Propranolol regulates cardiac transient outward potassium channel in rat myocardium via cAMP/PKA after short-term but not after long-term ischemia

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 382, Issue 1, 2010, Pages 63-71

  Zhang, Li ^a   Xu, Chao Qian ^a   Hong, Yuan ^a   Zhang, Jia Lin ^a   Liu, Ying ^a   Zhao, Mei ^a   Cao, Yan Xiu ^a   Lu, Yan Jie ^a   Yang, Bao Feng ^a   Shan, Hong Li ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

cAMP PKA; Kv4.2; Myocardial infarction; Propranolol; Transient outward potassium current

Indexed keywords

AMIODARONE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; POTASSIUM CHANNEL; POTASSIUM CHANNEL KV1.2; PROPRANOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; SHAL POTASSIUM CHANNEL;

ACUTE HEART INFARCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAUSE OF DEATH; CELL PROTECTION; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DISEASE COURSE; HEART ARRHYTHMIA; HEART INFARCTION; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; MORTALITY; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WHOLE CELL; ANIMAL; DISEASE MODEL; DRUG ADMINISTRATION; DRUG EFFECTS; METABOLISM; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; PATCH CLAMP TECHNIQUE; PATHOPHYSIOLOGY; TIME; WISTAR RAT;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; BLOTTING, WESTERN; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PROPRANOLOL; RATS; RATS, WISTAR; SHAL POTASSIUM CHANNELS; TIME FACTORS;

EID: 77953873163     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-010-0520-y     Document Type: Article

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