-
1
-
-
39749110083
-
Small non-coding RNAs in animal development
-
Stefani G, Slack FJ: Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol 2008, 9:219-230.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 219-230
-
-
Stefani, G.1
Slack, F.J.2
-
2
-
-
41349116135
-
The eukaryotic genome as an RNA machine
-
Amaral PP, Dinger ME, Mercer TR, Mattick JS: The eukaryotic genome as an RNA machine. Science 2008, 319:1787-1789.
-
(2008)
Science
, vol.319
, pp. 1787-1789
-
-
Amaral, P.P.1
Dinger, M.E.2
Mercer, T.R.3
Mattick, J.S.4
-
3
-
-
34250305146
-
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
-
Birney E, Stamatoyannopoulos JA, Dutta A, et al.: Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007, 447:799-816.
-
(2007)
Nature
, vol.447
, pp. 799-816
-
-
Birney, E.1
Stamatoyannopoulos, J.A.2
Dutta, A.3
-
4
-
-
24644519490
-
The transcriptional landscape of the mammalian genome
-
Carninci P, Kasukawa T, Katayama S, et al.: The transcriptional landscape of the mammalian genome. Science 2005, 309:1559-1563.
-
(2005)
Science
, vol.309
, pp. 1559-1563
-
-
Carninci, P.1
Kasukawa, T.2
Katayama, S.3
-
5
-
-
0041941514
-
The small RNA profile during Drosophila melanogaster development
-
Aravin AA, Lagos-Quintana M, Yalcin A, et al.: The small RNA profile during Drosophila melanogaster development. Dev Cell 2003, 5:337-350.
-
(2003)
Dev Cell
, vol.5
, pp. 337-350
-
-
Aravin, A.A.1
Lagos-Quintana, M.2
Yalcin, A.3
-
6
-
-
4043072675
-
MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode
-
Chang S, Johnston RJ Jr, Frokjaer-Jensen C, et al.: MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode. Nature 2004, 430:785-789.
-
(2004)
Nature
, vol.430
, pp. 785-789
-
-
Chang, S.1
Johnston Jr., R.J.2
Frokjaer-Jensen, C.3
-
7
-
-
7944232720
-
RNA and microRNAs in fragile X mental retardation
-
Jin P, Alisch RS, Warren ST: RNA and microRNAs in fragile X mental retardation. Nat Cell Biol 2004, 6:1048-1053.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1048-1053
-
-
Jin, P.1
Alisch, R.S.2
Warren, S.T.3
-
9
-
-
58849112575
-
Biogenesis of small RNAs in animals
-
This is an excellent review that highlights detailed biogenesis of various classes of small RNAs
-
Kim VN, Han J, Siomi MC: Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol 2009, 10:126-139. This is an excellent review that highlights detailed biogenesis of various classes of small RNAs.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 126-139
-
-
Kim, V.N.1
Han, J.2
Siomi, M.C.3
-
10
-
-
33745602880
-
Noncoding RNAs in the mammalian central nervous system
-
Cao X, Yeo G, Muotri AR, et al.: Noncoding RNAs in the mammalian central nervous system. Annu Rev Neurosci 2006, 29:77-103.
-
(2006)
Annu Rev Neurosci
, vol.29
, pp. 77-103
-
-
Cao, X.1
Yeo, G.2
Muotri, A.R.3
-
11
-
-
63149101534
-
Small regulatory RNAs in neurodevelopmental disorders
-
Chang S, Wen S, Chen D, Jin P: Small regulatory RNAs in neurodevelopmental disorders. Hum Mol Genet 2009, 18:R18-R26.
-
(2009)
Hum Mol Genet
, vol.18
-
-
Chang, S.1
Wen, S.2
Chen, D.3
Jin, P.4
-
12
-
-
33947390781
-
A slicermediated mechanism for repeat-associated siRNA 5' end formation in Drosophila
-
This study based on D. melanogaster proposed a ping pong pathway for piRNA biogenesis
-
Gunawardane LS, Saito K, Nishida KM, et al.: A slicermediated mechanism for repeat-associated siRNA 5' end formation in Drosophila. Science 2007, 315:1587-1590. This study based on D. melanogaster proposed a ping pong pathway for piRNA biogenesis.
-
(2007)
Science
, vol.315
, pp. 1587-1590
-
-
Gunawardane, L.S.1
Saito, K.2
Nishida, K.M.3
-
13
-
-
35548991887
-
Gene silencing mechanisms mediated by Aubergine piRNA complexes in Drosophila male gonad
-
This study showed that Aubergine in the testes associates with various kinds of piRNAs, particularly suppressor of stellate piRNAs. This complex can silence the stellate transcripts
-
Nishida KM, Saito K, Mori T, et al.: Gene silencing mechanisms mediated by Aubergine piRNA complexes in Drosophila male gonad. RNA 2007, 13:1911-1922. This study showed that Aubergine in the testes associates with various kinds of piRNAs, particularly suppressor of stellate piRNAs. This complex can silence the stellate transcripts.
-
(2007)
RNA
, vol.13
, pp. 1911-1922
-
-
Nishida, K.M.1
Saito, K.2
Mori, T.3
-
14
-
-
13944282215
-
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
-
Lim LP, Lau NC, Garrett-Engele P, et al.: Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 2005, 433:769-773.
-
(2005)
Nature
, vol.433
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
-
15
-
-
6944246368
-
MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression
-
(Published erratum appears in Nat Genet 2004, 36:1238.)
-
Mansfield JH, Harfe BD, Nissen R, et al.: MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nat Genet 2004, 36:1079-1083. (Published erratum appears in Nat Genet 2004, 36:1238.)
-
(2004)
Nat Genet
, vol.36
, pp. 1079-1083
-
-
Mansfield, J.H.1
Harfe, B.D.2
Nissen, R.3
-
16
-
-
2142654329
-
MicroRNA-directed cleavage of HOXB8 mRNA
-
Yekta S, Shih IH, Bartel DP: MicroRNA-directed cleavage of HOXB8 mRNA. Science 2004, 304:594-596.
-
(2004)
Science
, vol.304
, pp. 594-596
-
-
Yekta, S.1
Shih, I.H.2
Bartel, D.P.3
-
17
-
-
0242266620
-
Dicer is essential for mouse development
-
(Published erratum appears in Nat Genet 2003, 35:287.)
-
Bernstein E, Kim SY, Carmell MA, et al.: Dicer is essential for mouse development. Nat Genet 2003, 35:215-217. (Published erratum appears in Nat Genet 2003, 35:287.)
-
(2003)
Nat Genet
, vol.35
, pp. 215-217
-
-
Bernstein, E.1
Kim, S.Y.2
Carmell, M.A.3
-
18
-
-
18244385475
-
MicroRNAs regulate brain morphogenesis in zebrafish
-
Giraldez AJ, Cinalli RM, Glasner ME, et al.: MicroRNAs regulate brain morphogenesis in zebrafish. Science 2005, 308: 833-838.
-
(2005)
Science
, vol.308
, pp. 833-838
-
-
Giraldez, A.J.1
Cinalli, R.M.2
Glasner, M.E.3
-
19
-
-
31144479591
-
A brain-specific microRNA regulates dendritic spine development
-
(Published erratum appears in Nature 2006, 441:902.)
-
Schratt GM, Tuebing F, Nigh EA, et al.: A brain-specific microRNA regulates dendritic spine development. Nature 2006, 439:283-289. (Published erratum appears in Nature 2006, 441:902.)
-
(2006)
Nature
, vol.439
, pp. 283-289
-
-
Schratt, G.M.1
Tuebing, F.2
Nigh, E.A.3
-
20
-
-
30344449514
-
Synaptic protein synthesis associated with memory is regulated by the RISC pathway in Drosophila
-
(Published erratum appears in Cell 2006, 126:812.)
-
Ashraf SI, McLoon AL, Sclarsic SM, Kunes S: Synaptic protein synthesis associated with memory is regulated by the RISC pathway in Drosophila. Cell 2006, 124:191-205. (Published erratum appears in Cell 2006, 126:812.)
-
(2006)
Cell
, vol.124
, pp. 191-205
-
-
Ashraf, S.I.1
McLoon, A.L.2
Sclarsic, S.M.3
Kunes, S.4
-
21
-
-
1642540373
-
Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway
-
Jin P, Zarnescu DC, Ceman S, et al.: Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat Neurosci 2004, 7:113-117.
-
(2004)
Nat Neurosci
, vol.7
, pp. 113-117
-
-
Jin, P.1
Zarnescu, D.C.2
Ceman, S.3
-
22
-
-
2942715357
-
The fragile X-related gene affects the crawling behavior of Drosophila larvae by regulating the mRNA level of the DEG/ENaC protein pickpocket1
-
Xu K, Bogert BA, Li W, et al.: The fragile X-related gene affects the crawling behavior of Drosophila larvae by regulating the mRNA level of the DEG/ENaC protein pickpocket1. Curr Biol 2004, 14:1025-1034.
-
(2004)
Curr Biol
, vol.14
, pp. 1025-1034
-
-
Xu, K.1
Bogert, B.A.2
Li, W.3
-
23
-
-
33845445765
-
Staufen- and FMRPcontaining neuronal RNPs are structurally and functionally related to somatic P bodies
-
Barbee SA, Estes PS, Cziko AM, et al.: Staufen- and FMRPcontaining neuronal RNPs are structurally and functionally related to somatic P bodies. Neuron 2006, 52:997-1009.
-
(2006)
Neuron
, vol.52
, pp. 997-1009
-
-
Barbee, S.A.1
Estes, P.S.2
Cziko, A.M.3
-
24
-
-
23844501276
-
Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent manner
-
Lugli G, Larson J, Martone ME, et al.: Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent manner. J Neurochem 2005, 94:896-905.
-
(2005)
J Neurochem
, vol.94
, pp. 896-905
-
-
Lugli, G.1
Larson, J.2
Martone, M.E.3
-
25
-
-
58149357047
-
The steady-state level of the nervous-system-specific microRNA-124a is regulated by dFMR1 in Drosophila
-
Xu XL, Li Y, Wang F, Gao FB: The steady-state level of the nervous-system-specific microRNA-124a is regulated by dFMR1 in Drosophila. J Neurosci 2008, 28:11883-11889.
-
(2008)
J Neurosci
, vol.28
, pp. 11883-11889
-
-
Xu, X.L.1
Li, Y.2
Wang, F.3
Gao, F.B.4
-
26
-
-
38349006273
-
Argonaute 1 regulates the fate of germline stem cells in Drosophila
-
Yang L, Chen D, Duan R, et al.: Argonaute 1 regulates the fate of germline stem cells in Drosophila. Development 2007, 134:4265-4272.
-
(2007)
Development
, vol.134
, pp. 4265-4272
-
-
Yang, L.1
Chen, D.2
Duan, R.3
-
27
-
-
34547830405
-
Fragile X mental retardation protein modulates the fate of germline stem cells in Drosophila
-
Yang L, Duan R, Chen D, et al.: Fragile X mental retardation protein modulates the fate of germline stem cells in Drosophila. Hum Mol Genet 2007, 16:1814-1820.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 1814-1820
-
-
Yang, L.1
Duan, R.2
Chen, D.3
-
28
-
-
0032830639
-
Rett syndrome is caused by mutations in X-linked MeCP2, encoding methyl-CpGbinding protein 2
-
Amir RE, Van den Veyver IB, Wan M, et al.: Rett syndrome is caused by mutations in X-linked MeCP2, encoding methyl-CpGbinding protein 2. Nat Genet 1999, 23:185-188.
-
(1999)
Nat Genet
, vol.23
, pp. 185-188
-
-
Amir, R.E.1
Van Den Veyver, I.B.2
Wan, M.3
-
29
-
-
0342437491
-
MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin
-
Nan X, Campoy FJ, Bird A: MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell 1997, 88:471-481.
-
(1997)
Cell
, vol.88
, pp. 471-481
-
-
Nan, X.1
Campoy, F.J.2
Bird, A.3
-
30
-
-
45849105557
-
MeCP2, a key contributor to neurological disease, activates and represses transcription
-
Chahrour M, Jung SY, Shaw C, et al.: MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 2008, 320:1224-1229.
-
(2008)
Science
, vol.320
, pp. 1224-1229
-
-
Chahrour, M.1
Jung, S.Y.2
Shaw, C.3
-
31
-
-
28044439909
-
A cAMP-response element binding protein induced microRNA regulates neuronal morphogenesis
-
(Published erratum appears in Proc Natl Acad Sci U S A 2006, 103:825.)
-
Vo N, Klein ME, Varlamova O, et al.: A cAMP-response element binding protein induced microRNA regulates neuronal morphogenesis. Proc Natl Acad Sci U S A 2005, 102:16426-16431. (Published erratum appears in Proc Natl Acad Sci U S A 2006, 103:825.)
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 16426-16431
-
-
Vo, N.1
Klein, M.E.2
Varlamova, O.3
-
32
-
-
36448969801
-
Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA
-
Klein ME, Lioy DT, Ma L, et al.: Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA. Nat Neurosci 2007, 10:1513-1514.
-
(2007)
Nat Neurosci
, vol.10
, pp. 1513-1514
-
-
Klein, M.E.1
Lioy, D.T.2
Ma, L.3
-
33
-
-
41849119117
-
MeCP2-dependent repression of an imprinted miR-184 released by depolarization
-
Nomura T, Kimura M, Horii T, et al.: MeCP2-dependent repression of an imprinted miR-184 released by depolarization. Hum Mol Genet 2008, 17:1192-1199.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 1192-1199
-
-
Nomura, T.1
Kimura, M.2
Horii, T.3
-
34
-
-
12144290440
-
Genetic, developmental, and physical factors associated with attention deficit hyperactivity disorder in patients with velocardiofacial syndrome
-
Gothelf D, Presburger G, Levy D, et al.: Genetic, developmental, and physical factors associated with attention deficit hyperactivity disorder in patients with velocardiofacial syndrome. Am J Med Genet B Neuropsychiatr Genet 2004, 126B:116-121.
-
(2004)
Am J Med Genet B Neuropsychiatr Genet
, vol.126 B
, pp. 116-121
-
-
Gothelf, D.1
Presburger, G.2
Levy, D.3
-
35
-
-
12144289483
-
Obsessive-compulsive disorder in patients with velocardiofacial (22q11 deletion) syndrome
-
Gothelf D, Presburger G, Zohar AH, et al.: Obsessive-compulsive disorder in patients with velocardiofacial (22q11 deletion) syndrome. Am J Med Genet B Neuropsychiatr Genet 2004, 126B:99-105.
-
(2004)
Am J Med Genet B Neuropsychiatr Genet
, vol.126 B
, pp. 99-105
-
-
Gothelf, D.1
Presburger, G.2
Zohar, A.H.3
-
36
-
-
27644478443
-
Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice
-
Paterlini M, Zakharenko SS, Lai WS, et al.: Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice. Nat Neurosci 2005, 8:1586-1594.
-
(2005)
Nat Neurosci
, vol.8
, pp. 1586-1594
-
-
Paterlini, M.1
Zakharenko, S.S.2
Lai, W.S.3
-
37
-
-
43949124669
-
Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model
-
Stark KL, Xu B, Bagchi A, et al.: Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat Genet 2008, 40:751-760.
-
(2008)
Nat Genet
, vol.40
, pp. 751-760
-
-
Stark, K.L.1
Xu, B.2
Bagchi, A.3
-
39
-
-
0037403505
-
Global up-regulation of chromosome 21 gene expression in the developing Down syndrome brain
-
Mao R, Zielke CL, Zielke HR, Pevsner J: Global up-regulation of chromosome 21 gene expression in the developing Down syndrome brain. Genomics 2003, 81:457-467.
-
(2003)
Genomics
, vol.81
, pp. 457-467
-
-
Mao, R.1
Zielke, C.L.2
Zielke, H.R.3
Pevsner, J.4
-
40
-
-
0028341315
-
Down syndrome phenotypes: The consequences of chromosomal imbalance
-
Korenberg JR, Chen XN, Schipper R, et al.: Down syndrome phenotypes: the consequences of chromosomal imbalance. Proc Natl Acad Sci U S A 1994, 91:4997-5001.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4997-5001
-
-
Korenberg, J.R.1
Chen, X.N.2
Schipper, R.3
-
41
-
-
42749095242
-
Human chromosome 21- derived miRNAs are overexpressed in down syndrome brains and hearts
-
Kuhn DE, Nuovo GJ, Martin MM, et al.: Human chromosome 21- derived miRNAs are overexpressed in down syndrome brains and hearts. Biochem Biophys Res Commun 2008, 370:473-477.
-
(2008)
Biochem Biophys Res Commun
, vol.370
, pp. 473-477
-
-
Kuhn, D.E.1
Nuovo, G.J.2
Martin, M.M.3
-
42
-
-
34547727263
-
Human microRNA- 155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3' untranslated region: A mechanism for functional single-nucleotide polymorphisms related to phenotypes
-
Sethupathy P, Borel C, Gagnebin M, et al.: Human microRNA- 155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3' untranslated region: a mechanism for functional single-nucleotide polymorphisms related to phenotypes. Am J Hum Genet 2007, 81:405-413.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 405-413
-
-
Sethupathy, P.1
Borel, C.2
Gagnebin, M.3
-
43
-
-
33745577150
-
A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep
-
Clop A, Marcq F, Takeda H, et al.: A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep. Nat Genet 2006, 38:813-818.
-
(2006)
Nat Genet
, vol.38
, pp. 813-818
-
-
Clop, A.1
Marcq, F.2
Takeda, H.3
-
44
-
-
34250648147
-
Polymorphic microRNAtarget interactions: A novel source of phenotypic variation
-
Georges M, Clop A, Marcq F, et al.: Polymorphic microRNAtarget interactions: a novel source of phenotypic variation. Cold Spring Harb Symp Quant Biol 2006, 71:343-350.
-
(2006)
Cold Spring Harb Symp Quant Biol
, vol.71
, pp. 343-350
-
-
Georges, M.1
Clop, A.2
Marcq, F.3
-
45
-
-
34548822460
-
Drosophila PIWI associates with chromatin and interacts directly with HP1a
-
Brower-Toland B, Findley SD, Jiang L, et al.: Drosophila PIWI associates with chromatin and interacts directly with HP1a. Genes Dev 2007, 21:2300-2311.
-
(2007)
Genes Dev
, vol.21
, pp. 2300-2311
-
-
Brower-Toland, B.1
Findley, S.D.2
Jiang, L.3
-
46
-
-
33644770293
-
RNAi components are required for nuclear clustering of Polycomb group response elements
-
Grimaud C, Bantignies F, Pal-Bhadra M, et al.: RNAi components are required for nuclear clustering of Polycomb group response elements. Cell 2006, 124:957-971.
-
(2006)
Cell
, vol.124
, pp. 957-971
-
-
Grimaud, C.1
Bantignies, F.2
Pal-Bhadra, M.3
-
47
-
-
0942279615
-
Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery
-
Pal-Bhadra M, Leibovitch BA, Gandhi SG, et al.: Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery. Science 2004, 303:669-672.
-
(2004)
Science
, vol.303
, pp. 669-672
-
-
Pal-Bhadra, M.1
Leibovitch, B.A.2
Gandhi, S.G.3
-
48
-
-
36048937264
-
An epigenetic activation role of Piwi and a Piwiassociated piRNA in Drosophila melanogaster
-
Yin H, Lin H: An epigenetic activation role of Piwi and a Piwiassociated piRNA in Drosophila melanogaster. Nature 2007, 450:304-308.
-
(2007)
Nature
, vol.450
, pp. 304-308
-
-
Yin, H.1
Lin, H.2
-
49
-
-
2642531973
-
Epigenetics in human disease and prospects for epigenetic therapy
-
Egger G, Liang G, Aparicio A, Jones PA: Epigenetics in human disease and prospects for epigenetic therapy. Nature 2004, 429:457-463.
-
(2004)
Nature
, vol.429
, pp. 457-463
-
-
Egger, G.1
Liang, G.2
Aparicio, A.3
Jones, P.A.4
-
50
-
-
0035839057
-
The role of DNA methylation in mammalian epigenetics
-
Jones PA, Takai D: The role of DNA methylation in mammalian epigenetics. Science 2001, 293:1068-1070.
-
(2001)
Science
, vol.293
, pp. 1068-1070
-
-
Jones, P.A.1
Takai, D.2
|