Inhibition of Mn2+2-arginase by borate leads to the design of a transition state analogue inhibitor, 2(S)-amino-6-boronohexanoic acid

Journal of the American Chemical Society

Volumn 119, Issue 34, 1997, Pages 8107-8108

  Baggio, R ^a   Elbaum, D ^a   Kanyo, Z F ^a   Carroll, P J ^a   Cavalli, R C ^a   Ash, D E ^a   Christianson, D W ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE; BORIC ACID; BORONIC ACID DERIVATIVE;

ARTICLE; CRYSTAL STRUCTURE; DRUG DESIGN; ENZYME INHIBITION; ENZYME SUBSTRATE COMPLEX; HYDROLYSIS; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

EID: 0030768666     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja971312d     Document Type: Article

References (22)