-
2
-
-
0019948176
-
Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products
-
Amara SG, Jonas V, Rosenfeld MG, et al. Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products. Nature 1982;298:240-244
-
(1982)
Nature
, vol.298
, pp. 240-244
-
-
Amara, S.G.1
Jonas, V.2
Rosenfeld, M.G.3
-
3
-
-
0029969026
-
Calcitonin gene-related peptide and its receptors: Molecular genetics, physiology, pathophysiology, and therapeutic potentials
-
Wimalawansa SJ. Calcitonin gene-related peptide and its receptors: molecular genetics, physiology, pathophysiology, and therapeutic potentials. Endocr Rev 1996;17:533-585
-
(1996)
Endocr Rev
, vol.17
, pp. 533-585
-
-
Wimalawansa, S.J.1
-
4
-
-
0021838224
-
Calcitonin gene-related peptide is present in mammalian cerebrovascular nerve fibres and dilates pial and peripheral arteries
-
Hanko J, Hardebo JE, Kahrstrom J, et al. Calcitonin gene-related peptide is present in mammalian cerebrovascular nerve fibres and dilates pial and peripheral arteries. Neurosci Lett 1985;57:91-95
-
(1985)
Neurosci Lett
, vol.57
, pp. 91-95
-
-
Hanko, J.1
Hardebo, J.E.2
Kahrstrom, J.3
-
5
-
-
77952933457
-
CGRP, a vasodilator neuropeptide that stimulates neuromuscular transmission and EC coupling
-
Vega AV, Avila G. CGRP, a vasodilator neuropeptide that stimulates neuromuscular transmission and EC coupling. Curr Vasc Pharmacol 2010;8:394-403
-
(2010)
Curr Vasc Pharmacol
, vol.8
, pp. 394-403
-
-
Vega, A.V.1
Avila, G.2
-
6
-
-
0032868529
-
Mice lacking alpha-calcitonin gene-related peptide exhibit normal cardiovascular regulation and neuromuscular development
-
Lu JT, Son YJ, Lee J, et al. Mice lacking alpha-calcitonin gene-related peptide exhibit normal cardiovascular regulation and neuromuscular development. Mol Cell Neurosci 1999;14:99-120
-
(1999)
Mol Cell Neurosci
, vol.14
, pp. 99-120
-
-
Lu, J.T.1
Son, Y.J.2
Lee, J.3
-
7
-
-
0021928959
-
Infusion of a novel peptide, calcitonin gene-related peptide (CGRP) in man. Pharmacokinetics and effects on gastric acid secretion and on gastrointestinal hormones
-
Kraenzlin ME, Ch'ng JL, Mulderry PK, et al. Infusion of a novel peptide, calcitonin gene-related peptide (CGRP) in man. Pharmacokinetics and effects on gastric acid secretion and on gastrointestinal hormones. Regul Pept 1985;10:189-197
-
(1985)
Regul Pept
, vol.10
, pp. 189-197
-
-
Kraenzlin, M.E.1
Ch'Ng, J.L.2
Mulderry, P.K.3
-
8
-
-
15844426346
-
A cDNA encoding the calcitonin gene-related peptide type 1 receptor
-
Aiyar N, Rand K, Elshourbagy NA, et al. A cDNA encoding the calcitonin gene-related peptide type 1 receptor. J Biol Chem 1996;271:11325-11329
-
(1996)
J Biol Chem
, vol.271
, pp. 11325-11329
-
-
Aiyar, N.1
Rand, K.2
Elshourbagy, N.A.3
-
9
-
-
0032574982
-
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
-
McLatchie LM, Fraser NJ, Main MJ, et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature 1998;393:333-339
-
(1998)
Nature
, vol.393
, pp. 333-339
-
-
McLatchie, L.M.1
Fraser, N.J.2
Main, M.J.3
-
10
-
-
0041765735
-
Localization and modulation of calcitonin gene-related peptide-receptor component protein-immunoreactive cells in the rat central and peripheral nervous systems
-
Ma W, Chabot JG, Powell KJ, et al. Localization and modulation of calcitonin gene-related peptide-receptor component protein-immunoreactive cells in the rat central and peripheral nervous systems. Neuroscience 2003;120:677-694
-
(2003)
Neuroscience
, vol.120
, pp. 677-694
-
-
Ma, W.1
Chabot, J.G.2
Powell, K.J.3
-
11
-
-
0032509186
-
Expression of calcitonin receptor-like receptor and receptor-activity- modifying proteins in human cranial arteries
-
Sams A, Jansen-Olesen I. Expression of calcitonin receptor-like receptor and receptor-activity-modifying proteins in human cranial arteries. Neurosci Lett 1998;258:41-44
-
(1998)
Neurosci Lett
, vol.258
, pp. 41-44
-
-
Sams, A.1
Jansen-Olesen, I.2
-
12
-
-
77749255462
-
Refolding and characterization of a soluble ectodomain complex of the calcitonin gene-related peptide receptor
-
Koth CM, Abdul-Manan N, Lepre CA, et al. Refolding and characterization of a soluble ectodomain complex of the calcitonin gene-related peptide receptor. Biochemistry 2010;49:1862-1872
-
(2010)
Biochemistry
, vol.49
, pp. 1862-1872
-
-
Koth, C.M.1
Abdul-Manan, N.2
Lepre, C.A.3
-
13
-
-
72749105799
-
Mapping interaction sites within the N-terminus of the calcitonin gene-related peptide receptor; The role of residues 23-60 of the calcitonin receptor-like receptor
-
Barwell J, Miller PS, Donnelly D, Poyner DR. Mapping interaction sites within the N-terminus of the calcitonin gene-related peptide receptor; the role of residues 23-60 of the calcitonin receptor-like receptor. Peptides 2010;31:170-176
-
(2010)
Peptides
, vol.31
, pp. 170-176
-
-
Barwell, J.1
Miller, P.S.2
Donnelly, D.3
Poyner, D.R.4
-
14
-
-
12244290339
-
Desensitisation of adrenomedullin and CGRP receptors
-
Hay DL, Poyner DR, Smith DM. Desensitisation of adrenomedullin and CGRP receptors. Regul Pept 2003;112:139-145
-
(2003)
Regul Pept
, vol.112
, pp. 139-145
-
-
Hay, D.L.1
Poyner, D.R.2
Smith, D.M.3
-
15
-
-
0000103682
-
The tentorial nerves and localization of intracranial pain in man
-
Feindel W, Penfield W, McNaughton FL. The tentorial nerves and localization of intracranial pain in man. Neurology 1960;10:555-563
-
(1960)
Neurology
, vol.10
, pp. 555-563
-
-
Feindel, W.1
Penfield, W.2
McNaughton, F.L.3
-
16
-
-
0000418174
-
A contribution to the mechanism of intracranial pain
-
Penfield W. A contribution to the mechanism of intracranial pain. Proc Assoc Res Nerv Mental Dis 1934;15:399-415
-
(1934)
Proc Assoc Res Nerv Mental Dis
, vol.15
, pp. 399-415
-
-
Penfield, W.1
-
17
-
-
0001301238
-
Experimental studies on headache: Pain-sensitive structures of the head and their significance in headache
-
Ray BS, Wolff HG. Experimental studies on headache: pain-sensitive structures of the head and their significance in headache. Arch Surg 1940;41:813-856
-
(1940)
Arch Surg
, vol.41
, pp. 813-856
-
-
Ray, B.S.1
Wolff, H.G.2
-
18
-
-
0033036503
-
Messenger molecules and receptor mRNA in the human trigeminal ganglion
-
Tajti J, Uddman R, Moller S, et al. Messenger molecules and receptor mRNA in the human trigeminal ganglion. J Auton Nerv Syst 1999;76:176-183
-
(1999)
J Auton Nerv Syst
, vol.76
, pp. 176-183
-
-
Tajti, J.1
Uddman, R.2
Moller, S.3
-
19
-
-
0022384731
-
Calcitonin gene-related peptide coexists with substance P in capsaicin sensitive neurons and sensory ganglia of the rat
-
Skofitsch G, Jacobowitz DM. Calcitonin gene-related peptide coexists with substance P in capsaicin sensitive neurons and sensory ganglia of the rat. Peptides 1985;6:747-754
-
(1985)
Peptides
, vol.6
, pp. 747-754
-
-
Skofitsch, G.1
Jacobowitz, D.M.2
-
20
-
-
0021914970
-
Coexistence of calcitonin gene-related peptide and substance P-like peptide in single cells of the trigeminal ganglion of the rat: Immunohistochemical analysis
-
Lee Y, Kawai Y, Shiosaka S, et al. Coexistence of calcitonin gene-related peptide and substance P-like peptide in single cells of the trigeminal ganglion of the rat: immunohistochemical analysis. Brain Res 1985;330:194-196
-
(1985)
Brain Res
, vol.330
, pp. 194-196
-
-
Lee, Y.1
Kawai, Y.2
Shiosaka, S.3
-
21
-
-
0027374238
-
Innervation of the dura mater encephali of cat and rat: Ultrastructure and calcitonin gene-related peptide-like and substance P-like immunoreactivity
-
Messlinger K, Hanesch U, Baumgartel M, et al. Innervation of the dura mater encephali of cat and rat: ultrastructure and calcitonin gene-related peptide-like and substance P-like immunoreactivity. Anat Embryol (Berl) 1993;188:219-237
-
(1993)
Anat Embryol (Berl)
, vol.188
, pp. 219-237
-
-
Messlinger, K.1
Hanesch, U.2
Baumgartel, M.3
-
22
-
-
43049178205
-
Central projections of the sensory innervation of the rat middle meningeal artery
-
Liu Y, Broman J, Edvinsson L. Central projections of the sensory innervation of the rat middle meningeal artery. Brain Res 2008;1208:103-110
-
(2008)
Brain Res
, vol.1208
, pp. 103-110
-
-
Liu, Y.1
Broman, J.2
Edvinsson, L.3
-
23
-
-
0021215649
-
Release of the predicted calcitonin gene-related peptide from cultured rat trigeminal ganglion cells
-
Mason RT, Peterfreund RA, Sawchenko PE, et al. Release of the predicted calcitonin gene-related peptide from cultured rat trigeminal ganglion cells. Nature 1984;308:653-655
-
(1984)
Nature
, vol.308
, pp. 653-655
-
-
Mason, R.T.1
Peterfreund, R.A.2
Sawchenko, P.E.3
-
24
-
-
44649144697
-
Calcitonin gene-related peptide release from intact isolated dorsal root and trigeminal ganglia
-
Eberhardt M, Hoffmann T, Sauer SK, et al. Calcitonin gene-related peptide release from intact isolated dorsal root and trigeminal ganglia. Neuropeptides 2008;42:311-317
-
(2008)
Neuropeptides
, vol.42
, pp. 311-317
-
-
Eberhardt, M.1
Hoffmann, T.2
Sauer, S.K.3
-
25
-
-
3543146127
-
Regulation of calcitonin gene-related peptide release from rat trigeminal nucleus caudalis slices in vitro
-
Jenkins DW, Langmead CJ, Parsons AA, Strijbos PJ. Regulation of calcitonin gene-related peptide release from rat trigeminal nucleus caudalis slices in vitro. Neurosci Lett 2004;366:241-244
-
(2004)
Neurosci Lett
, vol.366
, pp. 241-244
-
-
Jenkins, D.W.1
Langmead, C.J.2
Parsons, A.A.3
Strijbos, P.J.4
-
26
-
-
0032910607
-
2 from rat dura mater encephali following electrical and chemical stimulation in vitro
-
DOI 10.1016/S0306-4522(98)00366-2, PII S0306452298003662
-
Ebersberger A, Averbeck B, Messlinger K, Reeh PW. Release of substance P, calcitonin gene-related peptide and prostaglandin E2 from rat dura mater encephali following electrical and chemical stimulation in vitro. Neuroscience 1999;89:901-907 (Pubitemid 29071014)
-
(1999)
Neuroscience
, vol.89
, Issue.3
, pp. 901-907
-
-
Ebersberger, A.1
Averbeck, B.2
Messlinger, K.3
Reeh, P.W.4
-
27
-
-
0036957637
-
Nitric oxide releases calcitonin-gene-related peptide from rat dura mater encephali promoting increases in meningeal blood flow
-
Strecker T, Dux M, Messlinger K. Nitric oxide releases calcitonin-gene-related peptide from rat dura mater encephali promoting increases in meningeal blood flow. J Vasc Res 2002;39:489-496
-
(2002)
J Vasc Res
, vol.39
, pp. 489-496
-
-
Strecker, T.1
Dux, M.2
Messlinger, K.3
-
28
-
-
0036284227
-
ATP can enhance the proton-induced CGRP release through P2Y receptors and secondary PGE(2) release in isolated rat dura mater
-
Zimmermann K, Reeh PW, Averbeck B. ATP can enhance the proton-induced CGRP release through P2Y receptors and secondary PGE(2) release in isolated rat dura mater. Pain 2002;97:259-265
-
(2002)
Pain
, vol.97
, pp. 259-265
-
-
Zimmermann, K.1
Reeh, P.W.2
Averbeck, B.3
-
29
-
-
34247327856
-
Cannabinoid and vanilloid effects of R (+)-methanandamide in the hemisected meningeal preparation
-
Fischer MJ, Messlinger K. Cannabinoid and vanilloid effects of R (+)-methanandamide in the hemisected meningeal preparation. Cephalalgia 2007;27:422-428
-
(2007)
Cephalalgia
, vol.27
, pp. 422-428
-
-
Fischer, M.J.1
Messlinger, K.2
-
30
-
-
0023874663
-
Release of vasoactive peptides in the extracerebral circulation of humans and the cat during activation of the trigeminovascular system
-
Goadsby PJ, Edvinsson L, Ekman R. Release of vasoactive peptides in the extracerebral circulation of humans and the cat during activation of the trigeminovascular system. Ann Neurol 1988;23:193-196
-
(1988)
Ann Neurol
, vol.23
, pp. 193-196
-
-
Goadsby, P.J.1
Edvinsson, L.2
Ekman, R.3
-
31
-
-
67349236616
-
Calcitonin gene-related peptide in blood: Is it increased in the external jugular vein during migraine and cluster headache? A review
-
Tfelt-Hansen P, Le H. Calcitonin gene-related peptide in blood: is it increased in the external jugular vein during migraine and cluster headache? A review. J Headache Pain 2009;10:137-143
-
(2009)
J Headache Pain
, vol.10
, pp. 137-143
-
-
Tfelt-Hansen, P.1
Le, H.2
-
32
-
-
0029759994
-
Calcitonin gene-related peptide is released from capsaicin-sensitive nerve fibres and induces vasodilatation of human cerebral arteries concomitant with activation of adenylyl cyclase
-
Jansen-Olesen I, Mortensen A, Edvinsson L. Calcitonin gene-related peptide is released from capsaicin-sensitive nerve fibres and induces vasodilatation of human cerebral arteries concomitant with activation of adenylyl cyclase. Cephalalgia 1996;16:310-316
-
(1996)
Cephalalgia
, vol.16
, pp. 310-316
-
-
Jansen-Olesen, I.1
Mortensen, A.2
Edvinsson, L.3
-
33
-
-
0344737766
-
NO-induced migraine attack: Strong increase in plasma calcitonin gene-related peptide (CGRP) concentration and negative correlation with platelet serotonin release
-
Juhasz G, Zsombok T, Modos EA, et al. NO-induced migraine attack: strong increase in plasma calcitonin gene-related peptide (CGRP) concentration and negative correlation with platelet serotonin release. Pain 2003;106:461-470
-
(2003)
Pain
, vol.106
, pp. 461-470
-
-
Juhasz, G.1
Zsombok, T.2
Modos, E.A.3
-
34
-
-
70350704554
-
Glyceroltrinitrate facilitates stimulated CGRP release but not gene expression of CGRP or its receptor components in rat trigeminal ganglia
-
Eberhardt M, Neeb L, Vogel EM, et al. Glyceroltrinitrate facilitates stimulated CGRP release but not gene expression of CGRP or its receptor components in rat trigeminal ganglia. Neuropeptides 2009;43:483-489
-
(2009)
Neuropeptides
, vol.43
, pp. 483-489
-
-
Eberhardt, M.1
Neeb, L.2
Vogel, E.M.3
-
35
-
-
33847628339
-
Critical evaluation of the colocalization between calcitonin gene-related peptide, substance P, transient receptor potential vanilloid subfamily type 1 immunoreactivities, and isolectin B4 binding in primary afferent neurons of the rat and mouse
-
Price TJ, Flores CM. Critical evaluation of the colocalization between calcitonin gene-related peptide, substance P, transient receptor potential vanilloid subfamily type 1 immunoreactivities, and isolectin B4 binding in primary afferent neurons of the rat and mouse. J Pain 2007;8:263-272
-
(2007)
J Pain
, vol.8
, pp. 263-272
-
-
Price, T.J.1
Flores, C.M.2
-
36
-
-
0028180003
-
Capsaicin-sensitive' sensory neurons in cluster headache: Pathophysiological aspects and therapeutic indication
-
Fusco BM, Fiore G, Gallo F, et al. 'Capsaicin-sensitive' sensory neurons in cluster headache: pathophysiological aspects and therapeutic indication. Headache 1994;34:132-137
-
(1994)
Headache
, vol.34
, pp. 132-137
-
-
Fusco, B.M.1
Fiore, G.2
Gallo, F.3
-
37
-
-
10044259901
-
Inhibitory effect of BIBN4096BS on cephalic vasodilatation induced by CGRP or transcranial electrical stimulation in the rat
-
Petersen KA, Birk S, Doods H, et al. Inhibitory effect of BIBN4096BS on cephalic vasodilatation induced by CGRP or transcranial electrical stimulation in the rat. Br J Pharmacol 2004;143:697-704
-
(2004)
Br J Pharmacol
, vol.143
, pp. 697-704
-
-
Petersen, K.A.1
Birk, S.2
Doods, H.3
-
38
-
-
0036171973
-
Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model
-
Bolay H, Reuter U, Dunn AK, et al. Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model. Nat Med 2002;8:136-142
-
(2002)
Nat Med
, vol.8
, pp. 136-142
-
-
Bolay, H.1
Reuter, U.2
Dunn, A.K.3
-
39
-
-
0022347682
-
Calcitonin gene-related peptide is a potent inhibitor of substance P degradation
-
Le Greves P, Nyberg F, Terenius L, Hokfelt T. Calcitonin gene-related peptide is a potent inhibitor of substance P degradation. Eur J Pharmacol 1985;115:309-311
-
(1985)
Eur J Pharmacol
, vol.115
, pp. 309-311
-
-
Le Greves, P.1
Nyberg, F.2
Terenius, L.3
Hokfelt, T.4
-
40
-
-
0023143665
-
Calcitonin gene-related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats
-
Oku R, Satoh M, Fujii N, et al. Calcitonin gene-related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats. Brain Res 1987;403:350-354
-
(1987)
Brain Res
, vol.403
, pp. 350-354
-
-
Oku, R.1
Satoh, M.2
Fujii, N.3
-
41
-
-
0026534177
-
Calcitonin gene-related peptide enhances substance P-induced behaviors via metabolic inhibition: In vivo evidence for a new mechanism of neuromodulation
-
Mao J, Coghill RC, Kellstein DE, et al. Calcitonin gene-related peptide enhances substance P-induced behaviors via metabolic inhibition: in vivo evidence for a new mechanism of neuromodulation. Brain Res 1992;574:157-163
-
(1992)
Brain Res
, vol.574
, pp. 157-163
-
-
Mao, J.1
Coghill, R.C.2
Kellstein, D.E.3
-
42
-
-
4143102442
-
Calcitonin gene-related peptide (CGRP) modulates nociceptive trigeminovascular transmission in the cat
-
Storer RJ, Akerman S, Goadsby PJ. Calcitonin gene-related peptide (CGRP) modulates nociceptive trigeminovascular transmission in the cat. Br J Pharmacol 2004;142:1171-1181
-
(2004)
Br J Pharmacol
, vol.142
, pp. 1171-1181
-
-
Storer, R.J.1
Akerman, S.2
Goadsby, P.J.3
-
43
-
-
0025441936
-
Tachykinins and calcitonin gene-related peptide enhance release of endogenous glutamate and aspartate from the rat spinal dorsal horn slice
-
Kangrga I, Randic M. Tachykinins and calcitonin gene-related peptide enhance release of endogenous glutamate and aspartate from the rat spinal dorsal horn slice. J Neurosci 1990;10:2026-2038
-
(1990)
J Neurosci
, vol.10
, pp. 2026-2038
-
-
Kangrga, I.1
Randic, M.2
-
44
-
-
0025894071
-
Effects of prolonged infusion of human alpha calcitonin gene-related peptide on hemodynamics, renal blood flow and hormone levels in congestive heart failure
-
Shekhar YC, Anand IS, Sarma R, et al. Effects of prolonged infusion of human alpha calcitonin gene-related peptide on hemodynamics, renal blood flow and hormone levels in congestive heart failure. Am J Cardiol 1991;67:732-736
-
(1991)
Am J Cardiol
, vol.67
, pp. 732-736
-
-
Shekhar, Y.C.1
Anand, I.S.2
Sarma, R.3
-
46
-
-
67650502716
-
Role of calcitonin gene-related peptide in light-aversive behavior: Implications for migraine
-
Recober A, Kuburas A, Zhang Z, et al. Role of calcitonin gene-related peptide in light-aversive behavior: implications for migraine. J Neurosci 2009;29:8798-8804
-
(2009)
J Neurosci
, vol.29
, pp. 8798-8804
-
-
Recober, A.1
Kuburas, A.2
Zhang, Z.3
-
47
-
-
0024597810
-
Calcitonin gene-related peptide receptor antagonist human CGRP-8-37)
-
Chiba T, Yamaguchi A, Yamatani T, et al. Calcitonin gene-related peptide receptor antagonist human CGRP-(8-37). Am J Physiol 1989;256:E331-3
-
(1989)
Am J Physiol
, vol.256
-
-
Chiba, T.1
Yamaguchi, A.2
Yamatani, T.3
-
48
-
-
0035902440
-
Turn structures in CGRP C-terminal analogues promote stable arrangements of key residue side chains
-
Carpenter KA, Schmidt R, von Mentzer B, et al. Turn structures in CGRP C-terminal analogues promote stable arrangements of key residue side chains. Biochemistry 2001;40:8317-8325
-
(2001)
Biochemistry
, vol.40
, pp. 8317-8325
-
-
Carpenter, K.A.1
Schmidt, R.2
Von Mentzer, B.3
-
49
-
-
33644540743
-
Calcitonin gene-related peptide-induced vasodilation in the human forearm is antagonized by CGRP8-37: Evaluation of a human in vivo pharmacodynamic model
-
Vanmolkot FH, Van der Schueren BJ, de Hoon JN. Calcitonin gene-related peptide-induced vasodilation in the human forearm is antagonized by CGRP8-37: evaluation of a human in vivo pharmacodynamic model. Clin Pharmacol Ther 2006;79:263-273
-
(2006)
Clin Pharmacol Ther
, vol.79
, pp. 263-273
-
-
Vanmolkot, F.H.1
Van Der Schueren, B.J.2
De Hoon, J.N.3
-
50
-
-
58149092957
-
Identification of potent, selective, and metabolically stable peptide antagonists to the calcitonin gene-related peptide (CGRP) receptor
-
Miranda LP, Holder JR, Shi L, et al. Identification of potent, selective, and metabolically stable peptide antagonists to the calcitonin gene-related peptide (CGRP) receptor. J Med Chem 2008;51:7889-7897
-
(2008)
J Med Chem
, vol.51
, pp. 7889-7897
-
-
Miranda, L.P.1
Holder, J.R.2
Shi, L.3
-
51
-
-
0030708674
-
Quinine analogs as non-peptide calcitonin gene-related peptide (CGRP) receptor antagonists
-
Daines RA, Sham KKC, Taggert JJ, et al. Quinine analogs as non-peptide calcitonin gene-related peptide (CGRP) receptor antagonists. Bioorg Med Chem Lett 1997;7:2673-2676
-
(1997)
Bioorg Med Chem Lett
, vol.7
, pp. 2673-2676
-
-
Daines, R.A.1
Sham, K.K.C.2
Taggert, J.J.3
-
52
-
-
0033970471
-
Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist
-
Doods H, Hallermayer G, Wu D, et al. Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist. Br J Pharmacol 2000;129:420-423
-
(2000)
Br J Pharmacol
, vol.129
, pp. 420-423
-
-
Doods, H.1
Hallermayer, G.2
Wu, D.3
-
53
-
-
0035129463
-
Pharmacology of SB-273779, a nonpeptide calcitonin gene-related peptide 1 receptor antagonist
-
Aiyar N, Daines RA, Disa J, et al. Pharmacology of SB-273779, a nonpeptide calcitonin gene-related peptide 1 receptor antagonist. J Pharmacol Exp Ther 2001;296:768-775
-
(2001)
J Pharmacol Exp Ther
, vol.296
, pp. 768-775
-
-
Aiyar, N.1
Daines, R.A.2
Disa, J.3
-
54
-
-
75449111000
-
Potent oxadiazole CGRP receptor antagonists for the potential treatment of migraine
-
Nichols PL, Brand J, Briggs M, et al. Potent oxadiazole CGRP receptor antagonists for the potential treatment of migraine. Bioorg Med Chem Lett 2010;20:1368-1372
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 1368-1372
-
-
Nichols, P.L.1
Brand, J.2
Briggs, M.3
-
55
-
-
0037134498
-
Receptor activity-modifying protein 1 determines the species selectivity of non-peptide CGRP receptor antagonists
-
Mallee JJ, Salvatore CA, LeBourdelles B, et al. Receptor activity-modifying protein 1 determines the species selectivity of non-peptide CGRP receptor antagonists. J Biol Chem 2002;277:14294-14298
-
(2002)
J Biol Chem
, vol.277
, pp. 14294-14298
-
-
Mallee, J.J.1
Salvatore, C.A.2
Lebourdelles, B.3
-
56
-
-
0037216736
-
Investigation of CGRP receptors and peptide pharmacology in human coronary arteries. Characterization with a nonpeptide antagonist
-
Hasbak P, Saetrum OO, Eskesen K, et al. Investigation of CGRP receptors and peptide pharmacology in human coronary arteries. Characterization with a nonpeptide antagonist. J Pharmacol Exp Ther 2003;304:326-333
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 326-333
-
-
Hasbak, P.1
Saetrum, O.O.2
Eskesen, K.3
-
57
-
-
0642334595
-
Short bioactive Spiegelmers to migraine-associated calcitonin gene-related peptide rapidly identified by a novel approach: Tailored-SELEX
-
Vater A, Jarosch F, Buchner K, Klussmann S. Short bioactive Spiegelmers to migraine-associated calcitonin gene-related peptide rapidly identified by a novel approach: tailored-SELEX. Nucleic Acids Res 2003;31:e130
-
(2003)
Nucleic Acids Res
, vol.31
-
-
Vater, A.1
Jarosch, F.2
Buchner, K.3
Klussmann, S.4
-
58
-
-
33745107264
-
Inhibition of stimulated meningeal blood flow by a calcitonin gene-related peptide binding mirror-image RNA oligonucleotide
-
Denekas T, Troltzsch M, Vater A, et al. Inhibition of stimulated meningeal blood flow by a calcitonin gene-related peptide binding mirror-image RNA oligonucleotide. Br J Pharmacol 2006;148:536-543
-
(2006)
Br J Pharmacol
, vol.148
, pp. 536-543
-
-
Denekas, T.1
Troltzsch, M.2
Vater, A.3
-
59
-
-
34249075410
-
Effect of two novel CGRP-binding compounds in a closed cranial window rat model
-
Juhl L, Edvinsson L, Olesen J, Jansen-Olesen I. Effect of two novel CGRP-binding compounds in a closed cranial window rat model. Eur J Pharmacol 2007;567:117-124
-
(2007)
Eur J Pharmacol
, vol.567
, pp. 117-124
-
-
Juhl, L.1
Edvinsson, L.2
Olesen, J.3
Jansen-Olesen, I.4
-
60
-
-
36148978527
-
Potent, orally bioavailable calcitonin gene-related peptide receptor antagonists for the treatment of migraine: Discovery of N-[(3R,6S)-6-2,3- difluorophenyl)-2-oxo-1-2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2, 3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl) piperidine-1-carboxamide (MK-0974)
-
Paone DV, Shaw AW, Nguyen DN, et al. Potent, orally bioavailable calcitonin gene-related peptide receptor antagonists for the treatment of migraine: discovery of N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2- trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl) piperidine-1-carboxamide (MK-0974). J Med Chem 2007;50:5564-5567
-
(2007)
J Med Chem
, vol.50
, pp. 5564-5567
-
-
Paone, D.V.1
Shaw, A.W.2
Nguyen, D.N.3
-
61
-
-
38749114993
-
Pharmacological characterization of MK-0974 [N-[(3R,6S)-6-2,3- difluorophenyl)-2-oxo-1-2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2, 3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide], a potent and orally active calcitonin gene-related peptide receptor antagonist for the treatment of migraine
-
Salvatore CA, Hershey JC, Corcoran HA, et al. Pharmacological characterization of MK-0974 [N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2- trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl) piperidine-1-carboxamide], a potent and orally active calcitonin gene-related peptide receptor antagonist for the treatment of migraine. J Pharmacol Exp Ther 2008;324:416-421
-
(2008)
J Pharmacol Exp Ther
, vol.324
, pp. 416-421
-
-
Salvatore, C.A.1
Hershey, J.C.2
Corcoran, H.A.3
-
62
-
-
67651102827
-
The identification of potent, orally bioavailable tricyclic CGRP receptor antagonists
-
Bell IM, Bednar RA, Corcoran HA, et al. The identification of potent, orally bioavailable tricyclic CGRP receptor antagonists. Bioorg Med Chem Lett 2009;19:4740-4742
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 4740-4742
-
-
Bell, I.M.1
Bednar, R.A.2
Corcoran, H.A.3
-
63
-
-
69949108860
-
Novel CGRP receptor antagonists through a design strategy of target simplification with addition of molecular flexibility
-
Wood MR, Schirripa KM, Kim JJ, et al. Novel CGRP receptor antagonists through a design strategy of target simplification with addition of molecular flexibility. Bioorg Med Chem Lett 2009;19:5787-5790
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 5787-5790
-
-
Wood, M.R.1
Schirripa, K.M.2
Kim, J.J.3
-
64
-
-
57849129258
-
The discovery of highly potent CGRP receptor antagonists
-
Stump CA, Bell IM, Bednar RA, et al. The discovery of highly potent CGRP receptor antagonists. Bioorg Med Chem Lett 2009;19:214-217
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 214-217
-
-
Stump, C.A.1
Bell, I.M.2
Bednar, R.A.3
-
65
-
-
77953425030
-
Discovery of MK-3207: A highly potent, orally bioavailable CGRP receptor antagonist
-
Bell IM, Galliccio SN, Wood MR, et al. Discovery of MK-3207: a highly potent, orally bioavailable CGRP receptor antagonist. ACS Med Chem Lett 2010;1:24-29
-
(2010)
ACS Med Chem Lett
, vol.1
, pp. 24-29
-
-
Bell, I.M.1
Galliccio, S.N.2
Wood, M.R.3
-
66
-
-
77949687406
-
Pharmacological properties of MK-3207 [2-[(8R)-8-(3,-difluorophenyl)-10- oxo-6,9-diazaspiro[4.5]dec-9-yl]-N-[(2R)-2'-ox o-1,1',2',3-tetrahydrospiro [indene-2,3'-pyrrolo[2,3-b]pyridin]-5-yl] acetamide], a potent and orally active CGRP receptor antagonist
-
Salvatore CA, Moore EL, Calamari A, et al. Pharmacological properties of MK-3207 [2-[(8R)-8-(3,-difluorophenyl)-10-oxo-6,9-diazaspiro[4.5]dec-9-yl]-N- [(2R)-2'-ox o-1,1',2',3-tetrahydrospiro [indene-2,3'-pyrrolo[2,3-b]pyridin]-5- yl] acetamide], a potent and orally active CGRP receptor antagonist. J Pharmacol Exp Ther 2010;333:152-160
-
(2010)
J Pharmacol Exp Ther
, vol.333
, pp. 152-160
-
-
Salvatore, C.A.1
Moore, E.L.2
Calamari, A.3
-
67
-
-
50249096199
-
Discovery of (R)-4-(8-fluoro-2-oxo-1,2-dihydroquinazolin-3 (4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl) piperidin-1-yl)propan-2-yl)piperidine-1-carboxami de (BMS-694153): A potent antagonist of the human calcitonin gene-related peptide receptor for migraine with rapid and efficient intranasal exposure
-
Degnan AP, Chaturvedula PV, Conway CM, et al. Discovery of (R)-4-(8-fluoro-2-oxo-1,2-dihydroquinazolin-3 (4H)-yl)-N-(3-(7-methyl-1H- indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl) piperidine-1-carboxami de (BMS-694153): a potent antagonist of the human calcitonin gene-related peptide receptor for migraine with rapid and efficient intranasal exposure. J Med Chem 2008;51:4858-4861
-
(2008)
J Med Chem
, vol.51
, pp. 4858-4861
-
-
Degnan, A.P.1
Chaturvedula, P.V.2
Conway, C.M.3
-
68
-
-
37348999890
-
Clinical pharmacology of the serotonin receptor agonist, zolmitriptan
-
Peterlin BL, Rapoport AM. Clinical pharmacology of the serotonin receptor agonist, zolmitriptan. Expert Opin Drug Metab Toxicol 2007;3:899-911
-
(2007)
Expert Opin Drug Metab Toxicol
, vol.3
, pp. 899-911
-
-
Peterlin, B.L.1
Rapoport, A.M.2
-
69
-
-
33846087513
-
Effectiveness and satisfaction with zolmitriptan 5 mg nasal spray for treatment of migraine in real-life practice: Results of a postmarketing surveillance study
-
Diener HC, Evers S. Effectiveness and satisfaction with zolmitriptan 5 mg nasal spray for treatment of migraine in real-life practice: results of a postmarketing surveillance study. Clin Drug Investig 2007;27:59-66
-
(2007)
Clin Drug Investig
, vol.27
, pp. 59-66
-
-
Diener, H.C.1
Evers, S.2
-
70
-
-
66349123811
-
Carbamates as potent calcitonin gene-related peptide antagonists with improved solution stability
-
Degnan AP, Conway CM, Dalterio RA, et al. Carbamates as potent calcitonin gene-related peptide antagonists with improved solution stability. Bioorg Med Chem Lett 2009;19:3555-3558
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 3555-3558
-
-
Degnan, A.P.1
Conway, C.M.2
Dalterio, R.A.3
-
71
-
-
11844291266
-
Comparison of intravenous valproate with intravenous lysine- acetylsalicylic acid in acute migraine attacks
-
Leniger T, Pageler L, Stude P, et al. Comparison of intravenous valproate with intravenous lysine-acetylsalicylic acid in acute migraine attacks. Headache 2005;45:42-46
-
(2005)
Headache
, vol.45
, pp. 42-46
-
-
Leniger, T.1
Pageler, L.2
Stude, P.3
-
72
-
-
0035340714
-
Neurogenic inflammation in the context of migraine
-
Williamson DJ, Hargreaves RJ. Neurogenic inflammation in the context of migraine. Microsc Res Tech 2001;53:167-178
-
(2001)
Microsc Res Tech
, vol.53
, pp. 167-178
-
-
Williamson, D.J.1
Hargreaves, R.J.2
-
73
-
-
21344470124
-
The nonpeptide calcitonin gene-related peptide receptor antagonist BIBN4096BS lowers the activity of neurons with meningeal input in the rat spinal trigeminal nucleus
-
Fischer MJ, Koulchitsky S, Messlinger K. The nonpeptide calcitonin gene-related peptide receptor antagonist BIBN4096BS lowers the activity of neurons with meningeal input in the rat spinal trigeminal nucleus. J Neurosci 2005;25:5877-5883
-
(2005)
J Neurosci
, vol.25
, pp. 5877-5883
-
-
Fischer, M.J.1
Koulchitsky, S.2
Messlinger, K.3
-
74
-
-
61849148972
-
Calcitonin gene-related peptide receptor inhibition reduces neuronal activity induced by prolonged increase in nitric oxide in the rat spinal trigeminal nucleus
-
Koulchitsky S, Fischer MJ, Messlinger K. Calcitonin gene-related peptide receptor inhibition reduces neuronal activity induced by prolonged increase in nitric oxide in the rat spinal trigeminal nucleus. Cephalalgia 2009;29:408-417
-
(2009)
Cephalalgia
, vol.29
, pp. 408-417
-
-
Koulchitsky, S.1
Fischer, M.J.2
Messlinger, K.3
-
76
-
-
27644461793
-
Calcitonin gene-related peptide does not excite or sensitize meningeal nociceptors: Implications for the pathophysiology of migraine
-
Levy D, Burstein R, Strassman AM. Calcitonin gene-related peptide does not excite or sensitize meningeal nociceptors: implications for the pathophysiology of migraine. Ann Neurol 2005;58:698-705
-
(2005)
Ann Neurol
, vol.58
, pp. 698-705
-
-
Levy, D.1
Burstein, R.2
Strassman, A.M.3
-
77
-
-
70350689543
-
Calcitonin gene-related peptide receptor antagonist olcegepant acts in the spinal trigeminal nucleus
-
Sixt ML, Messlinger K, Fischer MJ. Calcitonin gene-related peptide receptor antagonist olcegepant acts in the spinal trigeminal nucleus. Brain 2009;132:3134-3141
-
(2009)
Brain
, vol.132
, pp. 3134-3141
-
-
Sixt, M.L.1
Messlinger, K.2
Fischer, M.J.3
-
78
-
-
77949716986
-
CSF levels and binding pattern of novel CGRP receptor antagonists in rhesus monkey and human central nervous system: Toward the development of a PET tracer
-
Sur C, Hargreaves R, Bell I, et al. CSF levels and binding pattern of novel CGRP receptor antagonists in rhesus monkey and human central nervous system: toward the development of a PET tracer. Cephalagia 2009;29:136-137
-
(2009)
Cephalagia
, vol.29
, pp. 136-137
-
-
Sur, C.1
Hargreaves, R.2
Bell, I.3
-
79
-
-
77949873859
-
Mapping the CGRP receptor ligand binding domain. tryptophan-84 of RAMP1 is critical for agonist and antagonist binding
-
Moore EL, Gingell JJ, Kane SA, et al. Mapping the CGRP receptor ligand binding domain. tryptophan-84 of RAMP1 is critical for agonist and antagonist binding. Biochem Biophys Res Commun 2010;394:141-145
-
(2010)
Biochem Biophys Res Commun
, vol.394
, pp. 141-145
-
-
Moore, E.L.1
Gingell, J.J.2
Kane, S.A.3
-
80
-
-
72949116357
-
Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74
-
Miller PS, Barwell J, Poyner DR, et al. Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74. Biochem Biophys Res Commun 2010;391:437-442
-
(2010)
Biochem Biophys Res Commun
, vol.391
, pp. 437-442
-
-
Miller, P.S.1
Barwell, J.2
Poyner, D.R.3
-
82
-
-
2942512592
-
Safety, tolerability and pharmacokinetics of BIBN 4096 BS, the first selective small molecule calcitonin gene-related peptide receptor antagonist, following single intravenous administration in healthy volunteers
-
Iovino M, Feifel U, Yong CL, et al. Safety, tolerability and pharmacokinetics of BIBN 4096 BS, the first selective small molecule calcitonin gene-related peptide receptor antagonist, following single intravenous administration in healthy volunteers. Cephalalgia 2004;24:645-656
-
(2004)
Cephalalgia
, vol.24
, pp. 645-656
-
-
Iovino, M.1
Feifel, U.2
Yong, C.L.3
-
83
-
-
13244252481
-
The CGRP-antagonist, BIBN4096BS does not affect cerebral or systemic haemodynamics in healthy volunteers
-
Petersen KA, Birk S, Lassen LH, et al. The CGRP-antagonist, BIBN4096BS does not affect cerebral or systemic haemodynamics in healthy volunteers. Cephalalgia 2005;25:139-147
-
(2005)
Cephalalgia
, vol.25
, pp. 139-147
-
-
Petersen, K.A.1
Birk, S.2
Lassen, L.H.3
-
84
-
-
41149140954
-
Calcitonin gene-related peptide8-37 antagonizes capsaicin-induced vasodilation in the skin: Evaluation of a human in vivo pharmacodynamic model
-
Van der Schueren BJ, Rogiers A, Vanmolkot FH, et al. Calcitonin gene-related peptide8-37 antagonizes capsaicin-induced vasodilation in the skin: evaluation of a human in vivo pharmacodynamic model. J Pharmacol Exp Ther 2008;325:248-255
-
(2008)
J Pharmacol Exp Ther
, vol.325
, pp. 248-255
-
-
Van Der Schueren, B.J.1
Rogiers, A.2
Vanmolkot, F.H.3
-
85
-
-
72949106255
-
Inhibition of capsaicin-induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK-0974)
-
Sinclair SR, Kane SA, Van der Schueren BJ, et al. Inhibition of capsaicin-induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK-0974). Br J Clin Pharmacol 2010;69:15-22
-
(2010)
Br J Clin Pharmacol
, vol.69
, pp. 15-22
-
-
Sinclair, S.R.1
Kane, S.A.2
Van Der Schueren, B.J.3
-
86
-
-
13944253331
-
BIBN4096BS antagonizes human alpha-calcitonin gene related peptide-induced headache and extracerebral artery dilatation
-
Petersen KA, Lassen LH, Birk S, et al. BIBN4096BS antagonizes human alpha-calcitonin gene related peptide-induced headache and extracerebral artery dilatation. Clin Pharmacol Ther 2005;77:202-213
-
(2005)
Clin Pharmacol Ther
, vol.77
, pp. 202-213
-
-
Petersen, K.A.1
Lassen, L.H.2
Birk, S.3
-
87
-
-
1542346238
-
Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine
-
Olesen J, Diener HC, Husstedt IW, et al. Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine. N Engl J Med 2004;350:1104-1110
-
(2004)
N Engl J Med
, vol.350
, pp. 1104-1110
-
-
Olesen, J.1
Diener, H.C.2
Husstedt, I.W.3
-
88
-
-
42249087655
-
Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine
-
Ho TW, Mannix LK, Fan X, et al. Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine. Neurology 2008;70:1304-1312
-
(2008)
Neurology
, vol.70
, pp. 1304-1312
-
-
Ho, T.W.1
Mannix, L.K.2
Fan, X.3
-
89
-
-
57649233374
-
Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: A randomised, placebo-controlled, parallel-treatment trial
-
Ho TW, Ferrari MD, Dodick DW, et al. Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial. Lancet 2008;372:2115-2123
-
(2008)
Lancet
, vol.372
, pp. 2115-2123
-
-
Ho, T.W.1
Ferrari, M.D.2
Dodick, D.W.3
-
90
-
-
70349682469
-
Randomized, controlled trial of telcagepant for the acute treatment of migraine
-
Connor KM, Shapiro RE, Diener HC, et al. Randomized, controlled trial of telcagepant for the acute treatment of migraine. Neurology 2009;73:970-977
-
(2009)
Neurology
, vol.73
, pp. 970-977
-
-
Connor, K.M.1
Shapiro, R.E.2
Diener, H.C.3
-
91
-
-
77953455020
-
Single-and multiple-dose pharmacokinetics and tolerability of telcagepant, an oral calcitonin gene\related peptide receptor antagonist, in adults
-
Epub ahead of print
-
Han TH, Blanchard RL, Palcza J, et al. Single-and multiple-dose pharmacokinetics and tolerability of telcagepant, an oral calcitonin gene\related peptide receptor antagonist, in adults. J Clin Pharmacol 2010. [Epub ahead of print]
-
(2010)
J Clin Pharmacol
-
-
Han, T.H.1
Blanchard, R.L.2
Palcza, J.3
-
92
-
-
61649110931
-
Preclinical pharmacokinetics of MK-0974, an orally active calcitonin-gene related peptide (CGRP)-receptor antagonist, mechanism of dose dependency and species differences
-
Roller S, Cui D, Laspina C, et al. Preclinical pharmacokinetics of MK-0974, an orally active calcitonin-gene related peptide (CGRP)-receptor antagonist, mechanism of dose dependency and species differences. Xenobiotica 2009;39:33-45
-
(2009)
Xenobiotica
, vol.39
, pp. 33-45
-
-
Roller, S.1
Cui, D.2
Laspina, C.3
-
93
-
-
67649173064
-
The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice
-
Kroeger I, Erhardt A, Abt D, et al. The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice. J Hepatol 2009;51:342-353
-
(2009)
J Hepatol
, vol.51
, pp. 342-353
-
-
Kroeger, I.1
Erhardt, A.2
Abt, D.3
-
94
-
-
2542502483
-
Consensus statement: Cardiovascular safety profile of triptans (5-HT agonists) in the acute treatment of migraine
-
Dodick D, Lipton RB, Martin V, et al. Consensus statement: cardiovascular safety profile of triptans (5-HT agonists) in the acute treatment of migraine. Headache 2004;44:414-425
-
(2004)
Headache
, vol.44
, pp. 414-425
-
-
Dodick, D.1
Lipton, R.B.2
Martin, V.3
-
95
-
-
59649083469
-
Calcitonin gene-related peptide receptor antagonism does not affect the severity of myocardial ischemia during atrial pacing in dogs with coronary artery stenosis
-
Regan CP, Stump GL, Kane SA, Lynch JJ Jr. Calcitonin gene-related peptide receptor antagonism does not affect the severity of myocardial ischemia during atrial pacing in dogs with coronary artery stenosis. J Pharmacol Exp Ther 2009;328:571-578
-
(2009)
J Pharmacol Exp Ther
, vol.328
, pp. 571-578
-
-
Regan, C.P.1
Stump, G.L.2
Kane, S.A.3
Lynch Jr., J.J.4
-
96
-
-
0037005741
-
Effect of the CGRP receptor antagonist BIBN4096BS in human cerebral, coronary and omental arteries and in SK-N-MC cells
-
Edvinsson L, Alm R, Shaw D, et al. Effect of the CGRP receptor antagonist BIBN4096BS in human cerebral, coronary and omental arteries and in SK-N-MC cells. Eur J Pharmacol 2002;434:49-53
-
(2002)
Eur J Pharmacol
, vol.434
, pp. 49-53
-
-
Edvinsson, L.1
Alm, R.2
Shaw, D.3
-
97
-
-
77952979510
-
Comparison of the vasoconstrictor effects of the calcitonin gene-related peptide (CGRP) receptor antagonist telcagepant (MK-0974) and zolmitriptan in human isolated coronary arteries
-
[Epub ahead of print]
-
Lynch JJ Jr, Regan CP, Md LE, et al. Comparison of the vasoconstrictor effects of the calcitonin gene-related peptide (CGRP) receptor antagonist telcagepant (MK-0974) and zolmitriptan in human isolated coronary arteries. J Cardiovasc Pharmacol 2010. [Epub ahead of print]
-
(2010)
J Cardiovasc Pharmacol
-
-
Regan, C.P.1
Md, L.E.2
-
98
-
-
72649098967
-
Blockade effects of BIBN4096BS on CGRP-induced inhibition on whole-cell K+ currents in spinal dorsal horn neuron of rats
-
Hou JF, Yu LC. Blockade effects of BIBN4096BS on CGRP-induced inhibition on whole-cell K+ currents in spinal dorsal horn neuron of rats. Neurosci Lett 2010;469:15-18
-
(2010)
Neurosci Lett
, vol.469
, pp. 15-18
-
-
Hou, J.F.1
Yu, L.C.2
-
99
-
-
0035904760
-
Oral triptans (serotonin 5-HT(1B/1D) agonists) in acute migraine treatment: A meta-analysis of 53 trials
-
Ferrari MD, Roon KI, Lipton RB, Goadsby PJ. Oral triptans (serotonin 5-HT(1B/1D) agonists) in acute migraine treatment: a meta-analysis of 53 trials. Lancet 2001;358:1668-1675
-
(2001)
Lancet
, vol.358
, pp. 1668-1675
-
-
Ferrari, M.D.1
Roon, K.I.2
Lipton, R.B.3
Goadsby, P.J.4
-
100
-
-
77950494037
-
Is there an inherent limit to the efficacy of calcitonin gene-related peptide receptor antagonists in the acute treatment of migraine? A comment
-
Tfelt-Hansen PC. Is there an inherent limit to the efficacy of calcitonin gene-related peptide receptor antagonists in the acute treatment of migraine? A comment. J Headache Pain 2009;10:389-391
-
(2009)
J Headache Pain
, vol.10
, pp. 389-391
-
-
Tfelt-Hansen, P.C.1
|