The activity of Plasmodium falciparum arginase is mediated by a novel inter-monomer salt-bridge between Glu295-Arg404

FEBS Journal

Volumn 276, Issue 13, 2009, Pages 3517-3530

  Wells, Gordon A ^a   Müller, Ingrid B ^b   Wrenger, Carsten ^b   Louw, Abraham I ^a  

^a UNIVERSITY OF PRETORIA   (South Africa)

^b BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

Author keywords

Arginase; Malaria; Metal; Modelling; Trimer

Indexed keywords

MONOMER; PLASMODIUM FALCIPARUM ARGINASE; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER MODEL; ENZYME ACTIVITY; ENZYME INHIBITION; MOLECULAR DYNAMICS; MUTATIONAL ANALYSIS; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN STABILITY; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; ARGINASE; ARGININE; CATALYTIC DOMAIN; HUMANS; MAGNESIUM; MANGANESE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PLASMODIUM FALCIPARUM; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; RATS; SALTS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

MAMMALIA; PLASMODIUM FALCIPARUM;

EID: 67650501028     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07073.x     Document Type: Article

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