Mycobacterium leprae infection in monocyte-derived dendritic cells and its influence on antigen-presenting function

Infection and Immunity

Volumn 70, Issue 9, 2002, Pages 5167-5176

  Hashimoto, Ken ^a   Maeda, Yumi ^a   Kimura, Hiroaki ^a   Suzuki, Koichi ^a   Masuda, Akihiro ^a   Matsuoka, Masanori ^a   Makino, Masahiko ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; BCG VACCINE; CD40 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; HLA ANTIGEN; HLA DR ANTIGEN; MEMBRANE ANTIGEN; MONOCLONAL ANTIBODY; PHENOLIC GLYCOLIPID I;

ANTIGEN PRESENTING CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; HOST RESISTANCE; HUMAN; HUMAN CELL; LEPROSY; MONOCYTE; MYCOBACTERIUM AVIUM; MYCOBACTERIUM BOVIS; MYCOBACTERIUM LEPRAE; PHAGOCYTOSIS; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; ANTIGEN PRESENTATION; ANTIGENS, BACTERIAL; ANTIGENS, CD; ANTIGENS, CD86; DENDRITIC CELLS; GLYCOLIPIDS; HLA ANTIGENS; HUMANS; IMMUNOGLOBULINS; INTERFERON TYPE II; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MONOCYTES; MYCOBACTERIUM LEPRAE; T-LYMPHOCYTES;

EID: 0036720238     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.70.9.5167-5176.2002     Document Type: Article

References (53)

1. Patterns of cytokine production by Mycobacterium tuberculosis-reactive human T-cell clones
2. + cells by Mycobacterium tuberculosis via an alternate class I MHC antigen-processing pathway
3. Interleukin 10 inhibits T cell alloreaction induced by human dendritic cells
4. Protection against aerosol Mycobacterium tuberculosis infection using Mycobacterium bovis Bacillus Calmette Guerin-infected dendritic cells
5. Stimulation of dendritic cells via CD40 enhances immune responses to Mycobacterium tuberculosis infection
6. New, simple flow cytometry technique to discriminate between internalized and membrane-bound particles in phagocytosis
7. Dendritic cells infected with Mycobacterium bovis bacillus Calmette Guerin activate CD8(+) T cells with specificity for a novel mycobacterial epitope
8. An essential role for interferon-γ in resistance to Mycobacterium tuberculosis infection
9. IL-10 converts human dendritic cells into macrophage-like cells with increased antibacterial activity against virulent Mycobacterium tuberculosis
10. Production of transforming growth factor-beta 1 (TGF-β1) by blood monocytes from patients with different clinical forms of leprosy
11. The use of fluorescence quenching in flow cytofluorometry to measure the attachment and ingestion phases in phagocytosis in peripheral blood without prior cell separation
12. Activation of human dendritic cells following infection with Mycobacterium tuberculosis
13. Attenuation of HLA-DR expression by mononuclear phagocytes infected with Mycobacterium tuberculosis is related to intracellular sequestration of immature class II heterodimers
14. Dendritic cells induce CD4+ and CD8+ T-cell responses to Mycobacterium bovis and M. avium antigens in Bacille Calmette Guerin vaccinated and nonvaccinated cattle
15. Dendritic cell progenitors phagocytose particulates, including bacillus Calmette-Guerin organisms, and sensitize mice to mycobacterial antigens in vivo
16. Nerve damage in leprosy
17. Peripheral nerve pathology
18. Effect of chemotherapy on viability of Mycobacterium leprae as determined by ATP content, morphological index and FDA-EB fluorescent staining
19. Enhanced antigen-presenting activity and tumour necrosis factor-alpha-independent activation of dendritic cells following treatment with Mycobacterium bovis bacillus Calmette-Guerin
20. Immune response to Mycobacterium bovis bacilli Calmette-Guerin infection in major histocompatibility complex class I- and II-deficient knock-out mice: Contribution of CD4 and CD8 T cells to acquired resistance
21. + T cells reactive with Mycobacterium tuberculosis-infected antigen presenting cells
22. Mycobacterium tuberculosis-reactive CD8+ T lymphocytes: The relative contribution of classical versus nonclassical HLA restriction
23. Establishment of a cryopreservation method of human peripheral blood mononuclear cells for efficient production of dendritic cells
24. The role of HTLV-I-infected dendritic cells in the development of HTLVI-associated myelopathy/tropical spastic paraparesis
25. Production of functionally deficient dendritic cells from HTLV-I-infected monocytes: Implication for the dendritic cell defect in adult T cell leukemia
26. Lymphocyte suppression in leprosy induced by unique M. leprae glycolipid
27. Human T cell proliferative responses to particulate microbial antigens are supported by populations enriched in dendritic cells
28. A mutation in the interferon-γ-receptor gene and susceptibility to mycobacterial infection
29. Suppression of Con A response of mouse lymphocytes with unique M. leprae glycolipid
30. Toll-like receptor 2-dependent inhibition of macrophage class II MHC expression and antigen processing by 19-kDa lipoprotein of Mycobacterium tuberculosis
31. Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium
32. Cytokine secretion by CD4 T lymphocytes acquired in response to Mycobacterium tuberculosis infection
33. Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lyric, granule proteins
34. Phenolic glycolopid-I of Mycobacterium leprae induces general suppression of in vitro concanavalin a responses unrelated to leprosy type
35. Human T cell responses induced by vaccination with Mycobacterium bovis BCG
36. Classification of leprosy according to immunity: A five-group system
37. Dendritic cell loss from non-lymphoid tissues after systemic administration of lipopolysaccharide, tumor necrosis factor, and interleukin 1
38. Hereditary characteristic that varies among isolates of Mycobacterium leprae
39. CD1 expression by dendritic cells in human leprosy lesions: Correlation with effective host immunity
40. + T cells in the CD1-restricted repertoire: Derivation of mycobacteria-reactive T cells from leprosy lesions
41. + CTL specific for the mycobacterial major secreted antigen 85A
42. We need to know what is happening to the incidence of leprosy
43. An antimicrobial activity of cytolytic T cells mediated by granulysin
44. Importance of the neural predilection of Mycobacterium leprae in leprosy
45. + cytotoxic T cells and relative resistance of alveolar macrophages to lysis
46. Mycobacterium tuberculosis-activated dendritic cells induce protective immunity in mice
47. CTL-mediated killing of intracellular Mycobacterium tuberculosis is independent of target cell nuclear apoptosis
48. Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guerin: Involvement of toll-like receptors
49. Interaction of Mycobacterium avium-containing phagosomes with the antigen presentation pathway
50. Accessory cell function of dendritic cells from lymph nodes containing Mycobacterium leprae induced granulomas
51. Leprosy - Global situation
52. A role for CD40-CD40 ligand interactions in the generation of type 1 cytokine responses in human leprosy