The transmembrane β-subunits KCNE1, KCNE2, and DPP6 modify pharmacological effects of the antiarrhythmic agent tedisamil on the transient outward current i to

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 379, Issue 6, 2009, Pages 617-626

  Radicke, Susanne ^a,b   Cotella, Diego ^b   Sblattero, Daniele ^b   Ravens, Ursula ^a   Santoro, Claudio ^b   Wettwer, Erich ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

DPP6; I to; KCNE1; KCNE2; Kv4.3; Tedisamil; Transient outward current

Indexed keywords

DIPEPTIDYL AMINOPEPTIDASE LIKE PROTEIN 6; POTASSIUM CHANNEL KCNE1; POTASSIUM CHANNEL KCNE2; PROTEIN; TEDISAMIL; UNCLASSIFIED DRUG; ANTIARRHYTHMIC AGENT; CYCLOPROPANE DERIVATIVE; DIPEPTIDYL PEPTIDASE; DPP6 PROTEIN, HUMAN; FUSED HETEROCYCLIC RINGS; KCNE1 PROTEIN, HUMAN; KCNE2 PROTEIN, HUMAN; NERVE PROTEIN; POTASSIUM CHANNEL; PROTEIN SUBUNIT; SHAL POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL CELL; AREA UNDER THE CURVE; ARTICLE; BETA CHAIN; CELL CULTURE; CHO CELL; CONTROLLED STUDY; DRUG BINDING; ELECTROPHYSIOLOGY; GENETIC TRANSFECTION; IC 50; NONHUMAN; PROTEIN DOMAIN; ANIMAL; ANTAGONISTS AND INHIBITORS; CHO CELL LINE; COMPARATIVE STUDY; CRICETULUS; DOSE RESPONSE; DRUG EFFECTS; HAMSTER; HUMAN; MEMBRANE POTENTIAL; METABOLISM; PHYSIOLOGY; PROTEIN SUBUNIT;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; BICYCLO COMPOUNDS, HETEROCYCLIC; CHO CELLS; CRICETINAE; CRICETULUS; CYCLOPROPANES; DIPEPTIDYL-PEPTIDASES AND TRIPEPTIDYL-PEPTIDASES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MEMBRANE POTENTIALS; NERVE TISSUE PROTEINS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN SUBUNITS; SHAL POTASSIUM CHANNELS;

EID: 64749104755     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-008-0389-1     Document Type: Article

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