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Volumn 41, Issue 3, 2010, Pages 182-189

Elevated Serum Level of IL-23 Correlates with Expression of VEGF in Human Colorectal Carcinoma

Author keywords

Colorectal carcinoma.; IL 23; P53; VEGF

Indexed keywords

INTERLEUKIN 23; PROTEIN P53; VASCULOTROPIN;

EID: 77953522676     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arcmed.2010.02.009     Document Type: Article
Times cited : (32)

References (61)
  • 1
    • 0034758573 scopus 로고    scopus 로고
    • Intratumoural hypoxia resulting in the presence of a fibrotic focus is an independent predictor of early distant relapse in lymph nodenegative breast cancer patients
    • Colpaert C., Vermulen P., van Beest P., et al. Intratumoural hypoxia resulting in the presence of a fibrotic focus is an independent predictor of early distant relapse in lymph nodenegative breast cancer patients. Histopathology 2001, 39:416-425.
    • (2001) Histopathology , vol.39 , pp. 416-425
    • Colpaert, C.1    Vermulen, P.2    van Beest, P.3
  • 2
    • 0036467638 scopus 로고    scopus 로고
    • Tumour hypoxia has independent predictor impact only in patients with node negative cervix cancer
    • Fyles A., Milosevic M., Hedley D., et al. Tumour hypoxia has independent predictor impact only in patients with node negative cervix cancer. J Clin Oncol 2002, 20:680-687.
    • (2002) J Clin Oncol , vol.20 , pp. 680-687
    • Fyles, A.1    Milosevic, M.2    Hedley, D.3
  • 3
    • 54049122927 scopus 로고    scopus 로고
    • The role of hypoxia in recurrence following resection of Dukes' B colorectal cancer
    • Rajaganeshan R., Prasad R., Guillou P.J., et al. The role of hypoxia in recurrence following resection of Dukes' B colorectal cancer. Int J Colorectal Dis 2008, 23:1049-1055.
    • (2008) Int J Colorectal Dis , vol.23 , pp. 1049-1055
    • Rajaganeshan, R.1    Prasad, R.2    Guillou, P.J.3
  • 4
    • 34249978402 scopus 로고    scopus 로고
    • Clinicopathological significance and linkage of HIF-1 alpha and GLUT-1 distributions in human primary colorectal cancers
    • Wincewicz A., Sulkowska M., Koda M., et al. Clinicopathological significance and linkage of HIF-1 alpha and GLUT-1 distributions in human primary colorectal cancers. Pathol Oncol Res 2007, 13:15-20.
    • (2007) Pathol Oncol Res , vol.13 , pp. 15-20
    • Wincewicz, A.1    Sulkowska, M.2    Koda, M.3
  • 5
    • 0033867776 scopus 로고    scopus 로고
    • Hypoxia modulated gene expression: angiogenesis, metastasis and therapeutic exploitation
    • Dachs G.U., Tozer G.M. Hypoxia modulated gene expression: angiogenesis, metastasis and therapeutic exploitation. Eur J Cancer 2000, 36:1649-1660.
    • (2000) Eur J Cancer , vol.36 , pp. 1649-1660
    • Dachs, G.U.1    Tozer, G.M.2
  • 6
    • 27944490875 scopus 로고    scopus 로고
    • VEGF as a therapeutic target in cancer
    • Ferrara N. VEGF as a therapeutic target in cancer. Oncology 2005, 69(suppl 3):11-16.
    • (2005) Oncology , vol.69 , Issue.3 SUPPL. , pp. 11-16
    • Ferrara, N.1
  • 7
    • 24744438663 scopus 로고    scopus 로고
    • Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells
    • Mizukami Y., Jo W.S., Duerr E.M., et al. Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells. Nat Med 2005, 11:992-997.
    • (2005) Nat Med , vol.11 , pp. 992-997
    • Mizukami, Y.1    Jo, W.S.2    Duerr, E.M.3
  • 8
    • 47949096781 scopus 로고    scopus 로고
    • Cancer-related inflammation
    • Mantovani A., Allavena P., Sica A., et al. Cancer-related inflammation. Nature 2008, 454:436-444.
    • (2008) Nature , vol.454 , pp. 436-444
    • Mantovani, A.1    Allavena, P.2    Sica, A.3
  • 9
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens L.M., Werb Z. Inflammation and cancer. Nature 2002, 420:860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 10
    • 34848893583 scopus 로고    scopus 로고
    • Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study
    • Gupta R.B., Harpaz N., Itzkowitz S., et al. Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study. Gastroenterology 2007, 133:1099-1105.
    • (2007) Gastroenterology , vol.133 , pp. 1099-1105
    • Gupta, R.B.1    Harpaz, N.2    Itzkowitz, S.3
  • 11
    • 10744221150 scopus 로고    scopus 로고
    • Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis
    • Rutter M., Saunders B., Wilkinson K., et al. Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis. Gastroenterology 2004, 126:451-459.
    • (2004) Gastroenterology , vol.126 , pp. 451-459
    • Rutter, M.1    Saunders, B.2    Wilkinson, K.3
  • 12
    • 9644291539 scopus 로고    scopus 로고
    • IL-12 and IL-23: master regulators of innate and adaptive immunity
    • Langrish C.L., McKenzie B.S., Wilson N.J., et al. IL-12 and IL-23: master regulators of innate and adaptive immunity. Immunol Rev 2004, 202:96-105.
    • (2004) Immunol Rev , vol.202 , pp. 96-105
    • Langrish, C.L.1    McKenzie, B.S.2    Wilson, N.J.3
  • 13
    • 33646397611 scopus 로고    scopus 로고
    • IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
    • Yen D., Cheung J., Scheerens H., et al. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J Clin Invest 2006, 116:1310-1316.
    • (2006) J Clin Invest , vol.116 , pp. 1310-1316
    • Yen, D.1    Cheung, J.2    Scheerens, H.3
  • 14
    • 31544441415 scopus 로고    scopus 로고
    • Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis
    • Matsuki T., Nakae S., Sudo K., et al. Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis. Int Immunol 2006, 18:399-407.
    • (2006) Int Immunol , vol.18 , pp. 399-407
    • Matsuki, T.1    Nakae, S.2    Sudo, K.3
  • 15
    • 0032534730 scopus 로고    scopus 로고
    • IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: roles of IL-6 in the activation and differentiation of autoreactive T cells
    • Samoilova E.B., Horton J.L., Hilliard B., et al. IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: roles of IL-6 in the activation and differentiation of autoreactive T cells. J Immunol 1998, 161:6480-6486.
    • (1998) J Immunol , vol.161 , pp. 6480-6486
    • Samoilova, E.B.1    Horton, J.L.2    Hilliard, B.3
  • 16
    • 44949101395 scopus 로고    scopus 로고
    • Cytokines: from gut inflammation to colorectal cancer
    • Fantini M.C., Pallone F. Cytokines: from gut inflammation to colorectal cancer. Curr Drug Targets 2008, 95:375-380.
    • (2008) Curr Drug Targets , vol.95 , pp. 375-380
    • Fantini, M.C.1    Pallone, F.2
  • 17
    • 69949120571 scopus 로고    scopus 로고
    • A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
    • Wu S., Rhee K.J., Albesiano E., et al. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med 2009, 15:1016-1022.
    • (2009) Nat Med , vol.15 , pp. 1016-1022
    • Wu, S.1    Rhee, K.J.2    Albesiano, E.3
  • 18
    • 33744479688 scopus 로고    scopus 로고
    • Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells
    • Chen Z., Laurence A., Kanno Y., et al. Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells. Proc Natl Acad Sci 2006, 103:8137-8142.
    • (2006) Proc Natl Acad Sci , vol.103 , pp. 8137-8142
    • Chen, Z.1    Laurence, A.2    Kanno, Y.3
  • 19
    • 68249149652 scopus 로고    scopus 로고
    • Expression of p53, VEGF, microvessel density, and cyclin-D1 in noncancerous tissue of inflammatory bowel disease
    • Alkim C., Savas B., Ensari A., et al. Expression of p53, VEGF, microvessel density, and cyclin-D1 in noncancerous tissue of inflammatory bowel disease. Dig Dis Sci 2009, 54:1979-1984.
    • (2009) Dig Dis Sci , vol.54 , pp. 1979-1984
    • Alkim, C.1    Savas, B.2    Ensari, A.3
  • 20
    • 0037340247 scopus 로고    scopus 로고
    • Hypoxia inducible factor 1α and 2α overexpression in inflammatory bowel disease
    • Giatromanolaki A., Sivridis E., Maltezos E., et al. Hypoxia inducible factor 1α and 2α overexpression in inflammatory bowel disease. J Clin Pathol 2003, 56:209-213.
    • (2003) J Clin Pathol , vol.56 , pp. 209-213
    • Giatromanolaki, A.1    Sivridis, E.2    Maltezos, E.3
  • 21
    • 73349128444 scopus 로고    scopus 로고
    • Hypoxia related growth factors and p53 in preoperative sera from patients with colorectal cancer-evaluation of the prognostic significance of these agents
    • Sulkowski S., Wincewicz A., Zalewski B., et al. Hypoxia related growth factors and p53 in preoperative sera from patients with colorectal cancer-evaluation of the prognostic significance of these agents. Clin Chem Lab Med 2009, 47:1439-1445.
    • (2009) Clin Chem Lab Med , vol.47 , pp. 1439-1445
    • Sulkowski, S.1    Wincewicz, A.2    Zalewski, B.3
  • 22
    • 70350516589 scopus 로고    scopus 로고
    • Identification of immunohistochemical prognostic markers for survival after resection of pulmonary metastases from colorectal carcinoma
    • Pfannschmidt J., Bade S., Hoheisel J., et al. Identification of immunohistochemical prognostic markers for survival after resection of pulmonary metastases from colorectal carcinoma. Thorac Cardiovasc Surg 2009, 57:403-408.
    • (2009) Thorac Cardiovasc Surg , vol.57 , pp. 403-408
    • Pfannschmidt, J.1    Bade, S.2    Hoheisel, J.3
  • 23
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H., Fehrenbacher L., Novotny W., et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004, 350:2335-2342.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 24
    • 65749084523 scopus 로고    scopus 로고
    • Common polymorphisms in the vascular endothelial growth factor gene and colorectal cancer development, prognosis, and survival
    • Dassoulas K., Gazouli M., Rizos S., et al. Common polymorphisms in the vascular endothelial growth factor gene and colorectal cancer development, prognosis, and survival. Mol Carcinog 2009, 486:563-569.
    • (2009) Mol Carcinog , vol.486 , pp. 563-569
    • Dassoulas, K.1    Gazouli, M.2    Rizos, S.3
  • 25
    • 70349499022 scopus 로고    scopus 로고
    • The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors
    • Jain L., Vargo C.A., Danesi R., et al. The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors. Mol Cancer Ther 2009, 8:2496-2508.
    • (2009) Mol Cancer Ther , vol.8 , pp. 2496-2508
    • Jain, L.1    Vargo, C.A.2    Danesi, R.3
  • 26
    • 32144464204 scopus 로고    scopus 로고
    • P53 correlates positively with VEGF in preoperative sera of colorectal cancer patients
    • Famulski W., Sulkowska M., Wincewicz A., et al. P53 correlates positively with VEGF in preoperative sera of colorectal cancer patients. Neoplasma 2006, 53:43-48.
    • (2006) Neoplasma , vol.53 , pp. 43-48
    • Famulski, W.1    Sulkowska, M.2    Wincewicz, A.3
  • 27
    • 47249094555 scopus 로고    scopus 로고
    • P73 isoforms affect VEGF, VEGF165b and PEDF expression in human colorectal tumors: VEGF165b downregulation as a marker of poor prognosis
    • Díaz R., Peña C., Silva J., et al. p73 isoforms affect VEGF, VEGF165b and PEDF expression in human colorectal tumors: VEGF165b downregulation as a marker of poor prognosis. Int J Cancer 2008, 123:1060-1067.
    • (2008) Int J Cancer , vol.123 , pp. 1060-1067
    • Díaz, R.1    Peña, C.2    Silva, J.3
  • 28
    • 71949111022 scopus 로고    scopus 로고
    • Relationships of p53 and Bak with EPO and EPOR in human colorectal cancer
    • Baltaziak M., Koda M., Wincewicz A., et al. Relationships of p53 and Bak with EPO and EPOR in human colorectal cancer. Anticancer Res 2009, 29:4151-4156.
    • (2009) Anticancer Res , vol.29 , pp. 4151-4156
    • Baltaziak, M.1    Koda, M.2    Wincewicz, A.3
  • 29
    • 17644394616 scopus 로고    scopus 로고
    • Smoldering and polarized inflammation in the initiation and promotion of malignant disease
    • Balkwill F., Charles K.A., Mantovani A. Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell 2005, 7:211-217.
    • (2005) Cancer Cell , vol.7 , pp. 211-217
    • Balkwill, F.1    Charles, K.A.2    Mantovani, A.3
  • 30
    • 0025083101 scopus 로고
    • Inflammation and cancer: role of phagocyte-generated oxidants in carcinogenesis
    • Gordon L.I., Weitzman S.A. Inflammation and cancer: role of phagocyte-generated oxidants in carcinogenesis. Blood 1990, 76:655-663.
    • (1990) Blood , vol.76 , pp. 655-663
    • Gordon, L.I.1    Weitzman, S.A.2
  • 31
    • 0002880945 scopus 로고    scopus 로고
    • Chronic infection and inflammation lead to mutation and cancer
    • Oxford University Press, New York, J. Parsonnet, S. Horning (Eds.)
    • Christen S., Hagen T.M., Shigenaga M.K., et al. Chronic infection and inflammation lead to mutation and cancer. Microbes and Malignancy: Infection as a Cause of Cancer 1999, 35-88. Oxford University Press, New York. J. Parsonnet, S. Horning (Eds.).
    • (1999) Microbes and Malignancy: Infection as a Cause of Cancer , pp. 35-88
    • Christen, S.1    Hagen, T.M.2    Shigenaga, M.K.3
  • 32
    • 34250026960 scopus 로고    scopus 로고
    • Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice
    • Elson C.O., Cong Y., Weaver C.T., et al. Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice. Gastroenterology 2007, 132:2359-2370.
    • (2007) Gastroenterology , vol.132 , pp. 2359-2370
    • Elson, C.O.1    Cong, Y.2    Weaver, C.T.3
  • 33
    • 33750530394 scopus 로고    scopus 로고
    • IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis
    • Kullberg M.C., Jankovic D., Feng C.G., et al. IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis. J Exp Med 2006, 203:2485-2494.
    • (2006) J Exp Med , vol.203 , pp. 2485-2494
    • Kullberg, M.C.1    Jankovic, D.2    Feng, C.G.3
  • 34
    • 33750505009 scopus 로고    scopus 로고
    • Interleukin-23 drives innate and T cell-mediated intestinal inflammation
    • Hue S., Ahern P., Buonocore S., et al. Interleukin-23 drives innate and T cell-mediated intestinal inflammation. J Exp Med 2006, 203:2473-2483.
    • (2006) J Exp Med , vol.203 , pp. 2473-2483
    • Hue, S.1    Ahern, P.2    Buonocore, S.3
  • 35
    • 33747089041 scopus 로고    scopus 로고
    • Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology
    • Uhlig H.H., McKenzie B.S., Hue S., et al. Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology. Immunity 2006, 25:309-318.
    • (2006) Immunity , vol.25 , pp. 309-318
    • Uhlig, H.H.1    McKenzie, B.S.2    Hue, S.3
  • 36
    • 48849101281 scopus 로고    scopus 로고
    • The prevalence of Th17 cells in patients with gastric cancer
    • Zhang B., Rong G., Wei H., et al. The prevalence of Th17 cells in patients with gastric cancer. Biochem Biophys Res Commun 2008, 26(374):533-537.
    • (2008) Biochem Biophys Res Commun , vol.26 , Issue.374 , pp. 533-537
    • Zhang, B.1    Rong, G.2    Wei, H.3
  • 37
    • 58549095632 scopus 로고    scopus 로고
    • High expression of Foxp3, IL-23p19 and survivin mRNA in colorectal carcinoma
    • Stanilov N., Miteva L., Mintchev N., et al. High expression of Foxp3, IL-23p19 and survivin mRNA in colorectal carcinoma. Int J Colorectal Dis 2009, 24:151-157.
    • (2009) Int J Colorectal Dis , vol.24 , pp. 151-157
    • Stanilov, N.1    Miteva, L.2    Mintchev, N.3
  • 38
    • 75849142549 scopus 로고    scopus 로고
    • Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis
    • Schonthaler H.B., Huggenberger R., Wculek S.K., et al. Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis. Proc Natl Acad Sci 2009, 106:21264-21269.
    • (2009) Proc Natl Acad Sci , vol.106 , pp. 21264-21269
    • Schonthaler, H.B.1    Huggenberger, R.2    Wculek, S.K.3
  • 39
    • 58649119388 scopus 로고    scopus 로고
    • Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment
    • Kortylewski M., Xin H., Kujawski M., et al. Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment. Cancer Cell 2009, 15:114-123.
    • (2009) Cancer Cell , vol.15 , pp. 114-123
    • Kortylewski, M.1    Xin, H.2    Kujawski, M.3
  • 40
    • 0038269009 scopus 로고    scopus 로고
    • Constitutive STAT3 activation in intestinal T cells from patients with Crohn's disease
    • Lovato P., Brender C., Agnholt J., et al. Constitutive STAT3 activation in intestinal T cells from patients with Crohn's disease. J Biol Chem 2003, 278:16777-16781.
    • (2003) J Biol Chem , vol.278 , pp. 16777-16781
    • Lovato, P.1    Brender, C.2    Agnholt, J.3
  • 41
    • 21044452305 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription 3 signaling pathway: an essential mediator of inflammatory bowel disease and other forms of intestinal inflammation
    • Musso A., Dentelli P., Carlino A., et al. Signal transducers and activators of transcription 3 signaling pathway: an essential mediator of inflammatory bowel disease and other forms of intestinal inflammation. Inflamm Bowel Dis 2005, 11:91-98.
    • (2005) Inflamm Bowel Dis , vol.11 , pp. 91-98
    • Musso, A.1    Dentelli, P.2    Carlino, A.3
  • 42
    • 22044437986 scopus 로고    scopus 로고
    • Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth
    • Corvinus F.M., Orth C., Moriggl R., et al. Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth. Neoplasia 2005, 7:545-555.
    • (2005) Neoplasia , vol.7 , pp. 545-555
    • Corvinus, F.M.1    Orth, C.2    Moriggl, R.3
  • 43
    • 0035925098 scopus 로고    scopus 로고
    • Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects
    • Hockel M., Vaupel P. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst 2001, 93:266-276.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 266-276
    • Hockel, M.1    Vaupel, P.2
  • 44
    • 24644457736 scopus 로고    scopus 로고
    • Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways
    • Xu Q., Briggs J., Park S., et al. Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways. Oncogene 2005, 25(24):5552-5560.
    • (2005) Oncogene , vol.25 , Issue.24 , pp. 5552-5560
    • Xu, Q.1    Briggs, J.2    Park, S.3
  • 45
    • 0037081296 scopus 로고    scopus 로고
    • Modulation of signal transducer and activator of transcription 3 activities by p53 tumor suppressor in breast cancer cell
    • Lin J., Jin X., Rothman K., et al. Modulation of signal transducer and activator of transcription 3 activities by p53 tumor suppressor in breast cancer cell. Cancer Res 2002, 62:376-380.
    • (2002) Cancer Res , vol.62 , pp. 376-380
    • Lin, J.1    Jin, X.2    Rothman, K.3
  • 46
    • 85047699773 scopus 로고    scopus 로고
    • P53 regulates Stat3 phosphorylation and DNA binding activity in human prostate cancer cells expressing constitutively active Stat3
    • Lin J., Tang H., Jin X., et al. p53 regulates Stat3 phosphorylation and DNA binding activity in human prostate cancer cells expressing constitutively active Stat3. Oncogene 2002, 21:3082-3088.
    • (2002) Oncogene , vol.21 , pp. 3082-3088
    • Lin, J.1    Tang, H.2    Jin, X.3
  • 47
    • 23844503025 scopus 로고    scopus 로고
    • Role of Stat3 in regulating p53 expression and function
    • Niu G., Wright K.L., Ma Y., et al. Role of Stat3 in regulating p53 expression and function. Mol Cell Biol 2005, 25:7432-7440.
    • (2005) Mol Cell Biol , vol.25 , pp. 7432-7440
    • Niu, G.1    Wright, K.L.2    Ma, Y.3
  • 48
    • 0034021690 scopus 로고    scopus 로고
    • Hypoxia, clonal selection, and the role of HIF-1 in tumor progression
    • Semenza G.L. Hypoxia, clonal selection, and the role of HIF-1 in tumor progression. Crit Rev Biochem Mol Biol 2000, 35(71):103.
    • (2000) Crit Rev Biochem Mol Biol , vol.35 , Issue.71 , pp. 103
    • Semenza, G.L.1
  • 49
    • 0033954247 scopus 로고    scopus 로고
    • Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha
    • Ravi R., Mookerjee B., Bhujwalla Z.M., et al. Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha. Genes Dev 2000, 14:34-44.
    • (2000) Genes Dev , vol.14 , pp. 34-44
    • Ravi, R.1    Mookerjee, B.2    Bhujwalla, Z.M.3
  • 50
    • 0033587146 scopus 로고    scopus 로고
    • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
    • Maxwell P.H., Wiesener M.S., Chang G.W., et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 1999, 399:271-275.
    • (1999) Nature , vol.399 , pp. 271-275
    • Maxwell, P.H.1    Wiesener, M.S.2    Chang, G.W.3
  • 51
    • 0035958932 scopus 로고    scopus 로고
    • The p14ARF tumor suppressor protein facilitates nucleolar sequestration of hypoxia-inducible factor-1α (HIF-1α) and inhibits HIF-1-mediated transcription
    • Fatyol K., Szalay A.A. The p14ARF tumor suppressor protein facilitates nucleolar sequestration of hypoxia-inducible factor-1α (HIF-1α) and inhibits HIF-1-mediated transcription. J Biol Chem 2001, 276:28421-28429.
    • (2001) J Biol Chem , vol.276 , pp. 28421-28429
    • Fatyol, K.1    Szalay, A.A.2
  • 52
    • 0037713738 scopus 로고    scopus 로고
    • Clinical significance of vascular endothelial growth factor expression and neovascularization in colorectal carcinoma
    • Zheng S., Han M.Y., Xiao Z.X., et al. Clinical significance of vascular endothelial growth factor expression and neovascularization in colorectal carcinoma. World J Gastroenterol 2003, 9:1227-1230.
    • (2003) World J Gastroenterol , vol.9 , pp. 1227-1230
    • Zheng, S.1    Han, M.Y.2    Xiao, Z.X.3
  • 53
    • 0037531794 scopus 로고    scopus 로고
    • The angiogenic switch for vascular endothelial growth factor VEGF-A, VEGF-B, VEGF-C and VEGF-D in the adenomacarcinoma sequence during colorectal cancer progression
    • Hanrahan V., Currie M.J., Gunningham S.P., et al. The angiogenic switch for vascular endothelial growth factor VEGF-A, VEGF-B, VEGF-C and VEGF-D in the adenomacarcinoma sequence during colorectal cancer progression. J Pathol 2003, 200:183-194.
    • (2003) J Pathol , vol.200 , pp. 183-194
    • Hanrahan, V.1    Currie, M.J.2    Gunningham, S.P.3
  • 54
    • 0030707635 scopus 로고    scopus 로고
    • Combined analysis of p53 and vascular endothelial growth factor expression in colorectal carcinoma for determination of tumor vascularity and liver metastasis
    • Kang S.M., Maeda K., Onoda N., et al. Combined analysis of p53 and vascular endothelial growth factor expression in colorectal carcinoma for determination of tumor vascularity and liver metastasis. Int J Cancer 1997, 74:502-507.
    • (1997) Int J Cancer , vol.74 , pp. 502-507
    • Kang, S.M.1    Maeda, K.2    Onoda, N.3
  • 55
    • 2442502554 scopus 로고    scopus 로고
    • Correlation of p53 and bcl-2 expression with vascular endothelial growth factor (VEGF), microvessel density (MVD) and clinicopathological features in colon cancer
    • Perrone G., Vincenzib B., Santinib D., et al. Correlation of p53 and bcl-2 expression with vascular endothelial growth factor (VEGF), microvessel density (MVD) and clinicopathological features in colon cancer. Cancer Lett 2004, 208:227-234.
    • (2004) Cancer Lett , vol.208 , pp. 227-234
    • Perrone, G.1    Vincenzib, B.2    Santinib, D.3
  • 56
    • 0029689349 scopus 로고    scopus 로고
    • P53 and prognosis in colorectal cancer
    • Smith D.R., Goh H.S. p53 and prognosis in colorectal cancer. Ann Acad Med Singapore 1996, 25:107-112.
    • (1996) Ann Acad Med Singapore , vol.25 , pp. 107-112
    • Smith, D.R.1    Goh, H.S.2
  • 57
    • 0030791861 scopus 로고    scopus 로고
    • Prognostic significance of Bcl-2 expression and p53 nuclear accumulation in colorectal adenocarcinoma
    • Manne U., Myers R.B., Moron C., et al. Prognostic significance of Bcl-2 expression and p53 nuclear accumulation in colorectal adenocarcinoma. Int J Cancer 1997, 74:346-358.
    • (1997) Int J Cancer , vol.74 , pp. 346-358
    • Manne, U.1    Myers, R.B.2    Moron, C.3
  • 58
    • 0032535093 scopus 로고    scopus 로고
    • Nuclear accumulation of p53 in colorectal adenocarcinoma: prognostic importance differs with race and location of the tumor
    • Manne U., Weiss H.L., Myers R.B., et al. Nuclear accumulation of p53 in colorectal adenocarcinoma: prognostic importance differs with race and location of the tumor. Cancer 1998, 83:2456-2467.
    • (1998) Cancer , vol.83 , pp. 2456-2467
    • Manne, U.1    Weiss, H.L.2    Myers, R.B.3
  • 59
    • 65249100166 scopus 로고    scopus 로고
    • Prognostic significance of p53 codon 72 polymorphism differs with race in colorectal adenocarcinoma
    • Katkoori V.R., Jia X., Shanmugam C., et al. Prognostic significance of p53 codon 72 polymorphism differs with race in colorectal adenocarcinoma. Clin Cancer Res 2009, 15:2406-2416.
    • (2009) Clin Cancer Res , vol.15 , pp. 2406-2416
    • Katkoori, V.R.1    Jia, X.2    Shanmugam, C.3
  • 60
    • 34347352268 scopus 로고    scopus 로고
    • Correlations of proliferation markers, p53 expression and histological findings in colorectal carcinoma
    • Gorgescu C.V., Sâftoiu A., Georgescu C.C., et al. Correlations of proliferation markers, p53 expression and histological findings in colorectal carcinoma. J Gastrointestin Liver Dis 2007, 16:133-139.
    • (2007) J Gastrointestin Liver Dis , vol.16 , pp. 133-139
    • Gorgescu, C.V.1    Sâftoiu, A.2    Georgescu, C.C.3
  • 61
    • 33644810083 scopus 로고    scopus 로고
    • Prognostic significance of bcl-2 and p53 expression in colorectal carcinoma
    • Zhao D.P., Ding X.W., Peng J.P., et al. Prognostic significance of bcl-2 and p53 expression in colorectal carcinoma. J Zhejiang Univ Sci B 2005, 6:1163-1169.
    • (2005) J Zhejiang Univ Sci B , vol.6 , pp. 1163-1169
    • Zhao, D.P.1    Ding, X.W.2    Peng, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.