From the thymus to longevity in the periphery

Current Opinion in Immunology

Volumn 22, Issue 3, 2010, Pages 274-278

  Wakim, Linda M ^a   Bevan, Michael J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INHIBITOR OF DIFFERENTIATION 2; INTERLEUKIN 12; INTERLEUKIN 15 RECEPTOR; INTERLEUKIN 7 RECEPTOR; INTRINSIC FACTOR; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR T BET;

ADAPTIVE IMMUNITY; CD8+ T LYMPHOCYTE; CELL FATE; CELL FUNCTION; CELL PROLIFERATION; HUMAN; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOID PROGENITOR CELL; MEMORY T LYMPHOCYTE; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMUS; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; MOUSE;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; HUMANS; IMMUNOLOGIC MEMORY; LYMPHOCYTE ACTIVATION; MICE; THYMUS GLAND;

EID: 77953538990     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coi.2010.03.003     Document Type: Review

References (47)

1. Hale J.S., Boursalian T.E., Turk G.L., Fink P.J. Thymic output in aged mice. Proc Natl Acad Sci U S A 2006, 103:8447-8452.
2. Boyman O., Purton J.F., Surh C.D., Sprent J. Cytokines and T-cell homeostasis. Curr Opin Immunol 2007, 19:320-326.
3. Link A., Vogt T.K., Favre S., Britschgi M.R., Acha-Orbea H., Hinz B., Cyster J.G., Luther S.A. Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells. Nat Immunol 2007, 8:1255-1265.
4. Wherry E.J., Puorro K.A., Porgador A., Eisenlohr L.C. The induction of virus-specific CTL as a function of increasing epitope expression: responses rise steadily until excessively high levels of epitope are attained. J Immunol 1999, 163:3735-3745.
5. + T cell response. J Exp Med 2006, 203:2135-2143.
6. Zehn D., Lee S.Y., Bevan M.J. Complete but curtailed T-cell response to very low-affinity antigen. Nature 2009, 458:211-214.
7. Malherbe L., Mark L., Fazilleau N., McHeyzer-Williams L.J., McHeyzer-Williams M.G. Vaccine adjuvants alter TCR-based selection thresholds. Immunity 2008, 28:698-709.
8. Turner S.J., La Gruta N.L., Kedzierska K., Thomas P.G., Doherty P.C. Functional implications of T cell receptor diversity. Curr Opin Immunol 2009, 21:286-290.
9. Kedzierska K., La Gruta N.L., Stambas J., Turner S.J., Doherty P.C. Tracking phenotypically and functionally distinct T cell subsets via T cell repertoire diversity. Mol Immunol 2008, 45:607-618.
10. Badovinac V.P., Porter B.B., Harty J.T. Programmed contraction of CD8(+) T cells after infection. Nat Immunol 2002, 3:619-626.
11. Blattman J.N., Grayson J.M., Wherry E.J., Kaech S.M., Smith K.A., Ahmed R. Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo. Nat Med 2003, 9:540-547.
12. + T cell contraction during primary infection. J Immunol 2006, 176:507-515.
13. + T cell subsets. Immunity 2009, 31:811-822.
14. + T cell differentiation during viral infection. Immunity 2007, 27:393-405.
15. + T cell contraction. Proc Natl Acad Sci U S A 2008, 105:16689-16694.
16. Sallusto F., Lenig D., Forster R., Lipp M., Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999, 401:708-712.
17. Masopust D., Vezys V., Marzo A.L., Lefrancois L. Preferential localization of effector memory cells in nonlymphoid tissue. Science 2001, 291:2413-2417.
18. + T cells. Proc Natl Acad Sci U S A 2001, 98:6313-6318.
19. Gebhardt T., Wakim L.M., Eidsmo L., Reading P.C., Heath W.R., Carbone F.R. Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus. Nat Immunol 2009, 10:524-530.
20. + T cells are selectively activated and retained in latently infected sensory ganglia. Immunity 2003, 18:593-603.
21. + T cells accumulate near sensory nerve endings in genital skin during subclinical HSV-2 reactivation. J Exp Med 2007, 204:595-603.
22. Ray S.J., Franki S.N., Pierce R.H., Dimitrova S., Koteliansky V., Sprague A.G., Doherty P.C., de Fougerolles A.R., Topham D.J. The collagen binding alpha1beta1 integrin VLA-1 regulates CD8 T cell-mediated immune protection against heterologous influenza infection. Immunity 2004, 20:167-179.
23. Hikono H., Kohlmeier J.E., Ely K.H., Scott I., Roberts A.D., Blackman M.A., Woodland D.L. T-cell memory and recall responses to respiratory virus infections. Immunol Rev 2006, 211:119-132.
24. Wakim L.M., Waithman J., van Rooijen N., Heath W.R., Carbone F.R. Dendritic cell-induced memory T cell activation in nonlymphoid tissues. Science 2008, 319:198-202.
25. + memory stem cells. Nat Med 2009, 15:808-813.
26. + T cells survives cytotoxic chemotherapy. Immunity 2009, 31:834-844.
27. + T cell function by the transcription factor Eomesodermin. Science 2003, 302:1041-1043.
28. + T cell fate coupled by T-bet and eomesodermin. Nat Immunol 2005, 6:1236-1244.
29. Joshi N.S., Cui W., Chandele A., Lee H.K., Urso D.R., Hagman J., Gapin L., Kaech S.M. Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity 2007, 27:281-295.
30. + T cell differentiation. J Immunol 2006, 177:7515-7519.
31. + T cell immunity. Nat Immunol 2006, 7:1317-1325.
32. Kallies A., Hawkins E.D., Belz G.T., Metcalf D., Hommel M., Corcoran L.M., Hodgkin P.D., Nutt S.L. Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance. Nat Immunol 2006, 7:466-474.
33. Martins G.A., Cimmino L., Shapiro-Shelef M., Szabolcs M., Herron A., Magnusdottir E., Calame K. Transcriptional repressor Blimp-1 regulates T cell homeostasis and function. Nat Immunol 2006, 7:457-465.
34. Rutishauser R.L., Martins G.A., Kalachikov S., Chandele A., Parish I.A., Meffre E., Jacob J., Calame K., Kaech S.M. Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties. Immunity 2009, 31:296-308.
35. Kallies A., Xin A., Belz G.T., Nutt S.L. Blimp-1 transcription factor is required for the differentiation of effector CD8(+) T cells and memory responses. Immunity 2009, 31:283-295.
36. + T cell precursor can develop into diverse effector and memory subsets. Immunity 2007, 27:985-997.
37. Chang J.T., Palanivel V.R., Kinjyo I., Schambach F., Intlekofer A.M., Banerjee A., Longworth S.A., Vinup K.E., Mrass P., Oliaro J., et al. Asymmetric T lymphocyte division in the initiation of adaptive immune responses. Science 2007, 315:1687-1691.
38. + memory versus effector development. Science 2009, 323:502-505.
39. Wherry E.J., Teichgraber V., Becker T.C., Masopust D., Kaech S.M., Antia R., von Andrian U.H., Ahmed R. Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat Immunol 2003, 4:225-234.
40. + T cells that had developed an effector phenotype. Science 2009, 323:505-509.
41. Harrington L.E., Janowski K.M., Oliver J.R., Zajac A.J., Weaver C.T. Memory CD4 T cells emerge from effector T-cell progenitors. Nature 2008, 452:356-360.
42. + T cells. Proc Natl Acad Sci U S A 2008, 105:18484-18489.
43. + T cells generated during homeostatic proliferation defer to antigen-experienced memory cells. J Immunol 2009, 183:3364-3372.
44. Selin L.K., Vergilis K., Welsh R.M., Nahill S.R. Reduction of otherwise remarkably stable virus-specific cytotoxic T lymphocyte memory by heterologous viral infections. J Exp Med 1996, 183:2489-2499.
45. Selin L.K., Lin M.Y., Kraemer K.A., Pardoll D.M., Schneck J.P., Varga S.M., Santolucito P.A., Pinto A.K., Welsh R.M. Attrition of T cell memory: selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses. Immunity 1999, 11:733-742.
46. Vezys V., Yates A., Casey K.A., Lanier G., Ahmed R., Antia R., Masopust D. Memory CD8 T-cell compartment grows in size with immunological experience. Nature 2009, 457:196-199.
47. Huster K.M., Stemberger C., Gasteiger G., Kastenmuller W., Drexler I., Busch D.H. Cutting edge: memory CD8 T cell compartment grows in size with immunological experience but nevertheless can lose function. J Immunol 2009, 183:6898-6902.