Crystal structure of arginase from plasmodium falciparum and implications for l -arginine depletion in malarial infection

Biochemistry

Volumn 49, Issue 26, 2010, Pages 5600-5608

  Dowling, Daniel P ^a   Ilies, Monica ^a   Olszewski, Kellen L ^b   Portugal, Silvia ^c   Mota, Maria M ^c   Llinás, Manuel ^b   Christianson, David W ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b PRINCETON UNIVERSITY   (United States)

^c UNIVERSITY OF LISBON   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL THERAPY; BORONIC ACID; ENZYME FUNCTIONS; IN-VIVO; INTERMOLECULAR INTERACTIONS; L-ARGININE; LOW-COMPLEXITY; PARASITE-; PLASMODIUM FALCIPARUM; STRUCTURAL STUDIES;

ACIDS; AMINO ACIDS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYMES; LIVER;

CRYSTAL STRUCTURE;

2 AMINO 6 BORONOHEXANOIC ACID; ARGINASE; ARGININE; ARGININE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME STRUCTURE; HEPATITIS; IN VIVO STUDY; MALARIA FALCIPARUM; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; SPOROZOITE;

ARGINASE; ARGININE; CRYSTALLOGRAPHY, X-RAY; HUMANS; LIVER; MALARIA; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PROTEIN CONFORMATION; SPOROZOITES;

PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM;

EID: 77954199478     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100390z     Document Type: Article

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