Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 689, Issue 1-2, 2010, Pages 12-20

  Wilson, James B ^a   Blom, Eric ^b   Cunningham, Ryan ^a   Xiao, Yuxuan ^a   Kupfer, Gary M ^c   Jones, Nigel J ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

FANCG; Fanconi anaemia; Homologous recombination; Radiomimetic; SH3 domain; Tetratricopeptide motif

Indexed keywords

BRCA2 PROTEIN; FANCONI ANEMIA GROUP A PROTEIN; FANCONI ANEMIA GROUP D2 PROTEIN; FANCONI ANEMIA GROUP F PROTEIN; FANCONI ANEMIA GROUP G PROTEIN; HYBRID PROTEIN; ISOPROTEIN; MITOMYCIN C; PHLEOMYCIN; PROTEIN D1 D2 G X3; PROTEIN TPR1; PROTEIN TPR2; PROTEIN TPR5; PROTEIN TPR6; SERINE; UNCLASSIFIED DRUG; XRCC3 PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG RESISTANCE; FANCONI ANEMIA; FEMALE; GENE MUTATION; HAMSTER; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; TETRATRICOPEPTIDE REPEAT; UBIQUITINATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BRCA2 PROTEIN; CHO CELLS; CRICETINAE; CRICETULUS; DNA-BINDING PROTEINS; FANCONI ANEMIA COMPLEMENTATION GROUP D2 PROTEIN; FANCONI ANEMIA COMPLEMENTATION GROUP G PROTEIN; HUMANS; MICE; MUTATION; NUCLEIC ACID SYNTHESIS INHIBITORS; PHLEOMYCINS; RECOMBINATION, GENETIC; TRANSFECTION; UBIQUITINATION;

CRICETULUS GRISEUS;

EID: 77953913369     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2010.04.003     Document Type: Article

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