메뉴 건너뛰기




Volumn 25, Issue 1, 2010, Pages 114-123

Restoration of regenerative osteoblastogenesis in aged mice: Modulation of TNF

Author keywords

Aging; Bone repair; Cytokine; TNF

Indexed keywords

ANABOLIC AGENT; CYCLIN DEPENDENT KINASE INHIBITOR 1A; ETANERCEPT; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR INHIBITOR; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2;

EID: 77953402288     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.090708     Document Type: Article
Times cited : (54)

References (66)
  • 4
    • 0035985878 scopus 로고    scopus 로고
    • Osteoporosis in men: Pathophysiology, evaluation, and therapy
    • Burgess E, Nanes MS. Osteoporosis in men: pathophysiology, evaluation, and therapy. Curr Opin Rheumatol. 2002;14:421-428.
    • (2002) Curr Opin Rheumatol , vol.14 , pp. 421-428
    • Burgess, E.1    Nanes, M.S.2
  • 5
    • 39149143035 scopus 로고    scopus 로고
    • Molecular mechanisms controlling bone formation during fracture healing and distraction osteogenesis
    • Ai-Aql ZS, Alagl AS, Graves DT, Gerstenfeld LC, Einhorn TA. Molecular mechanisms controlling bone formation during fracture healing and distraction osteogenesis. J Dent Res. 2008;87:107-118.
    • (2008) J Dent Res , vol.87 , pp. 107-118
    • Ai-Aql, Z.S.1    Alagl, A.S.2    Graves, D.T.3    Gerstenfeld, L.C.4    Einhorn, T.A.5
  • 6
    • 33847306495 scopus 로고    scopus 로고
    • Bone formation after damaging in vivo fatigue loading results in recovery of whole-bone monotonic strength and increased fatigue life
    • Silva MJ, Touhey DC. Bone formation after damaging in vivo fatigue loading results in recovery of whole-bone monotonic strength and increased fatigue life. J Orthop Res. 2007;25:252-261.
    • (2007) J Orthop Res , vol.25 , pp. 252-261
    • Silva, M.J.1    Touhey, D.C.2
  • 7
    • 58249105081 scopus 로고    scopus 로고
    • Stress fracture healing: Fatigue loading of the rat ulna induces upregulation in expression of osteogenic and angiogenic genes that mimic the intramembranous portion of fracture repair
    • Wohl GR, Towler DA, Silva MJ. Stress fracture healing: fatigue loading of the rat ulna induces upregulation in expression of osteogenic and angiogenic genes that mimic the intramembranous portion of fracture repair. Bone. 2009;44:320-330.
    • (2009) Bone , vol.44 , pp. 320-330
    • Wohl, G.R.1    Towler, D.A.2    Silva, M.J.3
  • 10
    • 10044241572 scopus 로고    scopus 로고
    • IL-1 and TNF antagonists prevent inhibition of fracture healing by ethanol in rats
    • Perrien DS, Wahl EC, Hogue WR, et al. IL-1 and TNF antagonists prevent inhibition of fracture healing by ethanol in rats. Toxicol Sci. 2004;82:656-660.
    • (2004) Toxicol Sci , vol.82 , pp. 656-660
    • Perrien, D.S.1    Wahl, E.C.2    Hogue, W.R.3
  • 12
    • 33646071554 scopus 로고    scopus 로고
    • Management of nonunion with distraction osteogenesis
    • Kanellopoulos AD, Soucacos PN. Management of nonunion with distraction osteogenesis. Injury. 2006;37:S51-55.
    • (2006) Injury , vol.37
    • Kanellopoulos, A.D.1    Soucacos, P.N.2
  • 13
    • 13244267048 scopus 로고    scopus 로고
    • Infected nonunion of the long bones
    • Jain AK, Sinha S. Infected nonunion of the long bones. Clin Orthop Relat Res. 2005;431:57-65.
    • (2005) Clin Orthop Relat Res , vol.431 , pp. 57-65
    • Jain, A.K.1    Sinha, S.2
  • 14
    • 0027943787 scopus 로고
    • Experimental and clinical experience with distraction osteogenesis
    • DOI 10.1597/1545-1569(1994)031<0473:EACEWD>2.3.CO;2
    • Aronson J. Experimental and clinical experience with distraction osteogenesis. Cleft Palate Craniofac J. 1994;31:473-481; discussion 481-282. (Pubitemid 24367053)
    • (1994) Cleft Palate-Craniofacial Journal , vol.31 , Issue.6 , pp. 473-482
    • Aronson, J.1    McCarthy, J.G.2
  • 16
    • 0029936531 scopus 로고    scopus 로고
    • A review of 240 patients undergoing distraction osteogenesis for congenital post-traumatic or postinfective lower limb length discrepancy
    • Maffulli N, Lombari C, Matarazzo L, Nele U, Pagnotta G, Fixsen JA. A review of 240 patients undergoing distraction osteogenesis for congenital post-traumatic or postinfective lower limb length discrepancy. J Am Coll Surg. 1996;182:394-402. (Pubitemid 26139382)
    • (1996) Journal of the American College of Surgeons , vol.182 , Issue.5 , pp. 394-402
    • Maffulli, N.1    Lombari, C.2    Matarazzo, L.3    Nele, U.4    Pagnotta, G.5    Fixsen, J.A.6
  • 17
    • 0032170245 scopus 로고    scopus 로고
    • Histochemical and molecular analyses of distraction osteogenesis in a mouse model
    • Tay BK, Le AX, Gould SE, Helms JA. Histochemical and molecular analyses of distraction osteogenesis in a mouse model. J Orthop Res. 1998;16:636-642.
    • (1998) J Orthop Res , vol.16 , pp. 636-642
    • Tay, B.K.1    Gould Se, L.A.X.2    Helms, J.A.3
  • 20
    • 0033911488 scopus 로고    scopus 로고
    • Inflamm-aging: An evolutionary perspective on immunosenescence
    • Franceschi C, Bonafe M, Valensin S, et al. Inflamm-aging: an evolutionary perspective on immunosenescence. Ann NY Acad Sci. 2000;908:244-254.
    • (2000) Ann NY Acad Sci , vol.908 , pp. 244-254
    • Franceschi, C.1    Bonafe, M.2    Valensin, S.3
  • 21
    • 22144457627 scopus 로고    scopus 로고
    • Inflammatory bone destruction and osteoimmunology
    • Takayanagi H. Inflammatory bone destruction and osteoimmunology. J Periodontal Res. 2005;40:287-293.
    • (2005) J Periodontal Res , vol.40 , pp. 287-293
    • Takayanagi, H.1
  • 22
    • 0242409906 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha: Molecular and cellular mechanisms in skeletal pathology
    • Nanes MS. tumor necrosis factor-alpha: molecular and cellular mechanisms in skeletal pathology. Gene. 2003;321:1-15.
    • (2003) Gene , vol.321 , pp. 1-15
    • Nanes, M.S.1
  • 23
    • 0029802660 scopus 로고    scopus 로고
    • Estrogen deficiency increases the ability of stromal cells to support murine osteoclastogenesis via an interleukin-1-and tumor necrosis factor- Mediated stimulation of macrophage colony-stimulating factor production
    • DOI 10.1074/jbc.271.46.28890
    • Kimble RB, Srivastava S, Ross FP, Matayoshi A, Pacifici R. Estrogen deficiency increases the ability of stromal cells to support murine osteoclastogenesis via an interleukin-1 and tumor necrosis factor-mediated stimulation macrophage colony stimulating factor production. J Biol Chem. 1996;271:28890-28897. (Pubitemid 26382589)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.46 , pp. 28890-28897
    • Kimble, R.B.1    Srivastava, S.2    Patrick Ross, F.3    Matayoshi, A.4    Pacifici, R.5
  • 25
    • 0033764665 scopus 로고    scopus 로고
    • Tumor necrosis factors receptor associated signaling molecules and their role in activation of apoptosis, Jnk and Nf-κB
    • Aggarwal B. Tumor necrosis factors receptor associated signaling molecules and their role in activation of apoptosis, Jnk and Nf-κB. Ann Rheum Dis. 2000;59:I6-I6.
    • (2000) Ann Rheum Dis , vol.59
    • Aggarwal, B.1
  • 26
    • 15444367188 scopus 로고    scopus 로고
    • Integration of the NfκB p65 subunit into the vitamin D receptor transcriptional complex: Identification of p65 domains that inhibit 1,25-dihydroxyvitamin D3-stimulated transcription
    • DOI 10.1002/jcb.20143
    • Lu X, Farmer P, Rubin J, Nanes M. Integration of the NfκB P65 subunit into the vitamin D receptor transcriptional complex: identification of P65 domains that inhibit 1,25-dihydroxyvitamin D3-stimulated transcription. J Cell Biochem. 2004;92:833-848. (Pubitemid 44264272)
    • (2004) Journal of Cellular Biochemistry , vol.92 , Issue.4 , pp. 833-848
    • Lu, X.1    Farmer, P.2    Rubin, J.3    Nanes, M.S.4
  • 27
    • 33646588049 scopus 로고    scopus 로고
    • Transcriptional regulation of the osterix (Osx, Sp7) promoter by tumor necrosis factor identifies disparate effects of mitogen-activated protein kinase and NFκB pathways
    • DOI 10.1074/jbc.M507804200
    • Lu X, Gilbert L, He X, Rubin J, Nanes M. Transcriptional regulation of the Osterix (Osx, Sp7) promoter by tumor necrosis factor identifies disparate effects of mitogen-activated protein kinase and NFκB pathways. J Biol Chem. 2006;281: 6297-6306. (Pubitemid 43847561)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.10 , pp. 6297-6306
    • Lu, X.1    Gilbert, L.2    He, X.3    Rubin, J.4    Nanes, M.S.5
  • 29
  • 30
    • 0034953367 scopus 로고    scopus 로고
    • Impaired intramembranous bone formation during bone repair in the absence of tumor necrosis factor-alpha signaling
    • DOI 10.1159/000047893
    • Gerstenfeld L, Cho T, Kon T, et al. Impaired intramembranous bone formation during bone repair in the absence of tumor necrosis factor-α signaling. Cells Tissues Organs. 2001;169:285-294. (Pubitemid 32656656)
    • (2001) Cells Tissues Organs , vol.169 , Issue.3 , pp. 285-294
    • Gerstenfeld, L.C.1    Cho, T.-J.2    Kon, T.3    Aizawa, T.4    Cruceta, J.5    Graves, B.D.6    Einhorn, T.A.7
  • 32
    • 48449088578 scopus 로고    scopus 로고
    • Proinflammatory cytokine-induced cellular senescence of biliary epithelial cells is mediated via oxidative stress and activation of ATM pathway: A culture study
    • Sasaki M, Ikeda H, Sato Y, Nakanuma Y. Proinflammatory cytokine-induced cellular senescence of biliary epithelial cells is mediated via oxidative stress and activation of ATM pathway: a culture study. Free Radical Res. 2008;42:625-632.
    • (2008) Free Radical Res , vol.42 , pp. 625-632
    • Sasaki, M.1    Ikeda, H.2    Sato, Y.3    Nakanuma, Y.4
  • 33
    • 58649095889 scopus 로고    scopus 로고
    • Ethanol impairs estrogen receptor signaling resulting in accelerated activation of senescence pathways, whereas estradiol attenuates the effects of ethanol in osteoblasts
    • Chen JR, Lazarenko OP, Haley RL, Blackburn ML, Badger TM, Ronis MJ. Ethanol impairs estrogen receptor signaling resulting in accelerated activation of senescence pathways, whereas estradiol attenuates the effects of ethanol in osteoblasts. J Bone Miner Res. 2009;24:221-230.
    • (2009) J Bone Miner Res , vol.24 , pp. 221-230
    • Chen, J.R.1    Lazarenko, O.P.2    Haley, R.L.3    Blackburn, M.L.4    Badger, T.M.5    Ronis, M.J.6
  • 40
    • 0022648104 scopus 로고
    • Stimulation of bone resorption and inhibition of bone formation in vitro by tumor necrosis factors
    • Bertolini DR, Nedwin GE, Bringman TS, Smith DD, Mundy GR. Stimulation of bone resorption and inhibition of bone formation in vitro by tumor necrosis factors. Nature. 1986;19:516-518.
    • (1986) Nature , vol.19 , pp. 516-518
    • Bertolini, D.R.1    Nedwin, G.E.2    Bringman, T.S.3    Smith, D.D.4    Mundy, G.R.5
  • 43
    • 34547561383 scopus 로고    scopus 로고
    • Bone mass is inversely proportional to Dkk1 levels in mice
    • MacDonald BT, Joiner DM, Oyserman SM, et al. Bone mass is inversely proportional to Dkk1 levels in mice. Bone. 2007;41:331-339.
    • (2007) Bone , vol.41 , pp. 331-339
    • MacDonald, B.T.1    Joiner, D.M.2    Oyserman, S.M.3
  • 44
    • 0042346318 scopus 로고    scopus 로고
    • The Wnt signaling inhibitor Dickkopf-1 is required for reentry into the cell cycle of human adult stem cells from bone marrow
    • DOI 10.1074/jbc.M300373200
    • Gregory CA, Singh H, Perry AS, Prockop DJ. The Wnt signaling inhibitor dickkopf-1 is required for reentry into the cell cycle of human adult stem cells from bone marrow. J Biol Chem. 2003;278:28067-28078. (Pubitemid 36900004)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.30 , pp. 28067-28078
    • Gregory, C.A.1    Singh, H.2    Perry, A.S.3    Prockop, D.J.4
  • 45
    • 37749040562 scopus 로고    scopus 로고
    • Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSF
    • Fujita K, Janz S. Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSF. Mol Cancer. 2007;6:71.
    • (2007) Mol Cancer , vol.6 , pp. 71
    • Fujita, K.1    Janz, S.2
  • 46
    • 40649090823 scopus 로고    scopus 로고
    • Identification of replicative senescence-associated genes in human umbilical vein endothelial cells by an annealing control primer system
    • Kim TW, Kim HJ, Lee C, et al. Identification of replicative senescence-associated genes in human umbilical vein endothelial cells by an annealing control primer system. Exp Gerontol. 2008;43:286-295.
    • (2008) Exp Gerontol , vol.43 , pp. 286-295
    • Kim, T.W.1    Kim, H.J.2    Lee, C.3
  • 47
    • 33847027624 scopus 로고    scopus 로고
    • Genes with greater up-regulation in the fracture callus of older rats with delayed healing
    • Meyer MH, Meyer RA Jr. Genes with greater up-regulation in the fracture callus of older rats with delayed healing. J Orthop Res. 2007;25:488-494.
    • (2007) J Orthop Res , vol.25 , pp. 488-494
    • Meyer, M.H.1    Meyer Jr., R.A.2
  • 49
    • 0031006203 scopus 로고    scopus 로고
    • Circulating levels of insulin-like growth factor (IGF) binding protein-1 and -3 in aging men: Relationships to insulin, glucose, IGF, and dehydroepiandrosterone sulfate levels and anthropometric measures
    • Benbassat CA, Maki KC, Unterman TG. Circulating levels of insulin-like growth factor (IGF) binding protein-1 and -3 in aging men: relationships to insulin, glucose, IGF, and dehydroepiandrosterone sulfate levels and anthropometric measures. J Clin Endocrinol Metab. 1997;82:1484-1491.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1484-1491
    • Benbassat, C.A.1    Maki, K.C.2    Unterman, T.G.3
  • 50
    • 33746737393 scopus 로고    scopus 로고
    • Osteogenic differentiation of mouse embryonic stem cells and mouse embryonic fibroblasts in a three-dimensional self-assembling peptide scaffold
    • Garreta E, Genové E, Borrós S, Semino CE. Osteogenic differentiation of mouse embryonic stem cells and mouse embryonic fibroblasts in a three-dimensional self-assembling peptide scaffold. Tissue Eng. 2006;12:2215-2227.
    • (2006) Tissue Eng , vol.12 , pp. 2215-2227
    • Garreta, E.1    Genové, E.2    Borrós, S.3    Semino, C.E.4
  • 52
    • 0024602702 scopus 로고
    • TNF in combination with interferon-γ is cytotoxic to normal, untransformed mouse and rat embryo fibroblast-like cells
    • Suffys P, Beyaert R, Van Roy F, Fiers W. TNF in combination with interferon-γ is cytotoxic to normal, untransformed mouse and rat embryo fibroblast-like cells. Anticancer Res. 1989;9:167-171.
    • (1989) Anticancer Res , vol.9 , pp. 167-171
    • Suffys, P.1    Beyaert, R.2    Van Roy, F.3    Fiers, W.4
  • 53
    • 12144288066 scopus 로고    scopus 로고
    • A twist code determines the onset of osteoblast differentiation
    • Bialek P, Kern B, Yang X, et al. A twist code determines the onset of osteoblast differentiation. Dev Cell. 2004;6:423-435.
    • (2004) Dev Cell , vol.6 , pp. 423-435
    • Bialek, P.1    Kern, B.2    Yang, X.3
  • 54
    • 34447125073 scopus 로고    scopus 로고
    • The retinoblastoma protein is an essential mediator of osteogenesis that links the p204 protein to the Cbfa1 transcription factor thereby increasing its activity
    • Luan Y, Yu XP, Xu K, et al. The retinoblastoma protein is an essential mediator of osteogenesis that links the p204 protein to the Cbfa1 transcription factor thereby increasing its activity. J Biol Chem. 2007;282:16860-16870.
    • (2007) J Biol Chem , vol.282 , pp. 16860-16870
    • Luan, Y.1    Yu, X.P.2    Xu, K.3
  • 55
    • 22344436360 scopus 로고    scopus 로고
    • p21WAF1/CIP1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation
    • Devgan V, Mammucari C, Millar SE, Brisken C, Dotto GP. p21WAF1/CIP1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes Dev. 2005;19:1485-1495.
    • (2005) Genes Dev , vol.19 , pp. 1485-1495
    • Devgan, V.1    Mammucari, C.2    Millar, S.E.3    Brisken, C.4    Dotto, G.P.5
  • 56
    • 0032170245 scopus 로고    scopus 로고
    • Histochemical and molecular analyses of distraction osteogenesis in a mouse model
    • Tay B, Le A, Gould S, Helms J. Histochemical and molecular analyses of distraction osteogenesis in a mouse model. J Orthop Res. 1998;16:636-642.
    • (1998) J Orthop Res , vol.16 , pp. 636-642
    • Tay, B.1    Le, A.2    Gould, S.3    Helms, J.4
  • 57
    • 0033766059 scopus 로고    scopus 로고
    • A murine model of distraction osteogenesis
    • Isefuku S, Joyner C, Simpson A. A murine model of distraction osteogenesis. Bone. 2000;27:661-665.
    • (2000) Bone , vol.27 , pp. 661-665
    • Isefuku, S.1    Joyner, C.2    Simpson, A.3
  • 58
    • 2342506584 scopus 로고    scopus 로고
    • The role of angiogenesis in a murine model of distraction osteogenesis
    • Carvalho R, Einhorn T, Lehmann W, et al. The role of angiogenesis in a murine model of distraction osteogenesis. Bone. 2004;34:849.
    • (2004) Bone , vol.34 , pp. 849
    • Carvalho, R.1    Einhorn, T.2    Lehmann, W.3
  • 59
    • 58149107786 scopus 로고    scopus 로고
    • The osteogenic-angiogenic interface: Novel insights into the biology of bone formation and fracture repair
    • Towler DA. The osteogenic-angiogenic interface: novel insights into the biology of bone formation and fracture repair. Curr Osteoporos Rep. 2008;6:67-71.
    • (2008) Curr Osteoporos Rep , vol.6 , pp. 67-71
    • Towler, D.A.1
  • 60
    • 21744448879 scopus 로고    scopus 로고
    • Ethanol modulation of TNF-α biosynthesis and signaling in endothelial cells: Synergistic augmentation of TNF-alpha mediated endothelial cell dysfunctions by chronic ethanol
    • Luedemann C, Bord E, Qin G, et al. Ethanol modulation of TNF-α biosynthesis and signaling in endothelial cells: synergistic augmentation of TNF-alpha mediated endothelial cell dysfunctions by chronic ethanol. Alcohol Clin Exp Res. 2005;29:930-938.
    • (2005) Alcohol Clin Exp Res , vol.29 , pp. 930-938
    • Luedemann, C.1    Bord, E.2    Qin, G.3
  • 61
    • 22144443812 scopus 로고    scopus 로고
    • The cytoskeletal protein ezrin regulates Ec proliferation and angiogenesis via TNF-α-Induced transcriptional repression of cyclin A
    • Kishore R, Qin G, Luedemann C, et al. The cytoskeletal protein ezrin regulates Ec proliferation and angiogenesis via TNF-α-Induced transcriptional repression of cyclin A. J Clin Invest. 2005;115:1785-1796.
    • (2005) J Clin Invest , vol.115 , pp. 1785-1796
    • Kishore, R.1    Qin, G.2    Luedemann, C.3
  • 62
    • 33646350024 scopus 로고    scopus 로고
    • Cell cycle-dependent phosphorylation of the Runx2 transcription factor by CDC2 regulates endothelial cell proliferation
    • Qiao M, Shapiro P, Fosbrink M, Rus H, Kumar R, Passaniti A. Cell cycle-dependent phosphorylation of the Runx2 transcription factor by CDC2 regulates endothelial cell proliferation. J Biol Chem. 2006;281:7118-7128.
    • (2006) J Biol Chem , vol.281 , pp. 7118-7128
    • Qiao, M.1    Shapiro, P.2    Fosbrink, M.3    Rus, H.4    Kumar, R.5    Passaniti, A.6
  • 64
    • 34447509873 scopus 로고    scopus 로고
    • Endogenous TNFα lowers mazimum peak bone mass and inhibits osteoblastic smad activation through NF-κB
    • Li Y, Li A, Strait K, Zhang H, Nanes MS, Weitzman M. Endogenous TNFα lowers mazimum peak bone mass and inhibits osteoblastic smad activation through NF-κB. J Bone Miner Res. 2007;22:646-655.
    • (2007) J Bone Miner Res , vol.22 , pp. 646-655
    • Li, Y.1    Li, A.2    Strait, K.3    Zhang, H.4    Nanes, M.S.5    Weitzman, M.6
  • 65
    • 34447303828 scopus 로고    scopus 로고
    • Effect of blockade of TNF-α and interleukin-1 action on bone resorption in early postmenopausal women
    • Charatcharoenwitthaya N, Khosla S, Atkinson E, McCready L, Riggs B. Effect of blockade of TNF-α and interleukin-1 action on bone resorption in early postmenopausal women. J Bone Miner Res. 2007;22:724-729.
    • (2007) J Bone Miner Res , vol.22 , pp. 724-729
    • Charatcharoenwitthaya, N.1    Khosla, S.2    Atkinson, E.3    McCready, L.4    Riggs, B.5
  • 66
    • 34447531402 scopus 로고    scopus 로고
    • Inflammatory markers and incident fracture risk in older men and women: The Health Aging and Body Composition Study
    • Cauley J, Danielson M, Boudreau R, et al. Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition Study. J Bone Miner Res. 2007;22:1088-1095.
    • (2007) J Bone Miner Res , vol.22 , pp. 1088-1095
    • Cauley, J.1    Danielson, M.2    Boudreau, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.