The efficacy of siRNAs against hepatitis C virus is strongly influenced by structure and target site accessibility

Chemistry and Biology

Volumn 17, Issue 5, 2010, Pages 515-527

  Sagan, Selena M ^a,c   Nasheri, Neda ^a   Luebbert, Christian ^a   Pezacki, John Paul ^a,b  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SMALL INTERFERING RNA; VIRUS RNA;

ARTICLE; CHEMISTRY; CONFORMATION; DRUG EFFECT; GENE SILENCING; GENETICS; HEPATITIS C VIRUS; HUMAN; MAGNETISM; METABOLISM; NUCLEIC ACID HYBRIDIZATION; RNA INTERFERENCE; TUMOR CELL LINE; VIRUS REPLICATION;

CELL LINE, TUMOR; GENE KNOCKDOWN TECHNIQUES; HEPACIVIRUS; HUMANS; MAGNETICS; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HYBRIDIZATION; RNA INTERFERENCE; RNA, SMALL INTERFERING; RNA, VIRAL; VIRUS REPLICATION;

HEPATITIS C VIRUS;

EID: 77954195219     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2010.04.011     Document Type: Article

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