메뉴 건너뛰기




Volumn 82, Issue 5, 2010, Pages 921-929

Function-specific intracellular signaling pathways downstream of heparin-binding EGF-like growth factor utilized by human trophoblasts

Author keywords

AKT; Apoptosis; Cell differentiation; Cell migration; Mitogen activated protein kinases; Phosphoinositide 3 kinase; Pregnancy; Signal transduction; Trophoblast

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE;

EID: 77953834068     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.109.082305     Document Type: Article
Times cited : (31)

References (77)
  • 1
    • 0019378232 scopus 로고
    • Review article: Trophoblast invasion and the establishment of haemochorial placentation in man and laboratory animals
    • Pijnenborg R, Robertson WB, Brosens I, Dixon G. Review article: trophoblast invasion and the establishment of haemochorial placentation in man and laboratory animals. Placenta 1981; 2:71-91. (Pubitemid 11179363)
    • (1981) Placenta , vol.2 , Issue.1 , pp. 71-91
    • Pijnenborg, R.1    Robertson, W.B.2    Brosens, I.3    Dixon, G.4
  • 2
    • 4444347073 scopus 로고    scopus 로고
    • Placental oxidative stress: From miscarriage to preeclampsia
    • Burton GJ, Jauniaux E. Placental oxidative stress: from miscarriage to preeclampsia. J Soc Gynecol Invest 2004; 11:342-352.
    • (2004) J Soc Gynecol Invest , vol.11 , pp. 342-352
    • Burton, G.J.1    Jauniaux, E.2
  • 3
    • 0035829844 scopus 로고    scopus 로고
    • Implantation and the survival of early pregnancy
    • Norwitz ER, Schust DJ, Fisher SJ. Implantation and the survival of early pregnancy. N Engl J Med 2001; 345:1400-1408.
    • (2001) N Engl J Med , vol.345 , pp. 1400-1408
    • Norwitz, E.R.1    Schust, D.J.2    Fisher, S.J.3
  • 4
    • 0034843821 scopus 로고    scopus 로고
    • In vitro ischemia-reperfusion injury in term human placenta as a model for oxidative stress in pathological pregnancies
    • Hung TH, Skepper JN, Burton GJ. In vitro ischemia-reperfusion injury in term human placenta as a model for oxidative stress in pathological pregnancies. Am J Pathol 2001; 159:1031-1043.
    • (2001) Am J Pathol , vol.159 , pp. 1031-1043
    • Hung, T.H.1    Skepper, J.N.2    Burton, G.J.3
  • 5
    • 0037188944 scopus 로고    scopus 로고
    • Hypoxiareoxygenation: A potent inducer of apoptotic changes in the human placenta and possible etiological factor in preeclampsia
    • Hung TH, Skepper JN, Charnock-Jones DS, Burton GJ. Hypoxiareoxygenation: a potent inducer of apoptotic changes in the human placenta and possible etiological factor in preeclampsia. Circ Res 2002; 90:1274-1281.
    • (2002) Circ Res , vol.90 , pp. 1274-1281
    • Hung, T.H.1    Skepper, J.N.2    Charnock-Jones, D.S.3    Burton, G.J.4
  • 6
    • 1342323632 scopus 로고    scopus 로고
    • ErbB Receptors: Directing Key Signaling Networks Throughout Life
    • DOI 10.1146/annurev.pharmtox.44.101802.121440
    • Holbro T, Hynes NE. ErbB receptors: directing key signaling networks throughout life. Annu Rev Pharmacol Toxicol 2004; 44:195-217. (Pubitemid 38263839)
    • (2004) Annual Review of Pharmacology and Toxicology , vol.44 , pp. 195-217
    • Holbro, T.1    Hynes, N.E.2
  • 7
    • 0031936410 scopus 로고    scopus 로고
    • Specificity within the EGF family/ErbB receptor family signaling network
    • Riese DJ, Stern DF. Specificity within the EGF family/ErbB receptor family signaling network. Bioessays 1998; 20:41-48.
    • (1998) Bioessays , vol.20 , pp. 41-48
    • Riese, D.J.1    Stern, D.F.2
  • 9
    • 0027457182 scopus 로고
    • Immunohistochemical localization of transforming growth factor-alpha in human endometrium, decidua, and trophoblast
    • Horowitz GM, Scott RT Jr, Drews MR, Navot D, Hofmann GE. Immunohistochemical localization of transforming growth factor-alpha in human endometrium, decidua, and trophoblast. J. Clin. Endocrinol. Metab. 1993; 76:786-792.
    • (1993) J. Clin. Endocrinol. Metab. , vol.76 , pp. 786-792
    • Horowitz, G.M.1    Scott Jr., R.T.2    Drews, M.R.3    Navot, D.4    Hofmann, G.E.5
  • 10
    • 0033304923 scopus 로고    scopus 로고
    • Multiple roles for heparin-binding epidermal growth factorlike growth factor are suggested by its cell specific expression during the human endometrial cycle and early placentation
    • Leach RE, Khalifa R, Ramirez ND, Das SK, Wang J, Dey SK, Romero R, Armant DR. Multiple roles for heparin-binding epidermal growth factorlike growth factor are suggested by its cell specific expression during the human endometrial cycle and early placentation. J Clin Endocrinol Metab 1999; 84:3355-3363.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3355-3363
    • Leach, R.E.1    Khalifa, R.2    Ramirez, N.D.3    Das, S.K.4    Wang, J.5    Dey, S.K.6    Romero, R.7    Armant, D.R.8
  • 11
    • 0036019131 scopus 로고    scopus 로고
    • Regulated expression of heparin-binding EGF-like growth factor (HB-EGF) in the human endometrium: A potential paracrine role during implantation
    • Lessey BA, Gui Y, Apparao KB, Young SL, Mulholland J. Regulated expression of heparin-binding EGF-like growth factor (HB-EGF) in the human endometrium: a potential paracrine role during implantation. Mol Reprod Dev 2002; 62:446-455.
    • (2002) Mol Reprod Dev , vol.62 , pp. 446-455
    • Lessey, B.A.1    Gui, Y.2    Apparao, K.B.3    Young, S.L.4    Mulholland, J.5
  • 12
    • 0030866903 scopus 로고    scopus 로고
    • Temporal and spatial regulation of expression of heparin-binding epidermal growth factor-like growth factor in the human endometrium: A possible role in blastocyst implantation
    • Yoo HJ, Barlow DH, Mardon HJ. Temporal and spatial regulation of expression of heparin-binding epidermal growth factor-like growth factor in the human endometrium: a possible role in blastocyst implantation. Dev Genet 1997; 21:102-108.
    • (1997) Dev Genet , vol.21 , pp. 102-108
    • Yoo, H.J.1    Barlow, D.H.2    Mardon, H.J.3
  • 13
    • 0028216364 scopus 로고
    • Heparin-binding EGF-like growth factor gene is induced in the mouse uterus temporally by the blastocyst solely at the site of its apposition: A possible ligand for interaction with blastocyst EGF-receptor in implantation
    • Das SK, Wang XN, Paria BC, Damm D, Abraham JA, Klagsbrun M, Andrews GK, Dey SK. Heparin-binding EGF-like growth factor gene is induced in the mouse uterus temporally by the blastocyst solely at the site of its apposition: a possible ligand for interaction with blastocyst EGF-receptor in implantation. Development 1994; 120:1071-1083.
    • (1994) Development , vol.120 , pp. 1071-1083
    • Das, S.K.1    Wang, X.N.2    Paria, B.C.3    Damm, D.4    Abraham, J.A.5    Klagsbrun, M.6    Andrews, G.K.7    Dey, S.K.8
  • 15
    • 0033979460 scopus 로고    scopus 로고
    • Acceleration of trophoblast differentiation by heparin-binding EGF-like growth factor is dependent on the stage-specific activation of calcium influx by ErbB receptors in developing mouse blastocysts
    • Wang J, Mayernik L, Schultz JF, Armant DR. Acceleration of trophoblast differentiation by heparin-binding EGF-like growth factor is dependent on the stage-specific activation of calcium influx by ErbB receptors in developing mouse blastocysts. Development 2000; 127:33-44. (Pubitemid 30064386)
    • (2000) Development , vol.127 , Issue.1 , pp. 33-44
    • Wang, J.1    Mayernik, L.2    Schultz, J.F.3    Armant, D.R.4
  • 16
    • 0031833826 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor significantly improves human blastocyst development and hatching in serum-free medium
    • Martin KL, Barlow DH, Sargent IL. Heparin-binding epidermal growth factor significantly improves human blastocyst development and hatching in serum-free medium. Hum Reprod 1998; 13:1645-1652.
    • (1998) Hum Reprod , vol.13 , pp. 1645-1652
    • Martin, K.L.1    Barlow, D.H.2    Sargent, I.L.3
  • 17
    • 0345869896 scopus 로고    scopus 로고
    • Heparinbinding EGF-like growth factor regulates human extravillous cytotrophoblast development during conversion to the invasive phenotype
    • Leach RE, Kilburn BA, Wang J, Liu Z, Romero R, Armant DR. Heparinbinding EGF-like growth factor regulates human extravillous cytotrophoblast development during conversion to the invasive phenotype. Dev Biol 2004; 266:223-237.
    • (2004) Dev Biol , vol.266 , pp. 223-237
    • Leach, R.E.1    Kilburn, B.A.2    Wang, J.3    Liu, Z.4    Romero, R.5    Armant, D.R.6
  • 18
    • 33645047167 scopus 로고    scopus 로고
    • Human trophoblast survival at low oxygen concentrations requires metalloproteinase-mediated shedding of heparin-binding EGF-like growth factor
    • Armant DR, Kilburn BA, Petkova A, Edwin SS, Duniec-Dmuchowski ZM, Edwards HJ, Romero R, Leach RE. Human trophoblast survival at low oxygen concentrations requires metalloproteinase-mediated shedding of heparin-binding EGF-like growth factor. Development 2006; 133:751-759.
    • (2006) Development , vol.133 , pp. 751-759
    • Armant, D.R.1    Kilburn, B.A.2    Petkova, A.3    Edwin, S.S.4    Duniec-Dmuchowski, Z.M.5    Edwards, H.J.6    Romero, R.7    Leach, R.E.8
  • 19
    • 41549096031 scopus 로고    scopus 로고
    • Diminished survival of human cytotrophoblast cells exposed to hypoxia/reoxygenation injury and associated reduction of heparin-binding epidermal growth factor-like growth factor
    • Leach RE, Kilburn BA, Petkova A, Romero R, Armant DR. Diminished survival of human cytotrophoblast cells exposed to hypoxia/reoxygenation injury and associated reduction of heparin-binding epidermal growth factor-like growth factor. Am J Obstet Gynecol 2008; 198:471.e1-471.e8.
    • (2008) Am J Obstet Gynecol , vol.198
    • Leach, R.E.1    Kilburn, B.A.2    Petkova, A.3    Romero, R.4    Armant, D.R.5
  • 20
    • 0027967104 scopus 로고
    • Human cytotrophoblast invasion is up-regulated by epidermal growth factor: Evidence that paracrine factors modify this process
    • Bass KE, Morrish D, Roth I, Bhardwaj D, Taylor R, Zhou Y, Fisher SJ. Human cytotrophoblast invasion is up-regulated by epidermal growth factor: evidence that paracrine factors modify this process. Dev Biol 1994; 164:550-561.
    • (1994) Dev Biol , vol.164 , pp. 550-561
    • Bass, K.E.1    Morrish, D.2    Roth, I.3    Bhardwaj, D.4    Taylor, R.5    Zhou, Y.6    Fisher, S.J.7
  • 21
    • 0029983260 scopus 로고    scopus 로고
    • Epidermal growth factor inhibits cytokine-induced apoptosis of primary human trophoblasts
    • Garcia-Lloret MI, Yui J, Winkler-Lowen B, Guilbert LJ. Epidermal growth factor inhibits cytokine-induced apoptosis of primary human trophoblasts. J Cell Physiol 1996; 167:324-332.
    • (1996) J Cell Physiol , vol.167 , pp. 324-332
    • Garcia-Lloret, M.I.1    Yui, J.2    Winkler-Lowen, B.3    Guilbert, L.J.4
  • 22
    • 0036547596 scopus 로고    scopus 로고
    • Growth factor rescue of cytokine mediated trophoblast apoptosis
    • Smith S, Francis R, Guilbert L, Baker PN. Growth factor rescue of cytokine mediated trophoblast apoptosis. Placenta 2002; 23:322-330.
    • (2002) Placenta , vol.23 , pp. 322-330
    • Smith, S.1    Francis, R.2    Guilbert, L.3    Baker, P.N.4
  • 23
    • 0141614971 scopus 로고    scopus 로고
    • The effect of oxygen tension on intracellular survival signalling in primary villous trophoblasts
    • Mackova M, Kilani RT, Davidge ST, Guilbert LJ. The effect of oxygen tension on intracellular survival signalling in primary villous trophoblasts. Placenta 2003; 24:627-637.
    • (2003) Placenta , vol.24 , pp. 627-637
    • Mackova, M.1    Kilani, R.T.2    Davidge, S.T.3    Guilbert, L.J.4
  • 24
    • 50049109950 scopus 로고    scopus 로고
    • Expression of heparin-binding EGF-like growth factor in term chorionic villous explants and its role in trophoblast survival
    • Imudia AN, Kilburn BA, Petkova A, Edwin SS, Romero R, Armant DR. Expression of heparin-binding EGF-like growth factor in term chorionic villous explants and its role in trophoblast survival. Placenta 2008; 29: 784-789.
    • (2008) Placenta , vol.29 , pp. 784-789
    • Imudia, A.N.1    Kilburn, B.A.2    Petkova, A.3    Edwin, S.S.4    Romero, R.5    Armant, D.R.6
  • 25
    • 0030026954 scopus 로고    scopus 로고
    • Hypoxia alters early gestation human cytotrophoblast differentiation/ invasion in vitro and models the placental defects that occur in preeclampsia
    • Genbacev O, Joslin R, Damsky CH, Polliotti BM, Fisher SJ. Hypoxia alters early gestation human cytotrophoblast differentiation/invasion in vitro and models the placental defects that occur in preeclampsia. J Clin Invest 1996; 97:540-550. (Pubitemid 26039422)
    • (1996) Journal of Clinical Investigation , vol.97 , Issue.2 , pp. 540-550
    • Genbacev, O.1    Joslin, R.2    Damsky, C.H.3    Polliotti, B.M.4    Fisher, S.J.5
  • 26
    • 0030879909 scopus 로고    scopus 로고
    • Regulation of human placental development by oxygen tension
    • Genbacev O, Zhou Y, Ludlow JW, Fisher SJ. Regulation of human placental development by oxygen tension. Science 1997; 277:1669-1672.
    • (1997) Science , vol.277 , pp. 1669-1672
    • Genbacev, O.1    Zhou, Y.2    Ludlow, J.W.3    Fisher, S.J.4
  • 28
    • 0032983892 scopus 로고    scopus 로고
    • Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wall
    • DiFederico E, Genbacev O, Fisher SJ. Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wall. Am J Pathol 1999; 155:293-301. (Pubitemid 29318727)
    • (1999) American Journal of Pathology , vol.155 , Issue.1 , pp. 293-301
    • DiFederico, E.1    Genbacev, O.2    Fisher, S.J.3
  • 29
    • 0015484546 scopus 로고
    • The role of the spiral arteries in the pathogenesis of preeclampsia
    • Brosens IA, Robertson WB, Dixon HG. The role of the spiral arteries in the pathogenesis of preeclampsia. Obstet Gynecol Annu 1972; 1:177-191.
    • (1972) Obstet Gynecol Annu , vol.1 , pp. 177-191
    • Brosens, I.A.1    Robertson, W.B.2    Dixon, H.G.3
  • 30
    • 0036153117 scopus 로고    scopus 로고
    • Increased apoptosis in the syncytiotrophoblast in human term placentas complicated by either preeclampsia or intrauterine growth retardation
    • Ishihara N, Matsuo H, Murakoshi H, Laoag-Fernandez JB, Samoto T, Maruo T. Increased apoptosis in the syncytiotrophoblast in human term placentas complicated by either preeclampsia or intrauterine growth retardation. Am J Obstet Gynecol 2002; 186:158-166.
    • (2002) Am J Obstet Gynecol , vol.186 , pp. 158-166
    • Ishihara, N.1    Matsuo, H.2    Murakoshi, H.3    Laoag-Fernandez, J.B.4    Samoto, T.5    Maruo, T.6
  • 31
    • 0022514874 scopus 로고
    • Inadequate maternal vascular response to placentation in pregnancies complicated by preeclampsia and by small-for-gestational age infants
    • Khong TY, De Wolf F, Robertson WB, Brosens I. Inadequate maternal vascular response to placentation in pregnancies complicated by preeclampsia and by small-for-gestational age infants. Br J Obstet Gynaecol 1986; 93:1049-1059.
    • (1986) Br J Obstet Gynaecol , vol.93 , pp. 1049-1059
    • Khong, T.Y.1    De Wolf, F.2    Robertson, W.B.3    Brosens, I.4
  • 32
    • 33749479262 scopus 로고    scopus 로고
    • Hypoxia and reoxygenation: A possible mechanism for placental oxidative stress in preeclampsia
    • Hung TH, Burton GJ. Hypoxia and reoxygenation: a possible mechanism for placental oxidative stress in preeclampsia. Taiwan J Obstet Gynecol 2006; 45:189-200. (Pubitemid 44519397)
    • (2006) Taiwanese Journal of Obstetrics and Gynecology , vol.45 , Issue.3 , pp. 189-200
    • Hung, T.-H.1    Burton, G.J.2
  • 36
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)- 8-phenyl-4H-1-benzopyran-4-one (LY294002)
    • Vlahos CJ, Matter WF, Hui KY, Brown RF. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 1994; 269:5241-5248. (Pubitemid 24239518)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.7 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, W.F.2    Hui, K.Y.3    Brown, R.F.4
  • 40
    • 0028860250 scopus 로고
    • Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity
    • Mitamura T, Higashiyama S, Taniguchi N, Klagsbrun M, Mekada E. Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity. J Biol Chem 1995; 270:1015-1019.
    • (1995) J Biol Chem , vol.270 , pp. 1015-1019
    • Mitamura, T.1    Higashiyama, S.2    Taniguchi, N.3    Klagsbrun, M.4    Mekada, E.5
  • 42
    • 0034004672 scopus 로고    scopus 로고
    • Extracellular matrix composition and hypoxia regulate the expression of HLA-G and integrins in a human trophoblast cell line
    • Kilburn BA, Wang J, Duniec-Dmuchowski ZM, Leach RE, Romero R, Armant DR. Extracellular matrix composition and hypoxia regulate the expression of HLA-G and integrins in a human trophoblast cell line. Biol Reprod 2000; 62:739-747. (Pubitemid 30118317)
    • (2000) Biology of Reproduction , vol.62 , Issue.3 , pp. 739-747
    • Kilburn, B.A.1    Wang, J.2    Duniec-Dmuchkowski, Z.M.3    Leach, R.E.4    Romero, R.5    Armant, D.R.6
  • 43
    • 34250879580 scopus 로고    scopus 로고
    • Epidermal growth factor-like growth factors prevent apoptosis of alcohol-exposed human placental cytotrophoblast cells
    • Wolff GS, Chiang PJ, Smith SM, Romero R, Armant DR. Epidermal growth factor-like growth factors prevent apoptosis of alcohol-exposed human placental cytotrophoblast cells. Biol Reprod 2007; 77:53-60.
    • (2007) Biol Reprod , vol.77 , pp. 53-60
    • Wolff, G.S.1    Chiang, P.J.2    Smith, S.M.3    Romero, R.4    Armant, D.R.5
  • 44
    • 33745022334 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor (HB-EGF) may improve embryonic development and implantation by increasing vitronectin receptor (integrin alphanubeta3) expression in peri-implantation mouse embryos
    • Lim JJ, Lee DR, Song HS, Kim KS, Yoon TK, Gye MC, Kim MK. Heparin-binding epidermal growth factor (HB-EGF) may improve embryonic development and implantation by increasing vitronectin receptor (integrin alphanubeta3) expression in peri-implantation mouse embryos. J Assist Reprod Genet 2006; 23:111-119.
    • (2006) J Assist Reprod Genet , vol.23 , pp. 111-119
    • Lim, J.J.1    Lee, D.R.2    Song, H.S.3    Kim, K.S.4    Yoon, T.K.5    Gye, M.C.6    Kim, M.K.7
  • 45
    • 0141818170 scopus 로고    scopus 로고
    • Factors regulating trophoblast migration and invasiveness: Possible derangements contributing to pre-eclampsia and fetal injury
    • Lala PK, Chakraborty C. Factors regulating trophoblast migration and invasiveness: possible derangements contributing to pre-eclampsia and fetal injury. Placenta 2003; 24:575-587.
    • (2003) Placenta , vol.24 , pp. 575-587
    • Lala, P.K.1    Chakraborty, C.2
  • 46
    • 0242418203 scopus 로고    scopus 로고
    • Noncatalytic domain of uPA stimulates human extravillous trophoblast migration by using phospholipase C, phosphatidylinositol 3-kinase and mitogen-activated protein kinase
    • Liu J, Chakraborty C, Graham CH, Barbin YP, Dixon SJ, Lala PK. Noncatalytic domain of uPA stimulates human extravillous trophoblast migration by using phospholipase C, phosphatidylinositol 3-kinase and mitogen-activated protein kinase. Exp Cell Res 2003; 286:138-151.
    • (2003) Exp Cell Res , vol.286 , pp. 138-151
    • Liu, J.1    Chakraborty, C.2    Graham, C.H.3    Barbin, Y.P.4    Dixon, S.J.5    Lala, P.K.6
  • 47
    • 0034885755 scopus 로고    scopus 로고
    • Stimulation of human extravillous trophoblast migration by IGF-II is mediated by IGF type 2 receptor involving inhibitory G protein(s) and phosphorylation of MAPK
    • McKinnon T, Chakraborty C, Gleeson LM, Chidiac P, Lala PK. Stimulation of human extravillous trophoblast migration by IGF-II is mediated by IGF type 2 receptor involving inhibitory G protein(s) and phosphorylation of MAPK. J Clin Endocrinol Metab 2001; 86:3665-3674.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3665-3674
    • McKinnon, T.1    Chakraborty, C.2    Gleeson, L.M.3    Chidiac, P.4    Lala, P.K.5
  • 48
    • 0034971842 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein 1 stimulates human trophoblast migration by signaling through alpha 5 beta 1 integrin via mitogen-activated protein kinase pathway
    • Gleeson LM, Chakraborty C, McKinnon T, Lala PK. Insulin-like growth factor-binding protein 1 stimulates human trophoblast migration by signaling through alpha 5 beta 1 integrin via mitogen-activated protein kinase pathway. J Clin Endocrinol Metab 2001; 86:2484-2493.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2484-2493
    • Gleeson, L.M.1    Chakraborty, C.2    McKinnon, T.3    Lala, P.K.4
  • 50
    • 20844455123 scopus 로고    scopus 로고
    • Tumor necrosis factor and vascular endothelial growth factor induce endothelial integrin repertories, regulating endovascular differentiation and apoptosis in a human extravillous trophoblast cell line
    • Fukushima K, Miyamoto S, Tsukimori K, Kobayashi H, Seki H, Takeda S, Kensuke E, Ohtani K, Shibuya M, Nakano H. Tumor necrosis factor and vascular endothelial growth factor induce endothelial integrin repertories, regulating endovascular differentiation and apoptosis in a human extravillous trophoblast cell line. Biol Reprod 2005; 73:172-179.
    • (2005) Biol Reprod , vol.73 , pp. 172-179
    • Fukushima, K.1    Miyamoto, S.2    Tsukimori, K.3    Kobayashi, H.4    Seki, H.5    Takeda, S.6    Kensuke, E.7    Ohtani, K.8    Shibuya, M.9    Nakano, H.10
  • 51
    • 0037471183 scopus 로고    scopus 로고
    • Endothelin-1 promotes migration and induces elevation of [Ca2+]i and phosphorylation of MAP kinase of a human extravillous trophoblast cell line
    • Chakraborty C, Barbin YP, Chakrabarti S, Chidiac P, Dixon SJ, Lala PK. Endothelin-1 promotes migration and induces elevation of [Ca2+]i and phosphorylation of MAP kinase of a human extravillous trophoblast cell line. Mol Cell Endocrinol 2003; 201:63-73.
    • (2003) Mol Cell Endocrinol , vol.201 , pp. 63-73
    • Chakraborty, C.1    Barbin, Y.P.2    Chakrabarti, S.3    Chidiac, P.4    Dixon, S.J.5    Lala, P.K.6
  • 52
    • 4544271532 scopus 로고    scopus 로고
    • EGF-induced trophoblast secretion of MMP-9 and TIMP-1 involves activation of both PI3K and MAPK signalling pathways
    • Qiu Q, Yang M, Tsang BK, Gruslin A. EGF-induced trophoblast secretion of MMP-9 and TIMP-1 involves activation of both PI3K and MAPK signalling pathways. Reproduction 2004; 128:355-363.
    • (2004) Reproduction , vol.128 , pp. 355-363
    • Qiu, Q.1    Yang, M.2    Tsang, B.K.3    Gruslin, A.4
  • 53
    • 5044246271 scopus 로고    scopus 로고
    • Both mitogen-activated protein kinase and phosphatidylinositol 3-kinase signalling are required in epidermal growth factor-induced human trophoblast migration
    • Qiu Q, Yang M, Tsang BK, Gruslin A. Both mitogen-activated protein kinase and phosphatidylinositol 3-kinase signalling are required in epidermal growth factor-induced human trophoblast migration. Mol Hum Reprod 2004; 10:677-684.
    • (2004) Mol Hum Reprod , vol.10 , pp. 677-684
    • Qiu, Q.1    Yang, M.2    Tsang, B.K.3    Gruslin, A.4
  • 54
    • 47649102592 scopus 로고    scopus 로고
    • Epidermal growth factor-stimulated extravillous cytotrophoblast motility is mediated by the activation of PI3-K, Akt and both p38 and p42/44 mitogen-activated protein kinases
    • LaMarca HL, Dash PR, Vishnuthevan K, Harvey E, Sullivan DE, Morris CA, Whitley GS. Epidermal growth factor-stimulated extravillous cytotrophoblast motility is mediated by the activation of PI3-K, Akt and both p38 and p42/44 mitogen-activated protein kinases. Hum Reprod 2008; 23:1733-1741.
    • (2008) Hum Reprod , vol.23 , pp. 1733-1741
    • LaMarca, H.L.1    Dash, P.R.2    Vishnuthevan, K.3    Harvey, E.4    Sullivan, D.E.5    Morris, C.A.6    Whitley, G.S.7
  • 55
    • 34250879075 scopus 로고    scopus 로고
    • Nuclear factor-kappa B, p38, and stress-activated protein kinase mitogen-activated protein kinase signaling pathways regulate proinflammatory cytokines and apoptosis in human placental explants in response to oxidative stress: Effects of antioxidant vitamins
    • Cindrova-Davies T, Spasic-Boskovic O, Jauniaux E, Charnock-Jones DS, Burton GJ. Nuclear factor-kappa B, p38, and stress-activated protein kinase mitogen-activated protein kinase signaling pathways regulate proinflammatory cytokines and apoptosis in human placental explants in response to oxidative stress: effects of antioxidant vitamins. Am J Pathol 2007; 170:1511-1520.
    • (2007) Am J Pathol , vol.170 , pp. 1511-1520
    • Cindrova-Davies, T.1    Spasic-Boskovic, O.2    Jauniaux, E.3    Charnock-Jones, D.S.4    Burton, G.J.5
  • 56
    • 60249102684 scopus 로고    scopus 로고
    • Gabor Than Award Lecture 2008: Pre-eclampsia - From placental oxidative stress to maternal endothelial dysfunction
    • Cindrova-Davies T. Gabor Than Award Lecture 2008: pre-eclampsia - from placental oxidative stress to maternal endothelial dysfunction. Placenta 2009; 30(suppl A):S55-S65.
    • (2009) Placenta , vol.30 , Issue.SUPPL. A
    • Cindrova-Davies, T.1
  • 57
    • 38449119035 scopus 로고    scopus 로고
    • Use of hyperosmolar stress to measure stress-activated protein kinase activation and function in human HTR cells and mouse trophoblast stem cells
    • Zhong W, Xie Y, Wang Y, Lewis J, Trostinskaia A, Wang F, Puscheck EE, Rappolee DA. Use of hyperosmolar stress to measure stress-activated protein kinase activation and function in human HTR cells and mouse trophoblast stem cells. Reprod Sci 2007; 14:534-547.
    • (2007) Reprod Sci , vol.14 , pp. 534-547
    • Zhong, W.1    Xie, Y.2    Wang, Y.3    Lewis, J.4    Trostinskaia, A.5    Wang, F.6    Puscheck, E.E.7    Rappolee, D.A.8
  • 58
    • 58649121074 scopus 로고    scopus 로고
    • Does altered oxygenation or reactive oxygen species alter cell turnover of BeWo choriocarcinoma cells?
    • Heazell AE, Taylor NN, Greenwood SL, Baker PN, Crocker IP. Does altered oxygenation or reactive oxygen species alter cell turnover of BeWo choriocarcinoma cells? Reprod Biomed Online 2009; 18:111-119.
    • (2009) Reprod Biomed Online , vol.18 , pp. 111-119
    • Heazell, A.E.1    Taylor, N.N.2    Greenwood, S.L.3    Baker, P.N.4    Crocker, I.P.5
  • 59
    • 50049101154 scopus 로고    scopus 로고
    • Live and let die - Regulation of villous trophoblast apoptosis in normal and abnormal pregnancies
    • Heazell AE, Crocker IP. Live and let die - regulation of villous trophoblast apoptosis in normal and abnormal pregnancies. Placenta 2008; 29:772-783.
    • (2008) Placenta , vol.29 , pp. 772-783
    • Heazell, A.E.1    Crocker, I.P.2
  • 60
    • 0031914271 scopus 로고    scopus 로고
    • p53, p21, Rb and mdm2 oncoproteins: Expression in normal placenta, partial and complete mole, and choriocarcinoma
    • Fulop V, Mok SC, Genest DR, Gati I, Doszpod J, Berkowitz RS. p53, p21, Rb and mdm2 oncoproteins: expression in normal placenta, partial and complete mole, and choriocarcinoma. J Reprod Med 1998; 43:119-127.
    • (1998) J Reprod Med , vol.43 , pp. 119-127
    • Fulop, V.1    Mok, S.C.2    Genest, D.R.3    Gati, I.4    Doszpod, J.5    Berkowitz, R.S.6
  • 61
    • 0028871189 scopus 로고
    • Expression of the p53 tumour suppressor gene in human placenta: An immunohistochemical study
    • Marzusch K, Ruck P, Horny HP, Dietl J, Kaiserling E. Expression of the p53 tumour suppressor gene in human placenta: an immunohistochemical study. Placenta 1995; 16:101-104.
    • (1995) Placenta , vol.16 , pp. 101-104
    • Marzusch, K.1    Ruck, P.2    Horny, H.P.3    Dietl, J.4    Kaiserling, E.5
  • 63
    • 34547134197 scopus 로고    scopus 로고
    • Epidermal growth factor rescues trophoblast apoptosis induced by reactive oxygen species
    • Moll SJ, Jones CJ, Crocker IP, Baker PN, Heazell AE. Epidermal growth factor rescues trophoblast apoptosis induced by reactive oxygen species. Apoptosis 2007; 12:1611-1622.
    • (2007) Apoptosis , vol.12 , pp. 1611-1622
    • Moll, S.J.1    Jones, C.J.2    Crocker, I.P.3    Baker, P.N.4    Heazell, A.E.5
  • 64
    • 0032966742 scopus 로고    scopus 로고
    • The role of Bcl-2 expression in EGF inhibition of TNF-alpha/IFN- gammainduced villous trophoblast apoptosis
    • Ho S, Winkler-Lowen B, Morrish DW, Dakour J, Li H, Guilbert LJ. The role of Bcl-2 expression in EGF inhibition of TNF-alpha/IFN-gammainduced villous trophoblast apoptosis. Placenta 1999; 20:423-430.
    • (1999) Placenta , vol.20 , pp. 423-430
    • Ho, S.1    Winkler-Lowen, B.2    Morrish, D.W.3    Dakour, J.4    Li, H.5    Guilbert, L.J.6
  • 65
    • 0033059341 scopus 로고    scopus 로고
    • Epidermal growth factor inhibits ceramide-induced apoptosis and lowers ceramide levels in primary placental trophoblasts
    • Payne SG, Brindley DN, Guilbert LJ. Epidermal growth factor inhibits ceramide-induced apoptosis and lowers ceramide levels in primary placental trophoblasts. J Cell Physiol 1999; 180:263-270.
    • (1999) J Cell Physiol , vol.180 , pp. 263-270
    • Payne, S.G.1    Brindley, D.N.2    Guilbert, L.J.3
  • 67
    • 58249136153 scopus 로고    scopus 로고
    • Distinct intracellular signaling pathways control the synthesis of IL-8 and RANTES in TLR1/TLR2, TLR3 or NOD1 activated human airway epithelial cells
    • Berube J, Bourdon C, Yao Y, Rousseau S. Distinct intracellular signaling pathways control the synthesis of IL-8 and RANTES in TLR1/TLR2, TLR3 or NOD1 activated human airway epithelial cells. Cell Signal 2009; 21:448-456.
    • (2009) Cell Signal , vol.21 , pp. 448-456
    • Berube, J.1    Bourdon, C.2    Yao, Y.3    Rousseau, S.4
  • 68
    • 70350213114 scopus 로고    scopus 로고
    • Liver X receptor agonist GW3965 dose-dependently regulates lps-mediated liver injury and modulates posttranscriptional TNF-alpha production and p38 mitogen-activated protein kinase activation in liver macrophages
    • Wang YY, Dahle MK, Steffensen KR, Reinholt FP, Collins JL, Thiemermann C, Aasen AO, Gustafsson JA, Wang JE. Liver X receptor agonist GW3965 dose-dependently regulates lps-mediated liver injury and modulates posttranscriptional TNF-alpha production and p38 mitogen-activated protein kinase activation in liver macrophages. Shock 2009; 32:548-553.
    • (2009) Shock , vol.32 , pp. 548-553
    • Wang, Y.Y.1    Dahle, M.K.2    Steffensen, K.R.3    Reinholt, F.P.4    Collins, J.L.5    Thiemermann, C.6    Aasen, A.O.7    Gustafsson, J.A.8    Wang, J.E.9
  • 69
    • 68049103023 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases are involved in tumor necrosis factor alpha production in macrophages infected with Orientia tsutsugamushi
    • Yun JH, Koo JE, Koh YS. Mitogen-activated protein kinases are involved in tumor necrosis factor alpha production in macrophages infected with Orientia tsutsugamushi. Microbiol Immunol 2009; 53:349-355.
    • (2009) Microbiol Immunol , vol.53 , pp. 349-355
    • Yun, J.H.1    Koo, J.E.2    Koh, Y.S.3
  • 70
    • 38349114778 scopus 로고    scopus 로고
    • p38alpha stabilizes interleukin-6 mRNA via multiple AU-rich elements
    • Zhao W, Liu M, Kirkwood KL. p38alpha stabilizes interleukin-6 mRNA via multiple AU-rich elements. J Biol Chem 2008; 283:1778-1785.
    • (2008) J Biol Chem , vol.283 , pp. 1778-1785
    • Zhao, W.1    Liu, M.2    Kirkwood, K.L.3
  • 71
    • 41749106219 scopus 로고    scopus 로고
    • Ultraviolet radiation (UVR) activates p38 MAP kinase and induces post-transcriptional stabilization of the C/EBPdelta mRNA in G0 growth arrested mammary epithelial cells
    • Li B, Si J, DeWille JW. Ultraviolet radiation (UVR) activates p38 MAP kinase and induces post-transcriptional stabilization of the C/EBPdelta mRNA in G0 growth arrested mammary epithelial cells. J Cell Biochem 2008; 103:1657-1669.
    • (2008) J Cell Biochem , vol.103 , pp. 1657-1669
    • Li, B.1    Si, J.2    DeWille, J.W.3
  • 72
    • 70649112286 scopus 로고    scopus 로고
    • Rapid 3D radiofrequency field mapping using catalyzed double-angle method
    • Wang D, Zuehlsdorff S, Larson AC. Rapid 3D radiofrequency field mapping using catalyzed double-angle method. NMR Biomed 2009; 22: 882-890.
    • (2009) NMR Biomed , vol.22 , pp. 882-890
    • Wang, D.1    Zuehlsdorff, S.2    Larson, A.C.3
  • 73
    • 33644851212 scopus 로고    scopus 로고
    • Transcriptional and posttranscriptional regulation of angiopoietin-2 expression mediated by IGF and PDGF in vascular smooth muscle cells
    • Phelps ED, Updike DL, Bullen EC, Grammas P, Howard EW. Transcriptional and posttranscriptional regulation of angiopoietin-2 expression mediated by IGF and PDGF in vascular smooth muscle cells. Am J Physiol Cell Physiol 2006; 290:C352-C361.
    • (2006) Am J Physiol Cell Physiol , vol.290
    • Phelps, E.D.1    Updike, D.L.2    Bullen, E.C.3    Grammas, P.4    Howard, E.W.5
  • 74
    • 38449102040 scopus 로고    scopus 로고
    • EGF upregulates Na+/H+ exchanger NHE1 by post-translational regulation that is important for cervical cancer cell invasiveness
    • Chiang Y, Chou CY, Hsu KF, Huang YF, Shen MR. EGF upregulates Na+/H+ exchanger NHE1 by post-translational regulation that is important for cervical cancer cell invasiveness. J Cell Physiol 2008; 214:810-819.
    • (2008) J Cell Physiol , vol.214 , pp. 810-819
    • Chiang, Y.1    Chou, C.Y.2    Hsu, K.F.3    Huang, Y.F.4    Shen, M.R.5
  • 75
    • 34249745222 scopus 로고    scopus 로고
    • Insulin-like growth factor-I induces cyclooxygenase-2 expression via PI3K, MAPK and PKC signaling pathways in human ovarian cancer cells
    • Cao Z, Liu LZ, Dixon DA, Zheng JZ, Chandran B, Jiang BH. Insulin-like growth factor-I induces cyclooxygenase-2 expression via PI3K, MAPK and PKC signaling pathways in human ovarian cancer cells. Cell Signal 2007; 19:1542-1553.
    • (2007) Cell Signal , vol.19 , pp. 1542-1553
    • Cao, Z.1    Liu, L.Z.2    Dixon, D.A.3    Zheng, J.Z.4    Chandran, B.5    Jiang, B.H.6
  • 76
    • 33644768174 scopus 로고    scopus 로고
    • Control of translation and mRNA degradation by miRNAs and siRNAs
    • Valencia-Sanchez MA, Liu J, Hannon GJ, Parker R. Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev 2006; 20: 515-524.
    • (2006) Genes Dev , vol.20 , pp. 515-524
    • Valencia-Sanchez, M.A.1    Liu, J.2    Hannon, G.J.3    Parker, R.4
  • 77
    • 34147116217 scopus 로고    scopus 로고
    • The expression of Argonaute2 and related microRNA biogenesis proteins in normal and hypoxic trophoblasts
    • Donker RB, Mouillet JF, Nelson DM, Sadovsky Y. The expression of Argonaute2 and related microRNA biogenesis proteins in normal and hypoxic trophoblasts. Mol Hum Reprod 2007; 13:273-279.
    • (2007) Mol Hum Reprod , vol.13 , pp. 273-279
    • Donker, R.B.1    Mouillet, J.F.2    Nelson, D.M.3    Sadovsky, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.