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Volumn , Issue 20, 2010, Pages 3823-3830

Alkoxy-5-nitrosopyrimidines: Useful building block for the generation of biologically active compounds

Author keywords

Animation; Antiviral agents; Nitrogen heterocycles; Nitrosation; Nucleophilic substitution

Indexed keywords


EID: 77954306756     PISSN: 1434193X     EISSN: 10990690     Source Type: Journal    
DOI: 10.1002/ejoc.201000195     Document Type: Article
Times cited : (23)

References (69)
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    • (1984) Comprehensive Heterocyclic Chemistry , vol.3
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  • 5
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    • and references cited, therein
    • a) H. Vorbrüggen, Adv. Heterocyci Chem. 1990, 49, 117-192, and references cited, therein;
    • (1990) Adv. Heterocyci Chem. , vol.49 , pp. 117-192
    • Vorbrüggen, H.1
  • 9
    • 32444446491 scopus 로고    scopus 로고
    • and references cited, therein
    • b) C. Wéber, A. Demeter, I. Greiner, Tetrahedron 2006, 62, 2304-2312, and references cited, therein;
    • (2006) Tetrahedron , vol.62 , pp. 2304-2312
    • Wéber, C.1    Demeter, A.2    Greiner, I.3
  • 34
    • 77954249934 scopus 로고    scopus 로고
    • In this sense, the activating effect of the nitro group on the aminolysis has been most studied and, therefore, most synthetically employed. Nevertheless, from a synthetic point of view, it must be taken into account that the nitro group is remarkably resistant to reduction compared to the nitroso group. For recent illustrative examples, see: a) O. B. Riabova, V. A. Makarov, V. G. Granik, C. Párkányi, J. Heterocycl Chem. 2008, 45, 621643;
    • (2008) J. Heterocycl Chem. , vol.45 , pp. 621643
    • Riabova, O.B.1    Makarov, V.A.2    Granik, V.G.3    Párkányi, C.4
  • 38
    • 0343341825 scopus 로고
    • Ed.: H. Feuer, Wiley-Interscience, New York
    • As a rule, amines attack nitrosobenzenes at the N-atom of the nitroso group, however, in these reactions, the nitroso group remained intact, see: J. H. Boyer, in: The Chemistry of the Nitro and Nitroso Groups (Ed.: H. Feuer), Wiley-Interscience, New York, 1970, vol. 12, pp. 278-280.
    • (1970) The Chemistry of the Nitro and Nitroso Groups , vol.12 , pp. 278-280
    • Boyer, J.H.1
  • 58
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    • Interesting theoretical investigations focused, on restricted. Cnitroso rotation can be found in: a) G. Urbelis, I. Susvilo, S. Tumkevicius, J. Mol. Model. 2007, 13, 219-224;
    • (2007) J. Mol. Model. , vol.13 , pp. 219-224
    • Urbelis, G.1    Susvilo, I.2    Tumkevicius, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.