Accomplice or guilty of the neuronal death?
    • JC Lievens S Birman 2007 Astrocytes in Huntington's chorea: accomplice or guilty of the neuronal death? Med Sci (Paris) 23 845 849
    • (2007) Med Sci (Paris) , vol.23 , pp. 845-849
    • Lievens, J.C.1    Birman, S.2
  • 34
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • DOI 10.1038/nature05292, PII NATURE05292
    • MT Lin MF Beal 2006 Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases Nature 443 787 795 10.1038/nature05292 1:CAS:528:DC%2BD28XhtVyktbbO (Pubitemid 44622683)
    • (2006) Nature , vol.443 , Issue.7113 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 35
    • 67349120572 scopus 로고    scopus 로고
    • Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA- and ROS-dependent pathway
    • 10.1038/cdd.2009.22 1:CAS:528:DC%2BD1MXlvV2gtLo%3D
    • G Liot B Bossy S Lubitz Y Kushnareva N Sejbuk E Bossy-Wetzel 2009 Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA- and ROS-dependent pathway Cell Death Differ 16 899 909 10.1038/cdd.2009.22 1:CAS:528:DC%2BD1MXlvV2gtLo%3D
    • (2009) Cell Death Differ , vol.16 , pp. 899-909
    • Liot, G.1    Bossy, B.2    Lubitz, S.3    Kushnareva, Y.4    Sejbuk, N.5    Bossy-Wetzel, E.6
  • 36
    • 35549006420 scopus 로고    scopus 로고
    • Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease
    • DOI 10.1038/nn1988, PII NN1988
    • CS Lobsiger DW Cleveland 2007 Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease Nat Neurosci 10 1355 1360 10.1038/nn1988 1:CAS:528:DC%2BD2sXht1ajsbfF (Pubitemid 350014678)
    • (2007) Nature Neuroscience , vol.10 , Issue.11 , pp. 1355-1360
    • Lobsiger, C.S.1    Cleveland, D.W.2
  • 37
    • 70349096650 scopus 로고    scopus 로고
    • Biochemical, molecular and epigenetic mechanisms of valproic acid neuroprotection
    • 10.2174/1874467210902010095 1:CAS:528:DC%2BD1MXkvVSgt70%3D
    • B Monti E Polazzi A Contestabile 2009 Biochemical, molecular and epigenetic mechanisms of valproic acid neuroprotection Curr Mol Pharmacol 2 95 109 10.2174/1874467210902010095 1:CAS:528:DC%2BD1MXkvVSgt70%3D
    • (2009) Curr Mol Pharmacol , vol.2 , pp. 95-109
    • Monti, B.1    Polazzi, E.2    Contestabile, A.3
  • 38
    • 77953302472 scopus 로고    scopus 로고
    • Nature and cause of mitochondrial dysfunction in Huntington's disease: Focusing on Huntingtin and the Striatum
    • doi: 10.1111/j.1471-4159.2010.06741.x
    • Oliveira JM (2010a) Nature and cause of mitochondrial dysfunction in Huntington's disease: focusing on Huntingtin and the Striatum. J Neurochem doi: 10.1111/j.1471-4159.2010.06741.x
    • (2010) J Neurochem
    • Oliveira, J.M.1
  • 39
    • 77953298993 scopus 로고    scopus 로고
    • Techniques to investigate neuronal mitochondrial function and its pharmacological modulation
    • Accepted for publication
    • Oliveira JM (2010b) Techniques to investigate neuronal mitochondrial function and its pharmacological modulation. Curr Drug Targets. Accepted for publication
    • (2010) Curr Drug Targets
    • Oliveira, J.M.1
  • 40
    • 64149094332 scopus 로고    scopus 로고
    • In situ mitochondrial Ca2+ buffering differences of intact neurons and astrocytes from cortex and striatum
    • 10.1074/jbc.M807459200 1:CAS:528:DC%2BD1MXhvVSns7c%3D
    • JM Oliveira J Gonçalves 2009 In situ mitochondrial Ca2+ buffering differences of intact neurons and astrocytes from cortex and striatum J Biol Chem 284 5010 5020 10.1074/jbc.M807459200 1:CAS:528:DC%2BD1MXhvVSns7c%3D
    • (2009) J Biol Chem , vol.284 , pp. 5010-5020
    • Oliveira, J.M.1    Gonçalves, J.2
  • 41
    • 77953307283 scopus 로고    scopus 로고
    • Neuronal and astrocytic mitochondrial dynamics as vulnerability factors and targets for neuroprotection [Abstract]
    • 10.3389/conf.neuro.01.2009.11.041
    • JM Oliveira J Gonçalves 2009 Neuronal and astrocytic mitochondrial dynamics as vulnerability factors and targets for neuroprotection [Abstract] Frontiers Neurosci 10.3389/conf.neuro.01.2009.11.041
    • (2009) Frontiers Neurosci
    • Oliveira, J.M.1    Gonçalves, J.2
  • 44
    • 33947200596 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in Huntington's disease: The bioenergetics of isolated and in situ mitochondria from transgenic mice
    • DOI 10.1111/j.1471-4159.2006.04361.x
    • JM Oliveira MB Jekabsons S Chen A Lin AC Rego J Gonçalves LM Ellerby DG Nicholls 2007 Mitochondrial dysfunction in Huntington's disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice J Neurochem 101 241 249 10.1111/j.1471-4159.2006.04361.x 1:CAS:528: DC%2BD2sXksFSqtro%3D (Pubitemid 46426480)
    • (2007) Journal of Neurochemistry , vol.101 , Issue.1 , pp. 241-249
    • Oliveira, J.M.A.1    Jekabsons, M.B.2    Chen, S.3    Lin, A.4    Rego, A.C.5    Goncalves, J.6    Ellerby, L.M.7    Nicholls, D.G.8
  • 47
    • 68049143450 scopus 로고    scopus 로고
    • Tripartite synapses: Astrocytes process and control synaptic information
    • 10.1016/j.tins.2009.05.001 1:CAS:528:DC%2BD1MXps1aju7Y%3D
    • G Perea M Navarrete A Araque 2009 Tripartite synapses: astrocytes process and control synaptic information Trends Neurosci 32 421 431 10.1016/j.tins.2009.05.001 1:CAS:528:DC%2BD1MXps1aju7Y%3D
    • (2009) Trends Neurosci , vol.32 , pp. 421-431
    • Perea, G.1    Navarrete, M.2    Araque, A.3
  • 48
    • 55749098984 scopus 로고    scopus 로고
    • Mitochondria modulate Ca2+-dependent glutamate release from rat cortical astrocytes
    • 10.1523/JNEUROSCI.3484-08.2008 1:CAS:528:DC%2BD1cXht1SnsrnP
    • RC Reyes V Parpura 2008 Mitochondria modulate Ca2+-dependent glutamate release from rat cortical astrocytes J Neurosci 28 9682 9691 10.1523/JNEUROSCI.3484-08.2008 1:CAS:528:DC%2BD1cXht1SnsrnP
    • (2008) J Neurosci , vol.28 , pp. 9682-9691
    • Reyes, R.C.1    Parpura, V.2
  • 49
    • 10244241835 scopus 로고    scopus 로고
    • Mitochondrial trafficking in neurons: A key variable in neurodegeneration?
    • DOI 10.1023/B:JOBB.0000041754.78313.c2
    • IJ Reynolds LM Malaiyandi M Coash GL Rintoul 2004 Mitochondrial trafficking in neurons: a key variable in neurodegeneration? J Bioenerg Biomembr 36 283 286 10.1023/B:JOBB.0000041754.78313.c2 1:CAS:528:DC%2BD2cXnsFyis7Y%3D (Pubitemid 39619827)
    • (2004) Journal of Bioenergetics and Biomembranes , vol.36 , Issue.4 SPEC.ISS. , pp. 283-286
    • Reynolds, I.J.1    Malaiyandi, L.M.2    Coash, M.3    Rintoul, G.L.4
  • 50
    • 0041819756 scopus 로고    scopus 로고
    • Glutamate decreases mitochondrial size and movement in primary forebrain neurons
    • 1:CAS:528:DC%2BD3sXmvFGhurg%3D
    • GL Rintoul AJ Filiano JB Brocard GJ Kress IJ Reynolds 2003 Glutamate decreases mitochondrial size and movement in primary forebrain neurons J Neurosci 23 7881 7888 1:CAS:528:DC%2BD3sXmvFGhurg%3D
    • (2003) J Neurosci , vol.23 , pp. 7881-7888
    • Rintoul, G.L.1    Filiano, A.J.2    Brocard, J.B.3    Kress, G.J.4    Reynolds, I.J.5
  • 51
    • 35548957889 scopus 로고    scopus 로고
    • Astrocyte metabolism and signaling during brain ischemia
    • DOI 10.1038/nn2004, PII NN2004
    • DJ Rossi JD Brady C Mohr 2007 Astrocyte metabolism and signaling during brain ischemia Nat Neurosci 10 1377 1386 10.1038/nn2004 1:CAS:528: DC%2BD2sXht1ajsbnE (Pubitemid 350014689)
    • (2007) Nature Neuroscience , vol.10 , Issue.11 , pp. 1377-1386
    • Rossi, D.J.1    Brady, J.D.2    Mohr, C.3
  • 52
    • 29144460321 scopus 로고    scopus 로고
    • Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity
    • DOI 10.1083/jcb.200508072
    • JY Shin ZH Fang ZX Yu CE Wang SH Li XJ Li 2005 Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity J Cell Biol 171 1001 1012 10.1083/jcb.200508072 1:CAS:528:DC%2BD2MXhtlequ7fF (Pubitemid 41815832)
    • (2005) Journal of Cell Biology , vol.171 , Issue.6 , pp. 1001-1012
    • Shin, J.-Y.1    Fang, Z.-H.2    Yu, Z.-X.3    Wang, C.-E.4    Li, S.-H.5    Li, X.-J.6
  • 53
    • 31544447731 scopus 로고    scopus 로고
    • Juvenile Huntington's disease: Does a dosage-effect pathogenic mechanism differ from the classical adult disease?
    • DOI 10.1016/j.mad.2005.09.012, PII S0047637405002307, Dementias and Cognitive Sidorders: New Insights and Approaches
    • F Squitieri L Frati A Ciarmiello S Lastoria O Quarrell 2006 Juvenile Huntington's disease: does a dosage-effect pathogenic mechanism differ from the classical adult disease? Mech Ageing Dev 127 208 212 10.1016/j.mad.2005.09.012 (Pubitemid 43165620)
    • (2006) Mechanisms of Ageing and Development , vol.127 , Issue.2 , pp. 208-212
    • Squitieri, F.1    Frati, L.2    Ciarmiello, A.3    Lastoria, S.4    Quarrell, O.5
  • 54
    • 0034571171 scopus 로고    scopus 로고
    • Huntington's disease: The challenge for cell biologists
    • 10.1016/S0962-8924(00)01853-5 1:CAS:528:DC%2BD3cXot12ltLo%3D
    • AJ Tobin ER Signer 2000 Huntington's disease: the challenge for cell biologists Trends Cell Biol 10 531 536 10.1016/S0962-8924(00)01853-5 1:CAS:528:DC%2BD3cXot12ltLo%3D
    • (2000) Trends Cell Biol , vol.10 , pp. 531-536
    • Tobin, A.J.1    Signer, E.R.2
  • 56
    • 49349102894 scopus 로고    scopus 로고
    • Mitochondrial fusion, fission and autophagy as a quality control axis: The bioenergetic view
    • 10.1016/j.bbabio.2008.05.001 1:CAS:528:DC%2BD1cXpvF2qt7g%3D
    • G Twig B Hyde OS Shirihai 2008 Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view Biochim Biophys Acta 1777 1092 1097 10.1016/j.bbabio.2008.05.001 1:CAS:528:DC%2BD1cXpvF2qt7g%3D
    • (2008) Biochim Biophys Acta , vol.1777 , pp. 1092-1097
    • Twig, G.1    Hyde, B.2    Shirihai, O.S.3
  • 57
    • 58949099388 scopus 로고    scopus 로고
    • Effects of overexpression of huntingtin proteins on mitochondrial integrity
    • 10.1093/hmg/ddn404 1:CAS:528:DC%2BD1MXhtVWjsbs%3D
    • H Wang PJ Lim M Karbowski MJ Monteiro 2009 Effects of overexpression of huntingtin proteins on mitochondrial integrity Hum Mol Genet 18 737 752 10.1093/hmg/ddn404 1:CAS:528:DC%2BD1MXhtVWjsbs%3D
    • (2009) Hum Mol Genet , vol.18 , pp. 737-752
    • Wang, H.1    Lim, P.J.2    Karbowski, M.3    Monteiro, M.J.4
  • 58
    • 64349099993 scopus 로고    scopus 로고
    • The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease
    • 10.1111/j.1471-4159.2009.05867.x 1:CAS:528:DC%2BD1MXlsFyksbk%3D
    • X Wang B Su L Zheng G Perry MA Smith X Zhu 2009 The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease J Neurochem 109 Suppl 1 153 159 10.1111/j.1471-4159.2009.05867.x 1:CAS:528: DC%2BD1MXlsFyksbk%3D
    • (2009) J Neurochem , vol.109 , Issue.SUPPL. 1 , pp. 153-159
    • Wang, X.1    Su, B.2    Zheng, L.3    Perry, G.4    Smith, M.A.5    Zhu, X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.