Messenger molecules and receptor mRNA in the human trigeminal ganglion

Journal of the Autonomic Nervous System

Volumn 76, Issue 2-3, 1999, Pages 176-183

  Tajti, Janos ^a,b   Uddman, Rolf ^a   Möller, Sebastian ^a   Sundler, Frank ^a   Edvinsson, Lars ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Human trigeminal ganglia; Immunocytochemistry; In situ hybridisation; Neuropeptides; Reverse transcriptase polymerase chain reaction

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; MESSENGER RNA; NEUROPEPTIDE; NEUROPEPTIDE Y; NITRIC OXIDE SYNTHASE; SUBSTANCE P; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR;

ADULT; AGAR GEL ELECTROPHORESIS; AGED; ARTICLE; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; IN SITU HYBRIDIZATION; MALE; MIGRAINE; PERIKARYON; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRIGEMINUS GANGLION;

EID: 0033036503     PISSN: 01651838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1838(99)00024-7     Document Type: Article

References (62)

1. Aiyar, N., Rand, K., Elshourbagy, N.A., Zeng, Z., Adamon, J.E., Bergsma, D.J., Li, Y., 1996. A cDNA encoding the calcitonin gene-related peptide type 1 receptor. J. Biol. Chem. 271, 11325-11329.
2. Anzai, M., Suzuki, Y., Takayasu, M., 1995. Vasorelaxant effect of PACAP-27 on canine cerebral arteries and rat intracerebral arterioles. Eur. J. Pharmacol. 285, 173-179.
3. Arimura, A., 1992. Pituitary adenylate cyclase activating polypeptide (PACAP): discovery and current status of research. Regul. Pept. 37, 287-303.
4. Arimura, A., Shioda, S., 1995. Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors: neuroendocrine and endocrine interactions. Front. Neuroendocrinol. 16, 53-58.
5. Blomquist, A.G., Herzog, H., 1997. Y-receptor subtypes-how many more? Trends Neurosci. 20, 294-298.
6. Buzzi, G., Carter, W.B., Shimizu, T., Heath, H., Moskowitz, M.A., 1991. Dihydroergotamine and sumatriptan attenuate levels of CGRP in plasma in rat superior sagittal sinus during electrical stimulation of the trigeminal ganglion. Neuropharmacology 40, 1193-1200.
7. (8 - 37) a calcitonin gene-related peptide receptor heterogeneity in brain and periphery. J. Pharmacol. Exp. Ther. 254, 123-128.
8. Edvinsson, L., 1985. Functional role of perivascular peptides in the control of cerebral circulation. TINS. 8, 126-131.
9. Edvinsson, L., Uddman, R., 1981. Adrenergic, cholinergic and peptidergic nerve fibers in dura mater-involvement in headache? Cephalalgia 1, 175-179.
10. Edvinsson, L., McCulloch, J., Uddman, R., 1981. Substance P: immunohistochemical localization and effect upon cat pial arteries in vitro and in situ. J. Physiol. (London) 318, 251-258.
11. Edvinsson, L., Rosendahl-Helgesen, S., Uddman, R., 1983. Substance P. Localization, concentration and release in cerebral arteries, choroid plexus and dura mater. Cell Tissue Res 234, 1-7.
12. Edvinsson, L., Fredholm, B.B., Hamel, E., Jansen, I., Verrecchia, C., 1985. Perivascular peptides relax cerebral arteries concomitant with stimulation of cyclic adenosine monophosphate accumulation or release of an endothelium-derived relaxing factor in the cat. Neurosci. Lett. 58, 213-217.
13. Edvinsson, L., Copeland, J.R., Emson, P.C., McCulloch, J., Uddman, R., 1987a. Nerve fibers containing neuropeptide Y in the cerebrovascular bed: immunocytochemistry, radioimmunoassay and vasomotor effects. J. Cereb. Blood Flow Metab. 7, 45-57.
14. Edvinsson, L., Ekman, R., Jansen, I., McCulloch, J., Uddman, R., 1987b. Calcitonin gene-related peptide and cerebral blood vessels: distribution and vasomotor effects. J. Cereb. Blood Flow Metab. 7, 720-728.
15. Edvinsson, L., Ekman, R., Jansen, I., Ottosson, A., Uddman, R., 1987c. Peptide-containing nerve fibers in human cerebral arteries: immunocytochemistry, radioimmunoassay and in vitro pharmacology. Ann. Neurol. 21, 432-437.
16. Edvinsson, L., Brodin, E., Jansen, I., Uddman, R., 1988. Neurokinin A in cerebral vessels: characterization, localization and effects in vitro. Regul. Pept. 20, 181-197.
17. Edvinsson, L., Hara, H., 1989. Retrograde tracing of nerve fibers to the rat middle cerebral artery with True Blue: co-localization with different neuropeptides. J. Cereb. Blood Flow Metab. 9, 212-218.
18. Edvinsson, L., MacKenzie, E.T., McCulloch, J., 1993. Cerebral Blood Flow and Metabolism. Raven Press, New York.
19. Edvinsson, L., Jansen, I., Cunhae Sa, M., Gulbenkian, S., 1994. Demonstration of neuropeptide containing nerves and vasomotor responses to perivascular peptides in human cerebral arteries. Cephalalgia 14, 88-96.
20. Edvinsson, L., Cantera, L., Jansen-Olesen, I., Uddman, R., 1997. Calcitonin gene-related peptide1 receptor mRNA in human trigeminal ganglia and cerebral arteries. Neurosci. Lett. 229, 209-211.
21. Edvinsson, L., Mulder, H., Goadsby, P.J., Uddman, R., 1998. Calcitonin gene-related peptide and nitric oxide in the trigeminal ganglion. Cerebral vasodilation from trigeminal nerve stimulation involves mainly calcitonin gene-related peptide. J. Auton. Nerv. Syst. 70, 15-22.
22. Goadsby, P.J., Edvinsson, L., 1993. The trigeminovascular system and migraine: studies characterizing cerebrovascular and neuropeptide changes seen in human and cats. Ann. Neurol. 33, 48-56.
23. Goadsby, P.J., Edvinsson, L., 1994. Human in vivo evidence for trigeminovascular activation in cluster headache. Neuropeptide changes and effects of acute therapies. Brain 117, 427-434.
24. Goadsby, P.J., Edvinsson, L., 1996. Neuropeptide changes in a case of chronic paroxysmal hemicrania—evidence for trigemino-parasympathetic activation. Cephalalgia 16, 448-450.
25. Goadsby, P.J., Edvinsson, L., Ekman, R., 1988. Release of vasoactive peptides in the extracerebral circulation of humans and the cat during activation of the trigeminovascular system. Ann. Neurol. 23, 193-196.
26. Goadsby, P.J., Edvinsson, L., Ekman, R., 1990. Vasoactive peptide release in the extracerebral circulation of humans during migraine headache. Ann. Neurol. 28, 183-187.
27. Goadsby, P.J., Uddman, R., Edvinsson, L., 1996. Cerebral vasodilatation in the cat involves nitric oxide from parasympathetic nerves. Brain Res. 707, 110-118.
28. Goldstein, D.J., Wang, O., Saper, J.R., Stoltz, R., Silberstein, S.D., Mathew, N.T., 1997. Ineffectiveness of neurokinin-1 antagonist in acute migraine: a crossover study. Cephalalgia 17, 785-790.
29. Holfhusen, H., Kindgen-Milles, D., Ding, Z.P., 1997. Substance P is not involved in vascular nociception in humans. Neuropeptides 31, 445- 448.
30. Jansen, I., Alafaci, C., McCulloch, J., Uddman, R., Edvinsson, L., 1991. Tachykinins (substance P, neurokinin A, neuropeptide K and neu- rokinin B) in the cerebral circulation: vasomotor responses in vitro and in situ. J. Cereb. Blood Flow Metab. 11, 567-575.
31. Jansen, I., Uddman, R., Ekman, R., Olesen, J., Ottosson, A., Edvinsson, L., 1992. Distribution and effects of neuropeptide Y, vasoactive intestinal peptide, substance P, and calcitonin gene-related peptide in human middle meningeal arteries: comparison with cerebral and temporal arteries. Peptides 13, 527-536.
32. Jansen-Olesen, I., Mortensen, A., Edvinsson, L., 1996. Calcitonin generelated peptide is released from capsaicin-sensitive nerve fibres and induces vasodilatation of human cerebral arteries concomitant with activation of adenylyl cyclase. Cephalalgia 16, 310-316.
33. Knyihar-Csillik, E., Tajti, J., Samsam, M., Sary, G., Vecsei, L., 1995. Electrical stimulation of the Gasserian ganglion induced structural alterations of calcitonin gene-related peptide-immunoreactive perivascular sensory nerve terminals in the rat cerebral dura mater: possible model of migraine headache. Neurosci. Lett. 184, 189-192.
34. Lassen, L.H., Thomsen, L.L., Olesen, J., 1995. Histamine induces migraine via the H1-receptor. Support for the NO hypothesis of migraine. NeuroReport 6, 1475-1479.
35. Markowitz, S., Saito, K., Moskowitz, M.A., 1987. Neurogenically mediated leakage of plasma protein occurs from blood vessels in dura mater but not brain. J. Neurosci. 7, 4129-4136.
36. Mayberg, M., Langers, R.S., Zervos, N.T., Moskowitz, M.A., 1981. Perivascular meningeal projections from cat trigeminal ganglia: possible pathway for vascular headache in man. Science 213, 228-230.
37. McCulloch, J., Uddman, R., Kingman, T.A., Edvinsson, L., 1986. Calcitonin gene-related peptide: functional role in cerebrovascular regulation. Proc. Natl. Acad. Sci. U.S.A. 83, 5731-5735.
38. Moller, K., Zhang, Y.-Z., Håkanson, R., Luts, A., Sjölund, B., Uddman, R., Sundler, F., 1993. Pituitary adenylate cyclase activating peptide is a sensory neuropeptide: immunocytochemical and immunochemical evidence. Neuroscience 57, 725-732.
39. Moskowitz, M.A., 1984. The neurobiology of vascular head pain. Ann. Neurol. 16, 157-168.
40. Mulder, H., Uddman, R., Moller, K., Zhang, Y.-Z., Ekblad, E., Alumets, J., Sundler, F., 1994. Pituitary adenylate cyclase activating polypeptide expression in sensory neurons. Neuroscience 63, 307-312.
41. Mulder, H., Uddman, R., Moller, K., Elsas, T., Ekblad, E., Alumets, J., Sundler, F., 1995. Pituitary adenylate cyclase activating polypeptide is expressed in autonomic neurons. Regul. Pept. 59, 121-128.
42. Nilsson, T., Cantera, L., Edvinsson, L., 1996. Presence of neuropeptide Y Y1 receptor mediating vasoconstriction in human cerebral arteries. Neurosci. Lett. 204, 145-148.
43. Nozaki, K., Moskowitz, M.A., Maynard, K.I., Koketsu, N., Dawson, T.M., Bredt, D.S., Snyder, S.H., 1993. Possible origins and distribution of immunoreactive nitric oxide synthase-containing nerve fibers in cerebral arteries. J. Cereb. Blood Flow Metab. 13, 70-79.
44. Olesen, J., Thomsen, L.L., Lassen, L.H., Olesen, I.J., 1995. The nitric oxide hypothesis of migraine and other vascular headaches. Cephalalgia 15, 94-100.
45. Phebus, L.A., Johnson, K.W., Stengel, P.W., Lobb, K.L., Nixon, J.A., Hipskind, P.A., 1997. The non-peptide NK-1 receptor antagonist LY303870 inhibits neurogenic dural inflammation in guinea pigs. Life. Sci. 60, 1553-1561.
46. Quartu, M., Floris, A., Del Fiacco, M., 1990. Substance P- and calcitonin gene-related peptide-like immunoreactive pericellular baskets in human trigeminal ganglion. Bas. Appl. Histochem. 34, 177-181.
47. Quartu, M., Diaz, G., Floris, A., Lai, M.L., Priestley, J.V., Del Fiacco, M., 1992. Calcitonin gene-related peptide in the human trigeminal sensory system at developmental and adult life stages: immunohistochemistry neuronal morphometry and coexistence with substance P. J. Chem. Neuroanat. 5, 143-157.
48. Ray, B.S., Wolff, H.G., 1940. Experimental studies on headache. Pain sensitive structures of the head and their significance in headache. Arch. Surg. 41, 813-856.
49. Rose, P.M., Prabhavathi, F., Lynch, J.S., Fraizer, S.T., Fisher, S.M., Kodukula, K., Kienzle, B., Seethala, R., 1995. Cloning and functional expression of a cDNA encoding a human type 2 neuropeptide Y receptor. J. Biol. Chem. 270, 22661-22664.
50. Rosenfeld, M.G., Mermod, J.J., Amara, S.G., Swanson, S.W., Sawschenko, P.E., Rivier, J., Vale, W.W., Evans, R.M., 1983. Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing. Nature 304, 129-135.
51. Schon, F., Ghatei, M., Allen, J.M., Mulderry, P.K., Kelly, J.S., Bloom, S.R., 1985. The effect of sympathectomy on calcitonin gene-related peptide levels in the rat trigeminovascular system. Brain Res. 348, 197-200.
52. Seki, Y., Suzuki, Y., Baskaya, M.K., 1995. The effects of pituitary adenylate cyclase-activating polypeptide on cerebral arteries and vertebral artery blood flow in anesthetized dogs. Eur. J. Pharmacol. 275, 259-266.
53. Shepheard, S.L., Williamson, D.J., Hill, R.G., Hargreaves, R.J., 1993. The non-peptide neurokinin-1 receptor antagonist RP67580, blocks neurogenic plasma extravasation in the dura mater of rats. Br. J. Pharm. 108, 11-12.
54. Shepheard, S.L., Williamson, D.J., Cook, D., Williams, J., Sirinathsinghji, D., Heavens, R., Hill, R.G., Hargreaves, R.J., 1994. The NK1 receptor antagonist CP-99,994 blocks dural extravasation and c-fos expression produced by electrical stimulation of the trigeminal ganglion in rats. Br. J. Pharm. 112, 609-612.
55. Shepheard, S.L., Williamson, D.J., Williams, J., Hill, R.G., Hargreaves, R.J., 1995. Comparison of the effects of Sumatriptan and the NK1 antagonist CP-99,994 on plasma extravasation in dura mater and c-fos mRNA expression in trigeminal nucleus caudalis of rats. Neuropharmacology 34, 255-261.
56. Sreedharan, S.P., Patel, D.R., Huang, J.X., Goetzl, E.J., 1993. Cloning and functional expression of a human neuroendocrine vasoactive intestinal peptide receptor. Biochem. Biophys. Res. Commun. 193, 546-553.
57. Thomsen, L.L., Iversen, H.K., Brinck, T.A., Olesen, J., 1993. Arterial supersensitivity to nitric oxide (nitroglycerin) in migraine sufferers. Cephalalgia 13, 395-399.
58. Uddman, R., Edvinsson, L., Ekman, R., Kingman, T., McCulloch, J., 1985. Innervation of the feline cerebral vasculature by nerve fibers containing calcitonin gene-related peptide: trigeminal origin and coexistence with substance P. Neurosci. Lett. 62, 131-136.
59. Uddman, R., Goadsby, P.J., Jansen, I., Edvinsson, L., 1993. PACAP, a VIP-like peptide: immunohistochemical localization and effect upon cat pial arteries and cerebral blood flow. J. Cereb. Blood Flow Metab. 13, 291-297.
60. Uddman, R., Mulder, H., Sundelin, J., Elsås, T., Sundler, F., 1994. Nitric oxide synthase expression in cervical autonomic and sensory ganglia in rat: relationship to neuropeptides. Cell Vision 1, 306-312.
61. Wahlestedt, C., Yanaihara, N., Håkanson, R., 1986. Evidence for different pre- and postjunctional receptors for neuropeptide Y and related peptides. Regul. Pept 13, 307-318.
62. Zagami, A.S., Goadsby, P.J., Edvinsson, L., 1990. Stimulation of the superior sagittal sinus in the cat causes release of vasoactive peptides. Neuropeptides 16, 69-75.