The role of hypothalamic malonyl-CoA in energy homeostasis

Journal of Biological Chemistry

Volumn 281, Issue 49, 2006, Pages 37265-37269

  Wolfgang, Michael J ^a   Lane, M Daniel ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; ENZYME INHIBITION; ENZYMES; FATTY ACIDS; GENETIC ENGINEERING; HORMONES;

ENERGY BALANCE; ENERGY SENSING SYSTEM; HYPOTHALAMIC NEURONS; NEURAL SIGNALS;

NEUROLOGY;

ACETYL COENZYME A CARBOXYLASE; ADENYLATE KINASE; FATTY ACID SYNTHASE INHIBITOR; MALONYL COENZYME A;

ANIMAL MODEL; ANTERIOR HYPOTHALAMUS; DRUG MECHANISM; ENERGY BALANCE; ENERGY EXPENDITURE; ENZYME PHOSPHORYLATION; FOOD INTAKE; HOMEOSTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; WEIGHT GAIN;

ACETYL-COA CARBOXYLASE; ADENYLATE KINASE; ANIMALS; EATING; ENERGY METABOLISM; HUMANS; HYPOTHALAMUS; MALONYL COENZYME A; MODELS, BIOLOGICAL; NEURONS; SIGNAL TRANSDUCTION; WEIGHT GAIN;

EID: 33845998567     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.R600016200     Document Type: Short Survey

References (41)

1. Schwartz, M. W., Woods, S. C., Porte, D., Jr., Seeley, R. J., and Baskin, D. G. (2000) Nature 404, 661-671
2. Schwartz, M. W., and Porte, D., Jr. (2005) Science 307, 375-379
3. Friedman, J. M., and Halaas, J. L. (1998) Nature 395, 763-770
4. Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., and Friedman, J. M. (1994) Nature 372, 425-432
5. Vaisse, C., Halaas, J. L., Horvath, C. M., Darnell, J. E., Jr., Stoffel, M., and Friedman, J. M. (1996) Nat. Genet. 14, 95-97
6. Gao, Q., Wolfgang, M. J., Neschen, S., Morino, K., Horvath, T. L., Shulman, G. I., and Fu, X. Y. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 4661-4666
7. Loftus, T. M., Jaworsky, D. E., Frehywot, G. L., Townsend, C. A., Ronnett, G. V., Lane, M. D., and Kuhajda, F. P. (2000) Science 288, 2379-2381
8. Hardie, D. G. (1989) Prog. Lipid Res. 28, 117-146
9. Alam, N., and Saggerson, E. D. (1998) Biochem. J. 334, 233-241 10. Kumar, M. V., Shimokawa, T., Nagy, T. R., and Lane, M. D. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 1921-1925
10. Hu, Z., Cha, S. H., Chohnan, S., and Lane, M. D. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 12624-12629
11. Gao, S., and Lane, M. D. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 5628-5633
12. Aja, S., Bi, S., Knipp, S. B., McFadden, J. M., Ronnett, G. V., Kuhajda, F. P., and Moran, T. H. (2006) Am. J. Physiol. 291, R148-R154
13. Kim, E. K., Miller, I., Landree, L. E., Borisy-Rudin, F. F., Brown, P., Tihan, T., Townsend, C. A., Witters, L. A., Moran, T. H., Kuhajda, F. P., and Ronnett, G. V. (2002) Am. J. Physiol. 283, E867-E879
14. Mills, S. E., Foster, D. W., and McGarry, J. D. (1984) Biochem. J. 219, 601-608
15. Hardie, D. G. (2004) Rev. Endocr. Metab. Disord. 5, 119-125
16. Kahn, B. B., Alquier, T., Carling, D., and Hardie, D. G. (2005) Cell Metab. 1, 15-25
17. Minokoshi, Y., Alquier, T., Furukawa, N., Kim, Y. B., Lee, A., Xue, B., Mu, J., Foufelle, F., Ferre, P., Birnbaum, M. J., Stuck, B. J., and Kahn, B. B. (2004) Nature 428, 569-574
18. Andersson, U., Filipsson, K., Abbott, C. R., Woods, A., Smith, K., Bloom, S. R., Carling, D., and Small, C. J. (2004) J. Biol. Chem. 279, 12005-12008
19. Kim, E. K., Miller, I., Aja, S., Landree, L. E., Pinn, M., McFadden, J., Kuhajda, F. P., Moran, T. H., and Ronnett, G. V. (2004) J. Biol. Chem. 279, 19970-19976
20. Hu, Z., Dai, Y., Prentki, M., Chohnan, S., and Lane, M. D. (2005) J. Biol. Chem. 280, 39681-39683
21. An, J., Muoio, D. M., Shiota, M., Fujimoto, Y., Cline, G. W., Shulman, G. I., Koves, T. R., Stevens, R., Millington, D., and Newgard, C. B. (2004) Nat. Med. 10, 268-274
22. He, W., Lam, T. K., Obici, S., and Rossetti, L. (2006) Nat. Neurosci. 9, 227-233
23. Cha, S. H., Hu, Z., Chohnan, S., and Lane, M. D. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 14557-14562
24. Cha, S. H., Rodgers, J. T., Puigserver, P., Chohnan, S., and Lane, M. D. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 15410-15415
25. Thupari, J. N., Landree, L. E., Ronnett, G. V., and Kuhajda, F. P. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 9498-9502
26. Cha, S. H., Hu, Z., and Lane, M. D. (2004) Biochem. Biophys. Res. Commun. 317, 301-308
27. Kuhajda, F. P., Landree, L. E., and Ronnett, G. V. (2005) Trends Pharmacol. Sci. 26, 541-544
28. de Wit, M. C., de Coo, I. F., Verbeek, E., Schot, R., Schoonderwoerd, G. C., Duran, M., de Klerk, J. B., Huijmans, J. G., Lequin, M. H., Verheijen, F. W., and Mancini, G. M. (2006) Mol. Genet. Metab. 87, 102-106
29. Ronnett, G. V., Kim, E. K., Landree, L. E., and Tu, Y. (2005) Physiol. Behav. 85, 25-35
30. McGarry, J. D., Mannaerts, G. P., and Foster, D. W. (1977) J. Clin. Invest. 60, 265-270
31. McGarry, J. D., Leatherman, G. F., and Foster, D. W. (1978) J. Biol. Chem. 253, 4128-4136
32. McGarry, J. D., and Foster, D. W. (1980) Annu. Rev. Biochem. 49, 395-420
33. McGarry, J. D. (1995) Biochem. Soc. Trans. 23, 481-485
34. McGarry, J. D. (1995) Biochem. Soc. Trans. 23, 321-324
35. Obici, S., Feng, Z., Morgan, K., Stein, D., Karkanias, G., and Rossetti, L. (2002) Diabetes 51, 271-275
36. Lam, T. K., Schwartz, G. J., and Rossetti, L. (2005) Nat. Neurosci. 8, 579-584
37. Obici, S., Feng, Z., Arduini, A., Conti, R., and Rossetti, L. (2003) Nat. Med. 9, 756-761
38. Price, N., van der Leij, F., Jackson, V., Corstorphine, C., Thomson, R., Sorensen, A., and Zammit, V. (2002) Genomics 80, 433-442
39. Wolfgang, M. J., Kurama, T., Dai, Y., Suwa, A., Asaumi, M., Matsumoto, S., Cha, S. H., Shimokawa, T., and Lane, M. D. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 7282-7287
40. Yang, N., Kays, J. S., Skillman, T. R., Burris, L., Seng, T. W., and Hammond, C. (2005) J. Pharmacol. Exp. Ther. 312, 127-133
41. Bentebibel, A., Sebastian, D., Herrero, L., Lopez-Vinas, E., Serra, D., Asins, G., Gomez-Puertas, P., and Hegardt, F. G. (2006) Biochemistry 45, 4339-435