The thyroid hormone analog DITPA restores I(to) in rats after myocardial infarction

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 278, Issue 4 47-4, 2000, Pages

  Wickenden, Alan D ^a,b   Kaprielian, Roger ^a   You, X Y Xiao Mang ^a   Backx, Peter H ^a  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b Icagen Inc   (United States)

Author keywords

3,5 diiodothyropropionic acid; Action potential; Kv1.4; Kv4.2; Kv4.3; Transient outward current

Indexed keywords

3,5 DIIODOTHYROPROPRIONIC ACID; CALCIUM ION; POTASSIUM ION; THYROID HORMONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART INFARCTION; HEART MUSCLE POTENTIAL; HEART VENTRICLE REMODELING; HORMONAL REGULATION; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 0034058812     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2000.278.4.h1105     Document Type: Article

References (50)

1. Afzal, N., and N. S. Dhalla. Differential changes in left and right ventricular SR calcium transport in congestive heart failure. Am. J. Physiol. Heart Circ. Physiol. 262: H868-H874, 1992.
2. Agus Z. S., I. D. Dukes, and M. Morad. Divalent cations modulate the transient outward current in rat ventricular myocytes. Am. J. Physiol. Cell Physiol. 261: C310-C318, 1991.
3. Anversa P., A. V. Loud, V. Levicky, and G. Guideri. Left ventricular failure induced by myocardial infarction. I. Myocyte hypertrophy. Am. J. Physiol. Heart Circ. Physiol. 248: H876-H882, 1985.
4. Binah, O., I. Rubinstein, and E. Gilat. Effects of thyroid hormone on the action potential and membrane currents of guinea pig ventricular myocytes. Pflügers Arch. 409: 214-216, 1987.
5. 2+ exchanger expression during postnatal maturation and in adult rabbit ventricular myocardium. Cardiovasc. Res. 31: E145-E152, 1996.
6. 2+-ATPase in developing rat heart. Am. J. Physiol. Heart Circ. Physiol. 275: H264-H273, 1998.
7. Chien, K. R., K. U. Knowlton, H. Zhu, and S. Chen. Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response. FASEB J. 5: 3037-3046, 1991.
8. Chomczynski, P., and M. Sacchi. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
9. Clark, R. B., R. A. Bouchard, E. Salinas-Stefanon, J. Sanchez-Chapula, and W. R. Giles. Heterogeneity of action potential waveforms and potassium currents in rat ventricle Cardiovasc. Res. 27: 1795-1799, 1993.
10. Dixon, J. E., and D. McKinnon. Quantitative analysis of potassium channel mRNA expression in atrial and ventricular muscle of rats. Circ. Res. 75: 252-260, 1994.
11. + channel in ventricular muscle: a molecular correlate for the transient outward current. Circ. Res. 79: 659-668, 1996.
12. Dorian P., F. X. Witkowski, P. A. Penkoske, and R. S. Feder-Elituv. Barium decreases defibrillation energy requirements. J. Cardiovasc. Pharmacol. 23: 107-112, 1994.
13. Franz, M. R. Current status of monophasic action potential recording: theories, measurements and interpretations. Cardiovasc. Res. 41: 25-40, 1999.
14. Gay, R. G., S. Graham, M. Aguirre, S. Goldman, and E. Morkin. Effects of 10-to 12-day treatment with L-thyroxine in rats with myocardial infarction. Am. J. Physiol. Heart Circ. Physiol. 255: H801-H806, 1988.
15. + channel genes in left ventricular remodeled myocardium after experimental myocardial infarction. Circ. Res. 79: 669-675, 1996.
16. Gomez, A.-M., J.-P. Benitah, D. Henzel, A. Vinet, P. Lorente, and C. Delgado. Modulation of electrical heterogeneity by compensated hypertrophy in rat left ventricle. Am. J. Physiol. Heart Circ. Physiol. 272: H1078-H1086, 1997.
17. + channel expression by myocardial hypertrophic factors in cultured newborn rat ventricular cells. J. Mol. Cell. Cardiol. 30: 1449-1455, 1998.
18. Hamill, O. P., A. Marty, B. Neher, B. Sakmann, and F. J. Sigworth. Improved patch clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch. 391: 85-100, 1981.
19. Izumo, S., A.-M Lompre, R. Matsuoka, G. Koren, K. Schwartz, B. Nadal-Ginard, and V. Mahdavi. Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy. Interactions between hemodynamic and thyroid hormone-induced signals. J. Clin. Invest. 79: 970-977, 1987.
20. Kääb, S., B. Nuss, N. Chiamvimonvat, B. O'Rourke, P. H. Pak, D. A. Kass, E. Marban, and G. F. Tomaselli. Ionic mechanism of action potential prolongation in ventricular myocytes from dogs with pacing-induced heart failure. Circ. Res. 78: 262-273, 1996.
21. i in rat ventricular myocytes following myocardial infarction. J. Physiol. (Lond.) 517: 229-245, 1999.
22. Lefevre, I. A., A. Coulombe, and E. Coraboeuf. The calcium antagonist D600 inhibits calcium-independent transient outward current in isolated rat ventricular myocytes. J. Physiol. (Lond.) 432: 65-80, 1991.
23. Litovsky, S. H., and C. Antzelevitch. Transient outward current prominent in canine ventricular epicardium but not endocardium. Circ. Res. 62: 116-126, 1988.
24. 2+ exchange in the infarcted heart. Implications for excitation-contraction coupling. Circ. Res. 81: 1083-1093, 1997.
25. Mahaffy, K. W., T. E. Raya, G. D. Pennock, E. Morkin, and S. Goldman. Left ventricular performance and remodeling in rabbits after myocardial infarction. Effects of a thyroid hormone analogue. Circulation 91: 794-802, 1995.
26. Matsubara, H., J. Suzuki, and M. Inada. Shaker-related potassium channel, Kv1.4, mRNA regulation in cultured rat heart myocytes and differential expression Kv1.4 and Kv1.5 genes in myocardial development and hypertrophy. J. Clin. Invest. 92: 1659-1666, 1993.
27. Näbauer, M., D. J. Beuckelmann, P. Uberfuhr, and G. Steinbeck. Regional differences in current density and rate-dependent properties of the transient outward current in subepicardial and subendocardial myocytes of human left ventricle. Circulation 93: 168-177, 1996.
28. Näbauer, M., and S. Kääb. Potassium channel down-regulation in heart failure. Cardiovasc. Res. 37: 324-334, 1998.
29. Nishiyama, A., F. Kambe, K. Kamiya, H. Seo, and J. Toyama. Effects of thyroid status on expression of voltage-gated potassium channels in rat left ventricle. Cardiovasc. Res. 40: 343-351, 1998.
30. Orenstein, T. L., T. G. Parker, J. Butany, J. M. Goodman, F. Dawood, W.-H. Wen, L. Wee, T. Martino, P. R. McLaughlin, and P. P. Liu. Favorable left ventricular remodeling following large myocardial infarction by exercise training. Effect on ventricular morphology and gene expression. J. Clin. Invest. 96: 858-866, 1995.
31. Pennock, G. D., T. E. Raya, J. J. Bahl, S. Goldman, and E. Morkin. Cardiac effects of 3,5-diiodothyropropionic acid, a thyroid analogue with inotropic selectivity. J. Pharmacol. Exp. Ther. 263: 163-169, 1992.
32. Pennock, G. D., T. E. Raya, J. J. Bahl, S. Goldman, and E. Morkin. Combination treatment with captopril and the thyroid hormone analogue 3,5-diiodothyropropionic acid. A new approach to improving left ventricular performance in heart failure. Circulation 88: 1289-1298, 1993.
33. Pfeffer, M. A., J. M. Pfeffer, M. C. Fishbein, P. J. Fletcher, J. Spadaro, R. A. Kloner, and E. Braunwald. Myocardial infarct size and ventricular function in rats. Circ. Res. 44: 503-512, 1979.
34. Pinto, J. M. B., and P. A. Boyden. Electrical remodeling in ischemia and infarction. Cardiovasc. Res. 42: 284-297, 1999.
35. Qin, D., Z. H. Zhang, E. B. Caref, M. Boutjdir, P. Jain, and N. El-Sherif. Cellular and ionic basis of arrhythmias in post-infarction remodeled ventricular myocardium. Circ. Res. 79: 461-473, 1996.
36. Scheuer, J., and P. Buttrick. The cardiac hypertrophic response to pathologic and physiologic loads. Circulation 75, Suppl. I: I-63-I-68, 1987.
37. Sethi, R., K. S. Dhalla, R. E. Beamish, and N. S. Dhalla. Differential changes in left and right ventricular adenylyl cyclase activities in congestive heart failure. Am. J. Physiol. Heart Circ. Physiol. 272: H884-H893, 1997.
38. Shimoni, Y., H. Banno, and R. B. Clark. Hyperthyroidism selectively modifies a transient potassium current in rabbit ventricular and atrial myocytes. J. Physiol. (Lond.) 457: 369-389, 1992.
39. + channe isoforms in rat ventricle. J. Physiol. (Lond.) 500: 65-73, 1997.
40. Tomaselli, G. F., D. J. Beuckelmann, H. G. Calkins, R. D. Berger, P. D. Kassler, J. H. Lawrence, D. Kass, A. M. Feldman, and E. Marban. Sudden cardiac death in heart failure. The role of abnormal repolarization. Circulation 90: 2534-2539, 1994.
41. Tsoporis, J. N., A. Marks, H. J. Kahn, J. W. Butany, P. P. Liu, D. O'Hanlon, and T. G. Parker. S100 beta inhibits alpha1-adrenergic induction of the hypertrophic phenotype. J. Biol. Chem. 272 50: 31915-31921, 1997.
42. + current in rat ventricle. Am. J. Physiol. Heart Circ. Physiol. 276: H1599-H1607, 1999.
43. + channel expression and repolarization in hypertrophied rat ventricular myocytes. Circulation 98:I-1808, 1998.
44. Wickenden, A. D., R. Kaprielian, Z. Kassiri, J. N. Tsoporis, R. Tsushima, G. I. Fishman, and P. H. Backx. The role of action potential prolongation and elevated intracellular calcium in the pathogenesis of heart failure. Cardiovasc. Res. 37: 312-323, 1998.
45. + channel gene expression in rat ventricle. J. Physiol. (Lond.) 504: 271-286, 1997.
46. 2+ on Kv4.2 and Kv1 expressed in Xenopus oocytes and on the transient outward currents in rat and rabbit ventricular myocytes. Cell Physiol. Biochem. 9: 11-28, 1999.
47. + channel currents in rat ventricular myocytes. J. Gen. Physiol. 108: 405-419, 1996.
48. Young, R. L., A. L. Grundlach, and W. J. Louis. Altered cardiac hormone and contractile protein messenger RNA levels following left ventricular myocardial infarction in the rat: an in situ hybridization histochemical study. Cardiovasc. Res. 37: 187-201, 1998.
49. Yu, C. M., J. E. Sanderson, S. Chan, L. Yeung, Y. T. Hung, and K. S. Woo. Right ventricular diastolic dysfunction in heart failure. Circulation 93: 1509-1514, 1996.
50. i transients hypertensive and post-infarction. Am. J. Physiol. Cell Physiol. 269: C632-C640, 1995.