Cytokines and T-cell homeostasis

Current Opinion in Immunology

Volumn 19, Issue 3, 2007, Pages 320-326

  Boyman, Onur ^a   Purton, Jared F ^b   Surh, Charles D ^b   Sprent, Jonathan ^c  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 7; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA;

CD4+ T LYMPHOCYTE; CELL MATURATION; CELL PROLIFERATION; CELL SURVIVAL; HOMEOSTASIS; REVIEW; T LYMPHOCYTE;

ANIMALS; CELL PROLIFERATION; CYTOKINES; HOMEOSTASIS; HUMANS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 34247551647     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coi.2007.04.015     Document Type: Review

References (55)

1. Sprent J., and Surh C.D. T cell memory. Annu Rev Immunol 20 (2002) 551-579
2. Stockinger B., Kassiotis G., and Bourgeois C. Homeostasis and T cell regulation. Curr Opin Immunol 16 (2004) 775-779
3. Jameson S.C. T cell homeostasis: keeping useful T cells alive and live T cells useful. Semin Immunol 17 (2005) 231-237
4. Almeida A.R., Rocha B., Freitas A.A., and Tanchot C. Homeostasis of T cell numbers: from thymus production to peripheral compartmentalization and the indexation of regulatory T cells. Semin Immunol 17 (2005) 239-249
5. Surh C.D., Boyman O., Purton J.F., and Sprent J. Homeostasis of memory T cells. Immunol Rev 211 (2006) 154-163
6. + cells also applies to IL-4-anti-IL-4 mAb complexes.
7. Kamimura D., Sawa Y., Sato M., Agung E., Hirano T., and Murakami M. IL-2 in vivo activities and antitumor efficacy enhanced by an anti-IL-2 mAb. J Immunol 177 (2006) 306-314
8. Boyman O., Surh C.D., and Sprent J. Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease. Expert Opin Biol Ther 6 (2006) 1001-1009
9. + T cells in a manner dependent on IL-4. Int Immunol 18 (2006) 1397-1404
10. + T cells for optimal responses upon secondary antigen encounter.
11. Spierings D.C., Lemmens E.E., Grewal K., Schoenberger S.P., and Green D.R. Duration of CTL activation regulates IL-2 production required for autonomous clonal expansion. Eur J Immunol 36 (2006) 1707-1717
12. + T cells via antigen cross-presentation. J Immunol 176 (2006) 7288-7300
13. Northrop J.K., Thomas R.M., Wells A.D., and Shen H. Epigenetic remodeling of the IL-2 and IFN-γ loci in memory CD8 T cells is influenced by CD4 T cells. J Immunol 177 (2006) 1062-1069
14. + T cells independently of its effects on survival and proliferation. J Immunol 175 (2005) 8003-8010
15. Park J.H., Yu Q., Erman B., Appelbaum J.S., Montoya-Durango D., Grimes H.L., and Singer A. Suppression of IL7Rα transcription by IL-7 and other prosurvival cytokines: a novel mechanism for maximizing IL-7-dependent T cell survival. Immunity 21 (2004) 289-302
16. Klonowski K.D., Williams K.J., Marzo A.L., and Lefrancois L. Cutting edge: IL-7-independent regulation of IL-7 receptor α expression and memory CD8 T cell development. J Immunol 177 (2006) 4247-4251
17. + T cell differentiation. J Immunol 177 (2006) 7515-7519
18. + memory cell pool. J Clin Invest 115 (2005) 1177-1187
19. Sun J.C., Lehar S.M., and Bevan M.J. Augmented IL-7 signaling during viral infection drives greater expansion of effector T cells but does not enhance memory. J Immunol 177 (2006) 4458-4463
20. Becker T.C., Coley S.M., Wherry E.J., and Ahmed R. Bone marrow is a preferred site for homeostatic proliferation of memory CD8 T cells. J Immunol 174 (2005) 1269-1273
21. Parretta E., Cassese G., Barba P., Santoni A., Guardiola J., and Di Rosa F. CD8 cell division maintaining cytotoxic memory occurs predominantly in the bone marrow. J Immunol 174 (2005) 7654-7664
22. + T cell contraction during primary infection. J Immunol 176 (2006) 507-515
23. + T cell expansion and function. J Exp Med 201 (2005) 139-148
24. Pulle G., Vidric M., and Watts T.H. IL-15-dependent induction of 4-1BB promotes antigen-independent CD8 memory T cell survival. J Immunol 176 (2006) 2739-2748
25. + T cells in response to self antigens and IL-15.
26. Ramanathan S., Gagnon J., Leblanc C., Rottapel R., and Ilangumaran S. Suppressor of cytokine signaling 1 stringently regulates distinct functions of IL-7 and IL-15 in vivo during T lymphocyte development and homeostasis. J Immunol 176 (2006) 4029-4041
27. + cells. J Exp Med 203 (2006) 1817-1825
28. + and NK cells, and thereby determine IL-15 responsiveness and consequently homeostatic proliferation and survival of these cells.
29. + cells to undergo optimal expansion, effector functions and memory formation.
30. Valenzuela J.O., Hammerbeck C.D., and Mescher M.F. Cutting edge: Bcl-3 up-regulation by signal 3 cytokine (IL-12) prolongs survival of antigen-activated CD8 T cells. J Immunol 174 (2005) 600-604
31. + T cell responses require STAT4. J Immunol 177 (2006) 7618-7625
32. Chang J., Cho J.H., Lee S.W., Choi S.Y., Ha S.J., and Sung Y.C. IL-12 priming during in vitro antigenic stimulation changes properties of CD8 T cells and increases generation of effector and memory cells. J Immunol 172 (2004) 2818-2826
33. Kolumam G.A., Thomas S., Thompson L.J., Sprent J., and Murali-Krishna K. Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection. J Exp Med 202 (2005) 637-650
34. + T cell response during cross-priming. J Immunol 176 (2006) 4682-4689
35. Thompson L.J., Kolumam G.A., Thomas S., and Murali-Krishna K. Innate inflammatory signals induced by various pathogens differentially dictate the IFN-I dependence of CD8 T cells for clonal expansion and memory formation. J Immunol 177 (2006) 1746-1754
36. Bahl K., Kim S.K., Calcagno C., Ghersi D., Puzone R., Celada F., Selin L.K., and Welsh R.M. IFN-induced attrition of CD8 T cells in the presence or absence of cognate antigen during the early stages of viral infections. J Immunol 176 (2006) 4284-4295
37. + T cells to increase their abundance during virus infection. J Exp Med 201 (2005) 1053-1059
38. + Tregs.
39. Foulds K.E., Rotte M.J., and Seder R.A. IL-10 is required for optimal CD8 T cell memory following Listeria monocytogenes infection. J Immunol 177 (2006) 2565-2574
40. + T cell primary responses and inhibition of secondary responses. J Immunol 174 (2005) 5382-5389
41. + T cells.
42. Ejrnaes M., Filippi C.M., Martinic M.M., Ling E.M., Togher L.M., Crotty S., and von Herrath M.G. Resolution of a chronic viral infection after interleukin-10 receptor blockade. J Exp Med 203 (2006) 2461-2472
43. Malek T.R., and Bayer A.L. Tolerance, not immunity, crucially depends on IL-2. Nat Rev Immunol 4 (2004) 665-674
44. + T cells endowed with proliferative capacity. J Exp Med 198 (2003) 1909-1922
45. Harari A., Dutoit V., Cellerai C., Bart P.A., Du Pasquier R.A., and Pantaleo G. Functional signatures of protective antiviral T-cell immunity in human virus infections. Immunol Rev 211 (2006) 236-254
46. Blattman J.N., Grayson J.M., Wherry E.J., Kaech S.M., Smith K.A., and Ahmed R. Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo. Nat Med 9 (2003) 540-547
47. Villinger F., Miller R., Mori K., Mayne A.E., Bostik P., Sundstrom J.B., Sugimoto C., and Ansari A.A. IL-15 is superior to IL-2 in the generation of long-lived antigen specific memory CD4 and CD8 T cells in rhesus macaques. Vaccine 22 (2004) 3510-3521
48. + T cell memory. Proc Natl Acad Sci USA 101 (2004) 9357-9362
49. Rubinstein M.P., Kovar M., Purton J.F., Cho J.H., Boyman O., Surh C.D., and Sprent J. Converting IL-15 to a superagonist by binding to soluble IL-15Rα. Proc Natl Acad Sci USA 103 (2006) 9166-9171
50. Stoklasek T.A., Schluns K.S., and Lefrancois L. Combined IL-15/IL-15Rα immunotherapy maximizes IL-15 activity in vivo. J Immunol 177 (2006) 6072-6080
51. + memory T cells are long lived. Immunol Rev 211 (2006) 49-57
52. Bourgeois C., Kassiotis G., and Stockinger B. A major role for memory CD4 T cells in the control of lymphopenia-induced proliferation of naïve CD4 T cells. J Immunol 174 (2005) 5316-5323
53. Havenar-Daughton C., Kolumam G.A., and Murali-Krishna K. Cutting edge: the direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection. J Immunol 176 (2006) 3315-3319
54. + Th cells. J Exp Med 200 (2004) 247-253
55. + T cell responses. J Immunol 175 (2005) 5624-5628