메뉴 건너뛰기




Volumn 60, Issue 12, 2000, Pages 3305-3312

Activity in human breast cancer cell lines: N(ω)-hydroxy-L-arginine selectively inhibits cell proliferation and induces apoptosis in MDA-MB-468 cells

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE; ARGININE; N(G) HYDROXYARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; ORNITHINE; POLYAMINE; PROTEIN P21; SPERMINE; CASP3 PROTEIN, HUMAN; CASPASE; CASPASE 3; DNA FRAGMENT; DRUG DERIVATIVE; ENZYME INHIBITOR; N(OMEGA) HYDROXYARGININE; N(OMEGA)-HYDROXYARGININE;

EID: 0034658924     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (185)

References (49)
  • 2
    • 0020215250 scopus 로고
    • Polyamine metabolism and function
    • Pegg, A. E. Polyamine metabolism and function. Am. J. Physiol., 243: C212-C221, 1982.
    • (1982) Am. J. Physiol. , vol.243
    • Pegg, A.E.1
  • 3
    • 0023908016 scopus 로고
    • Polyamines in relation to human breast, rectal and squamous cell carcinoma
    • Chanda, R., and Ganguly, A. K. Polyamines in relation to human breast, rectal and squamous cell carcinoma. Cancer Lett., 39: 311-318, 1988.
    • (1988) Cancer Lett. , vol.39 , pp. 311-318
    • Chanda, R.1    Ganguly, A.K.2
  • 4
    • 0024893739 scopus 로고
    • Polyamines and hormonal control of breast cancer growth
    • Manni, A. Polyamines and hormonal control of breast cancer growth. Crit. Rev. Oncog., 1: 163-174, 1989.
    • (1989) Crit. Rev. Oncog. , vol.1 , pp. 163-174
    • Manni, A.1
  • 5
    • 0021349357 scopus 로고
    • Reversal of the antiproliferative effect of the antiestrogen tamoxifen by polyamines in breast cancer cells
    • Manni, A., and Wright, C. Reversal of the antiproliferative effect of the antiestrogen tamoxifen by polyamines in breast cancer cells. Endocrinology, 114: 836-839, 1984.
    • (1984) Endocrinology , vol.114 , pp. 836-839
    • Manni, A.1    Wright, C.2
  • 6
    • 0026336186 scopus 로고
    • Human colorectal adenocarcinoma cells: Differential nitric oxide synthesis determines their ability to aggregate platelets
    • Radomski, M. W., Jenkins, D. C., Holmes, L., and Moncada, S. Human colorectal adenocarcinoma cells: differential nitric oxide synthesis determines their ability to aggregate platelets. Cancer Res., 51: 6073-6078, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 6073-6078
    • Radomski, M.W.1    Jenkins, D.C.2    Holmes, L.3    Moncada, S.4
  • 7
    • 0027974255 scopus 로고
    • Human colon cancer cell lines show a diverse pattern of nitric oxide synthase gene expression and nitric oxide generation
    • Jenkins, D., C., Charles, I. G., Baylis, S. A., Lelchuk, R., Radomski, M. W., and Moncada, S. Human colon cancer cell lines show a diverse pattern of nitric oxide synthase gene expression and nitric oxide generation. Br. J. Cancer, 70: 847-849, 1994.
    • (1994) Br. J. Cancer , vol.70 , pp. 847-849
    • Jenkins, D.C.1    Charles, I.G.2    Baylis, S.A.3    Lelchuk, R.4    Radomski, M.W.5    Moncada, S.6
  • 12
    • 0029951079 scopus 로고    scopus 로고
    • Tumor cell nitric oxide inhibits cell growth in vitro, but stimulates tumorigenesis and experimental lung metastasis in vivo
    • Edwards, P., Cendan, J. C., Topping, D. B., Moldawer, L. L., MacKay, S., Copeland, E. M. III, and Lind, D. S. Tumor cell nitric oxide inhibits cell growth in vitro, but stimulates tumorigenesis and experimental lung metastasis in vivo. J. Surg. Res., 63: 49-52, 1996.
    • (1996) J. Surg. Res. , vol.63 , pp. 49-52
    • Edwards, P.1    Cendan, J.C.2    Topping, D.B.3    Moldawer, L.L.4    Mackay, S.5    Copeland E.M. III6    Lind, D.S.7
  • 14
    • 0028814494 scopus 로고
    • Antiproliferative effect of spermine depletion by N-cyclohexyl-1,3-diaminopropane in human breast cancer cells
    • Huber, M., and Poulin, R. Antiproliferative effect of spermine depletion by N-cyclohexyl-1,3-diaminopropane in human breast cancer cells. Cancer Res., 55: 934-943, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 934-943
    • Huber, M.1    Poulin, R.2
  • 15
    • 0028302827 scopus 로고
    • Activated murine macrophages induce apoptosis in tumor cells through nitric oxide dependent or independent mechanisms
    • Cui, S., Reichner, J. S., Mateo, R. B., and Albina, J. E. Activated murine macrophages induce apoptosis in tumor cells through nitric oxide dependent or independent mechanisms. Cancer Res., 54: 2462-2467, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 2462-2467
    • Cui, S.1    Reichner, J.S.2    Mateo, R.B.3    Albina, J.E.4
  • 16
    • 0028026967 scopus 로고
    • Inhibition of rat liver arginase by an intermediate in NO biosynthesis, NG-hydroxy-L-arginine: Implications for the regulation of nitric oxide biosynthesis by arginase
    • Daghigh, F., Fukuto, J. M., and Ash, D. E. Inhibition of rat liver arginase by an intermediate in NO biosynthesis, NG-hydroxy-L-arginine: implications for the regulation of nitric oxide biosynthesis by arginase. Biochem. Biophys. Res. Commun., 202: 174-180, 1994.
    • (1994) Biochem. Biophys. Res. Commun. , vol.202 , pp. 174-180
    • Daghigh, F.1    Fukuto, J.M.2    Ash, D.E.3
  • 17
    • 0028985126 scopus 로고
    • Inhibition of arginase by NG-hydroxy-L-arginine in alveolar macrophages: Implications for the utilization of L-arginine for nitric oxide synthesis
    • Hecker, M., Nematollahi, H., Hey, C., Busse, R., and Racke, K. Inhibition of arginase by NG-hydroxy-L-arginine in alveolar macrophages: implications for the utilization of L-arginine for nitric oxide synthesis. FEBS Lett., 359: 251-254, 1995.
    • (1995) FEBS Lett. , vol.359 , pp. 251-254
    • Hecker, M.1    Nematollahi, H.2    Hey, C.3    Busse, R.4    Racke, K.5
  • 19
    • 0023881236 scopus 로고
    • Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy
    • Pegg, A. E. Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy. Cancer Res., 48: 759-767, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 759-767
    • Pegg, A.E.1
  • 21
    • 0018899877 scopus 로고
    • Comparative properties of fetal and adult red blood cell arginase: A possible prenatal diagnostic test for arginase deficiency
    • Spector, E. B., Kiernan, M., Bernard, B., and Cederbaum, S. D. Comparative properties of fetal and adult red blood cell arginase: a possible prenatal diagnostic test for arginase deficiency. Am. J. Hum. Genet., 32: 79-87, 1980.
    • (1980) Am. J. Hum. Genet. , vol.32 , pp. 79-87
    • Spector, E.B.1    Kiernan, M.2    Bernard, B.3    Cederbaum, S.D.4
  • 23
    • 0031587772 scopus 로고    scopus 로고
    • Evidence for the presence of unusual nitric oxide and citrulline-producing enzyme in rat kidney
    • Singh, R., Pervin, S., Rogers, N. S., Ignarro, L. J., and Chaudhuri, G. Evidence for the presence of unusual nitric oxide and citrulline-producing enzyme in rat kidney. Biochem. Biophys. Res. Commun., 232: 672-677, 1997.
    • (1997) Biochem. Biophys. Res. Commun. , vol.232 , pp. 672-677
    • Singh, R.1    Pervin, S.2    Rogers, N.S.3    Ignarro, L.J.4    Chaudhuri, G.5
  • 27
    • 0022423245 scopus 로고
    • Isolation and characterization of rat and human glyceraldehyde 3-phosphate dehydrogenase cDNAs: Genomic complexity and molecular evolution of the gene
    • Tso, J. Y., Sun, X. H., Kao, T. H., Reece, K. S., and Wu, R. Isolation and characterization of rat and human glyceraldehyde 3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene. Nucleic Acids Res., 13: 2485-2502, 1985.
    • (1985) Nucleic Acids Res. , vol.13 , pp. 2485-2502
    • Tso, J.Y.1    Sun, X.H.2    Kao, T.H.3    Reece, K.S.4    Wu, R.5
  • 28
    • 0026672842 scopus 로고
    • Indirect photometric detection of polyamines in biological samples separated by high performance capillary electrophoresis
    • Ma, Y., Zhang, R., and Cooper, C. L. Indirect photometric detection of polyamines in biological samples separated by high performance capillary electrophoresis. J. Chromatogr., 608: 93-96, 1992.
    • (1992) J. Chromatogr. , vol.608 , pp. 93-96
    • Ma, Y.1    Zhang, R.2    Cooper, C.L.3
  • 29
    • 0029916201 scopus 로고    scopus 로고
    • Detection of apoptosis at the single-cell level by direct incorporation of fluorescein-dUTP in DNA strand breaks
    • Piqueras, B., Autran, B., Debre, P., and Gorochov, G. Detection of apoptosis at the single-cell level by direct incorporation of fluorescein-dUTP in DNA strand breaks. Biotechniques, 20: 634-640, 1996.
    • (1996) Biotechniques , vol.20 , pp. 634-640
    • Piqueras, B.1    Autran, B.2    Debre, P.3    Gorochov, G.4
  • 32
    • 0028902552 scopus 로고
    • Nitric-oxide synthases: Properties and catalytic mechanism
    • Griffith, O. W., and Sluehr, D. J. Nitric-oxide synthases: properties and catalytic mechanism. Annu. Rev. Physiol., 57: 707-736, 1995.
    • (1995) Annu. Rev. Physiol. , vol.57 , pp. 707-736
    • Griffith, O.W.1    Sluehr, D.J.2
  • 33
    • 0024584020 scopus 로고
    • Nitric oxide: A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells
    • Stuehr, D. J., and Nathan, C. F. Nitric oxide: a macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J. Exp. Med., 169: 1543-1555, 1989.
    • (1989) J. Exp. Med. , vol.169 , pp. 1543-1555
    • Stuehr, D.J.1    Nathan, C.F.2
  • 34
    • 0027980511 scopus 로고
    • Quenching of the tyrosyl free radical of ribonucleotide reductase by nitric oxide: Relationship to cytostasis induced in tumor cells by cytotoxic macrophages
    • Lepoivre, M., Flaman, J. M., Bobae, P., Lemaire, G., and Henry, Y. Quenching of the tyrosyl free radical of ribonucleotide reductase by nitric oxide: relationship to cytostasis induced in tumor cells by cytotoxic macrophages. J. Biol. Chem., 269: 21891-21897, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 21891-21897
    • Lepoivre, M.1    Flaman, J.M.2    Bobae, P.3    Lemaire, G.4    Henry, Y.5
  • 36
    • 0026722310 scopus 로고
    • Macrophage arginine metabolism and the inhibition or stimulation of cancer
    • Mills, C. D., Shearer, J., Evans, R., and Caldwell, M. D. Macrophage arginine metabolism and the inhibition or stimulation of cancer. J. Immunol., 149: 2709-2714, 1992.
    • (1992) J. Immunol. , vol.149 , pp. 2709-2714
    • Mills, C.D.1    Shearer, J.2    Evans, R.3    Caldwell, M.D.4
  • 37
    • 0029047967 scopus 로고
    • Characterization of the stable L-arginine-derived relaxing factor released from cytokine-stimulated vascular smooth muscle cells as a NG-hydroxy-L-arginine-nitric oxide adduct
    • Hecker, M., Boese, M., Schini-Kerth, V. B., Mulsch, A., and Busse, R. Characterization of the stable L-arginine-derived relaxing factor released from cytokine-stimulated vascular smooth muscle cells as a NG-hydroxy-L-arginine-nitric oxide adduct. Proc. Natl. Acad. Sci. USA, 92: 4671-4675, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 4671-4675
    • Hecker, M.1    Boese, M.2    Schini-Kerth, V.B.3    Mulsch, A.4    Busse, R.5
  • 39
    • 0032186365 scopus 로고    scopus 로고
    • NG-Hydroxy-L-arginine and nitric oxide inhibit Caco-2 tumor cell proliferation by distinct mechanisms
    • Buga, G. M., Wei, L. H., Bauer, P. M., Fukuto, J. M., and Ignarro, L. J. NG-Hydroxy-L-arginine and nitric oxide inhibit Caco-2 tumor cell proliferation by distinct mechanisms. Am. J. Physiol., 275: RI256-RI264, 1998.
    • (1998) Am. J. Physiol. , vol.275
    • Buga, G.M.1    Wei, L.H.2    Bauer, P.M.3    Fukuto, J.M.4    Ignarro, L.J.5
  • 40
    • 0028985403 scopus 로고
    • Increase in serum NG-hydroxy-L-arginine in rats treated with bacterial lipopolysaccharide
    • Hecker, M., Scott, C., Bucher, B., Busse, R., and Stoclet, J. C. Increase in serum NG-hydroxy-L-arginine in rats treated with bacterial lipopolysaccharide. Eur. J. Pharmacol., 275: R1-R3, 1995.
    • (1995) Eur. J. Pharmacol. , vol.275
    • Hecker, M.1    Scott, C.2    Bucher, B.3    Busse, R.4    Stoclet, J.C.5
  • 41
    • 0032927809 scopus 로고    scopus 로고
    • Effect of epidermal growth factor on MDA-MB-468 breast cancer cells: Alterations in polyamine biosynthesis and the expression of p21/CIP1/WAF1
    • Thomas, T., Balabhadrapathruni, S., Gardner, C. R., Hong, J., Faaland, C. A., and Thomas, T. J. Effect of epidermal growth factor on MDA-MB-468 breast cancer cells: Alterations in polyamine biosynthesis and the expression of p21/CIP1/WAF1, J. Cell. Physiol., 179: 257-266, 1999.
    • (1999) J. Cell. Physiol. , vol.179 , pp. 257-266
    • Thomas, T.1    Balabhadrapathruni, S.2    Gardner, C.R.3    Hong, J.4    Faaland, C.A.5    Thomas, T.J.6
  • 42
    • 0029661914 scopus 로고    scopus 로고
    • 1/S transition and prolonged S phase within one cell cycle after seeding cells in the presence of an ornithine decarboxylase inhibitor
    • 1/S transition and prolonged S phase within one cell cycle after seeding cells in the presence of an ornithine decarboxylase inhibitor. Cell Prolif., 29: 457-466, 1996.
    • (1996) Cell Prolif. , vol.29 , pp. 457-466
    • Fredlund, J.O.1    Oredsson, S.M.2
  • 43
    • 0028169236 scopus 로고
    • p21-containing cyclin kinases exist in both active and inactive states
    • Zhang, H., Hannon, G. J., and Beach, D. p21-containing cyclin kinases exist in both active and inactive states. Genes Dev., 8: 1750-1758, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 1750-1758
    • Zhang, H.1    Hannon, G.J.2    Beach, D.3
  • 46
    • 0023881236 scopus 로고
    • Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy
    • Pegg, A. E. Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy. Cancer Res., 48: 759-774, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 759-774
    • Pegg, A.E.1
  • 47
    • 0002861247 scopus 로고
    • Modulation of antineoplastic drug action by inhibitors of polyamine biosynthesis
    • P. P. McCann, A. E. Pegg, and A. Sjoerdsma, (eds.), New York: Academic Press
    • Porter, C. W., and Janne, J. Modulation of antineoplastic drug action by inhibitors of polyamine biosynthesis. In: P. P. McCann, A. E. Pegg, and A. Sjoerdsma, (eds.), Inhibition of Polyamine Metabolism: Biological Significance and Basis for New Therapies, pp. 203-248. New York: Academic Press, 1987.
    • (1987) Inhibition of Polyamine Metabolism: Biological Significance and Basis for New Therapies , pp. 203-248
    • Porter, C.W.1    Janne, J.2
  • 48
    • 0025823758 scopus 로고
    • Spermine prevents endonuclease activation and apoptosis in thymocytes
    • Brüne, B., Hartzell, P., Nicotera, P., and Orrenius, S. Spermine prevents endonuclease activation and apoptosis in thymocytes. Exp. Cell Res., 195: 323-329, 1991.
    • (1991) Exp. Cell Res. , vol.195 , pp. 323-329
    • Brüne, B.1    Hartzell, P.2    Nicotera, P.3    Orrenius, S.4
  • 49
    • 0032081543 scopus 로고    scopus 로고
    • Involvement of apoptosis and cyclin D1 gene repression in growth inhibition of T-47D human breast cancer cells by methylglyoxal bis(cyclopentylamidinohydrazone)
    • Kaneko, H., Hibasami, H., Satoh, N., Wakabayashi, H., Ikeda, H., Tsuge, N., Yonemaru, K., Muraki, A., Kawarada, Y., and Nakashima, K. Involvement of apoptosis and cyclin D1 gene repression in growth inhibition of T-47D human breast cancer cells by methylglyoxal bis(cyclopentylamidinohydrazone). Int. J. Mol. Med., 1: 931-936, 1998.
    • (1998) Int. J. Mol. Med. , vol.1 , pp. 931-936
    • Kaneko, H.1    Hibasami, H.2    Satoh, N.3    Wakabayashi, H.4    Ikeda, H.5    Tsuge, N.6    Yonemaru, K.7    Muraki, A.8    Kawarada, Y.9    Nakashima, K.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.