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Volumn 6, Issue 2, 2008, Pages 67-71

The osteogenic-angiogenic interface: Novel insights into the biology of bone formation and fracture repair

Author keywords

[No Author keywords available]

Indexed keywords

CD146 ANTIGEN; VASCULOTROPIN; BMP2 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN 2; UNCLASSIFIED DRUG;

EID: 58149107786     PISSN: 15441873     EISSN: 15442241     Source Type: Journal    
DOI: 10.1007/s11914-008-0012-x     Document Type: Review
Times cited : (51)

References (43)
  • 1
    • 0141920503 scopus 로고    scopus 로고
    • Burden of major musculoskeletal conditions
    • Woolf AD, Pfleger B: Burden of major musculoskeletal conditions. Bull World Health Organ 2003, 81: 646-656.
    • (2003) Bull World Health Organ , vol.81 , pp. 646-656
    • Woolf, A.D.1    Pfleger, B.2
  • 2
    • 0036339867 scopus 로고    scopus 로고
    • Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis
    • Zelzer E, McLean W, Ng YS, et al.: Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development 2002, 129: 1893-1904.
    • (2002) Development , vol.129 , pp. 1893-1904
    • Zelzer, E.1    McLean, W.2    Ng, Y.S.3
  • 3
    • 2342506584 scopus 로고    scopus 로고
    • The role of angiogenesis in a murine tibial model of distraction osteogenesis
    • Carvalho RS, Einhorn TA, Lehmann W, et al.: The role of angiogenesis in a murine tibial model of distraction osteogenesis. Bone 2004, 34: 849-861.
    • (2004) Bone , vol.34 , pp. 849-861
    • Carvalho, R.S.1    Einhorn, T.A.2    Lehmann, W.3
  • 4
    • 34548441087 scopus 로고    scopus 로고
    • Differential functions of tumor necrosis factor receptor 1 and 2 signaling in ischemia-mediated arteriogenesis and angiogenesis
    • Luo D, Luo Y, He Y, et al.: Differential functions of tumor necrosis factor receptor 1 and 2 signaling in ischemia-mediated arteriogenesis and angiogenesis. Am J Pathol 2006, 169: 1886-1898.
    • (2006) Am J Pathol , vol.169 , pp. 1886-1898
    • Luo, D.1    Luo, Y.2    He, Y.3
  • 5
    • 33748292990 scopus 로고    scopus 로고
    • Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis
    • He Y, Luo Y, Tang S, et al.: Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis. J Clin Invest 2006, 116: 2344-2355.
    • (2006) J Clin Invest , vol.116 , pp. 2344-2355
    • He, Y.1    Luo, Y.2    Tang, S.3
  • 6
    • 34249913494 scopus 로고    scopus 로고
    • The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development
    • Wang Y, Wan C, Deng L, et al.: The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development. J Clin Invest 2007, 117: 1616-1626.
    • (2007) J Clin Invest , vol.117 , pp. 1616-1626
    • Wang, Y.1    Wan, C.2    Deng, L.3
  • 7
    • 38649128127 scopus 로고    scopus 로고
    • Activation of the hypoxia-inducible factor-1alpha pathway accelerates bone regeneration
    • Wan C, Gilbert SR, Wang Y, et al.: Activation of the hypoxia-inducible factor-1alpha pathway accelerates bone regeneration. Proc Natl Acad Sci U S A 2008, 105: 686-691.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 686-691
    • Wan, C.1    Gilbert, S.R.2    Wang, Y.3
  • 8
    • 2542631833 scopus 로고    scopus 로고
    • VEGFA is necessary for chondrocyte survival during bone development
    • Zelzer E, Mamluk R, Ferrara N, et al.: VEGFA is necessary for chondrocyte survival during bone development. Development 2004, 131: 2161-2171.
    • (2004) Development , vol.131 , pp. 2161-2171
    • Zelzer, E.1    Mamluk, R.2    Ferrara, N.3
  • 9
    • 25144511910 scopus 로고    scopus 로고
    • The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions
    • Takahashi H, Shibuya M: The vascular endothelial growth factor (VEGF)/ VEGF receptor system and its role under physiological and pathological conditions. Clin Sci (Lond) 2005, 109: 227-241.
    • (2005) Clin Sci (Lond) , vol.109 , pp. 227-241
    • Takahashi, H.1    Shibuya, M.2
  • 10
    • 0034914814 scopus 로고    scopus 로고
    • Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2
    • Zelzer E, Glotzer DJ, Hartmann C, et al.: Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2. Mech Dev 2001, 106: 97-106.
    • (2001) Mech Dev , vol.106 , pp. 97-106
    • Zelzer, E.1    Glotzer, D.J.2    Hartmann, C.3
  • 11
    • 0026468180 scopus 로고
    • A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
    • Semenza GL, Wang GL: A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 1992, 12: 5447-5454.
    • (1992) Mol Cell Biol , vol.12 , pp. 5447-5454
    • Semenza, G.L.1    Wang, G.L.2
  • 12
    • 0029761644 scopus 로고    scopus 로고
    • Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
    • Forsythe JA, Jiang BH, Iyer NV, et al.: Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol 1996, 16: 4604-4613.
    • (1996) Mol Cell Biol , vol.16 , pp. 4604-4613
    • Forsythe, J.A.1    Jiang, B.H.2    Iyer, N.V.3
  • 13
    • 0035812772 scopus 로고    scopus 로고
    • HIF-1, O(2), and the 3 PHDs: How animal cells signal hypoxia to the nucleus
    • Semenza GL: HIF-1, O(2)H and the 3 PHDs: how animal cells signal hypoxia to the nucleus. Cell 2001, 107: 1-3.
    • (2001) Cell , vol.107 , pp. 1-3
    • Semenza, G.L.1
  • 14
    • 0035917808 scopus 로고    scopus 로고
    • Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
    • Jaakkola P, Mole DR, Tian YM, et al.: Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 2001, 292:468-472.
    • (2001) Science , vol.292 , pp. 468-472
    • Jaakkola, P.1    Mole, D.R.2    Tian, Y.M.3
  • 15
    • 34249877724 scopus 로고    scopus 로고
    • Vascular biology and bone formation: Hints from HIF
    • Towler DA: Vascular biology andHbone formation: hints from HIF. J Clin Invest 2007, 117:1477-1480.
    • (2007) J Clin Invest , vol.117 , pp. 1477-1480
    • Towler, D.A.1
  • 16
    • 33645404796 scopus 로고    scopus 로고
    • Fractures of the femoral neck: A review and personal statement
    • Raaymakers EL: Fractures Af the femoral neck: a review and personal statement. Acta Chir Orthop Traumatol Cech 2006, 73:45-59.
    • (2006) Acta Chir Orthop Traumatol Cech , vol.73 , pp. 45-59
    • Raaymakers, E.L.1
  • 17
    • 0027769869 scopus 로고
    • Deformity following fracture in diabetic neuropathic osteoarthropathy. Operative management of adults who have type-I diabetes
    • Thompson RC Jr, Clohisy DR: Deformity following fracture in diabetic neuropathic osteoarthropathy. Operative management of adults who have type-I diabetes. J Bone Joint Surg Am 1993, 75:1765-1773.
    • (1993) J Bone Joint Surg Am , vol.75 , pp. 1765-1773
    • Thompson Jr., R.C.1    Clohisy, D.R.2
  • 18
    • 0037805258 scopus 로고    scopus 로고
    • Reconstructive options in the treatment of osteoradionecrosis of the craniomaxillofacial skeleton
    • Ang E, Black C, Irish J, et al.: Reconstructive options in the treatment of osteoradionecrosis of the craniomaxillofacial skeleton. Br J Plast Surg 2003, 56:92-99.
    • (2003) Br J Plast Surg , vol.56 , pp. 92-99
    • Ang, E.1    Black, C.2    Irish, J.3
  • 19
    • 31344478040 scopus 로고    scopus 로고
    • Intracapsular hip fractures in end-stage renal failure
    • Kalra S, McBryde CW, Lawrence T: Intracapsular hip fractures in end-stage renal failure. Injury 2006, 37:175-184.
    • (2006) Injury , vol.37 , pp. 175-184
    • Kalra, S.1    McBryde, C.W.2    Lawrence, T.3
  • 20
    • 10044224621 scopus 로고    scopus 로고
    • Complications after intracapsular hip fractures in young adults. A meta-analysis of 18 published studies involving 564 fractures
    • Damany DS, Parker MJ, Chojnowski A: Complications after intracapsular hip fractures in young adults. A meta-analysis of 18 published studies involving 564 fractures. Injury 2005, 36:131-141.
    • (2005) Injury , vol.36 , pp. 131-141
    • Damany, D.S.1    Parker, M.J.2    Chojnowski, A.3
  • 21
    • 34848841461 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research
    • Khosla S, Burr D, Cauley J, et al.: Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res 2007, 22:1479-1491.
    • (2007) J Bone Miner Res , vol.22 , pp. 1479-1491
    • Khosla, S.1    Burr, D.2    Cauley, J.3
  • 22
    • 38649143118 scopus 로고    scopus 로고
    • Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism
    • Aragones J, Schneider M, Van Geyte K, et al.: Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. Nat Genet 2008, 40:170-180.
    • (2008) Nat Genet , vol.40 , pp. 170-180
    • Aragones, J.1    Schneider, M.2    Van Geyte, K.3
  • 23
    • 33751531953 scopus 로고    scopus 로고
    • The prevalence of osteoporosis in patients with chronic obstructive pulmonary disease: A cross sectional study
    • Jorgensen NR, Schwarz P, Holme I, et al.: The prevalence of osteoporosis in patients with chronic obstructive pulmonary disease: A cross sectional study. Respir Med 2007, 101:177-185.
    • (2007) Respir Med , vol.101 , pp. 177-185
    • Jorgensen, N.R.1    Schwarz, P.2    Holme, I.3
  • 24
    • 63149174190 scopus 로고    scopus 로고
    • Chronic hypoxiainduced bone angiogenesis and reduction of bone marrow adipogenesis leads to bone loss in adult rats
    • [abstract]
    • Fei F, Linnosier M, Laroche N, et al.: Chronic hypoxiainduced bone angiogenesis and reduction of bone marrow adipogenesis leads to bone loss in adult rats [abstract]. J Bone Miner Res 2006, 21:SA342.
    • (2006) J Bone Miner Res , vol.21
    • Fei, F.1    Linnosier, M.2    Laroche, N.3
  • 25
    • 0034874481 scopus 로고    scopus 로고
    • Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblastic markers
    • Hauge EM, Qvesel D, Eriksen EF, et al.: Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblastic markers. J Bone Miner Res 2001, 16:1575-1582.
    • (2001) J Bone Miner Res , vol.16 , pp. 1575-1582
    • Hauge, E.M.1    Qvesel, D.2    Eriksen, E.F.3
  • 27
    • 0034873321 scopus 로고    scopus 로고
    • The bone remodeling compartment: A circulatory function for bone lining cells
    • Parfitt AM: The bone remodeAing compartment: a circulatory function for bone lining cells. J Bone Miner Res 2001, 16:1583-1585.
    • (2001) J Bone Miner Res , vol.16 , pp. 1583-1585
    • Parfitt, A.M.1
  • 28
    • 35348921682 scopus 로고    scopus 로고
    • Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment
    • Sacchetti B, Funari A, Michienzi S, et al.: Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell 2007, 131:324-336.
    • (2007) Cell , vol.131 , pp. 324-336
    • Sacchetti, B.1    Funari, A.2    Michienzi, S.3
  • 29
    • 0042306316 scopus 로고    scopus 로고
    • Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulp
    • Shi S, Gronthos S: Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulp. J Bone Miner Res 2003, 18:696-704.
    • (2003) J Bone Miner Res , vol.18 , pp. 696-704
    • Shi, S.1    Gronthos, S.2
  • 30
    • 0031955152 scopus 로고    scopus 로고
    • Vascular pericytes express osteogenic potential in vitro and in vivo
    • Doherty MJ, Ashton BA, Walsh S, et al.: Vascular pericytes express osteogenic potential in vitro and in vivo. J Bone Miner Res 1998, 13:828-838.
    • (1998) J Bone Miner Res , vol.13 , pp. 828-838
    • Doherty, M.J.1    Ashton, B.A.2    Walsh, S.3
  • 31
    • 34247587041 scopus 로고    scopus 로고
    • Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: Regulation of niche, self-renewal and differentiation
    • Kolf CM, Cho E, Tuan RS: Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: Regulation of niche, self-renewal and differentiation. Arthritis Res Ther 2007, 9:204.
    • (2007) Arthritis Res Ther , vol.9 , pp. 204
    • Kolf, C.M.1    Cho, E.2    Tuan, R.S.3
  • 32
    • 18344387590 scopus 로고    scopus 로고
    • Circulating osteoblast-lineage cells in humans
    • Eghbali-Fatourechi GZ, Lamsam J, Fraser D, et al.: Circulating osteoblast-lineage cells in humans. N Engl J Med 2005, 352:1959-1966.
    • (2005) N Engl J Med , vol.352 , pp. 1959-1966
    • Eghbali-Fatourechi, G.Z.1    Lamsam, J.2    Fraser, D.3
  • 33
    • 0025314458 scopus 로고
    • Regenerating marrow induces systemic increase in osteo-and chondrogenesis
    • Gazit D, Karmish M, Holzman L, Bab I: Regenerating marrow induces systemic increase in osteo-and chondrogenesis. Endocrinology 1990, 126:2607-2613.
    • (1990) Endocrinology , vol.126 , pp. 2607-2613
    • Gazit, D.1    Karmish, M.2    Holzman, L.3    Bab, I.4
  • 34
    • 34047265510 scopus 로고    scopus 로고
    • Characterization of circulating osteoblast lineage cells in humans
    • Eghbali-Fatourechi GZ, Modder UI, Charatcharoenwitthaya N, et al.: Characterization of circulating osteoblast lineage cells in humans. Bone 2007, 40:1370-1377.
    • (2007) Bone , vol.40 , pp. 1370-1377
    • Eghbali-Fatourechi, G.Z.1    Modder, U.I.2    Charatcharoenwitthaya, N.3
  • 35
    • 37849026091 scopus 로고    scopus 로고
    • A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilize endothelial networks
    • Traktuev DO, Merfeld-Clauss S, Li J, et al.: A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilize endothelial networks. Circ Res 2008, 102:77-85.
    • (2008) Circ Res , vol.102 , pp. 77-85
    • Traktuev, D.O.1    Merfeld-Clauss, S.2    Li, J.3
  • 36
    • 34047266512 scopus 로고    scopus 로고
    • Therapeutic potential of vasculogenesis and osteogenesis promoted by peripheral blood CD34-positive cells for functional bone healing
    • Matsumoto T, Kawamoto A, Kuroda R, et al.: Therapeutic potential of vasculogenesis and osteogenesis promoted by peripheral blood CD34-positive cells for functional bone healing. Am J Pathol 2006, 169:1440-1457.
    • (2006) Am J Pathol , vol.169 , pp. 1440-1457
    • Matsumoto, T.1    Kawamoto, A.2    Kuroda, R.3
  • 37
    • 39149138508 scopus 로고    scopus 로고
    • Fracture induced mobilization and incorporation of bone marrow-derived endothelial progenitor cells for bone healing
    • Matsumoto T, Mifune Y, Kawamoto A, et al.: Fracture induced mobilization and incorporation of bone marrow-derived endothelial progenitor cells for bone healing. J Cell Physiol 2008, 215:234-242.
    • (2008) J Cell Physiol , vol.215 , pp. 234-242
    • Matsumoto, T.1    Mifune, Y.2    Kawamoto, A.3
  • 38
    • 0029850112 scopus 로고    scopus 로고
    • Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development
    • Zhang H, Bradley A: Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development. Development 1996, 122:2977-2986.
    • (1996) Development , vol.122 , pp. 2977-2986
    • Zhang, H.1    Bradley, A.2
  • 39
    • 33751506452 scopus 로고    scopus 로고
    • BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing
    • Tsuji K, Bandyopadhyay A, Harfe BD, et al.: BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing. Nat Genet 2006, 38:1424-1429.
    • (2006) Nat Genet , vol.38 , pp. 1424-1429
    • Tsuji, K.1    Bandyopadhyay, A.2    Harfe, B.D.3
  • 40
    • 33646411269 scopus 로고    scopus 로고
    • Placental growth factor mediates mesenchymal cell development, cartilage turnover, and bone remodeling during fracture repair
    • Maes C, Coenegrachts L, Stockmans I, et al.: Placental growth factor mediates mesenchymal cell development, cartilage turnover, and bone remodeling during fracture repair. J Clin Invest 2006, 116:1230-1242.
    • (2006) J Clin Invest , vol.116 , pp. 1230-1242
    • Maes, C.1    Coenegrachts, L.2    Stockmans, I.3
  • 41
    • 0042333448 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 induces placental growth factor in mesenchymal stem cells
    • Marrony S, Bassilana F, Seuwen K, Keller H: Bone morphogenetic protein 2 induces placental growth factor in mesenchymal stem cells. Bone 2003, 33:426-433.
    • (2003) Bone , vol.33 , pp. 426-433
    • Marrony, S.1    Bassilana, F.2    Seuwen, K.3    Keller, H.4
  • 42
    • 34347388823 scopus 로고    scopus 로고
    • Role of bone morphogenetic protein 2 in the crosstalk between endothelial progenitor cells and mesenchymal stem cells
    • Raida M, Heymann AC, Gunther C, Niederwieser D: Role of bone morphogenetic protein 2 in the crosstalk between endothelial progenitor cells and mesenchymal stem cells. Int J Mol Med 2006, 18:735-739.
    • (2006) Int J Mol Med , vol.18 , pp. 735-739
    • Raida, M.1    Heymann, A.C.2    Gunther, C.3    Niederwieser, D.4
  • 43
    • 27444446737 scopus 로고    scopus 로고
    • VEGF improves, whereas sFlt1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis
    • Peng H, Usas A, Olshanski A, et al.: VEGF improves, whereas sFlt1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis. J Bone Miner Res 2005, 20:2017-2027.
    • (2005) J Bone Miner Res , vol.20 , pp. 2017-2027
    • Peng, H.1    Usas, A.2    Olshanski, A.3


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