The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG

Human Molecular Genetics

Volumn 9, Issue 18, 2000, Pages 2665-2674

  De Winter, Johan P ^a   Van Der Weel, Laura ^a   De Groot, Jan ^a   Stone, Stacie ^b   Waisfisz, Quinten ^a   Arwert, Fré ^a   Scheper, Rik J ^a   Kruyt, Frank A E ^a   Hoatlin, Maureen E ^b   Joenje, Hans ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FANCONI ANEMIA GROUP A PROTEIN; FANCONI ANEMIA GROUP C PROTEIN; FANCONI ANEMIA GROUP F PROTEIN; FANCONI ANEMIA GROUP G PROTEIN; NUCLEAR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL NUCLEUS; COMPLEX FORMATION; CONTROLLED STUDY; FANCONI ANEMIA; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; LYMPHOBLAST; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

EID: 0034326299     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/9.18.2665     Document Type: Article

References (36)

1. Fanconi anemia
2. The cell cycle of lymphocytes in Fanconi anemia
3. Flow cytometric characterization of the response of Fanconi's anemia cells to mitomycin C treatment
4. Cancer-susceptibility genes. Gatekeepers and caretakers
5. Evidence for at least eight Fanconi anemia genes
6. Complementation analysis in Fanconi anemia: Assignment of the reference FA-H patient to group A
7. Cloning of cDNAs for Fanconi's anemia by functional complementation
8. Positional cloning of Fanconi anemia group A gene
9. Expression cloning of a cDNA for the major Fanconi anemia gene, FAA
10. The Fanconi anemia group G gene FANCG is identical with XRCC9
11. The Fanconi anaemia gene FANCF encodes a novel protein with homology to ROM
12. Microcell mediated chromosome transfer maps the Fanconi anemia group D gene to chromosome 3p
13. Localization of the Fanconi anemia complementation group D gene to a 200-kb region on chromosome 3p25.3
14. The Fanconi anemia group E gene, FANCE, maps to chromosome 6p
15. The Fanconi anemia polypeptide FACC is localized to the cytoplasm
16. Localization of Fanconi anemia C protein to the cytoplasm of mammalian cells
17. The Fanconi anemia proteins, FAA and FAC interact to form a nuclear complex
18. The Fanconi anemia group C gene product is located in both the nucleus and cytoplasm of human cells
19. The Fanconi anemia proteins FAA and FAC function in different cellular compartments to protect against cross-linking agent cytotoxicity
20. Functional activity of the Fanconi anemia protein FAA requires FAC binding and nuclear localization
21. Characterization of regions functional in the nuclear localization of the Fanconi anemia group a protein
22. Fanconi anemia proteins FANCA, FANCC and FANCG/XRCC9 interact in a functional nuclear complex
23. Resistance to mitomycin C requires direct interaction between the Fanconi anemia proteins FANCA and FANCG in the nucleus through an arginine-rich domain
24. A physical complex of the Fanconi anemia proteins FANCG/XRCC9 and FANCA
25. The Fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation
26. A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF
27. A patient-derived mutant form of the Fanconi anemia protein, FANCA, is defective in nuclear accumulation
28. Nuclear localization of the Fanconi anemia protein FANCC is required for functional activity
29. Cytoplasmic localization of of FAC is essential for the correction of a prerepair defect in Fanconi anemia group C cells
30. Abnormal microsomal detoxification implicated in Fanconi anemia group C by interaction of the FAC protein with NADPH cytochrome P450 reductase
31. Flourescence microphotolysis to measure nucleocytoplasmic transport and intracellular mobility
32. A cytoplasmic serine protein kinase binds, phosphorylates and regulates the function of the Fanconi anemia protein FANCA
33. Isolation of a cDNA representing the Fanconi anemia complementation group E gene
34. Susceptibility of Fanconi's anemia lymphoblasts to DNA cross-linking and alkylating agents
35. Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase
36. Immunoglobulin-producing hybrid cell lines