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Volumn 21, Issue 7, 2010, Pages 419-427

Clinical, genetic and molecular characterization of patients with familial isolated pituitary adenomas (FIPA)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUCOCORTICOID RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; HEAT SHOCK PROTEIN 90; HEPATITIS B VIRUS X PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHODIESTERASE; SURVIVIN; THYROID HORMONE RECEPTOR BETA; TUMOR SUPPRESSOR PROTEIN; VIRUS PROTEIN; ARYL HYDROCARBON RECEPTOR-INTERACTING PROTEIN; SIGNAL PEPTIDE;

EID: 77954316421     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tem.2010.02.007     Document Type: Review
Times cited : (96)

References (92)
  • 1
    • 35548967589 scopus 로고    scopus 로고
    • The clinical, pathological, and genetic features of familial isolated pituitary adenomas
    • Beckers A., Daly A.F. The clinical, pathological, and genetic features of familial isolated pituitary adenomas. Eur. J. Endocrinol. 2007, 157:371-382.
    • (2007) Eur. J. Endocrinol. , vol.157 , pp. 371-382
    • Beckers, A.1    Daly, A.F.2
  • 2
    • 0032927318 scopus 로고    scopus 로고
    • Loss of heterozygosity on chromosome 11q13 in two families with acromegaly/gigantism is independent of mutations of the multiple endocrine neoplasia type I gene
    • Gadelha M.R., et al. Loss of heterozygosity on chromosome 11q13 in two families with acromegaly/gigantism is independent of mutations of the multiple endocrine neoplasia type I gene. J. Clin. Endocrinol. Metab. 1999, 84:249-256.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 249-256
    • Gadelha, M.R.1
  • 3
    • 0031023171 scopus 로고    scopus 로고
    • Inactivation of the tumor suppressor gene on 11q13 in brothers with familial acrogigantism without multiple endocrine neoplasia type 1
    • Yamada S., et al. Inactivation of the tumor suppressor gene on 11q13 in brothers with familial acrogigantism without multiple endocrine neoplasia type 1. J. Clin. Endocrinol. Metab. 1997, 82:239-242.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 239-242
    • Yamada, S.1
  • 4
    • 77954314879 scopus 로고    scopus 로고
    • Familial isolated pituitary adenomas not related to the MEN-1 syndrome: A study of 27 patients. 10th Meeting of the Belgian Endocrine Society. (abstract)
    • Valdes-Socin, H. et al. (2000) Familial isolated pituitary adenomas not related to the MEN-1 syndrome: A study of 27 patients. 10th Meeting of the Belgian Endocrine Society. (abstract).
    • (2000)
    • Valdes-Socin, H.1
  • 5
    • 33748742372 scopus 로고    scopus 로고
    • Clinical characterization of familial isolated pituitary adenomas
    • Daly A.F., et al. Clinical characterization of familial isolated pituitary adenomas. J. Clin. Endocrinol. Metab. 2006, 91:3316-3323.
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 3316-3323
    • Daly, A.F.1
  • 6
    • 33744486595 scopus 로고    scopus 로고
    • Pituitary adenoma predisposition caused by germline mutations in the AIP gene
    • Vierimaa O., et al. Pituitary adenoma predisposition caused by germline mutations in the AIP gene. Science 2006, 312:1228-1230.
    • (2006) Science , vol.312 , pp. 1228-1230
    • Vierimaa, O.1
  • 7
    • 34249844835 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families
    • Daly A.F., et al. Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families. J. Clin. Endocrinol. Metab. 2007, 92:1891-1896.
    • (2007) J. Clin. Endocrinol. Metab. , vol.92 , pp. 1891-1896
    • Daly, A.F.1
  • 8
    • 45149085453 scopus 로고    scopus 로고
    • The role of the AIP gene in familial and sporadic pituitary adenomas
    • Leontiou C.A., et al. The role of the AIP gene in familial and sporadic pituitary adenomas. J. Clin. Endocrinol. Metab. 2008, 93:2390-2401.
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 2390-2401
    • Leontiou, C.A.1
  • 9
    • 28744458910 scopus 로고    scopus 로고
    • Tumor deletion mapping on chromosome 11q13 in eight families with isolated familial somatotropinoma and in 15 sporadic somatotropinomas
    • Soares B.S., et al. Tumor deletion mapping on chromosome 11q13 in eight families with isolated familial somatotropinoma and in 15 sporadic somatotropinomas. J. Clin. Endocrinol. Metab. 2005, 90:6580-6587.
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 6580-6587
    • Soares, B.S.1
  • 10
    • 0034453781 scopus 로고    scopus 로고
    • Isolated familial somatotropinomas: establishment of linkage to chromosome 11q13.1-11q13.3 and evidence for a potential second locus at chromosome 2p16-12
    • Gadelha M.R., et al. Isolated familial somatotropinomas: establishment of linkage to chromosome 11q13.1-11q13.3 and evidence for a potential second locus at chromosome 2p16-12. J. Clin. Endocrinol. Metab. 2000, 85:707-714.
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 707-714
    • Gadelha, M.R.1
  • 11
    • 0037145025 scopus 로고    scopus 로고
    • The role of chaperone proteins in the aryl hydrocarbon receptor core complex
    • Petrulis J.R., Perdew G.H. The role of chaperone proteins in the aryl hydrocarbon receptor core complex. Chem. Biol. Interact. 2002, 141:25-40.
    • (2002) Chem. Biol. Interact. , vol.141 , pp. 25-40
    • Petrulis, J.R.1    Perdew, G.H.2
  • 13
    • 0029803550 scopus 로고    scopus 로고
    • XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivation
    • Kuzhandaivelu N., et al. XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivation. Nucleic Acids Res. 1996, 24:4741-4750.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4741-4750
    • Kuzhandaivelu, N.1
  • 14
    • 34247180053 scopus 로고    scopus 로고
    • Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations
    • Georgitsi M., et al. Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:4101-4105.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 4101-4105
    • Georgitsi, M.1
  • 15
    • 77954314418 scopus 로고    scopus 로고
    • The clinical and genetic characteristics of patients with familial isolated pituitary adenomas. Hormones, 11th International Workshop of MEN meeting, Delphi 7, O8
    • Chahal, H.S. et al. (2008) The clinical and genetic characteristics of patients with familial isolated pituitary adenomas. Hormones, 11th International Workshop of MEN meeting, Delphi 7 (Suppl. 2), O8.
    • (2008) , Issue.SUPPL. 2
    • Chahal, H.S.1
  • 16
    • 77955078517 scopus 로고    scopus 로고
    • Characterization of aryl hydrocarbon receptor interacting protein (AIP) mutations in familial isolated pituitary adenoma families. Hum. Mut., In Press
    • Igreja, S.C. et al. (2010) Characterization of aryl hydrocarbon receptor interacting protein (AIP) mutations in familial isolated pituitary adenoma families. Hum. Mut., In Press.
    • (2010)
    • Igreja, S.C.1
  • 17
    • 77954314217 scopus 로고    scopus 로고
    • Germline AIP, MEN1, PRKAR1A, CDKN1B (p27Kip1) and CDKN2C (p18INK4c) gene mutations in a large cohort of pediatric patients with pituitary adenomas occurring in isolation or with associated syndromic features. Proceedings of the 90th Annual Meeting of the Endocrine Society, OR38-1
    • Beckers, A. et al. (2008) Germline AIP, MEN1, PRKAR1A, CDKN1B (p27Kip1) and CDKN2C (p18INK4c) gene mutations in a large cohort of pediatric patients with pituitary adenomas occurring in isolation or with associated syndromic features. Proceedings of the 90th Annual Meeting of the Endocrine Society, OR38-1.
    • (2008)
    • Beckers, A.1
  • 18
    • 35549003662 scopus 로고    scopus 로고
    • Variable pathological and clinical features of a large Brazilian family harboring a mutation in the aryl hydrocarbon receptor-interacting protein gene
    • Naves L.A., et al. Variable pathological and clinical features of a large Brazilian family harboring a mutation in the aryl hydrocarbon receptor-interacting protein gene. Eur. J. Endocrinol. 2007, 157:383-391.
    • (2007) Eur. J. Endocrinol. , vol.157 , pp. 383-391
    • Naves, L.A.1
  • 19
    • 72749104668 scopus 로고    scopus 로고
    • Genome-wide scan identifies novel modifier loci of acromegalic phenotypes for isolated familial somatotropinoma
    • Khoo S.K., et al. Genome-wide scan identifies novel modifier loci of acromegalic phenotypes for isolated familial somatotropinoma. Endocr. Relat. Cancer 2009, 16:1057-1063.
    • (2009) Endocr. Relat. Cancer , vol.16 , pp. 1057-1063
    • Khoo, S.K.1
  • 20
    • 70449724709 scopus 로고    scopus 로고
    • Aggressive pituitary adenomas occurring in young patients in a large Polynesian kindred with a germline R271W mutation in the AIP gene
    • Jennings J., et al. Aggressive pituitary adenomas occurring in young patients in a large Polynesian kindred with a germline R271W mutation in the AIP gene. Eur. J. Endocrinol. 2009, 161:799-804.
    • (2009) Eur. J. Endocrinol. , vol.161 , pp. 799-804
    • Jennings, J.1
  • 21
    • 53749085204 scopus 로고    scopus 로고
    • Large genomic deletions of aryl hydrocarbon receptor interacting protein (AIP) gene in pituitary adenoma predisposition
    • Georgitsi M., et al. Large genomic deletions of aryl hydrocarbon receptor interacting protein (AIP) gene in pituitary adenoma predisposition. J. Clin. Endocrinol. Metab. 2008, 93:4146-4151.
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 4146-4151
    • Georgitsi, M.1
  • 22
    • 34249844498 scopus 로고    scopus 로고
    • Mutations in the aryl hydrocarbon receptor interacting protein gene are not highly prevalent among subjects with sporadic pituitary adenomas
    • Barlier A., et al. Mutations in the aryl hydrocarbon receptor interacting protein gene are not highly prevalent among subjects with sporadic pituitary adenomas. J. Clin. Endocrinol. Metab. 2007, 92:1952-1955.
    • (2007) J. Clin. Endocrinol. Metab. , vol.92 , pp. 1952-1955
    • Barlier, A.1
  • 23
    • 34547426945 scopus 로고    scopus 로고
    • Germline inactivating mutations of the aryl hydrocarbon receptor-interacting protein gene in a large cohort of sporadic acromegaly: mutations are found in a subset of young patients with macroadenomas
    • Cazabat L., et al. Germline inactivating mutations of the aryl hydrocarbon receptor-interacting protein gene in a large cohort of sporadic acromegaly: mutations are found in a subset of young patients with macroadenomas. Eur. J. Endocrinol. 2007, 157:1-8.
    • (2007) Eur. J. Endocrinol. , vol.157 , pp. 1-8
    • Cazabat, L.1
  • 24
    • 2942731315 scopus 로고    scopus 로고
    • A meiotic recombination in a new isolated familial somatotropinoma kindred
    • Luccio-Camelo D.C., et al. A meiotic recombination in a new isolated familial somatotropinoma kindred. Eur. J. Endocrinol. 2004, 150:643-648.
    • (2004) Eur. J. Endocrinol. , vol.150 , pp. 643-648
    • Luccio-Camelo, D.C.1
  • 25
    • 77954314728 scopus 로고    scopus 로고
    • Familial somatotropinoma and adrenocortical carcinoma due to a novel germline mutation and loss of the wild-type allele of the AIP gene. Proceedings of the 90th Annual Meeting of the Endocrine Society.
    • Toledo, R.A. et al. (2008) Familial somatotropinoma and adrenocortical carcinoma due to a novel germline mutation and loss of the wild-type allele of the AIP gene. Proceedings of the 90th Annual Meeting of the Endocrine Society, P1-488.
    • (2008) , pp. 1-488
    • Toledo, R.A.1
  • 26
    • 0041856176 scopus 로고    scopus 로고
    • Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2
    • Bolger G.B., et al. Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2. J. Biol. Chem. 2003, 278:33351-33363.
    • (2003) J. Biol. Chem. , vol.278 , pp. 33351-33363
    • Bolger, G.B.1
  • 27
    • 57049102370 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor interacting protein gene (AIP) mutations are rare in patients with hormone secreting or non-secreting pituitary adenomas
    • Buchbinder S., et al. Aryl hydrocarbon receptor interacting protein gene (AIP) mutations are rare in patients with hormone secreting or non-secreting pituitary adenomas. Exp. Clin. Endorcrinol. Diabetes 2008, 116:625-628.
    • (2008) Exp. Clin. Endorcrinol. Diabetes , vol.116 , pp. 625-628
    • Buchbinder, S.1
  • 28
    • 77954310443 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor interacting protein gene mutations in bulgarian FIPA and young sporadic pituitary adenoma patients. Proceedings of the 90th Annual Meeting of the Endocrine Society.
    • Yaneva, M. et al. (2008) Aryl hydrocarbon receptor interacting protein gene mutations in bulgarian FIPA and young sporadic pituitary adenoma patients. Proceedings of the 90th Annual Meeting of the Endocrine Society, P3-520.
    • (2008) , pp. 3-520
    • Yaneva, M.1
  • 30
    • 33947218540 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor-interacting protein gene is rarely mutated in sporadic GH-secreting adenomas
    • Iwata T., et al. The aryl hydrocarbon receptor-interacting protein gene is rarely mutated in sporadic GH-secreting adenomas. Clin. Endocrinol. (Oxf.) 2007, 66:499-502.
    • (2007) Clin. Endocrinol. (Oxf.) , vol.66 , pp. 499-502
    • Iwata, T.1
  • 31
    • 77954316232 scopus 로고    scopus 로고
    • Occurrence of AIP mutations in sporadic pituitary adenomas and familial isolated pituitary adenomas kindreds in Valencia, Spain. Proceedings of the 90th Annual Meeting of the Endocrine Society.
    • Montanana, C.F. et al. (2008) Occurrence of AIP mutations in sporadic pituitary adenomas and familial isolated pituitary adenomas kindreds in Valencia, Spain. Proceedings of the 90th Annual Meeting of the Endocrine Society, P3-775.
    • (2008) , pp. 3-775
    • Montanana, C.F.1
  • 32
    • 35948953263 scopus 로고    scopus 로고
    • No evidence of somatic aryl hydrocarbon receptor interacting protein mutations in sporadic endocrine neoplasia
    • Raitila A., et al. No evidence of somatic aryl hydrocarbon receptor interacting protein mutations in sporadic endocrine neoplasia. Endocr. Relat. Cancer 2007, 14:901-906.
    • (2007) Endocr. Relat. Cancer , vol.14 , pp. 901-906
    • Raitila, A.1
  • 33
    • 51649091623 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor interacting protein (AIP) gene mutation analysis in children and adolescents with sporadic pituitary adenomas
    • Georgitsi M., et al. Aryl hydrocarbon receptor interacting protein (AIP) gene mutation analysis in children and adolescents with sporadic pituitary adenomas. Clin. Endocrinol. (Oxf.) 2008, 69:621-627.
    • (2008) Clin. Endocrinol. (Oxf.) , vol.69 , pp. 621-627
    • Georgitsi, M.1
  • 34
    • 77954309242 scopus 로고    scopus 로고
    • The role of AIP gene in Brazilian patients with sporadic and familial acromegaly. Proceedings of the 90th Annual Meeting of the Endocrine Society.
    • Toledo, R.A. et al. (2008) The role of AIP gene in Brazilian patients with sporadic and familial acromegaly. Proceedings of the 90th Annual Meeting of the Endocrine Society, P3-738.
    • (2008) , pp. 3-738
    • Toledo, R.A.1
  • 35
    • 67650251691 scopus 로고    scopus 로고
    • The tyrosine kinase receptor RET interacts in vivo with aryl hydrocarbon receptor-interacting protein to alter survivin availability
    • Vargiolu M., et al. The tyrosine kinase receptor RET interacts in vivo with aryl hydrocarbon receptor-interacting protein to alter survivin availability. J. Clin. Endocrinol. Metab. 2009, 94:2571-2578.
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 2571-2578
    • Vargiolu, M.1
  • 36
    • 37249016342 scopus 로고    scopus 로고
    • Deletion of the aryl hydrocarbon receptor-associated protein 9 leads to cardiac malformation and embryonic lethality
    • Lin B.C., et al. Deletion of the aryl hydrocarbon receptor-associated protein 9 leads to cardiac malformation and embryonic lethality. J. Biol. Chem. 2007, 282:35924-35932.
    • (2007) J. Biol. Chem. , vol.282 , pp. 35924-35932
    • Lin, B.C.1
  • 37
    • 54349087775 scopus 로고    scopus 로고
    • A hypomorphic allele of aryl-hydrocarbon receptor-associated-9 produces a phenocopy of the Ahr null
    • Lin B.C., et al. A hypomorphic allele of aryl-hydrocarbon receptor-associated-9 produces a phenocopy of the Ahr null. Mol. Pharmacol. 2008, 74:1367-1371.
    • (2008) Mol. Pharmacol. , vol.74 , pp. 1367-1371
    • Lin, B.C.1
  • 38
    • 73549093585 scopus 로고    scopus 로고
    • The expression of AIP-related molecules in elucidation of cellular pathways in pituitary adenomas
    • Heliovaara E., et al. The expression of AIP-related molecules in elucidation of cellular pathways in pituitary adenomas. Am. J. Pathol. 2009, 175:2501-2507.
    • (2009) Am. J. Pathol. , vol.175 , pp. 2501-2507
    • Heliovaara, E.1
  • 39
    • 77954316051 scopus 로고    scopus 로고
    • AIP - a tumour suppressor gene in familial pituitary tumours, affects the cell cycle proteins and the caspase cascade. Hormones, 11th International Workshop of MEN meeting, Delphi 7, O9
    • Leontiou, C.A. et al. (2008) AIP - a tumour suppressor gene in familial pituitary tumours, affects the cell cycle proteins and the caspase cascade. Hormones, 11th International Workshop of MEN meeting, Delphi 7 (Suppl. 2), O9.
    • (2008) , Issue.SUPPL. 2
    • Leontiou, C.A.1
  • 40
    • 0038381492 scopus 로고    scopus 로고
    • Resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity and abnormal liver development in mice carrying a mutation in the nuclear localization sequence of the aryl hydrocarbon receptor
    • Bunger M.K., et al. Resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity and abnormal liver development in mice carrying a mutation in the nuclear localization sequence of the aryl hydrocarbon receptor. J. Biol. Chem. 2003, 278:17767-17774.
    • (2003) J. Biol. Chem. , vol.278 , pp. 17767-17774
    • Bunger, M.K.1
  • 41
    • 0141923738 scopus 로고    scopus 로고
    • T cell-specific disruption of arylhydrocarbon receptor nuclear translocator (Arnt) gene causes resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced thymic involution
    • Tomita S., et al. T cell-specific disruption of arylhydrocarbon receptor nuclear translocator (Arnt) gene causes resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced thymic involution. J. Immunol. 2003, 171:4113-4120.
    • (2003) J. Immunol. , vol.171 , pp. 4113-4120
    • Tomita, S.1
  • 42
    • 1942501666 scopus 로고    scopus 로고
    • Patent ductus venosus and dioxin resistance in mice harboring a hypomorphic Arnt allele
    • Walisser J.A., et al. Patent ductus venosus and dioxin resistance in mice harboring a hypomorphic Arnt allele. J. Biol. Chem. 2004, 279:16326-16331.
    • (2004) J. Biol. Chem. , vol.279 , pp. 16326-16331
    • Walisser, J.A.1
  • 43
    • 34447511096 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein
    • Barouki R., et al. The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein. FEBS Lett. 2007, 581:3608-3615.
    • (2007) FEBS Lett. , vol.581 , pp. 3608-3615
    • Barouki, R.1
  • 44
    • 0023742858 scopus 로고
    • Association of the Ah receptor with the 90-kDa heat shock protein
    • Perdew G.H. Association of the Ah receptor with the 90-kDa heat shock protein. J. Biol. Chem. 1988, 263:13802-13805.
    • (1988) J. Biol. Chem. , vol.263 , pp. 13802-13805
    • Perdew, G.H.1
  • 45
    • 0030897705 scopus 로고    scopus 로고
    • Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo
    • Carver L.A., Bradfield C.A. Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo. J. Biol. Chem. 1997, 272:11452-11456.
    • (1997) J. Biol. Chem. , vol.272 , pp. 11452-11456
    • Carver, L.A.1    Bradfield, C.A.2
  • 46
    • 0031002895 scopus 로고    scopus 로고
    • A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Ma Q., Whitlock J.P. A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. J. Biol. Chem. 1997, 272:8878-8884.
    • (1997) J. Biol. Chem. , vol.272 , pp. 8878-8884
    • Ma, Q.1    Whitlock, J.P.2
  • 47
    • 0031882767 scopus 로고    scopus 로고
    • Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity
    • Meyer B.K., et al. Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity. Mol. Cell Biol. 1998, 18:978-988.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 978-988
    • Meyer, B.K.1
  • 48
    • 0033531928 scopus 로고    scopus 로고
    • Evidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (Aryl hydrocarbon) receptor
    • Kazlauskas A., et al. Evidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (Aryl hydrocarbon) receptor. J. Biol. Chem. 1999, 274:13519-13524.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13519-13524
    • Kazlauskas, A.1
  • 49
    • 28544446058 scopus 로고    scopus 로고
    • Mitochondrial tumour suppressors: a genetic and biochemical update
    • Gottlieb E., Tomlinson I.P. Mitochondrial tumour suppressors: a genetic and biochemical update. Nat. Rev. Cancer 2005, 5:857-866.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 857-866
    • Gottlieb, E.1    Tomlinson, I.P.2
  • 50
    • 23944521767 scopus 로고    scopus 로고
    • The transactivation domain of the Ah receptor is a key determinant of cellular localization and ligand-independent nucleocytoplasmic shuttling properties
    • Ramadoss P., Perdew G.H. The transactivation domain of the Ah receptor is a key determinant of cellular localization and ligand-independent nucleocytoplasmic shuttling properties. Biochemistry 2005, 44:11148-11159.
    • (2005) Biochemistry , vol.44 , pp. 11148-11159
    • Ramadoss, P.1    Perdew, G.H.2
  • 51
    • 0142027923 scopus 로고    scopus 로고
    • AIP is a mitochondrial import mediator that binds to both import receptor Tom20 and preproteins
    • Yano M., et al. AIP is a mitochondrial import mediator that binds to both import receptor Tom20 and preproteins. J. Cell Biol. 2003, 163:45-56.
    • (2003) J. Cell Biol. , vol.163 , pp. 45-56
    • Yano, M.1
  • 52
    • 34047094888 scopus 로고    scopus 로고
    • Dioxin receptor is a ligand-dependent E3 ubiquitin ligase
    • Ohtake F., et al. Dioxin receptor is a ligand-dependent E3 ubiquitin ligase. Nature 2007, 446:562-566.
    • (2007) Nature , vol.446 , pp. 562-566
    • Ohtake, F.1
  • 53
    • 0034928843 scopus 로고    scopus 로고
    • Aromatic hydrocarbon receptor-driven Bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals
    • Matikainen T., et al. Aromatic hydrocarbon receptor-driven Bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals. Nat. Genet. 2001, 28:355-360.
    • (2001) Nat. Genet. , vol.28 , pp. 355-360
    • Matikainen, T.1
  • 54
    • 0024591780 scopus 로고
    • Reduced fecundability in women with prenatal exposure to cigarette smoking
    • Weinberg C.R., et al. Reduced fecundability in women with prenatal exposure to cigarette smoking. Am. J. Epidemiol. 1989, 129:1072-1078.
    • (1989) Am. J. Epidemiol. , vol.129 , pp. 1072-1078
    • Weinberg, C.R.1
  • 55
    • 36849082675 scopus 로고    scopus 로고
    • Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of Harakiri
    • Jurisicova A., et al. Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of Harakiri. J. Clin. Invest. 2007, 117:3971-3978.
    • (2007) J. Clin. Invest. , vol.117 , pp. 3971-3978
    • Jurisicova, A.1
  • 56
    • 0032535055 scopus 로고    scopus 로고
    • Resveratrol inhibits transcription of CYP1A1 in vitro by preventing activation of the aryl hydrocarbon receptor
    • Ciolino H.P., et al. Resveratrol inhibits transcription of CYP1A1 in vitro by preventing activation of the aryl hydrocarbon receptor. Cancer Res. 1998, 58:5707-5712.
    • (1998) Cancer Res. , vol.58 , pp. 5707-5712
    • Ciolino, H.P.1
  • 57
    • 41649093550 scopus 로고    scopus 로고
    • TCDD deregulates contact inhibition in rat liver oval cells via Ah receptor, JunD and cyclin A
    • Weiss C., et al. TCDD deregulates contact inhibition in rat liver oval cells via Ah receptor, JunD and cyclin A. Oncogene 2008, 27:2198-2207.
    • (2008) Oncogene , vol.27 , pp. 2198-2207
    • Weiss, C.1
  • 58
    • 27944458757 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor, cell cycle regulation, toxicity, and tumorigenesis
    • Marlowe J.L., Puga A. Aryl hydrocarbon receptor, cell cycle regulation, toxicity, and tumorigenesis. J. Cell Biochem. 2005, 96:1174-1184.
    • (2005) J. Cell Biochem. , vol.96 , pp. 1174-1184
    • Marlowe, J.L.1    Puga, A.2
  • 59
    • 23344452961 scopus 로고    scopus 로고
    • Immortalized mouse mammary fibroblasts lacking dioxin receptor have impaired tumorigenicity in a subcutaneous mouse xenograft model
    • Mulero-Navarro S., et al. Immortalized mouse mammary fibroblasts lacking dioxin receptor have impaired tumorigenicity in a subcutaneous mouse xenograft model. J. Biol. Chem. 2005, 280:28731-28741.
    • (2005) J. Biol. Chem. , vol.280 , pp. 28731-28741
    • Mulero-Navarro, S.1
  • 60
    • 0029963257 scopus 로고    scopus 로고
    • The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin
    • Ma Q., Whitlock J.P. The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin. Mol. Cell Biol. 1996, 16:2144-2150.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 2144-2150
    • Ma, Q.1    Whitlock, J.P.2
  • 61
    • 0031745543 scopus 로고    scopus 로고
    • Aryl-hydrocarbon receptor is an inhibitory regulator of lipid synthesis and of commitment to adipogenesis
    • Alexander D.L., et al. Aryl-hydrocarbon receptor is an inhibitory regulator of lipid synthesis and of commitment to adipogenesis. J. Cell Sci. 1998, 111:3311-3322.
    • (1998) J. Cell Sci. , vol.111 , pp. 3311-3322
    • Alexander, D.L.1
  • 62
    • 0034099303 scopus 로고    scopus 로고
    • 2/M phases in aryl hydrocarbon receptor-null embryo fibroblast
    • 2/M phases in aryl hydrocarbon receptor-null embryo fibroblast. Mol. Pharmacol. 2000, 57:1056-1063.
    • (2000) Mol. Pharmacol. , vol.57 , pp. 1056-1063
    • Elizondo, G.1
  • 63
    • 1842857594 scopus 로고    scopus 로고
    • Overexpression of the aryl hydrocarbon receptor (AhR) accelerates the cell proliferation of A549 cells
    • Shimba S., et al. Overexpression of the aryl hydrocarbon receptor (AhR) accelerates the cell proliferation of A549 cells. J. Biochem. (Tokyo) 2002, 132:795-802.
    • (2002) J. Biochem. (Tokyo) , vol.132 , pp. 795-802
    • Shimba, S.1
  • 64
    • 3142689710 scopus 로고    scopus 로고
    • A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice
    • Moennikes O., et al. A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice. Cancer Res. 2004, 64:4707-4710.
    • (2004) Cancer Res. , vol.64 , pp. 4707-4710
    • Moennikes, O.1
  • 65
    • 12344289296 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-activating polychlorinated biphenyls and their hydroxylated metabolites induce cell proliferation in contact-inhibited rat liver epithelial cells
    • Vondracek J., et al. Aryl hydrocarbon receptor-activating polychlorinated biphenyls and their hydroxylated metabolites induce cell proliferation in contact-inhibited rat liver epithelial cells. Toxicol. Sci. 2005, 83:53-63.
    • (2005) Toxicol. Sci. , vol.83 , pp. 53-63
    • Vondracek, J.1
  • 66
    • 54249157595 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor binds to E2F1 and inhibits E2F1-induced apoptosis
    • Marlowe J.L., et al. The aryl hydrocarbon receptor binds to E2F1 and inhibits E2F1-induced apoptosis. Mol. Biol. Cell 2008, 19:3263-3271.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 3263-3271
    • Marlowe, J.L.1
  • 67
    • 0032575589 scopus 로고    scopus 로고
    • A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle
    • Ge N.L., Elferink C.J. A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle. J. Biol. Chem. 1998, 273:22708-22713.
    • (1998) J. Biol. Chem. , vol.273 , pp. 22708-22713
    • Ge, N.L.1    Elferink, C.J.2
  • 68
    • 11244353490 scopus 로고    scopus 로고
    • Multiple mechanisms are involved in Ah receptor-mediated cell cycle arrest
    • Huang G., Elferink C.J. Multiple mechanisms are involved in Ah receptor-mediated cell cycle arrest. Mol. Pharmacol. 2005, 67:88-96.
    • (2005) Mol. Pharmacol. , vol.67 , pp. 88-96
    • Huang, G.1    Elferink, C.J.2
  • 69
    • 39149091424 scopus 로고    scopus 로고
    • Molecular mechanisms of p21 and p27 induction by 3-methylcholanthrene, an aryl-hydrocarbon receptor agonist, involved in antiproliferation of human umbilical vascular endothelial cells
    • Pang P.H., et al. Molecular mechanisms of p21 and p27 induction by 3-methylcholanthrene, an aryl-hydrocarbon receptor agonist, involved in antiproliferation of human umbilical vascular endothelial cells. J. Cell. Physiol. 2008, 215:161-171.
    • (2008) J. Cell. Physiol. , vol.215 , pp. 161-171
    • Pang, P.H.1
  • 70
    • 70449950609 scopus 로고    scopus 로고
    • Expression of aryl hydrocarbon receptor (AHR) and AHR-interacting protein in pituitary adenomas: pathological and clinical implications
    • Jaffrain-Rea M.L., et al. Expression of aryl hydrocarbon receptor (AHR) and AHR-interacting protein in pituitary adenomas: pathological and clinical implications. Endocr. Relat. Cancer 2009, 16:1029-1043.
    • (2009) Endocr. Relat. Cancer , vol.16 , pp. 1029-1043
    • Jaffrain-Rea, M.L.1
  • 71
    • 0029017174 scopus 로고
    • The cyclic adenosine 3ó,5ó-monophosphate-responsive factor CREB is constitutively activated in human somatotroph adenomas
    • Bertherat J., et al. The cyclic adenosine 3ó,5ó-monophosphate-responsive factor CREB is constitutively activated in human somatotroph adenomas. Mol. Endocrinol. 1995, 9:777-783.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 777-783
    • Bertherat, J.1
  • 72
    • 21544468008 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor activation by cAMP vs. dioxin: divergent signaling pathways
    • Oesch-Bartlomowicz B., et al. Aryl hydrocarbon receptor activation by cAMP vs. dioxin: divergent signaling pathways. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:9218-9223.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 9218-9223
    • Oesch-Bartlomowicz, B.1
  • 73
    • 34250346920 scopus 로고    scopus 로고
    • Phosphodiesterase 2A forms a complex with the co-chaperone XAP2 and regulates nuclear translocation of the aryl hydrocarbon receptor
    • de Oliveira S.K., et al. Phosphodiesterase 2A forms a complex with the co-chaperone XAP2 and regulates nuclear translocation of the aryl hydrocarbon receptor. J. Biol. Chem. 2007, 282:13656-13663.
    • (2007) J. Biol. Chem. , vol.282 , pp. 13656-13663
    • de Oliveira, S.K.1
  • 74
    • 33745548423 scopus 로고    scopus 로고
    • A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia
    • Horvath A., et al. A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia. Nat. Genet. 2006, 38:794-800.
    • (2006) Nat. Genet. , vol.38 , pp. 794-800
    • Horvath, A.1
  • 75
    • 39049101528 scopus 로고    scopus 로고
    • Mutation in PDE8B, a cyclic AMP-specific phosphodiesterase in adrenal hyperplasia
    • Horvath A., et al. Mutation in PDE8B, a cyclic AMP-specific phosphodiesterase in adrenal hyperplasia. N. Eng. J. Med. 2008, 358:750-752.
    • (2008) N. Eng. J. Med. , vol.358 , pp. 750-752
    • Horvath, A.1
  • 76
    • 53249142160 scopus 로고    scopus 로고
    • A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex
    • Horvath A., et al. A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex. Eur. J. Hum. Genet. 2008, 16:1245-1253.
    • (2008) Eur. J. Hum. Genet. , vol.16 , pp. 1245-1253
    • Horvath, A.1
  • 77
    • 36949024511 scopus 로고    scopus 로고
    • The PPAR alpha-humanized mouse: a model to investigate species differences in liver toxicity mediated by PPAR alpha
    • Yang Q., et al. The PPAR alpha-humanized mouse: a model to investigate species differences in liver toxicity mediated by PPAR alpha. Toxicol. Sci. 2008, 101:132-139.
    • (2008) Toxicol. Sci. , vol.101 , pp. 132-139
    • Yang, Q.1
  • 78
    • 0037799205 scopus 로고    scopus 로고
    • Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2
    • Sumanasekera W.K., et al. Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2. J. Biol. Chem. 2003, 278:4467-4473.
    • (2003) J. Biol. Chem. , vol.278 , pp. 4467-4473
    • Sumanasekera, W.K.1
  • 79
    • 0032509519 scopus 로고    scopus 로고
    • Characterization of the Ah receptor-associated protein, ARA9
    • Carver L.A., et al. Characterization of the Ah receptor-associated protein, ARA9. J Biol. Chem 1998, 273:33580-33587.
    • (1998) J Biol. Chem , vol.273 , pp. 33580-33587
    • Carver, L.A.1
  • 80
    • 67349167633 scopus 로고    scopus 로고
    • XAP2 inhibits glucocorticoid receptor activity in mammalian cells
    • Laenger A., et al. XAP2 inhibits glucocorticoid receptor activity in mammalian cells. FEBS Lett. 2009, 583:1493-1498.
    • (2009) FEBS Lett. , vol.583 , pp. 1493-1498
    • Laenger, A.1
  • 81
    • 33749235730 scopus 로고    scopus 로고
    • The co-chaperone XAP2 is required for activation of hypothalamic thyrotropin-releasing hormone transcription in vivo
    • Froidevaux M.S., et al. The co-chaperone XAP2 is required for activation of hypothalamic thyrotropin-releasing hormone transcription in vivo. EMBO Rep. 2006, 7:1035-1039.
    • (2006) EMBO Rep. , vol.7 , pp. 1035-1039
    • Froidevaux, M.S.1
  • 82
    • 48749106559 scopus 로고    scopus 로고
    • Neonatal thyroid function in Seveso 25 years after maternal exposure to dioxin
    • Baccarelli A., et al. Neonatal thyroid function in Seveso 25 years after maternal exposure to dioxin. PLoS. Med. 2008, 5:e161.
    • (2008) PLoS. Med. , vol.5
    • Baccarelli, A.1
  • 83
    • 58149359291 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor interacting protein and pituitary adenomas: a population-based study on subjects exposed to dioxin after the Seveso, Italy, accident
    • Pesatori A., et al. Aryl hydrocarbon receptor interacting protein and pituitary adenomas: a population-based study on subjects exposed to dioxin after the Seveso, Italy, accident. Eur. J. Endocrinol. 2008, 159:699-703.
    • (2008) Eur. J. Endocrinol. , vol.159 , pp. 699-703
    • Pesatori, A.1
  • 84
    • 1442283728 scopus 로고    scopus 로고
    • The EBNA-3 gene family proteins disrupt the G2/M checkpoint
    • Krauer K.G., et al. The EBNA-3 gene family proteins disrupt the G2/M checkpoint. Oncogene 2004, 23:1342-1353.
    • (2004) Oncogene , vol.23 , pp. 1342-1353
    • Krauer, K.G.1
  • 85
    • 0034732259 scopus 로고    scopus 로고
    • Epstein-Barr virus encodes nuclear protein EBNA-3 binds XAP-2, a protein associated with hepatitis B virus X antigen
    • Kashuba E., et al. Epstein-Barr virus encodes nuclear protein EBNA-3 binds XAP-2, a protein associated with hepatitis B virus X antigen. Oncogene 2000, 19:1801-1806.
    • (2000) Oncogene , vol.19 , pp. 1801-1806
    • Kashuba, E.1
  • 86
    • 54349127541 scopus 로고    scopus 로고
    • 13-mediated signalling in mammalian physiology and disease
    • 13-mediated signalling in mammalian physiology and disease. Trends Pharmacol. Sci. 2008, 29:582-589.
    • (2008) Trends Pharmacol. Sci. , vol.29 , pp. 582-589
    • Worzfeld, T.1
  • 87
    • 0037031156 scopus 로고    scopus 로고
    • 13 interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity
    • 13 interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity. Curr. Biol. 2002, 12:1353-1358.
    • (2002) Curr. Biol. , vol.12 , pp. 1353-1358
    • Yamaguchi, Y.1
  • 88
    • 67349103874 scopus 로고    scopus 로고
    • G-protein signalling negatively regulates the stability of aryl hydrocarbon receptor
    • Nakata A., et al. G-protein signalling negatively regulates the stability of aryl hydrocarbon receptor. EMBO Rep. 2009, 10:622-628.
    • (2009) EMBO Rep. , vol.10 , pp. 622-628
    • Nakata, A.1
  • 89
    • 33747677470 scopus 로고    scopus 로고
    • Regulation of survivin stability by the aryl hydrocarbon receptor-interacting protein
    • Kang B.H., Altieri D.C. Regulation of survivin stability by the aryl hydrocarbon receptor-interacting protein. J. Biol. Chem. 2006, 281:24721-24727.
    • (2006) J. Biol. Chem. , vol.281 , pp. 24721-24727
    • Kang, B.H.1    Altieri, D.C.2
  • 90
    • 34247192417 scopus 로고    scopus 로고
    • The dependence receptor Ret induces apoptosis in somatotrophs through a Pit-1/p53 pathway, preventing tumor growth
    • Canibano C., et al. The dependence receptor Ret induces apoptosis in somatotrophs through a Pit-1/p53 pathway, preventing tumor growth. EMBO J. 2007, 26:2015-2028.
    • (2007) EMBO J. , vol.26 , pp. 2015-2028
    • Canibano, C.1
  • 91
    • 0034731609 scopus 로고    scopus 로고
    • The immunophilin-like protein XAP2 regulates ubiquitination and subcellular localization of the dioxin receptor
    • Kazlauskas A., et al. The immunophilin-like protein XAP2 regulates ubiquitination and subcellular localization of the dioxin receptor. J. Biol. Chem. 2000, 275:41317-41324.
    • (2000) J. Biol. Chem. , vol.275 , pp. 41317-41324
    • Kazlauskas, A.1
  • 92
    • 0034732259 scopus 로고    scopus 로고
    • Epstein-Barr virus encoded nuclear protein EBNA-3 binds XAP-2, a protein associated with hepatitis B virus X antigen
    • Kashuba E., et al. Epstein-Barr virus encoded nuclear protein EBNA-3 binds XAP-2, a protein associated with hepatitis B virus X antigen. Oncogene 2000, 19:1801-1806.
    • (2000) Oncogene , vol.19 , pp. 1801-1806
    • Kashuba, E.1


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