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Volumn 71, Issue 7, 2010, Pages 682-691

Disparity in circulating peripheral blood dendritic cell subsets and cytokine profile of pulmonary tuberculosis patients compared with healthy family contacts

Author keywords

IFN ; IL 12; Myeloid dendritic cells; Plasmacytoid DC; Pulmonary tuberculosis

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 77953916581     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2010.03.010     Document Type: Article
Times cited : (9)

References (50)
  • 1
    • 0028863847 scopus 로고
    • Functions of T-cell subsets and cytokines in mycobacterial infections
    • Munk M.E., Emoto M. Functions of T-cell subsets and cytokines in mycobacterial infections. Eur Respir J Suppl 1995, 20:668s-675s.
    • (1995) Eur Respir J Suppl , vol.20
    • Munk, M.E.1    Emoto, M.2
  • 2
    • 34548133569 scopus 로고    scopus 로고
    • Dendritic cells: A conductor of T cell differentiation
    • Kadowaki N. Dendritic cells: A conductor of T cell differentiation. Allergol Int 2007, 56:193-199.
    • (2007) Allergol Int , vol.56 , pp. 193-199
    • Kadowaki, N.1
  • 4
    • 0030781916 scopus 로고    scopus 로고
    • Dendritic cells: Unique leukocyte populations which control the primary immune response
    • Hart D.N. Dendritic cells: Unique leukocyte populations which control the primary immune response. Blood 1997, 90:3245-3287.
    • (1997) Blood , vol.90 , pp. 3245-3287
    • Hart, D.N.1
  • 7
    • 9344263448 scopus 로고    scopus 로고
    • Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs
    • Ferlazzo G., Pack M., Thomas D., Paludan C., Schmid D., Strowig T., et al. Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs. Proc Natl Acad Sci U S A 2004, 101:16606-16611.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 16606-16611
    • Ferlazzo, G.1    Pack, M.2    Thomas, D.3    Paludan, C.4    Schmid, D.5    Strowig, T.6
  • 8
    • 34948911347 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients
    • Decalf J., Fernandes S., Longman R., Ahloulay M., Audat F., Lefrerre F., et al. Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients. J Exp Med 2007, 204:2423-2437.
    • (2007) J Exp Med , vol.204 , pp. 2423-2437
    • Decalf, J.1    Fernandes, S.2    Longman, R.3    Ahloulay, M.4    Audat, F.5    Lefrerre, F.6
  • 9
    • 58149292271 scopus 로고    scopus 로고
    • Infection of myeloid dendritic cells with Listeria monocytogenes leads to the suppression of T cell function by multiple inhibitory mechanisms
    • Popov A., Driesen J., Abdullah Z., Wickenhauser C., Beyer M., Debey-Pascher S., et al. Infection of myeloid dendritic cells with Listeria monocytogenes leads to the suppression of T cell function by multiple inhibitory mechanisms. J Immunol 2008, 181:4976-4988.
    • (2008) J Immunol , vol.181 , pp. 4976-4988
    • Popov, A.1    Driesen, J.2    Abdullah, Z.3    Wickenhauser, C.4    Beyer, M.5    Debey-Pascher, S.6
  • 10
    • 22144441229 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells-virus experts of innate immunity
    • Barchet W., Cella M., Colonna M. Plasmacytoid dendritic cells-virus experts of innate immunity. Semin Immunol 2005, 17:253-261.
    • (2005) Semin Immunol , vol.17 , pp. 253-261
    • Barchet, W.1    Cella, M.2    Colonna, M.3
  • 11
    • 0041429619 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6
    • Jego G., Palucka A.K., Blanck J.P., Chalouni C., Pascual V., Banchereau J. Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6. Immunity 2003, 19:225-234.
    • (2003) Immunity , vol.19 , pp. 225-234
    • Jego, G.1    Palucka, A.K.2    Blanck, J.P.3    Chalouni, C.4    Pascual, V.5    Banchereau, J.6
  • 12
    • 33846162277 scopus 로고    scopus 로고
    • Quantitative and functional differences between peripheral blood myeloid dendritic cells from patients with pleural and parenchymal lung tuberculosis
    • Mendelson M., Hanekom W.A., Ntutela S., Vogt M., Steyn L., Maartens G., Kaplan G. Quantitative and functional differences between peripheral blood myeloid dendritic cells from patients with pleural and parenchymal lung tuberculosis. Clin Vaccine Immunol 2006, 13:1299-1306.
    • (2006) Clin Vaccine Immunol , vol.13 , pp. 1299-1306
    • Mendelson, M.1    Hanekom, W.A.2    Ntutela, S.3    Vogt, M.4    Steyn, L.5    Maartens, G.6    Kaplan, G.7
  • 13
    • 0036909066 scopus 로고    scopus 로고
    • Dendritic cells are decreased in blood and accumulated in granuloma in tuberculosis
    • Uehira K., Amakawa R., Ito T., Tajima K., Naitoh S., Ozaki Y., et al. Dendritic cells are decreased in blood and accumulated in granuloma in tuberculosis. Clin Immunol 2002, 105:296-303.
    • (2002) Clin Immunol , vol.105 , pp. 296-303
    • Uehira, K.1    Amakawa, R.2    Ito, T.3    Tajima, K.4    Naitoh, S.5    Ozaki, Y.6
  • 14
    • 33644864548 scopus 로고    scopus 로고
    • Circulating dendritic cells and interferon-alpha production in patients with tuberculosis: Correlation with clinical outcome and treatment response
    • Lichtner M., Rossi R., Mengoni F., Vignoli S., Colacchia B., Massetti A.P., et al. Circulating dendritic cells and interferon-alpha production in patients with tuberculosis: Correlation with clinical outcome and treatment response. Clin Exp Immunol 2006, 143:329-337.
    • (2006) Clin Exp Immunol , vol.143 , pp. 329-337
    • Lichtner, M.1    Rossi, R.2    Mengoni, F.3    Vignoli, S.4    Colacchia, B.5    Massetti, A.P.6
  • 15
    • 0037108623 scopus 로고    scopus 로고
    • Alteration of balance between myeloid dendritic cells and plasmacytoid dendritic cells in peripheral blood of patients with asthma
    • Matsuda H., Suda T., Hashizume H., Yokomura K., Asada K., Suzuki K., et al. Alteration of balance between myeloid dendritic cells and plasmacytoid dendritic cells in peripheral blood of patients with asthma. Am J Respir Crit Care Med 2002, 166:1050-1054.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 1050-1054
    • Matsuda, H.1    Suda, T.2    Hashizume, H.3    Yokomura, K.4    Asada, K.5    Suzuki, K.6
  • 16
    • 0242410830 scopus 로고    scopus 로고
    • A blunted blood plasmacytoid dendritic cell response to an acute systemic viral infection is associated with increased disease severity
    • Pichyangkul S., Endy T.P., Kalayanarooj S., Nisalak A., Yongvanitchit K., Green S., et al. A blunted blood plasmacytoid dendritic cell response to an acute systemic viral infection is associated with increased disease severity. J Immunol 2003, 171:5571-5578.
    • (2003) J Immunol , vol.171 , pp. 5571-5578
    • Pichyangkul, S.1    Endy, T.P.2    Kalayanarooj, S.3    Nisalak, A.4    Yongvanitchit, K.5    Green, S.6
  • 18
    • 0036569399 scopus 로고    scopus 로고
    • Persistent decreases in blood plasmacytoid dendritic cell number and function despite effective highly active antiretroviral therapy and increased blood myeloid dendritic cells in HIV-infected individuals
    • Chehimi J., Campbell D.E., Azzoni L., Bacheller D., Papasavvas E., Jerandi G., et al. Persistent decreases in blood plasmacytoid dendritic cell number and function despite effective highly active antiretroviral therapy and increased blood myeloid dendritic cells in HIV-infected individuals. J Immunol 2002, 168:4796-4801.
    • (2002) J Immunol , vol.168 , pp. 4796-4801
    • Chehimi, J.1    Campbell, D.E.2    Azzoni, L.3    Bacheller, D.4    Papasavvas, E.5    Jerandi, G.6
  • 19
    • 33845496052 scopus 로고    scopus 로고
    • The frequency of BDCA3-positive dendritic cells is increased in the peripheral circulation of Kenyan children with severe malaria
    • Urban B.C., Cordery D., Shafi M.J., Bull P.C., Newbold C.I., Williams T.N., Marsh K. The frequency of BDCA3-positive dendritic cells is increased in the peripheral circulation of Kenyan children with severe malaria. Infect Immun 2006, 74:6700-6706.
    • (2006) Infect Immun , vol.74 , pp. 6700-6706
    • Urban, B.C.1    Cordery, D.2    Shafi, M.J.3    Bull, P.C.4    Newbold, C.I.5    Williams, T.N.6    Marsh, K.7
  • 20
    • 4744366784 scopus 로고    scopus 로고
    • Dendritic cells derived from BCG-infected precursors induce Th2-like immune response
    • Martino A., Sacchi A., Sanarico N., Spadaro F., Ramoni C., Ciaramella A., et al. Dendritic cells derived from BCG-infected precursors induce Th2-like immune response. J Leukoc Biol 2004, 76:827-834.
    • (2004) J Leukoc Biol , vol.76 , pp. 827-834
    • Martino, A.1    Sacchi, A.2    Sanarico, N.3    Spadaro, F.4    Ramoni, C.5    Ciaramella, A.6
  • 21
    • 0036720238 scopus 로고    scopus 로고
    • Mycobacterium leprae infection in monocyte-derived dendritic cells and its influence on antigen-presenting function
    • Hashimoto K., Maeda Y., Kimura H., Suzuki K., Masuda A., Matsuoka M., Makino M. Mycobacterium leprae infection in monocyte-derived dendritic cells and its influence on antigen-presenting function. Infect Immun 2002, 70:5167-5176.
    • (2002) Infect Immun , vol.70 , pp. 5167-5176
    • Hashimoto, K.1    Maeda, Y.2    Kimura, H.3    Suzuki, K.4    Masuda, A.5    Matsuoka, M.6    Makino, M.7
  • 22
    • 0031570821 scopus 로고    scopus 로고
    • Activation of human dendritic cells following infection with Mycobacterium tuberculosis
    • Henderson R.A., Watkins S.C., Flynn J.L. Activation of human dendritic cells following infection with Mycobacterium tuberculosis. J Immunol 1997, 159:635-643.
    • (1997) J Immunol , vol.159 , pp. 635-643
    • Henderson, R.A.1    Watkins, S.C.2    Flynn, J.L.3
  • 23
    • 39149106466 scopus 로고    scopus 로고
    • Modulation of pulmonary dendritic cell function during mycobacterial infection
    • Anis M.M., Fulton S.A., Reba S.M., Liu Y., Harding C.V., Boom W.H. Modulation of pulmonary dendritic cell function during mycobacterial infection. Infect Immun 2008, 76:671-677.
    • (2008) Infect Immun , vol.76 , pp. 671-677
    • Anis, M.M.1    Fulton, S.A.2    Reba, S.M.3    Liu, Y.4    Harding, C.V.5    Boom, W.H.6
  • 24
    • 34848910546 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis infects dendritic cells with high frequency and impairs their function in vivo
    • Wolf A.J., Linas B., Trevejo-Nunez G.J., Kincaid E., Tamura T., Takatsu K., Ernst J.D. Mycobacterium tuberculosis infects dendritic cells with high frequency and impairs their function in vivo. J Immunol 2007, 179:2509-2519.
    • (2007) J Immunol , vol.179 , pp. 2509-2519
    • Wolf, A.J.1    Linas, B.2    Trevejo-Nunez, G.J.3    Kincaid, E.4    Tamura, T.5    Takatsu, K.6    Ernst, J.D.7
  • 25
    • 0037114165 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis antigens induce the differentiation of dendritic cells from bone marrow
    • Latchumanan V.K., Singh B., Sharma P., Natarajan K. Mycobacterium tuberculosis antigens induce the differentiation of dendritic cells from bone marrow. J Immunol 2002, 169:6856-6864.
    • (2002) J Immunol , vol.169 , pp. 6856-6864
    • Latchumanan, V.K.1    Singh, B.2    Sharma, P.3    Natarajan, K.4
  • 26
    • 9444280924 scopus 로고    scopus 로고
    • Reduced numbers and impaired ability of myeloid and plasmacytoid dendritic cells to polarize T helper cells in chronic hepatitis C virus infection
    • Kanto T., Inoue M., Miyatake H., Sato A., Sakakibara M., Yakushijin T., et al. Reduced numbers and impaired ability of myeloid and plasmacytoid dendritic cells to polarize T helper cells in chronic hepatitis C virus infection. J Infect Dis 2004, 190:1919-1926.
    • (2004) J Infect Dis , vol.190 , pp. 1919-1926
    • Kanto, T.1    Inoue, M.2    Miyatake, H.3    Sato, A.4    Sakakibara, M.5    Yakushijin, T.6
  • 27
    • 0036797824 scopus 로고    scopus 로고
    • Cruzi down-regulates lipopolysaccharide-induced MHC class I on human dendritic cells and impairs antigen presentation to specific CD8(+) T lymphocytes
    • Van Overtvelt L., Andrieu M., Verhasselt V., Connan F., Choppin J., Vercruysse V., et al. Cruzi down-regulates lipopolysaccharide-induced MHC class I on human dendritic cells and impairs antigen presentation to specific CD8(+) T lymphocytes. Int Immunol 2002, 14:1135-1144.
    • (2002) Int Immunol , vol.14 , pp. 1135-1144
    • Van Overtvelt, L.1    Andrieu, M.2    Verhasselt, V.3    Connan, F.4    Choppin, J.5    Vercruysse, V.6
  • 28
  • 31
    • 0037236693 scopus 로고    scopus 로고
    • Serum cytokine concentrations do not parallel Mycobacterium tuberculosis-induced cytokine production in patients with tuberculosis
    • Vankayalapati R., Wizel B., Weis S.E., Klucar P., Shams H., Samten B., Barnes P.F. Serum cytokine concentrations do not parallel Mycobacterium tuberculosis-induced cytokine production in patients with tuberculosis. Clin Infect Dis 2003, 36:24-28.
    • (2003) Clin Infect Dis , vol.36 , pp. 24-28
    • Vankayalapati, R.1    Wizel, B.2    Weis, S.E.3    Klucar, P.4    Shams, H.5    Samten, B.6    Barnes, P.F.7
  • 32
    • 0032706006 scopus 로고    scopus 로고
    • Dichotomy of cytokine profiles in patients and high-risk healthy subjects exposed to tuberculosis
    • Bhattacharyya S., Singla R., Dey A.B., Prasad H.K. Dichotomy of cytokine profiles in patients and high-risk healthy subjects exposed to tuberculosis. Infect Immun 1999, 67:5597-5603.
    • (1999) Infect Immun , vol.67 , pp. 5597-5603
    • Bhattacharyya, S.1    Singla, R.2    Dey, A.B.3    Prasad, H.K.4
  • 33
    • 27644509659 scopus 로고    scopus 로고
    • Changes in serum cytokine levels in active tuberculosis with treatment
    • Deveci F., Akbulut H.H., Turgut T., Muz M.H. Changes in serum cytokine levels in active tuberculosis with treatment. Mediat Inflamm 2005 2005, 5:256-262.
    • (2005) Mediat Inflamm 2005 , vol.5 , pp. 256-262
    • Deveci, F.1    Akbulut, H.H.2    Turgut, T.3    Muz, M.H.4
  • 35
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • Oppmann B., Lesley R., Blom B., Timans J.C., Xu Y., Hunte B., et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 2000, 13:715-725.
    • (2000) Immunity , vol.13 , pp. 715-725
    • Oppmann, B.1    Lesley, R.2    Blom, B.3    Timans, J.C.4    Xu, Y.5    Hunte, B.6
  • 36
    • 18444385868 scopus 로고    scopus 로고
    • IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells
    • Pflanz S., Timans J.C., Cheung J., Rosales R., Kanzler H., Gilbert J., et al. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells. Immunity 2002, 16:779-790.
    • (2002) Immunity , vol.16 , pp. 779-790
    • Pflanz, S.1    Timans, J.C.2    Cheung, J.3    Rosales, R.4    Kanzler, H.5    Gilbert, J.6
  • 37
    • 1642493660 scopus 로고    scopus 로고
    • Monocyte cytokine secretion in patients with pulmonary tuberculosis differs from that of healthy infected subjects and correlates with clinical manifestations
    • Pereira C.B., Palaci M., Leite O.H., Duarte A.J., Benard G. Monocyte cytokine secretion in patients with pulmonary tuberculosis differs from that of healthy infected subjects and correlates with clinical manifestations. Microbes Infect 2004, 6:25-33.
    • (2004) Microbes Infect , vol.6 , pp. 25-33
    • Pereira, C.B.1    Palaci, M.2    Leite, O.H.3    Duarte, A.J.4    Benard, G.5
  • 38
    • 23244458100 scopus 로고    scopus 로고
    • IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available
    • Khader S.A., Pearl J.E., Sakamoto K., Gilmartin L., Bell G.K., Jelley-Gibbs D.M., et al. IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available. J Immunol 2005, 175:788-795.
    • (2005) J Immunol , vol.175 , pp. 788-795
    • Khader, S.A.1    Pearl, J.E.2    Sakamoto, K.3    Gilmartin, L.4    Bell, G.K.5    Jelley-Gibbs, D.M.6
  • 39
    • 34248395113 scopus 로고    scopus 로고
    • Modulation of gamma interferon receptor 1 by Mycobacterium tuberculosis: A potential immune response evasive mechanism
    • Singhal A., Jaiswal A., Arora V.K., Prasad H.K. Modulation of gamma interferon receptor 1 by Mycobacterium tuberculosis: A potential immune response evasive mechanism. Infect Immun 2007, 75:2500-2510.
    • (2007) Infect Immun , vol.75 , pp. 2500-2510
    • Singhal, A.1    Jaiswal, A.2    Arora, V.K.3    Prasad, H.K.4
  • 40
    • 2442544416 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis inhibits macrophage responses to IFN-gamma through myeloid differentiation factor 88-dependent and -independent mechanisms
    • Fortune S.M., Solache A., Jaeger A., Hill P.J., Belisle J.T., Bloom B.R., et al. Mycobacterium tuberculosis inhibits macrophage responses to IFN-gamma through myeloid differentiation factor 88-dependent and -independent mechanisms. J Immunol 2004, 172:6272-6280.
    • (2004) J Immunol , vol.172 , pp. 6272-6280
    • Fortune, S.M.1    Solache, A.2    Jaeger, A.3    Hill, P.J.4    Belisle, J.T.5    Bloom, B.R.6
  • 41
    • 0027360333 scopus 로고
    • An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection
    • Flynn J.L., Chan J., Triebold K.J., Dalton D.K., Stewart T.A., Bloom B.R. An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. J Exp Med 1993, 178:2249-2254.
    • (1993) J Exp Med , vol.178 , pp. 2249-2254
    • Flynn, J.L.1    Chan, J.2    Triebold, K.J.3    Dalton, D.K.4    Stewart, T.A.5    Bloom, B.R.6
  • 42
    • 0142211129 scopus 로고    scopus 로고
    • + T cells mediate IFN-gamma-independent control of Mycobacterium tuberculosis infection both in vitro and in vivo
    • + T cells mediate IFN-gamma-independent control of Mycobacterium tuberculosis infection both in vitro and in vivo. J Immunol 2003, 171:4689-4699.
    • (2003) J Immunol , vol.171 , pp. 4689-4699
    • Cowley, S.C.1    Elkins, K.L.2
  • 43
    • 12144287655 scopus 로고    scopus 로고
    • Interferon-gamma production and host protective response against Mycobacterium tuberculosis in mice lacking both IL-12p40 and IL-18
    • Kawakami K., Kinjo Y., Uezu K., Miyagi K., Kinjo T., Yara S., et al. Interferon-gamma production and host protective response against Mycobacterium tuberculosis in mice lacking both IL-12p40 and IL-18. Microbes Infect 2004, 6:339-349.
    • (2004) Microbes Infect , vol.6 , pp. 339-349
    • Kawakami, K.1    Kinjo, Y.2    Uezu, K.3    Miyagi, K.4    Kinjo, T.5    Yara, S.6
  • 44
    • 0030297825 scopus 로고    scopus 로고
    • Toxoplasma gondii: Evidence for interleukin-12-dependent and-independent pathways of interferon-gamma production induced by an attenuated parasite strain
    • Scharton-Kersten T., Caspar P., Sher A., Denkers E.Y. Toxoplasma gondii: Evidence for interleukin-12-dependent and-independent pathways of interferon-gamma production induced by an attenuated parasite strain. Exp Parasitol 1996, 84:102-114.
    • (1996) Exp Parasitol , vol.84 , pp. 102-114
    • Scharton-Kersten, T.1    Caspar, P.2    Sher, A.3    Denkers, E.Y.4
  • 45
    • 2142656355 scopus 로고    scopus 로고
    • Production of interferon gamma in respiratory syncytial virus infection of humans is not associated with interleukins 12 and 18
    • Garofalo R.P., Hintz K.H., Hill V., Ogra P.L., Welliver R.C.Sen Production of interferon gamma in respiratory syncytial virus infection of humans is not associated with interleukins 12 and 18. J Med Virol 2004, 73:289-294.
    • (2004) J Med Virol , vol.73 , pp. 289-294
    • Garofalo, R.P.1    Hintz, K.H.2    Hill, V.3    Ogra, P.L.4    Welliver, R.5
  • 46
    • 0034254583 scopus 로고    scopus 로고
    • Human dendritic cells discriminate between viable and killed Toxoplasma gondii tachyzoites: Dendritic cell activation after infection with viable parasites results in CD28 and CD40 ligand signaling that controls IL-12-dependent and -independent T cell production of IFN-gamma
    • Subauste C.S., Wessendarp M. Human dendritic cells discriminate between viable and killed Toxoplasma gondii tachyzoites: Dendritic cell activation after infection with viable parasites results in CD28 and CD40 ligand signaling that controls IL-12-dependent and -independent T cell production of IFN-gamma. J Immunol 2000, 165:1498-1505.
    • (2000) J Immunol , vol.165 , pp. 1498-1505
    • Subauste, C.S.1    Wessendarp, M.2
  • 47
    • 0034019455 scopus 로고    scopus 로고
    • Depressed CD40 ligand expression contributes to reduced gamma interferon production in human tuberculosis
    • Samten B., Thomas E.K., Gong J., Barnes P.F. Depressed CD40 ligand expression contributes to reduced gamma interferon production in human tuberculosis. Infect Immun 2000, 68:3002-3006.
    • (2000) Infect Immun , vol.68 , pp. 3002-3006
    • Samten, B.1    Thomas, E.K.2    Gong, J.3    Barnes, P.F.4
  • 48
    • 0035826721 scopus 로고    scopus 로고
    • Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-alpha /beta
    • Manca C., Tsenova L., Bergtold A., Freeman S., Tovey M., Musser J.M., et al. Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-alpha /beta. Proc Natl Acad Sci U S A 2001, 98:5752-5757.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5752-5757
    • Manca, C.1    Tsenova, L.2    Bergtold, A.3    Freeman, S.4    Tovey, M.5    Musser, J.M.6


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