-
1
-
-
0029918548
-
Current status of CF gene therapy
-
Boucher R. Current status of CF gene therapy. Trends Genet. 1999; 12: 81-4.
-
(1999)
Trends Genet
, vol.12
, pp. 81-84
-
-
Boucher, R.1
-
2
-
-
13844276394
-
The use of retroviral vectors for gene therapy-what are the risks? A review of retroviral pathogenesis and its relevance to retroviral vector-mediated gene delivery
-
Anson DS. The use of retroviral vectors for gene therapy-what are the risks? A review of retroviral pathogenesis and its relevance to retroviral vector-mediated gene delivery. Genet Vaccines Ther. 2004; 2: 9.
-
(2004)
Genet Vaccines Ther
, vol.2
, pp. 9
-
-
Anson, D.S.1
-
3
-
-
33745241652
-
Therapeutic level of functional human alpha 1 antitrypsin (hAAT) secreted from murine muscle transduced by adeno-associated virus (rAAV1) vector
-
Lu Y, Choi YK, Campbell-Thompson M, et al. Therapeutic level of functional human alpha 1 antitrypsin (hAAT) secreted from murine muscle transduced by adeno-associated virus (rAAV1) vector. J Gene Med. 2006; 8: 730-5.
-
(2006)
J Gene Med
, vol.8
, pp. 730-735
-
-
Lu, Y.1
Choi, Y.K.2
Campbell-Thompson, M.3
-
4
-
-
4444370799
-
Gene therapy clinical trials worldwide 1989-2004-an overview
-
Edelstein ML, Abedi MR, Wixon J, et al. Gene therapy clinical trials worldwide 1989-2004-an overview. J Gene Med. 2004; 6: 597-602.
-
(2004)
J Gene Med
, vol.6
, pp. 597-602
-
-
Edelstein, M.L.1
Abedi, M.R.2
Wixon, J.3
-
6
-
-
34249890562
-
Gene therapy for severe combined immunodeficiency: Are we there yet?
-
Cavazzana-Calvo M, Fischer A. Gene therapy for severe combined immunodeficiency: are we there yet? J Clin Invest. 2007; 117: 1456-65.
-
(2007)
J Clin Invest
, vol.117
, pp. 1456-1465
-
-
Cavazzana-Calvo, M.1
Fischer, A.2
-
7
-
-
0032823303
-
Next-generation adenoviral vectors: New and improved
-
Amalfitano A. Next-generation adenoviral vectors: new and improved. Gene Therapy. 1999; 6: 1643-5.
-
(1999)
Gene Therapy
, vol.6
, pp. 1643-1645
-
-
Amalfitano, A.1
-
8
-
-
0037374228
-
Cell cycle independent infection and gene transfer by recombinant Sendai viruses
-
Armeanu S, Ungerechts G, Bernloehr C, et al. Cell cycle independent infection and gene transfer by recombinant Sendai viruses. J Virol Methods. 2003; 108: 229-33.
-
(2003)
J Virol Methods
, vol.108
, pp. 229-233
-
-
Armeanu, S.1
Ungerechts, G.2
Bernloehr, C.3
-
9
-
-
0036125241
-
Viral approaches to cancer gene therapy
-
Hale SJ and Green NK. Viral approaches to cancer gene therapy. Expert Opin Ther Patents 2002. 12(3): 369-378.
-
(2002)
Expert Opin Ther Patents
, vol.12
, Issue.3
, pp. 369-378
-
-
Hale, S.J.1
Green, N.K.2
-
10
-
-
0037384595
-
Viruses in therapy-royal road or dead end?
-
Dobbelstein M. Viruses in therapy-royal road or dead end? Virus Res. 2003; 92: 219-21.
-
(2003)
Virus Res
, vol.92
, pp. 219-221
-
-
Dobbelstein, M.1
-
12
-
-
0036560326
-
Intracellular barriers to non-viral gene transfer
-
Lechardeur D, Lukacs GL. Intracellular barriers to non-viral gene transfer. Curr Gene Ther. 2002; 2: 183-94.
-
(2002)
Curr Gene Ther
, vol.2
, pp. 183-194
-
-
Lechardeur, D.1
Lukacs, G.L.2
-
13
-
-
1642374013
-
Membrane interaction and cellular internalization of penetratin peptides
-
Christiaens B, Grooten J, Reusens M, et al. Membrane interaction and cellular internalization of penetratin peptides. European Journal of Biochemistry. 2004; 271: 1187-97.
-
(2004)
European Journal of Biochemistry
, vol.271
, pp. 1187-1197
-
-
Christiaens, B.1
Grooten, J.2
Reusens, M.3
-
14
-
-
0036159271
-
Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat
-
Silhol M, Tyagi M, Giacca M, et al. Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat. Eur J Biochem. 2002; 269: 494-501.
-
(2002)
Eur J Biochem
, vol.269
, pp. 494-501
-
-
Silhol, M.1
Tyagi, M.2
Giacca, M.3
-
15
-
-
0030904245
-
A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
-
Vives E, Brodin P, Lebleu B. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J Biol Chem. 1997; 272: 16010-7.
-
(1997)
J Biol Chem
, vol.272
, pp. 16010-16017
-
-
Vives, E.1
Brodin, P.2
Lebleu, B.3
-
16
-
-
0041816277
-
Antennapedia and HIV transactivator of transcription (TAT) "protein transduction domains" promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans
-
Console S, Marty C, Garcia-Echeverria C, et al. Antennapedia and HIV transactivator of transcription (TAT) "protein transduction domains" promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans. J Biol Chem. 2003; 278: 35109-14.
-
(2003)
J Biol Chem
, vol.278
, pp. 35109-35114
-
-
Console, S.1
Marty, C.2
Garcia-Echeverria, C.3
-
17
-
-
0035989846
-
Cell-dependent differential cellular uptake of PNA, peptides, and PNA- peptide conjugates. Antisense Nucleic Acid
-
Koppelhus U, Awasthi SK, Zachar V, et al. Cell-dependent differential cellular uptake of PNA, peptides, and PNA- peptide conjugates. Antisense Nucleic Acid Drug D. 2002; 12: 51-63.
-
(2002)
Drug D
, vol.12
, pp. 51-63
-
-
Koppelhus, U.1
Awasthi, S.K.2
Zachar, V.3
-
18
-
-
0031033760
-
Accessibility of nuclear DNA to triplex-forming oligonucleotides: The integrated HIV-1 provirus as a target
-
Giovannangeli C, Diviacco S, Labrousse V, et al. Accessibility of nuclear DNA to triplex-forming oligonucleotides: the integrated HIV-1 provirus as a target. Proc Natl Acad Sci U S A. 1997; 94: 79-84.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 79-84
-
-
Giovannangeli, C.1
Diviacco, S.2
Labrousse, V.3
-
19
-
-
11144356131
-
The use of cell-penetrating peptides as a tool for gene regulation
-
Jarver P, Langel U. The use of cell-penetrating peptides as a tool for gene regulation. Drug Discov Today. 2004; 9: 395-402.
-
(2004)
Drug Discov Today
, vol.9
, pp. 395-402
-
-
Jarver, P.1
Langel, U.2
-
20
-
-
0034237577
-
-
Schwarze SR, Hruska KA, Dowdy SF. Protein transduction: unrestricted delivery into all cells? Tr Cell Biol. 2000; 10: 290-5.
-
Schwarze SR, Hruska KA, Dowdy SF. Protein transduction: unrestricted delivery into all cells? Tr Cell Biol. 2000; 10: 290-5.
-
-
-
-
21
-
-
0028054797
-
Tat-mediated delivery of heterologous proteins into cells
-
Fawell S, Seery J, Daikh Y, et al. Tat-mediated delivery of heterologous proteins into cells. Proc Natl Acad Sci U S A. 1994; 91: 664-8.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 664-668
-
-
Fawell, S.1
Seery, J.2
Daikh, Y.3
-
22
-
-
0032922213
-
Intercellular trafficking of VP22-GFP fusion proteins
-
Elliott G, O'Hare P. Intercellular trafficking of VP22-GFP fusion proteins. Gene Ther. 1999; 6: 149-51.
-
(1999)
Gene Ther
, vol.6
, pp. 149-151
-
-
Elliott, G.1
O'Hare, P.2
-
23
-
-
0031953510
-
Intercellular delivery of functional p53 by the herpesvirus protein VP22 [see comments]
-
Phelan A, Elliott G, O'Hare P. Intercellular delivery of functional p53 by the herpesvirus protein VP22 [see comments]. Nat Biotechnol. 1998; 16: 440-3.
-
(1998)
Nat Biotechnol
, vol.16
, pp. 440-443
-
-
Phelan, A.1
Elliott, G.2
O'Hare, P.3
-
24
-
-
0031984072
-
Trojan peptides: The penetratin system for intracellular delivery
-
Derossi D, Chassaing G, Prochiantz A. Trojan peptides: the penetratin system for intracellular delivery. Tr Cell Biol. 1998; 8: 84-7.
-
(1998)
Tr Cell Biol
, vol.8
, pp. 84-87
-
-
Derossi, D.1
Chassaing, G.2
Prochiantz, A.3
-
26
-
-
34250835903
-
A comprehensive model for the cellular uptake of cationic cell-penetrating peptides
-
Duchardt F, Fotin-Mleczek M, Schwarz H, et al. A comprehensive model for the cellular uptake of cationic cell-penetrating peptides. Traffic. 2007; 8: 848-66.
-
(2007)
Traffic
, vol.8
, pp. 848-866
-
-
Duchardt, F.1
Fotin-Mleczek, M.2
Schwarz, H.3
-
27
-
-
39149103400
-
The design of guanidinium-rich transporters and their internalization mechanisms
-
Wender PA, Galliher WC, Goun EA, et al. The design of guanidinium-rich transporters and their internalization mechanisms. Adv Drug Deliv Rev. 2008; 60: 452-72.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 452-472
-
-
Wender, P.A.1
Galliher, W.C.2
Goun, E.A.3
-
28
-
-
0027243393
-
Neurotrophic activity of an homeobox peptide
-
Joliot A, Le Roux I, Volovitch M, et al. Neurotrophic activity of an homeobox peptide. Ann Genet. 1993; 36: 70-2.
-
(1993)
Ann Genet
, vol.36
, pp. 70-72
-
-
Joliot, A.1
Le Roux, I.2
Volovitch, M.3
-
29
-
-
0037440187
-
Cellular uptake of Antennapedia Penetratin peptides is a two-step process in which phase transfer precedes a tryptophan-dependent translocation
-
Dom G, Shaw-Jackson C, Matis C, et al. Cellular uptake of Antennapedia Penetratin peptides is a two-step process in which phase transfer precedes a tryptophan-dependent translocation. Nucleic Acids Res. 2003; 31: 556-61.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 556-561
-
-
Dom, G.1
Shaw-Jackson, C.2
Matis, C.3
-
31
-
-
0038387344
-
TAT peptide internalization: Seeking the mechanism of entry. Current Protein & Peptide
-
Vives E, Richard JP, Rispal C, et al. TAT peptide internalization: Seeking the mechanism of entry. Current Protein & Peptide Science. 2003; 4: 125-32.
-
(2003)
Science
, vol.4
, pp. 125-132
-
-
Vives, E.1
Richard, J.P.2
Rispal, C.3
-
32
-
-
5444264410
-
Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans
-
Song Y, Tong Z, Wang J, et al. Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans. DNA Res. 2004; 11: 179-97.
-
(2004)
DNA Res
, vol.11
, pp. 179-197
-
-
Song, Y.1
Tong, Z.2
Wang, J.3
-
33
-
-
0031593188
-
Synthesis of biodegradable polymers for controlled drug release
-
Ulbrich K, Pechar M, Strohalm J, et al. Synthesis of biodegradable polymers for controlled drug release. Ann N Y Acad Sci. 1997; 831: 47-56.
-
(1997)
Ann N Y Acad Sci
, vol.831
, pp. 47-56
-
-
Ulbrich, K.1
Pechar, M.2
Strohalm, J.3
-
34
-
-
0041181628
-
HPMA copolymer-anticancer drug conjugates: Design, activity, and mechanism of action
-
Kopecek J, Kopeckova P, Minko T, et al. HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action. Eur J Pharm Biopharm. 2000; 50: 61-81.
-
(2000)
Eur J Pharm Biopharm
, vol.50
, pp. 61-81
-
-
Kopecek, J.1
Kopeckova, P.2
Minko, T.3
-
36
-
-
0034016185
-
Genome changes and gene expression in human solid tumors
-
Gray JW, Collins C. Genome changes and gene expression in human solid tumors. Carcinogenesis. 2000; 21: 443-52.
-
(2000)
Carcinogenesis
, vol.21
, pp. 443-452
-
-
Gray, J.W.1
Collins, C.2
-
37
-
-
20744456789
-
Solid Phase Peptide Synthesis. I The Synthesis of a Tetrapeptide
-
Merriefield RB. Solid Phase Peptide Synthesis. I The Synthesis of a Tetrapeptide. J Americ Chem Soc. 1963; 85: 2149-54.
-
(1963)
J Americ Chem Soc
, vol.85
, pp. 2149-2154
-
-
Merriefield, R.B.1
-
38
-
-
0041902735
-
Complex polyfluoride additives in Fmoc-amino acid fluoride coupling processes. Enhanced reactivity and avoidance of stereomutation
-
Carpino LA, Ionescu D, El Faham A, et al. Complex polyfluoride additives in Fmoc-amino acid fluoride coupling processes. Enhanced reactivity and avoidance of stereomutation. Org Lett. 2003; 5: 975-7.
-
(2003)
Org Lett
, vol.5
, pp. 975-977
-
-
Carpino, L.A.1
Ionescu, D.2
El Faham, A.3
-
39
-
-
33749822314
-
Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems
-
Lammers T, Peschke P, Kuhnlein R, et al. Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems. Neoplasia. 2006; 8: 788-95.
-
(2006)
Neoplasia
, vol.8
, pp. 788-795
-
-
Lammers, T.1
Peschke, P.2
Kuhnlein, R.3
-
40
-
-
0025257556
-
Amplified RNA synthesized from limited quantities of heterogeneous cDNA
-
Van Gelder RN, von Zastrow ME, Yool A, et al. Amplified RNA synthesized from limited quantities of heterogeneous cDNA. Proc Natl Acad Sci U S A. 1990; 87: 1663-7.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 1663-1667
-
-
Van Gelder, R.N.1
von Zastrow, M.E.2
Yool, A.3
-
41
-
-
34248359155
-
MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity
-
Wiley SE, Murphy AN, Ross SA, et al. MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity. Proc Natl Acad Sci U S A. 2007; 104: 5318-23.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 5318-5323
-
-
Wiley, S.E.1
Murphy, A.N.2
Ross, S.A.3
-
42
-
-
35448995690
-
MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone
-
Paddock ML, Wiley SE, Axelrod HL, et al. MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone. Proc Natl Acad Sci U S A. 2007; 104: 14342-7.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 14342-14347
-
-
Paddock, M.L.1
Wiley, S.E.2
Axelrod, H.L.3
-
43
-
-
34249672284
-
Up-regulation of myometrial RHO effector proteins (PKN1 and DIAPH1) and CPI-17 (PPP1R14A) phosphorylation in human pregnancy is associated with increased GTP-RHOA in spontaneous preterm labor
-
Lartey J, Smith M, Pawade J, et al. Up-regulation of myometrial RHO effector proteins (PKN1 and DIAPH1) and CPI-17 (PPP1R14A) phosphorylation in human pregnancy is associated with increased GTP-RHOA in spontaneous preterm labor. Biol Reprod. 2007; 76: 971-82.
-
(2007)
Biol Reprod
, vol.76
, pp. 971-982
-
-
Lartey, J.1
Smith, M.2
Pawade, J.3
-
44
-
-
45849148842
-
The role of extracellular matrix metalloproteinase inducer protein in prostate cancer progression
-
Madigan MC, Kingsley EA, Cozzi PJ, et al. The role of extracellular matrix metalloproteinase inducer protein in prostate cancer progression. Cancer Immunol Immunother. 2008; 57: 1367-79.
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 1367-1379
-
-
Madigan, M.C.1
Kingsley, E.A.2
Cozzi, P.J.3
-
45
-
-
50049125630
-
The role of BSG (CD147) in acute lymphoblastic leukaemia and relapse
-
Beesley AH, Weller RE, Kees UR. The role of BSG (CD147) in acute lymphoblastic leukaemia and relapse. Br J Haematol. 2008 142(6):1000-2.
-
(2008)
Br J Haematol
, vol.142
, Issue.6
, pp. 1000-1002
-
-
Beesley, A.H.1
Weller, R.E.2
Kees, U.R.3
-
46
-
-
34247197062
-
Tumor vesicle-associated CD147 modulates the angiogenic capability of endothelial cells
-
Millimaggi D, Mari M, D'Ascenzo S, et al. Tumor vesicle-associated CD147 modulates the angiogenic capability of endothelial cells. Neoplasia. 2007; 9: 349-57.
-
(2007)
Neoplasia
, vol.9
, pp. 349-357
-
-
Millimaggi, D.1
Mari, M.2
D'Ascenzo, S.3
-
47
-
-
38949201715
-
EMMPRIN expression as a prognostic factor in radiotherapy of cervical cancer
-
Ju XZ, Yang JM, Zhou XY, et al. EMMPRIN expression as a prognostic factor in radiotherapy of cervical cancer. Clin Cancer Res. 2008; 14: 494-501.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 494-501
-
-
Ju, X.Z.1
Yang, J.M.2
Zhou, X.Y.3
|