Inhibition of proliferation, migration and tube formation of choroidal microvascular endothelial cells by targeting HIF-1α with short hairpin RNA-expressing plasmid DNA in human RPE cells in a coculture system

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 246, Issue 10, 2008, Pages 1413-1422

  Zhao, Wei ^a   Wang, Yu Sheng ^a   Hui, Yan Nian ^a   Zhu, Jie ^a   Zhang, Peng ^a   Li, Xia ^a   Dou, Guo Rui ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Choroidal microvascular endothelial cell; Choroidal neovascularization; Growth factors; Retinal pigment epithelium

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; PLASMID DNA; SHORT HAIRPIN RNA; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CHOROIDAL MICROVASCULAR ENDOTHELIAL CELL; COCULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE FUNCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; PATHOGENESIS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SUBRETINAL NEOVASCULARIZATION; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; CELL MOVEMENT; CELL PROLIFERATION; CHOROID; CHOROIDAL NEOVASCULARIZATION; COCULTURE TECHNIQUES; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE SILENCING; GENE TARGETING; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; PLASMIDS; RETINAL PIGMENT EPITHELIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, MESSENGER; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 51649127447     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00417-008-0858-8     Document Type: Article

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