Human trophoblast survival at low oxygen concentrations requires metalloproteinase-mediated shedding of heparin-binding EGF-like growth factor

Development

Volumn 133, Issue 4, 2006, Pages 751-759

  Armant, D Randall ^a   Kilburn, Brian A ^a   Petkova, Anelia ^a   Edwin, Samuel S ^b   Duniec Dmuchowski, Zophia M ^a   Edwards, Holly J ^a   Romero, Roberto ^b   Leach, Richard E ^c  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c UNIVERSITY OF ILLINOIS   (United States)

Author keywords

Apoptosis; HBEGF (HB EGF); Human; Metalloproteinases; Oxygen; Placenta; Pregnancy; Trophoblast

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 4; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MESSENGER RNA; METALLOPROTEINASE; METALLOPROTEINASE INHIBITOR; OXYGEN;

APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CELL CULTURE; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; CYTOTROPHOBLAST; DOWN REGULATION; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PARACRINE SIGNALING; POSITIVE FEEDBACK; PREECLAMPSIA; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 33645047167     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.02237     Document Type: Article

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