HIV-1 Tat-peptide inhibits protein kinase C and protein kinase A through substrate competition

European Journal of Pharmaceutical Sciences

Volumn 40, Issue 5, 2010, Pages 404-411

  Ekokoski, Elina ^a   Aitio, Olli ^b   Törnquist, Kid ^c,d   Yli Kauhaluoma, Jari ^a   Tuominen, Raimo K ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c ÅBO AKADEMI UNIVERSITY   (Finland)

^d MINERVA FOUNDATION INSTITUTE FOR MEDICAL RESEARCH   (Finland)

Author keywords

Arginine rich peptide; Basophilic kinase; Inhibitor; Protein kinase A; Protein kinase C; Substrate peptide; Tat peptide

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE; PROTEIN KINASE C; SPHINGOSYLPHOSPHORYLCHOLINE; TRANSACTIVATOR PROTEIN; CALCIUM; PEPTIDE; PEPTIDE FRAGMENT; TAT PEPTIDE (48-60), HUMAN IMMUNODEFICIENCY VIRUS 1;

ARTICLE; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE COMPLEX; HELA CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; THYROID CELL; ANTAGONISTS AND INHIBITORS; HELA CELL LINE; KINETICS; METABOLISM; PHOSPHORYLATION; THYROID GLAND; TUMOR CELL LINE;

ADENOSINE TRIPHOSPHATE; CALCIUM; CELL LINE, TUMOR; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HELA CELLS; HUMANS; KINETICS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PEPTIDE FRAGMENTS; PEPTIDES; PHOSPHORYLATION; PROTEIN KINASE C; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; THYROID GLAND;

EID: 77953916465     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2010.04.013     Document Type: Article

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