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Volumn 56, Issue 1, 2010, Pages 60-67

Hepatoprotective effects of flavonoids from shekwasha (Citrus depressa) against D-galactosamine-induced liver injury in rats

Author keywords

Citrus depressa; D galactosamine; Flavonoids; Liver injury; Shekwasha

Indexed keywords

CARBON TETRACHLORIDE; CITRUS DEPRESSA EXTRACT; DNA; FLAVONOID; GALACTOSAMINE; HEXAMETHOXYFLAVANONE; HEXANE; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NOBILETIN; PARACETAMOL; SILICA GEL; TANGERETIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 77954259834     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.56.60     Document Type: Article
Times cited : (64)

References (54)
  • 1
    • 0029950292 scopus 로고    scopus 로고
    • Fruits and vegetables: Protective or just fellow travelers?
    • Nestle M. 1996. Fruits and vegetables: protective or just fellow travelers? Nutr Rev 54: 255-257.
    • (1996) Nutr Rev , vol.54 , pp. 255-257
    • Nestle, M.1
  • 3
    • 0035013950 scopus 로고    scopus 로고
    • Green tea suppresses lipopolysaccharide-induced liver injury in D-galactosamine-sensitized rats
    • He P, Noda Y, Sugiyama K. 2001. Green tea suppresses lipopolysaccharide-induced liver injury in D-galactosamine-sensitized rats. J Nutr 131: 1560-1567.
    • (2001) J Nutr , vol.131 , pp. 1560-1567
    • He, P.1    Noda, Y.2    Sugiyama, K.3
  • 4
    • 67650727123 scopus 로고    scopus 로고
    • Hepatic cystathionine ß-synthase activity does not increase in response to methionine supplementation in rats fed a low casein diet: Association with plasma homocysteine concentrations
    • Ohuchi S, Morita T, Mori M, Sugiyama K. 2009. Hepatic cystathionine ß-synthase activity does not increase in response to methionine supplementation in rats fed a low casein diet: association with plasma homocysteine concentrations. J Nutr Sci Vitaminol 55: 178-185.
    • (2009) J Nutr Sci Vitaminol , vol.55 , pp. 178-185
    • Ohuchi, S.1    Morita, T.2    Mori, M.3    Sugiyama, K.4
  • 5
    • 0002855103 scopus 로고
    • Chemical investigation of Citrus mitis Blanko-III: Isolation of two new flavanones
    • Sastry GP, Row LR. 1961. Chemical investigation of Citrus mitis Blanko-III: isolation of two new flavanones. Tetrahedron 15: 111-114.
    • (1961) Tetrahedron , vol.15 , pp. 111-114
    • Sastry, G.P.1    Row, L.R.2
  • 6
    • 34548196851 scopus 로고
    • Chemical investigation of Citrus reticulata Blanko
    • Chaliha BP, Sastry GP, Rao PR. 1967. Chemical investigation of Citrus reticulata Blanko. Indian J Chem 5: 239-240.
    • (1967) Indian J Chem , vol.5 , pp. 239-240
    • Chaliha, B.P.1    Sastry, G.P.2    Rao, P.R.3
  • 8
    • 34147148084 scopus 로고    scopus 로고
    • Identification of polymethoxylated flavones from green tangerine peel (Pericarpium Citri Reticulate Viride) by chromatographic and spectroscopic techniques
    • Wang D, Wang J, Huang X, Tu Y, Ni K. 2007. Identification of polymethoxylated flavones from green tangerine peel (Pericarpium Citri Reticulate Viride) by chromatographic and spectroscopic techniques. J Pharm Biomed Anal 44: 63-69.
    • (2007) J Pharm Biomed Anal , vol.44 , pp. 63-69
    • Wang, D.1    Wang, J.2    Huang, X.3    Tu, Y.4    Ni, K.5
  • 9
    • 31344482077 scopus 로고    scopus 로고
    • Nobiletin: Efficient and large quantity isolation from orange peel extract
    • Li S, Yu H, Ho CT. 2006. Nobiletin: efficient and large quantity isolation from orange peel extract. Biomed Chromatogr 20: 133-138.
    • (2006) Biomed Chromatogr , vol.20 , pp. 133-138
    • Li, S.1    Yu, H.2    Ho, C.T.3
  • 11
    • 33846480572 scopus 로고    scopus 로고
    • Determination of polymethoxylated flavones in peels of selected Jamaican and Mexican citrus (Citrus spp.) cultivars by high-performance liquid chromatography
    • Green CO, Wheatley AO, Osagie AU, St A Morrison EY, Asemota HN. 2007. Determination of polymethoxylated flavones in peels of selected Jamaican and Mexican citrus (Citrus spp.) cultivars by high-performance liquid chromatography. Biomed Chromatogr 21: 48-54.
    • (2007) Biomed Chromatogr , vol.21 , pp. 48-54
    • Green, C.O.1    Wheatley, A.O.2    Osagie, A.U.3    St Morrison, E.Y.4    Asemota, H.N.5
  • 14
    • 0036173982 scopus 로고    scopus 로고
    • Inhibition of activator-1 binding activity and phosphatidylinositol 3-kinase pathway by nobiletin, a polymethoxy flavonoid, results in augmentation of tissue inhibitor of metalloproteinase-1 production and suppression of protection of matrix metalloproteinase-1 and -9 in human fibrosarcoma HT-1080 cells
    • Sato T, Koike L, Miyata Y, Hirata M, Mimaki Y, Sashida Y, Yano M, Ito A. 2002. Inhibition of activator-1 binding activity and phosphatidylinositol 3-kinase pathway by nobiletin, a polymethoxy flavonoid, results in augmentation of tissue inhibitor of metalloproteinase-1 production and suppression of protection of matrix metalloproteinase-1 and -9 in human fibrosarcoma HT-1080 cells. Cancer Res 62: 1025-1029.
    • (2002) Cancer Res , vol.62 , pp. 1025-1029
    • Sato, T.1    Koike, L.2    Miyata, Y.3    Hirata, M.4    Mimaki, Y.5    Sashida, Y.6    Yano, M.7    Ito, A.8
  • 15
    • 34247137191 scopus 로고    scopus 로고
    • Tangeretin and nobiletin induce G1 cycle arrest but not apoptosis in human breast and colon cancer cells
    • Morley K, Ferguson PJ, Koropatnick J. 2007. Tangeretin and nobiletin induce G1 cycle arrest but not apoptosis in human breast and colon cancer cells. Cancer Lett 251: 168-178.
    • (2007) Cancer Lett , vol.251 , pp. 168-178
    • Morley, K.1    Ferguson, P.J.2    Koropatnick, J.3
  • 16
    • 34147146571 scopus 로고    scopus 로고
    • Protective effects of citrus nobiletin and auraptene in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cells
    • Tang M, Ogawa K, Asamoto M, Hokaiwado N, Seeni A, Suzuki S, Takahashi S, Tanaka T, Ichikawa K, Shirai T. 2007. Protective effects of citrus nobiletin and auraptene in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cells. Cancer Sci 98: 471-477.
    • (2007) Cancer Sci , vol.98 , pp. 471-477
    • Tang, M.1    Ogawa, K.2    Asamoto, M.3    Hokaiwado, N.4    Seeni, A.5    Suzuki, S.6    Takahashi, S.7    Tanaka, T.8    Ichikawa, K.9    Shirai, T.10
  • 17
    • 37349052385 scopus 로고    scopus 로고
    • A citrus polymethoxyflavonoid, nobiletin, is a novel MEK inhibitor that exhibits antitumor metastasis in human fibrosarcoma HT-1080 cells
    • Miyata Y, Sato T, Imada K, Dobashi A, Yano M, Ito A. 2008. A citrus polymethoxyflavonoid, nobiletin, is a novel MEK inhibitor that exhibits antitumor metastasis in human fibrosarcoma HT-1080 cells. Biochem Biophys Res Commun 366: 168-173.
    • (2008) Biochem Biophys Res Commun , vol.366 , pp. 168-173
    • Miyata, Y.1    Sato, T.2    Imada, K.3    Dobashi, A.4    Yano, M.5    Ito, A.6
  • 18
    • 47249110701 scopus 로고    scopus 로고
    • Suppressive effects of nobiletin on hyperleptinemia and colitis-related colon carcinogenesis in male ICR mice
    • Miyamoto S, Yasui Y, Tanaka T, Ohigashi H, Murakami A. 2008. Suppressive effects of nobiletin on hyperleptinemia and colitis-related colon carcinogenesis in male ICR mice. Carcinogenesis 29: 1057-1063.
    • (2008) Carcinogenesis , vol.29 , pp. 1057-1063
    • Miyamoto, S.1    Yasui, Y.2    Tanaka, T.3    Ohigashi, H.4    Murakami, A.5
  • 19
    • 40949149451 scopus 로고    scopus 로고
    • Interactive effects of polymethoxy flavones from citrus on cell growth inhibition in human neuroblastoma SH-SY5Y cells
    • Akao Y, Itoh T, Ohguchi K, Iinuma M, Nozawa Y. 2008. Interactive effects of polymethoxy flavones from citrus on cell growth inhibition in human neuroblastoma SH-SY5Y cells. Bioorg Med Chem Lett 16: 2803-2810.
    • (2008) Bioorg Med Chem Lett , vol.16 , pp. 2803-2810
    • Akao, Y.1    Itoh, T.2    Ohguchi, K.3    Iinuma, M.4    Nozawa, Y.5
  • 20
    • 56149116774 scopus 로고    scopus 로고
    • Apoptic effect of citrus fruit extract nobiletin on lung cancer cell line A549 in vitro and in vivo
    • Luo G, Guan X, Zhou L. 2008. Apoptic effect of citrus fruit extract nobiletin on lung cancer cell line A549 in vitro and in vivo. Cancer Biol Ther 7: 966-973.
    • (2008) Cancer Biol Ther , vol.7 , pp. 966-973
    • Luo, G.1    Guan, X.2    Zhou, L.3
  • 21
    • 0038054004 scopus 로고    scopus 로고
    • Novel anti-inflammatory actions of nobiletin, a citrus polymethoxy flavonoid, on human synovial fibloblasts and mouse macrophages
    • Lin N, Sato T, Takayama Y, Mimaki Y, Sashida Y, Yano M, Ito A. 2003. Novel anti-inflammatory actions of nobiletin, a citrus polymethoxy flavonoid, on human synovial fibloblasts and mouse macrophages. Biochem Pharmacol 65: 2065-2071.
    • (2003) Biochem Pharmacol , vol.65 , pp. 2065-2071
    • Lin, N.1    Sato, T.2    Takayama, Y.3    Mimaki, Y.4    Sashida, Y.5    Yano, M.6    Ito, A.7
  • 22
    • 3042785880 scopus 로고    scopus 로고
    • Prevention of UVB-induced photoinflammation and photoaging by a polymethoxy flavonoid, nobiletin, in human keratinocytes in vivo and in vitro
    • Tanaka S, Sato T, Akimoto N, Yano M, Ito A. 2004. Prevention of UVB-induced photoinflammation and photoaging by a polymethoxy flavonoid, nobiletin, in human keratinocytes in vivo and in vitro. Biochem Pharmacol 68: 433-439.
    • (2004) Biochem Pharmacol , vol.68 , pp. 433-439
    • Tanaka, S.1    Sato, T.2    Akimoto, N.3    Yano, M.4    Ito, A.5
  • 23
    • 31544431713 scopus 로고    scopus 로고
    • Zingiberaceous and citrus constituents, 1'-acetoxychavicol acetate, zerumbone, auraptene, and nobiletin, suppress lipopolysaccharide-induced cyclooxygenase-2 expression in RAW264.7 murine macrophages through different modes of action
    • Murakami A, Shigemori T, Ohigashi H. 2005. Zingiberaceous and citrus constituents, 1'-acetoxychavicol acetate, zerumbone, auraptene, and nobiletin, suppress lipopolysaccharide-induced cyclooxygenase-2 expression in RAW264.7 murine macrophages through different modes of action. J Nutr 135: 2987S-2992S.
    • (2005) J Nutr , vol.135
    • Murakami, A.1    Shigemori, T.2    Ohigashi, H.3
  • 24
    • 34447503642 scopus 로고    scopus 로고
    • Nobiletin from citrus fruit peel inhibits the DNA-binding activity of NF-?B and ROS production in LPS-activated RAW264.7 cells
    • Choi S, Hwang J, Ko H, Park J, Kim S. 2007. Nobiletin from citrus fruit peel inhibits the DNA-binding activity of NF-?B and ROS production in LPS-activated RAW264.7 cells. J Ethnopharmacol 113: 149-155.
    • (2007) J Ethnopharmacol , vol.113 , pp. 149-155
    • Choi, S.1    Hwang, J.2    Ko, H.3    Park, J.4    Kim, S.5
  • 25
    • 34147139570 scopus 로고    scopus 로고
    • Correlation between flavonoid content and the NO production inhibitory activity of peel extracts from various citrus fruits
    • Choi S, Ko H, Ko S, Hwang J, Park J, Kang S, Hsan S, Yun S, Kim S. 2007. Correlation between flavonoid content and the NO production inhibitory activity of peel extracts from various citrus fruits. Bull Pharm Bull 30: 772-778.
    • (2007) Bull Pharm Bull , vol.30 , pp. 772-778
    • Choi, S.1    Ko, H.2    Ko, S.3    Hwang, J.4    Park, J.5    Kang, S.6    Hsan, S.7    Yun, S.8    Kim, S.9
  • 26
    • 34547866464 scopus 로고    scopus 로고
    • Anti-inflammatory property of the urinary metabolites of nobiletin in mouse
    • Li S, Sang S, Pan M, Lai C, Lo C, Yang C, Ho C. 2007. Anti-inflammatory property of the urinary metabolites of nobiletin in mouse. Bioorg Med Chem Lett 17: 5177-5181.
    • (2007) Bioorg Med Chem Lett , vol.17 , pp. 5177-5181
    • Li, S.1    Sang, S.2    Pan, M.3    Lai, C.4    Lo, C.5    Yang, C.6    Ho, C.7
  • 27
    • 34247101939 scopus 로고    scopus 로고
    • Nobiletin enhances differentiation and lipolysis of 3T3-L1 adipocytes
    • Saito T, Abe D, Sekiya K. 2007. Nobiletin enhances differentiation and lipolysis of 3T3-L1 adipocytes. Biochem Biophys Res Commun 357: 371-376.
    • (2007) Biochem Biophys Res Commun , vol.357 , pp. 371-376
    • Saito, T.1    Abe, D.2    Sekiya, K.3
  • 28
    • 46249083291 scopus 로고    scopus 로고
    • Nobiletin, a citrus polymethoxy flavonoid, suppresses gene expression and production of aggrecanases-1 and -2 in collagen-induced arthritic mice
    • Imada K, Lin N, Liu C, Lu A, Chen W, Yano M, Sato T, Ito A. 2008. Nobiletin, a citrus polymethoxy flavonoid, suppresses gene expression and production of aggrecanases-1 and -2 in collagen-induced arthritic mice. Biochem Biophys Res Commun 373: 181-185.
    • (2008) Biochem Biophys Res Commun , vol.373 , pp. 181-185
    • Imada, K.1    Lin, N.2    Liu, C.3    Lu, A.4    Chen, W.5    Yano, M.6    Sato, T.7    Ito, A.8
  • 29
    • 34247246338 scopus 로고    scopus 로고
    • Nobiletin, a citrus flavonoid, reverses learning impairment associated with N-methyl-D-aspartate receptor antagonism by activation of extracellular signal-regulated kinase signaling
    • Nakajima A, Yamakuni T, Matsuzaki K, Nakata N, Onozuka H, Yokosuka A, Sashida Y, Mimaki Y, Ohizumi Y. 2007. Nobiletin, a citrus flavonoid, reverses learning impairment associated with N-methyl-D-aspartate receptor antagonism by activation of extracellular signal-regulated kinase signaling. J Pharmacol Exp Ther 321: 784-790.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 784-790
    • Nakajima, A.1    Yamakuni, T.2    Matsuzaki, K.3    Nakata, N.4    Onozuka, H.5    Yokosuka, A.6    Sashida, Y.7    Mimaki, Y.8    Ohizumi, Y.9
  • 32
    • 0033014916 scopus 로고    scopus 로고
    • Teas and other beverages suppress D-galactosamine-induced liver injury in rats
    • Sugiyama K, He P, Wada S, Saeki S. 1999. Teas and other beverages suppress D-galactosamine-induced liver injury in rats. J Nutr 129: 1361-1367.
    • (1999) J Nutr , vol.129 , pp. 1361-1367
    • Sugiyama, K.1    He, P.2    Wada, S.3    Saeki, S.4
  • 33
  • 34
    • 0034279858 scopus 로고    scopus 로고
    • Suppression of D-galactosamine-induced liver injury by mushrooms in rats
    • Lee EW, He P, Kawagishi H, Sugiyama K. 2000. Suppression of D-galactosamine-induced liver injury by mushrooms in rats. Biosci Biotechnol Biochem 64: 2001-2004.
    • (2000) Biosci Biotechnol Biochem , vol.64 , pp. 2001-2004
    • Lee, E.W.1    He, P.2    Kawagishi, H.3    Sugiyama, K.4
  • 37
    • 0016180377 scopus 로고
    • Galactosamine hepatitis: Key role of the nucleotide deficiency period in the pathogenesis of cell injury and cell death
    • Decker K, Keppler D. 1974. Galactosamine hepatitis: key role of the nucleotide deficiency period in the pathogenesis of cell injury and cell death. Rev Physiol Biochem Pharmacol 71: 77-106.
    • (1974) Rev Physiol Biochem Pharmacol , vol.71 , pp. 77-106
    • Decker, K.1    Keppler, D.2
  • 38
    • 0037315705 scopus 로고    scopus 로고
    • Immunomodulatory activity of TNF-a during acute liver injury induce by D-galactosamine and its protection by PGE1 in rats
    • Lozano JM, Padillo J, Montero JL, Pena J, De la Mata M, Mutane J. 2003. Immunomodulatory activity of TNF-a during acute liver injury induce by D-galactosamine and its protection by PGE1 in rats. Int Immunopharmacol 3: 197-207.
    • (2003) Int Immunopharmacol , vol.3 , pp. 197-207
    • Lozano, J.M.1    Padillo, J.2    Montero, J.L.3    Pena, J.4    de la Mata, M.5    Mutane, J.6
  • 39
    • 34247481472 scopus 로고    scopus 로고
    • Hepatoprotective effects of a concentrate and components of sake against galactosamine (GalN)-induced liver injury in mice
    • Izu H, Hizume K, Goto K, Hirotsune M. 2007. Hepatoprotective effects of a concentrate and components of sake against galactosamine (GalN)-induced liver injury in mice. Biosci Biotechnol Biochem 71: 951-957.
    • (2007) Biosci Biotechnol Biochem , vol.71 , pp. 951-957
    • Izu, H.1    Hizume, K.2    Goto, K.3    Hirotsune, M.4
  • 40
    • 45449102623 scopus 로고    scopus 로고
    • L-Gln and L-Ser suppress the D-galactosamine-induced IL-18 expression and hepatitis
    • Komano T, Egashira Y, Sanada H. 2008. L-Gln and L-Ser suppress the D-galactosamine-induced IL-18 expression and hepatitis. Biochem Biophys Res Commun 372: 688-690.
    • (2008) Biochem Biophys Res Commun , vol.372 , pp. 688-690
    • Komano, T.1    Egashira, Y.2    Sanada, H.3
  • 41
    • 0037333595 scopus 로고    scopus 로고
    • Role of nitric oxide in D-galactosamine-induced cell death and its protection by PGE1 in cultured hepatocytes
    • Siendones E, Fouad D, Abou-Elella AM, Quintero A, Barrera P, Muntane J. 2003. Role of nitric oxide in D-galactosamine-induced cell death and its protection by PGE1 in cultured hepatocytes. Nitric Oxide 8: 133-143.
    • (2003) Nitric Oxide , vol.8 , pp. 133-143
    • Siendones, E.1    Fouad, D.2    Abou-Elella, A.M.3    Quintero, A.4    Barrera, P.5    Muntane, J.6
  • 42
    • 0038072977 scopus 로고    scopus 로고
    • Carbon tetrachloride-induced lipid peroxidation: Eicosanoid formation and their regulation by antioxidant nutrients
    • Basu S. 2003. Carbon tetrachloride-induced lipid peroxidation: eicosanoid formation and their regulation by antioxidant nutrients. Toxicology 189: 113-127.
    • (2003) Toxicology , vol.189 , pp. 113-127
    • Basu, S.1
  • 45
    • 0033050296 scopus 로고    scopus 로고
    • Role of nitric oxide in lipopolysaccharide-induced hepatic injury in D-galactosamine-sensitized mice as an experimental endotoxin shock model
    • Morikawa A, Kato Y, Sugiyama T, Koide N, Chakravortty D, Yoshida T, Yokochi T. 1999. Role of nitric oxide in lipopolysaccharide-induced hepatic injury in D-galactosamine-sensitized mice as an experimental endotoxin shock model. Infect Immun 67: 1018-1024.
    • (1999) Infect Immun , vol.67 , pp. 1018-1024
    • Morikawa, A.1    Kato, Y.2    Sugiyama, T.3    Koide, N.4    Chakravortty, D.5    Yoshida, T.6    Yokochi, T.7
  • 46
    • 0028999453 scopus 로고
    • Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models
    • Leist M, Gantner F, Bohlinger I, Tiegs G, Germann PG, Wendel A. 1995. Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models. Am J Pathol 146: 1220-1234.
    • (1995) Am J Pathol , vol.146 , pp. 1220-1234
    • Leist, M.1    Gantner, F.2    Bohlinger, I.3    Tiegs, G.4    Germann, P.G.5    Wendel, A.6
  • 48
    • 44149100002 scopus 로고    scopus 로고
    • Protective effect of baicalin against lipopolysaccharide/D-galactosamine-induced liver injury in mice by up-regulation of heme oxygenase-1
    • Wan JY, Gong X, Zhang L, Li HZ, Zhou YF, Zhou QX. 2008. Protective effect of baicalin against lipopolysaccharide/D-galactosamine-induced liver injury in mice by up-regulation of heme oxygenase-1. Eur J Pharmacol 587: 302-308.
    • (2008) Eur J Pharmacol , vol.587 , pp. 302-308
    • Wan, J.Y.1    Gong, X.2    Zhang, L.3    Li, H.Z.4    Zhou, Y.F.5    Zhou, Q.X.6
  • 49
    • 17144430961 scopus 로고    scopus 로고
    • Protective effects of 5,4'-dihydoxy-3',5'-dimethoxy-7-O-ß-D-glucopyranosyl-flavone on experimental hepatic injury
    • Xu DH, Mei XT, Chen Y, Li YM, Lv JY, Xu SB. 2005. Protective effects of 5,4'-dihydoxy-3',5'-dimethoxy-7-O-ß-D-glucopyranosyl-flavone on experimental hepatic injury. World J Gastroenterol 11: 1764-1768.
    • (2005) World J Gastroenterol , vol.11 , pp. 1764-1768
    • Xu, D.H.1    Mei, X.T.2    Chen, Y.3    Li, Y.M.4    Lv, J.Y.5    Xu, S.B.6
  • 50
    • 33748660469 scopus 로고    scopus 로고
    • Beneficial effect of hesperidin on lipopolysaccharide-induced hepatotoxicity
    • Kaur G, Tirkey N, Chopra K. 2006. Beneficial effect of hesperidin on lipopolysaccharide-induced hepatotoxicity. Toxicology 226: 152-160.
    • (2006) Toxicology , vol.226 , pp. 152-160
    • Kaur, G.1    Tirkey, N.2    Chopra, K.3
  • 52
    • 67651250551 scopus 로고    scopus 로고
    • An overview of animal models for investigating the pathogenesis and therapeutic strategies in acute hepatic failure
    • Tunon MJ, Alvarez M, Culebras JM, Gonzlez-Gallego J. 2009. An overview of animal models for investigating the pathogenesis and therapeutic strategies in acute hepatic failure. World J Gastroenterol 15: 3086-3098.
    • (2009) World J Gastroenterol , vol.15 , pp. 3086-3098
    • Tunon, M.J.1    Alvarez, M.2    Culebras, J.M.3    Gonzlez-Gallego, J.4


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