-
1
-
-
42949146633
-
Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin
-
López M, Lage R, Saha AK, Pérez-Tilve D, Vázquez MJ, Varela L, Sangiao-Alvarellos S, Tovar S, Raghay K, Rodríguez-Cuenca S, Deoliveira RM, Castañeda T, Datta R, Dong JZ, Culler M, Sleeman MW, Álvarez CV, Gallego R, Lelliott CJ, Carling D, Tschop MH, Diéguez C, Vidal-Puig A. Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin. Cell Metab 2008, 7:389-399.
-
(2008)
Cell Metab
, vol.7
, pp. 389-399
-
-
López, M.1
Lage, R.2
Saha, A.K.3
Pérez-Tilve, D.4
Vázquez, M.J.5
Varela, L.6
Sangiao-Alvarellos, S.7
Tovar, S.8
Raghay, K.9
Rodríguez-Cuenca, S.10
Deoliveira, R.M.11
Castañeda, T.12
Datta, R.13
Dong, J.Z.14
Culler, M.15
Sleeman, M.W.16
Álvarez, C.V.17
Gallego, R.18
Lelliott, C.J.19
Carling, D.20
Tschop, M.H.21
Diéguez, C.22
Vidal-Puig, A.23
more..
-
2
-
-
33745294817
-
Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA
-
López M, Lelliott CJ, Tovar S, Kimber W, Gallego R, Virtue S, Blount M, Vázquez MJ, Finer N, Powles TJ, O'Rahilly S, Saha AK, Diéguez C, Vidal-Puig AJ. Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA. Diabetes 2006, 55:1327-1336.
-
(2006)
Diabetes
, vol.55
, pp. 1327-1336
-
-
López, M.1
Lelliott, C.J.2
Tovar, S.3
Kimber, W.4
Gallego, R.5
Virtue, S.6
Blount, M.7
Vázquez, M.J.8
Finer, N.9
Powles, T.J.10
O'Rahilly, S.11
Saha, A.K.12
Diéguez, C.13
Vidal-Puig, A.J.14
-
3
-
-
0038037734
-
Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production
-
Obici S, Feng Z, Arduini A, Conti R, Rossetti L. Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production. Nat Med 2003, 9:756-761.
-
(2003)
Nat Med
, vol.9
, pp. 756-761
-
-
Obici, S.1
Feng, Z.2
Arduini, A.3
Conti, R.4
Rossetti, L.5
-
4
-
-
33845998567
-
The role of hypothalamic malonyl-CoA in energy homeostasis
-
Wolfgang MJ, Lane MD. The role of hypothalamic malonyl-CoA in energy homeostasis. J Biol Chem 2006, 281:37265-37269.
-
(2006)
J Biol Chem
, vol.281
, pp. 37265-37269
-
-
Wolfgang, M.J.1
Lane, M.D.2
-
5
-
-
1842484296
-
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
-
Minokoshi Y, Alquier T, Furukawa N, Kim YB, Lee A, Xue B, Mu J, Foufelle F, Ferre P, Birnbaum MJ, Stuck BJ, Kahn BB. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 2004, 428:569-574.
-
(2004)
Nature
, vol.428
, pp. 569-574
-
-
Minokoshi, Y.1
Alquier, T.2
Furukawa, N.3
Kim, Y.B.4
Lee, A.5
Xue, B.6
Mu, J.7
Foufelle, F.8
Ferre, P.9
Birnbaum, M.J.10
Stuck, B.J.11
Kahn, B.B.12
-
6
-
-
1842582870
-
AMP-activated protein kinase plays a role in the control of food intake
-
Andersson U, Filipsson K, Abbott CR, Woods A, Smith K, Bloom SR, Carling D, Small CJ. AMP-activated protein kinase plays a role in the control of food intake. J Biol Chem 2004, 279:12005-12008.
-
(2004)
J Biol Chem
, vol.279
, pp. 12005-12008
-
-
Andersson, U.1
Filipsson, K.2
Abbott, C.R.3
Woods, A.4
Smith, K.5
Bloom, S.R.6
Carling, D.7
Small, C.J.8
-
7
-
-
37649003524
-
Regulation of hypothalamic malonyl-CoA by central glucose and leptin
-
Wolfgang MJ, Cha SH, Sidhaye A, Chohnan S, Cline G, Shulman GI, Lane MD. Regulation of hypothalamic malonyl-CoA by central glucose and leptin. Proc Natl Acad Sci USA 2007, 104:19285-19290.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19285-19290
-
-
Wolfgang, M.J.1
Cha, S.H.2
Sidhaye, A.3
Chohnan, S.4
Cline, G.5
Shulman, G.I.6
Lane, M.D.7
-
8
-
-
55049140818
-
Acute effects of glucagon-like peptide-1 on hypothalamic neuropeptide and AMP activated kinase expression in fasted rats
-
Seo S, Ju S, Chung H, Lee D, Park S. Acute effects of glucagon-like peptide-1 on hypothalamic neuropeptide and AMP activated kinase expression in fasted rats. Endocr J 2008, 55:867-874.
-
(2008)
Endocr J
, vol.55
, pp. 867-874
-
-
Seo, S.1
Ju, S.2
Chung, H.3
Lee, D.4
Park, S.5
-
9
-
-
21644453934
-
Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase
-
Kola B, Hubina E, Tucci SA, Kirkham TC, Garcia EA, Mitchell SE, Williams LM, Hawley SA, Hardie DG, Grossman AB, Korbonits M. Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase. J Biol Chem 2005, 280:25196-25201.
-
(2005)
J Biol Chem
, vol.280
, pp. 25196-25201
-
-
Kola, B.1
Hubina, E.2
Tucci, S.A.3
Kirkham, T.C.4
Garcia, E.A.5
Mitchell, S.E.6
Williams, L.M.7
Hawley, S.A.8
Hardie, D.G.9
Grossman, A.B.10
Korbonits, M.11
-
10
-
-
49649122302
-
UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals
-
Andrews ZB, Liu ZW, Walllingford N, Erion DM, Borok E, Friedman JM, Tschop MH, Shanabrough M, Cline G, Shulman GI, Coppola A, Gao XB, Horvath TL, Diano S. UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals. Nature 2008, 454:846-851.
-
(2008)
Nature
, vol.454
, pp. 846-851
-
-
Andrews, Z.B.1
Liu, Z.W.2
Walllingford, N.3
Erion, D.M.4
Borok, E.5
Friedman, J.M.6
Tschop, M.H.7
Shanabrough, M.8
Cline, G.9
Shulman, G.I.10
Coppola, A.11
Gao, X.B.12
Horvath, T.L.13
Diano, S.14
-
11
-
-
40749132626
-
Key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia
-
McCrimmon RJ, Shaw M, Fan X, Cheng H, Ding Y, Vella MC, Zhou L, McNay EC, Sherwin RS. Key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia. Diabetes 2008, 57:444-450.
-
(2008)
Diabetes
, vol.57
, pp. 444-450
-
-
McCrimmon, R.J.1
Shaw, M.2
Fan, X.3
Cheng, H.4
Ding, Y.5
Vella, M.C.6
Zhou, L.7
McNay, E.C.8
Sherwin, R.S.9
-
12
-
-
47849091265
-
Intracerebroventricular injection of citrate inhibits hypothalamic AMPK and modulates feeding behavior and peripheral insulin signaling
-
Stoppa GR, Cesquini M, Roman EA, Prada PO, Torsoni AS, Romanatto T, Saad MJ, Velloso LA, Torsoni MA. Intracerebroventricular injection of citrate inhibits hypothalamic AMPK and modulates feeding behavior and peripheral insulin signaling. J Endocrinol 2008, 198:157-168.
-
(2008)
J Endocrinol
, vol.198
, pp. 157-168
-
-
Stoppa, G.R.1
Cesquini, M.2
Roman, E.A.3
Prada, P.O.4
Torsoni, A.S.5
Romanatto, T.6
Saad, M.J.7
Velloso, L.A.8
Torsoni, M.A.9
-
13
-
-
0033540056
-
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
-
Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999, 402:656-660.
-
(1999)
Nature
, vol.402
, pp. 656-660
-
-
Kojima, M.1
Hosoda, H.2
Date, Y.3
Nakazato, M.4
Matsuo, H.5
Kangawa, K.6
-
14
-
-
29044434688
-
Expression of ghrelin receptor mRNA in the rat and the mouse brain
-
Zigman JM, Jones JE, Lee CE, Saper CB, Elmquist JK. Expression of ghrelin receptor mRNA in the rat and the mouse brain. J Comp Neurol 2006, 494:528-548.
-
(2006)
J Comp Neurol
, vol.494
, pp. 528-548
-
-
Zigman, J.M.1
Jones, J.E.2
Lee, C.E.3
Saper, C.B.4
Elmquist, J.K.5
-
15
-
-
9444246501
-
A receptor in pituitary and hypothalamus that functions in growth hormone release
-
Howard AD, Feighner SD, Cully DF, Arena JP, Liberator PA, Rosenblum CI, Hamelin M, Hreniuk DL, Palyha OC, Anderson J, Paress PS, Diaz C, Chou M, Liu KK, McKee KK, Pong SS, Chaung LY, Elbrecht A, Dashkevicz M, Heavens R, Rigby M, Sirinathsinghji DJ, Dean DC, Melillo DG, Patchett AA, Nargund R, Griffin PR, DeMartino JA, Gupta SK, Schaeffer JM, Smith RG, Van der Ploeg LH. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science 1996, 273:974-977.
-
(1996)
Science
, vol.273
, pp. 974-977
-
-
Howard, A.D.1
Feighner, S.D.2
Cully, D.F.3
Arena, J.P.4
Liberator, P.A.5
Rosenblum, C.I.6
Hamelin, M.7
Hreniuk, D.L.8
Palyha, O.C.9
Anderson, J.10
Paress, P.S.11
Diaz, C.12
Chou, M.13
Liu, K.K.14
McKee, K.K.15
Pong, S.S.16
Chaung, L.Y.17
Elbrecht, A.18
Dashkevicz, M.19
Heavens, R.20
Rigby, M.21
Sirinathsinghji, D.J.22
Dean, D.C.23
Melillo, D.G.24
Patchett, A.A.25
Nargund, R.26
Griffin, P.R.27
DeMartino, J.A.28
Gupta, S.K.29
Schaeffer, J.M.30
Smith, R.G.31
Van der Ploeg, L.H.32
more..
-
16
-
-
0034687376
-
Ghrelin induces adiposity in rodents
-
Tschop M, Smiley DL, Heiman ML. Ghrelin induces adiposity in rodents. Nature 2000, 407:908-913.
-
(2000)
Nature
, vol.407
, pp. 908-913
-
-
Tschop, M.1
Smiley, D.L.2
Heiman, M.L.3
-
17
-
-
0035433977
-
A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
-
Cummings DE, Purnell JQ, Frayo RS, Schmidova K, Wisse BE, Weigle DS. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 2001, 50:1714-1719.
-
(2001)
Diabetes
, vol.50
, pp. 1714-1719
-
-
Cummings, D.E.1
Purnell, J.Q.2
Frayo, R.S.3
Schmidova, K.4
Wisse, B.E.5
Weigle, D.S.6
-
18
-
-
45549092924
-
The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system
-
Kola B, Farkas I, Christ-Crain M, Wittmann G, Lolli F, Amin F, Harvey-White J, Liposits Z, Kunos G, Grossman AB, Fekete C, Korbonits M. The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system. PLoS ONE 2008, 3:e1797.
-
(2008)
PLoS ONE
, vol.3
-
-
Kola, B.1
Farkas, I.2
Christ-Crain, M.3
Wittmann, G.4
Lolli, F.5
Amin, F.6
Harvey-White, J.7
Liposits, Z.8
Kunos, G.9
Grossman, A.B.10
Fekete, C.11
Korbonits, M.12
-
19
-
-
33745834734
-
Ghrelin action in the brain controls adipocyte metabolism
-
Theander-Carrillo C, Wiedmer P, Cettour-Rose P, Nogueiras R, Perez-Tilve D, Pfluger P, Castaneda TR, Muzzin P, Schurmann A, Szanto I, Tschop MH, Rohner-Jeanrenaud F. Ghrelin action in the brain controls adipocyte metabolism. J Clin Invest 2006, 116:1983-1993.
-
(2006)
J Clin Invest
, vol.116
, pp. 1983-1993
-
-
Theander-Carrillo, C.1
Wiedmer, P.2
Cettour-Rose, P.3
Nogueiras, R.4
Perez-Tilve, D.5
Pfluger, P.6
Castaneda, T.R.7
Muzzin, P.8
Schurmann, A.9
Szanto, I.10
Tschop, M.H.11
Rohner-Jeanrenaud, F.12
-
20
-
-
70349326314
-
Central ghrelin regulates peripheral lipid metabolism in a growth hormone-independent fashion
-
Sangiao-Alvarellos S, Vázquez MJ, Varela L, Nogueiras R, Saha AK, Cordido F, López M, Diéguez C. Central ghrelin regulates peripheral lipid metabolism in a growth hormone-independent fashion. Endocrinology 2009, 150:4562-4574.
-
(2009)
Endocrinology
, vol.150
, pp. 4562-4574
-
-
Sangiao-Alvarellos, S.1
Vázquez, M.J.2
Varela, L.3
Nogueiras, R.4
Saha, A.K.5
Cordido, F.6
López, M.7
Diéguez, C.8
-
21
-
-
0025059412
-
Influence of food deprivation in the rat on hypothalamic expression of growth hormone-releasing factor and somatostatin
-
Bruno JF, Olchovsky D, White JD, Leidy JW, Song J, Berelowitz M. Influence of food deprivation in the rat on hypothalamic expression of growth hormone-releasing factor and somatostatin. Endocrinology 1990, 127:2111-2116.
-
(1990)
Endocrinology
, vol.127
, pp. 2111-2116
-
-
Bruno, J.F.1
Olchovsky, D.2
White, J.D.3
Leidy, J.W.4
Song, J.5
Berelowitz, M.6
-
22
-
-
0034507983
-
Ghrelin-induced growth hormone secretion in humans
-
Peino R, Baldelli R, Rodríguez-García J, Rodríguez-Segade S, Kojima M, Kangawa K, Arvat E, Ghigo E, Diéguez C, Casanueva FF. Ghrelin-induced growth hormone secretion in humans. Eur J Endocrinol 2000, 143:R11-R14.
-
(2000)
Eur J Endocrinol
, vol.143
-
-
Peino, R.1
Baldelli, R.2
Rodríguez-García, J.3
Rodríguez-Segade, S.4
Kojima, M.5
Kangawa, K.6
Arvat, E.7
Ghigo, E.8
Diéguez, C.9
Casanueva, F.F.10
-
23
-
-
0030732108
-
Hypothalamic growth hormone secretagogue-receptor (GHS-R) expression is regulated by growth hormone in the rat
-
Bennett PA, Thomas GB, Howard AD, Feighner SD, van der Ploeg LH, Smith RG, Robinson IC. Hypothalamic growth hormone secretagogue-receptor (GHS-R) expression is regulated by growth hormone in the rat. Endocrinology 1997, 138:4552-4557.
-
(1997)
Endocrinology
, vol.138
, pp. 4552-4557
-
-
Bennett, P.A.1
Thomas, G.B.2
Howard, A.D.3
Feighner, S.D.4
van der Ploeg, L.H.5
Smith, R.G.6
Robinson, I.C.7
-
24
-
-
33644855561
-
Growth hormone receptor deficiency results in blunted ghrelin feeding response, obesity, and hypolipidemia in mice
-
Egecioglu E, Bjursell M, Ljungberg A, Dickson SL, Kopchick JJ, Bergstrom G, Svensson L, Oscarsson J, Tornell J, Bohlooly YM. Growth hormone receptor deficiency results in blunted ghrelin feeding response, obesity, and hypolipidemia in mice. Am J Physiol Endocrinol Metab 2006, 290:E317-E325.
-
(2006)
Am J Physiol Endocrinol Metab
, vol.290
-
-
Egecioglu, E.1
Bjursell, M.2
Ljungberg, A.3
Dickson, S.L.4
Kopchick, J.J.5
Bergstrom, G.6
Svensson, L.7
Oscarsson, J.8
Tornell, J.9
Bohlooly, Y.M.10
-
25
-
-
0023770734
-
Growth hormone-deficient dwarfism in the rat: a new mutation
-
Charlton HM, Clark RG, Robinson IC, Goff AE, Cox BS, Bugnon C, Bloch BA. Growth hormone-deficient dwarfism in the rat: a new mutation. J Endocrinol 1988, 119:51-58.
-
(1988)
J Endocrinol
, vol.119
, pp. 51-58
-
-
Charlton, H.M.1
Clark, R.G.2
Robinson, I.C.3
Goff, A.E.4
Cox, B.S.5
Bugnon, C.6
Bloch, B.A.7
-
26
-
-
50449106902
-
Central resistin regulates hypothalamic and peripheral lipid metabolism in a nutritional-dependent fashion
-
Vázquez MJ, Gónzalez CR, Varela L, Lage R, Tovar S, Sangiao-Alvarellos S, Williams LM, Vidal-Puig A, Nogueiras R, López M, Diéguez C. Central resistin regulates hypothalamic and peripheral lipid metabolism in a nutritional-dependent fashion. Endocrinology 2008, 149:4534-4543.
-
(2008)
Endocrinology
, vol.149
, pp. 4534-4543
-
-
Vázquez, M.J.1
Gónzalez, C.R.2
Varela, L.3
Lage, R.4
Tovar, S.5
Sangiao-Alvarellos, S.6
Williams, L.M.7
Vidal-Puig, A.8
Nogueiras, R.9
López, M.10
Diéguez, C.11
-
27
-
-
0014844618
-
The regulation of triglyceride synthesis and fatty acid synthesis in rat epididymal adipose tissue. Effects of altered dietary and hormonal conditions
-
Saggerson ED, Greenbaum AL. The regulation of triglyceride synthesis and fatty acid synthesis in rat epididymal adipose tissue. Effects of altered dietary and hormonal conditions. Biochem J 1970, 119:221-242.
-
(1970)
Biochem J
, vol.119
, pp. 221-242
-
-
Saggerson, E.D.1
Greenbaum, A.L.2
-
28
-
-
0033056271
-
Importance of glucose-6-phosphate dehydrogenase activity in cell death
-
Tian WN, Braunstein LD, Apse K, Pang J, Rose M, Tian X, Stanton RC. Importance of glucose-6-phosphate dehydrogenase activity in cell death. Am J Physiol 1999, 1:C1121-C1131.
-
(1999)
Am J Physiol
, vol.1
-
-
Tian, W.N.1
Braunstein, L.D.2
Apse, K.3
Pang, J.4
Rose, M.5
Tian, X.6
Stanton, R.C.7
-
29
-
-
33746037555
-
Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice
-
Steinberg GR, Watt MJ, Fam BC, Proietto J, Andrikopoulos S, Allen AM, Febbraio MA, Kemp BE. Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice. Endocrinology 2006, 147:3906-3914.
-
(2006)
Endocrinology
, vol.147
, pp. 3906-3914
-
-
Steinberg, G.R.1
Watt, M.J.2
Fam, B.C.3
Proietto, J.4
Andrikopoulos, S.5
Allen, A.M.6
Febbraio, M.A.7
Kemp, B.E.8
-
30
-
-
3242811250
-
Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus
-
McCrimmon RJ, Fan X, Ding Y, Zhu W, Jacob RJ, Sherwin RS. Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus. Diabetes 2004, 53:1953-1958.
-
(2004)
Diabetes
, vol.53
, pp. 1953-1958
-
-
McCrimmon, R.J.1
Fan, X.2
Ding, Y.3
Zhu, W.4
Jacob, R.J.5
Sherwin, R.S.6
-
31
-
-
3142677140
-
Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase
-
Kim MS, Park JY, Namkoong C, Jang PG, Ryu JW, Song HS, Yun JY, Namgoong IS, Ha J, Park IS, Lee IK, Viollet B, Youn JH, Lee HK, Lee KU. Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase. Nat Med 2004, 10:727-733.
-
(2004)
Nat Med
, vol.10
, pp. 727-733
-
-
Kim, M.S.1
Park, J.Y.2
Namkoong, C.3
Jang, P.G.4
Ryu, J.W.5
Song, H.S.6
Yun, J.Y.7
Namgoong, I.S.8
Ha, J.9
Park, I.S.10
Lee, I.K.11
Viollet, B.12
Youn, J.H.13
Lee, H.K.14
Lee, K.U.15
-
32
-
-
34347255023
-
Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake
-
Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T. Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake. Cell Metab 2007, 6:55-68.
-
(2007)
Cell Metab
, vol.6
, pp. 55-68
-
-
Kubota, N.1
Yano, W.2
Kubota, T.3
Yamauchi, T.4
Itoh, S.5
Kumagai, H.6
Kozono, H.7
Takamoto, I.8
Okamoto, S.9
Shiuchi, T.10
Suzuki, R.11
Satoh, H.12
Tsuchida, A.13
Moroi, M.14
Sugi, K.15
Noda, T.16
Ebinuma, H.17
Ueta, Y.18
Kondo, T.19
Araki, E.20
Ezaki, O.21
Nagai, R.22
Tobe, K.23
Terauchi, Y.24
Ueki, K.25
Minokoshi, Y.26
Kadowaki, T.27
more..
-
33
-
-
50449092987
-
Glucocorticoids increase neuropeptide Y and agouti-related peptide gene expression via adenosine monophosphate-activated protein kinase signaling in the arcuate nucleus of rats
-
Shimizu H, Arima H, Watanabe M, Goto M, Banno R, Sato I, Ozaki N, Nagasaki H, Oiso Y. Glucocorticoids increase neuropeptide Y and agouti-related peptide gene expression via adenosine monophosphate-activated protein kinase signaling in the arcuate nucleus of rats. Endocrinology 2008, 149:4544-4553.
-
(2008)
Endocrinology
, vol.149
, pp. 4544-4553
-
-
Shimizu, H.1
Arima, H.2
Watanabe, M.3
Goto, M.4
Banno, R.5
Sato, I.6
Ozaki, N.7
Nagasaki, H.8
Oiso, Y.9
-
34
-
-
56249142279
-
Triiodothyronine (T3) stimulates food intake via enhanced hypothalamic AMP-activated kinase activity
-
Ishii S, Kamegai J, Tamura H, Shimizu T, Sugihara H, Oikawa S. Triiodothyronine (T3) stimulates food intake via enhanced hypothalamic AMP-activated kinase activity. Regul Pept 2008, 3:164-169.
-
(2008)
Regul Pept
, vol.3
, pp. 164-169
-
-
Ishii, S.1
Kamegai, J.2
Tamura, H.3
Shimizu, T.4
Sugihara, H.5
Oikawa, S.6
-
35
-
-
0034733730
-
Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors
-
Loftus TM, Jaworsky DE, Frehywot GL, Townsend CA, Ronnett GV, Lane MD, Kuhajda FP. Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors. Science 2000, 288:2379-2381.
-
(2000)
Science
, vol.288
, pp. 2379-2381
-
-
Loftus, T.M.1
Jaworsky, D.E.2
Frehywot, G.L.3
Townsend, C.A.4
Ronnett, G.V.5
Lane, M.D.6
Kuhajda, F.P.7
-
36
-
-
0242300121
-
Hypothalamic malonyl-CoA as a mediator of feeding behavior
-
Hu Z, Cha SH, Chohnan S, Lane MD. Hypothalamic malonyl-CoA as a mediator of feeding behavior. Proc Natl Acad Sci USA 2003, 100:12624-12629.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 12624-12629
-
-
Hu, Z.1
Cha, S.H.2
Chohnan, S.3
Lane, M.D.4
-
37
-
-
33645731353
-
SREBPs: sterol-regulated transcription factors
-
Espenshade PJ. SREBPs: sterol-regulated transcription factors. J Cell Sci 2006, 6:973-976.
-
(2006)
J Cell Sci
, vol.6
, pp. 973-976
-
-
Espenshade, P.J.1
-
38
-
-
35448976050
-
Down-regulation of AMP-activated protein kinase by calorie restriction in rat liver
-
To K, Yamaza H, Komatsu T, Hayashida T, Hayashi H, Toyama H, Chiba T, Higami Y, Shimokawa I. Down-regulation of AMP-activated protein kinase by calorie restriction in rat liver. Exp Gerontol 2007, 42:1063-1071.
-
(2007)
Exp Gerontol
, vol.42
, pp. 1063-1071
-
-
To, K.1
Yamaza, H.2
Komatsu, T.3
Hayashida, T.4
Hayashi, H.5
Toyama, H.6
Chiba, T.7
Higami, Y.8
Shimokawa, I.9
-
39
-
-
12344335482
-
Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction
-
Al-Regaiey KA, Masternak MM, Bonkowski M, Sun L, Bartke A. Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction. Endocrinology 2005, 146:851-860.
-
(2005)
Endocrinology
, vol.146
, pp. 851-860
-
-
Al-Regaiey, K.A.1
Masternak, M.M.2
Bonkowski, M.3
Sun, L.4
Bartke, A.5
-
40
-
-
34250884797
-
Adipocytokines and the regulation of lipid metabolism in growth hormone transgenic and calorie-restricted mice
-
Wang Z, Masternak MM, Al-Regaiey KA, Bartke A. Adipocytokines and the regulation of lipid metabolism in growth hormone transgenic and calorie-restricted mice. Endocrinology 2007, 148:2845-2853.
-
(2007)
Endocrinology
, vol.148
, pp. 2845-2853
-
-
Wang, Z.1
Masternak, M.M.2
Al-Regaiey, K.A.3
Bartke, A.4
-
41
-
-
12344326642
-
Bovine growth hormone transgenic mice are resistant to diet-induced obesity but develop hyperphagia, dyslipidemia, and diabetes on a high-fat diet
-
Olsson B, Bohlooly YM, Fitzgerald SM, Frick F, Ljungberg A, Ahren B, Tornell J, Bergstrom G, Oscarsson J. Bovine growth hormone transgenic mice are resistant to diet-induced obesity but develop hyperphagia, dyslipidemia, and diabetes on a high-fat diet. Endocrinology 2005, 146:920-930.
-
(2005)
Endocrinology
, vol.146
, pp. 920-930
-
-
Olsson, B.1
Bohlooly, Y.M.2
Fitzgerald, S.M.3
Frick, F.4
Ljungberg, A.5
Ahren, B.6
Tornell, J.7
Bergstrom, G.8
Oscarsson, J.9
-
42
-
-
0031760288
-
Hypothalamic/pituitary-axis of the spontaneous dwarf rat: autofeedback regulation of growth hormone (GH) includes suppression of GH releasing-hormone receptor messenger ribonucleic acid
-
Kamegai J, Unterman TG, Frohman LA, Kineman RD. Hypothalamic/pituitary-axis of the spontaneous dwarf rat: autofeedback regulation of growth hormone (GH) includes suppression of GH releasing-hormone receptor messenger ribonucleic acid. Endocrinology 1998, 139:3554-3560.
-
(1998)
Endocrinology
, vol.139
, pp. 3554-3560
-
-
Kamegai, J.1
Unterman, T.G.2
Frohman, L.A.3
Kineman, R.D.4
-
43
-
-
0029959981
-
Regulation of hypothalamic neuropeptide-Y neurons by growth hormone in the rat
-
Chan YY, Steiner RA, Clifton DK. Regulation of hypothalamic neuropeptide-Y neurons by growth hormone in the rat. Endocrinology 1996, 137:1319-1325.
-
(1996)
Endocrinology
, vol.137
, pp. 1319-1325
-
-
Chan, Y.Y.1
Steiner, R.A.2
Clifton, D.K.3
-
44
-
-
31544465941
-
Molecular disruption of hypothalamic nutrient sensing induces obesity
-
He W, Lam TK, Obici S, Rossetti L. Molecular disruption of hypothalamic nutrient sensing induces obesity. Nat Neurosci 2006, 9:227-233.
-
(2006)
Nat Neurosci
, vol.9
, pp. 227-233
-
-
He, W.1
Lam, T.K.2
Obici, S.3
Rossetti, L.4
-
45
-
-
0033711116
-
The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion
-
Wren AM, Small CJ, Ward HL, Murphy KG, Dakin CL, Taheri S, Kennedy AR, Roberts GH, Morgan DG, Ghatei MA, Bloom SR. The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology 2000, 141:4325-4328.
-
(2000)
Endocrinology
, vol.141
, pp. 4325-4328
-
-
Wren, A.M.1
Small, C.J.2
Ward, H.L.3
Murphy, K.G.4
Dakin, C.L.5
Taheri, S.6
Kennedy, A.R.7
Roberts, G.H.8
Morgan, D.G.9
Ghatei, M.A.10
Bloom, S.R.11
-
46
-
-
33646576512
-
The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis
-
Wolfgang MJ, Kurama T, Dai Y, Suwa A, Asaumi M, Matsumoto S, Cha SH, Shimokawa T, Lane MD. The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis. Proc Natl Acad Sci USA 2006, 103:7282-7287.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7282-7287
-
-
Wolfgang, M.J.1
Kurama, T.2
Dai, Y.3
Suwa, A.4
Asaumi, M.5
Matsumoto, S.6
Cha, S.H.7
Shimokawa, T.8
Lane, M.D.9
-
47
-
-
52949096557
-
Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity
-
Zhang X, Zhang G, Zhang H, Karin M, Bai H, Cai D. Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity. Cell 2008, 135:61-73.
-
(2008)
Cell
, vol.135
, pp. 61-73
-
-
Zhang, X.1
Zhang, G.2
Zhang, H.3
Karin, M.4
Bai, H.5
Cai, D.6
-
48
-
-
57849115277
-
Endoplasmic reticulum stress plays a central role in development of leptin resistance
-
Ozcan L, Ergin AS, Lu A, Chung J, Sarkar S, Nie D, Myers MG, Ozcan U. Endoplasmic reticulum stress plays a central role in development of leptin resistance. Cell Metab 2009, 9:35-51.
-
(2009)
Cell Metab
, vol.9
, pp. 35-51
-
-
Ozcan, L.1
Ergin, A.S.2
Lu, A.3
Chung, J.4
Sarkar, S.5
Nie, D.6
Myers, M.G.7
Ozcan, U.8
-
49
-
-
76049102302
-
Hypothalamic lipotoxicity and the metabolic syndrome
-
Martínez de Morentin PB, Varela L, Ferno J, Nogueiras R, Diéguez C, López M. Hypothalamic lipotoxicity and the metabolic syndrome. Biochim Biophys Acta 2010, 3:350-361.
-
(2010)
Biochim Biophys Acta
, vol.3
, pp. 350-361
-
-
Martínez de Morentin, P.B.1
Varela, L.2
Ferno, J.3
Nogueiras, R.4
Diéguez, C.5
López, M.6
|